MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hyperpituitarism

(UMLS:C0020506)

Definition:: Disease of the glandular, anterior portion of the pituitary (PITUITARY GLAND, ANTERIOR) resulting in hypersecretion of ADENOHYPOPHYSEAL HORMONES such as GROWTH HORMONE; PROLACTIN; THYROTROPIN; LUTEINIZING HORMONE; FOLLICLE STIMULATING HORMONE ; and ADRENOCORTICOTROPIC HORMONE. Hyperpituitarism usually is caused by a functional ADENOMA.
UMLS ID:: C0020506
MeSH ID:: D006964

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.617.738.250

Classification 2:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.700.355

Synonym(s)

Hyperpituitarism

Anterior pituitary hyperfunction

Hyperpituitarism, NOS

Pituitary hyperfunction

Pituitary hyperfunction (ant.)

Pituitary hyperfunction, NOS

anterior pituitary hyperfunction

hyperfunction; pituitary

hyperpituitarism

10.

pituitary; hyperfunction

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Bromocriptine	FAERS: 1	US FAERS
2	Droxidopa	FAERS: 1	US FAERS
3	Hydrocortisone	FAERS: 1	US FAERS
4	Sitagliptin Phosphate	FAERS: 1	US FAERS
5	Teriparatide	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Empty Sella Syndrome	46.2%
2	Hypopituitarism	46.2%
3	Hypophysitis	46.2%
4	Pituitary Apoplexy	34.2%
5	Pituitary Adenoma	27.6%
6	Pituitary Neoplasms	27.6%
7	Prolactinoma	22.2%
8	Growth Hormone-Secreting Pituitary Adenoma	22.2%
9	Nelson Syndrome	21.3%
10	Akinetic Mutism	19.6%
11	Anoxic Encephalopathy	19.6%
12	Basal Ganglia Diseases	19.6%
13	Brain Damage, Chronic	19.6%
14	Cerebellar Diseases	19.6%
15	Encephalitis	19.6%
16	Encephalomalacia	19.6%
17	Epilepsy	19.6%
18	Hydrocephalus	19.6%
19	Congenital Hydrocephalus	19.6%
20	Thalamic Diseases	19.6%
21	Intracranial Hypertension	19.6%
22	Aura	19.6%
23	Leukoencephalopathy	19.6%
24	Neuroaxonal Dystrophies	19.6%
25	Headache Disorders	19.6%
26	Intracranial Hypotension	19.6%
27	Brain Edema	19.6%
28	Brain Hypoxia	19.6%
29	Aqueductal Stenosis	19.6%
30	Subdural Effusion	18.3%
31	Encephalomyelitis	17.9%
32	Meningoencephalitis	16.5%
33	Diabetes Insipidus	16.2%
34	Meningitis	15.4%
35	Movement Disorders	15.4%
36	Pachymeningitis	15.4%
37	Spinal Cord Diseases	15.4%
38	Parkinsonian Disorders	14.9%
39	Brain Diseases, Metabolic	14.9%
40	Cerebrovascular Disorders	14.9%
41	Cerebrovascular Insufficiency	14.9%
42	Dementia	14.9%
43	Adrenal Gland Diseases	14.4%
44	Gonadal Disorders	14.4%
45	Parathyroid Diseases	14.4%
46	Thyroid Diseases	14.4%
47	Posterior Leukoencephalopathy Syndrome	14.3%
48	Posterior reversible encephalopathy syndrome	14.3%
49	Dandy-Walker Syndrome	14.2%
50	Pneumocephalus	14.1%
51	Brain Abscess	14%
52	Multiple System Atrophy	14%
53	Basal Ganglia Cerebrovascular Disease	13.9%
54	Brain Injuries	13.4%
55	Brain Neoplasms	13.3%
56	Dementia, Vascular	13.3%
57	Ocular Motility Disorders	12.9%
58	Cyclophoria	12.9%
59	Marchiafava-Bignami Disease	12.7%
60	Lewy Body Disease	12.6%
61	Myelitis	12.6%
62	Meige Syndrome	12.3%
63	Cerebral Ventriculitis	12.3%
64	Epilepsy, Post-Traumatic	12.3%
65	Central Nervous System Infection	12.1%
66	Brain Death	12.1%
67	Cerebral Palsy	11.6%
68	Epilepsies, Partial	11.6%
69	Epilepsy, Generalized	11.6%
70	Pseudotumor Cerebri	11.6%
71	Hypertensive Encephalopathy	11.6%
72	Simple Partial Seizures	11.6%
73	Epilepsy, Reflex	11.6%
74	Headache Disorders, Primary	11.6%
75	Headache Disorders, Secondary	11.6%
76	Medication overuse headache	11.6%
77	Leukomalacia, Periventricular	11.6%
78	Vascular Headaches	11.5%
79	Hypoxia-Ischemia, Brain	11.4%
80	Myoclonic Epilepsy	11.4%
81	Epilepsy, Temporal Lobe	11.4%
82	Epilepsy, Rolandic	11.4%
83	Benign Rolandic Epilepsy	11.4%
84	Adrenal Gland Neoplasms	11%
85	Bone Diseases, Endocrine	10.8%
86	Endocrine Gland Neoplasms	10.8%
87	Epidural Abscess	10.7%
88	Parkinson Disease	10.7%
89	Diabetes Mellitus	10.6%
90	Amblyopia	10.6%
91	Prion Diseases	10.2%
92	Cranial nerve diseases	10.2%
93	Demyelinating Diseases	10.2%
94	Demyelination	10.2%
95	Neuromuscular Diseases	10.2%
96	Chronobiology Disorders	10.2%
97	Neuroleptic Malignant Syndrome	10.1%
98	Myelinolysis, Central Pontine	10.1%
99	Cerebellar Neoplasms	10%
100	Creutzfeldt-Jakob disease	9.9%
101	Huntington Disease	9.7%
102	Dystonia Musculorum Deformans	9.6%
103	Stiff-Person Syndrome	9.4%
104	Adrenal Cortex Diseases	9.1%
105	Euthyroid Sick Syndromes	9.1%
106	Goiter	9.1%
107	Hyperparathyroidism	9.1%
108	Hyperthyroidism	9.1%
109	Hyperthyroxinemia	9.1%
110	Hypogonadism	9.1%
111	Hypoparathyroidism	9.1%
112	Hypothyroidism	9.1%
113	Delayed Puberty	9.1%
114	Precocious Puberty	9.1%
115	Thyroiditis	9.1%
116	Hypogonadotropic hypogonadism	9.1%
117	Testotoxicosis	9.1%
118	Secondary hypothyroidism	9.1%
119	Primary Hyperthyroidism	9.1%
120	Primary Hypothyroidism	9.1%
121	Parathyroid Neoplasms	9.1%
122	Thyroid Neoplasm	9.1%
123	Thyroid carcinoma	9.1%
124	Carotid Artery Diseases	8.7%
125	Brain Ischemia	8.7%
126	Cerebrovascular accident	8.7%
127	Kluver-Bucy Syndrome	8.7%
128	Vasospasm, Intracranial	8.7%
129	Intracranial Arterial Diseases	8.7%
130	Amnesia, Transient Global	8.7%
131	Presenile dementia	8.6%
132	Senile dementia	8.6%
133	Progressive supranuclear palsy	8.6%
134	Juvenile Myoclonic Epilepsy	8.5%
135	Myoclonic Epilepsies, Progressive	8.5%
136	Dwarfism	8.5%
137	Spinal Cord Injuries	8.5%
138	Striatonigral Degeneration	8.5%
139	Arachnoiditis	8.4%
140	Aseptic Meningitis	8.4%
141	Syringomyelia	8.4%
142	Essential Tremor	8.4%
143	Familial Tremor	8.4%
144	Pneumorrhachis	8.4%
145	Writer's Cramp	8.4%
146	Spinal Muscular Atrophy	8.4%
147	Progressive Muscular Atrophy	8.4%
148	Limbic Encephalitis	8.2%
149	Asterixis	8.1%
150	Ballismus	8.1%
151	Meningitis, Bacterial	8%
152	Meningitis, Fungal	8%
153	Leukoencephalopathy, Progressive Multifocal	8%
154	Subacute Combined Degeneration	8%
155	Trauma, Nervous System	7.9%
156	Brain Injuries, Diffuse	7.9%
157	Traumatic Brain Injury	7.9%
158	Cerebellar Ataxia	7.8%
159	Supratentorial Neoplasms	7.8%
160	Motor Neuron Disease	7.8%
161	Basal Ganglia Hemorrhage	7.8%
162	Post-Traumatic Headache	7.7%
163	Tension Headache	7.7%
164	Epilepsy, Complex Partial	7.7%
165	Migraine Disorders	7.7%
166	Abdominal Migraine	7.7%
167	Status Migrainosus	7.7%
168	Cervicogenic Headache	7.7%
169	Nervous System Neoplasms	7.6%
170	Neurologic Manifestations	7.6%
171	Neurotoxicity Syndromes	7.6%
172	Brain Infarction	7.6%
173	Persistent Vegetative State	7.5%
174	Poliomyelitis	7.5%
175	Shy-Drager Syndrome	7.3%
176	Vasculitis, Central Nervous System	7.2%
177	Paraneoplastic Cerebellar Degeneration	7.2%
178	Lupus Vasculitis, Central Nervous System	7.1%
179	Amyotrophic Lateral Sclerosis	7.1%
180	Diabetic Neuropathies	7.1%
181	Diabetic Amyotrophy	7.1%
182	Diabetic Autonomic Neuropathy	7.1%
183	Chronic Fatigue Syndrome	7.1%
184	MPTP Poisoning	7.1%
185	Reye Syndrome	7%
186	Hepatolenticular Degeneration	7%
187	Adrenocortical carcinoma	7%
188	Intracranial Embolism and Thrombosis	6.9%
189	Hepatic Encephalopathy	6.9%
190	Testicular Diseases	6.9%
191	Graves Disease	6.8%
192	Ovarian Diseases	6.8%
193	Brain Hemorrhage, Traumatic	6.8%
194	Carotid Artery Injuries	6.7%
195	Congenital Hypothyroidism	6.7%
196	Cushing Syndrome	6.7%
197	Hyperaldosteronism	6.7%
198	Hyperparathyroidism, Secondary	6.7%
199	Hypoaldosteronism	6.7%
200	Thyrotoxicosis	6.7%
201	Hyperparathyroidism, Primary	6.7%
202	Thyroid Hormone Resistance Syndrome	6.7%
203	ovarian neoplasm	6.7%
204	Spinal Cord Neoplasms	6.6%
205	Thyroid Nodule	6.6%
206	Encephalomyelitis, Acute Disseminated	6.6%
207	Leukoencephalitis, Acute Hemorrhagic	6.6%
208	Toxoplasmosis, Cerebral	6.5%
209	Central Nervous System Fungal Infections	6.4%
210	Conus Medullaris Syndrome	6.4%
211	Spinal Cord Vascular Diseases	6.4%
212	Ophthalmoplegic Migraine	6.4%
213	Sleep Wake Disorders	6.2%
214	Lafora Disease	6.1%
215	Unverricht-Lundborg Syndrome	6.1%
216	Restless Legs Syndrome	6.1%
217	Friedreich Ataxia	6.1%
218	Miller Fisher Syndrome	6%
219	Autonomic Dysreflexia	6%
220	Complex Regional Pain Syndromes	6%
221	Putaminal Hemorrhage	6%
222	Polyradiculoneuropathy	5.9%
223	Polyradiculoneuritis	5.9%
224	Testicular Neoplasms	5.9%
225	Brain Diseases, Metabolic, Inborn	5.8%
226	Akathisia, Drug-Induced	5.8%
227	Cluster Headache	5.8%
228	Migraine with Aura	5.8%
229	Familial Hemiplegic Migraine	5.8%
230	Chronic Paroxysmal Hemicrania	5.8%
231	SUNCT Syndrome	5.8%
232	Paroxysmal Hemicrania	5.8%
233	Cerebral Arterial Diseases	5.7%
234	Vertebrobasilar Insufficiency	5.7%
235	Basilar Artery Stenosis	5.7%
236	Vertebral Artery Stenosis	5.7%
237	Intracranial Hemorrhage, Hypertensive	5.7%
238	Transient Cerebral Ischemia	5.7%
239	Moyamoya Disease	5.7%
240	Mitochondrial Encephalomyopathies	5.6%
241	Cerebral Infarction	5.6%
242	Brain Stem Infarctions	5.6%
243	Canavan Disease	5.6%
244	Alexander Disease	5.6%
245	Infarction, Middle Cerebral Artery	5.6%
246	Infarction, Anterior Cerebral Artery	5.6%
247	Infarction, Posterior Cerebral Artery	5.6%
248	Hyperglycemic Hyperosmolar Nonketotic Coma	5.5%
249	Hashimoto Disease	5.5%
250	Diabetic Foot	5.5%
251	Gestational Diabetes	5.5%
252	Latent Autoimmune Diabetes in Adults	5.5%
253	Myelitis, Transverse	5.4%
254	Diabetes Mellitus, Experimental	5.4%
255	Opsoclonus-Myoclonus Syndrome	5.2%
256	Diffuse Axonal Injury	5.2%
257	Brain Stem Neoplasms	5.2%
258	Adrenoleukodystrophy	5.2%
259	Central Nervous System Bacterial Infections	5.2%
260	Dysautonomia	5.1%
261	Vagus Nerve Disorder	5.1%
262	Glossopharyngeal Neuralgia	5.1%
263	Abducens Nerve Diseases	5.1%
264	Heavy Metal Poisoning, Nervous System	5.1%
265	Neuromuscular Junction Diseases	5.1%
266	Tauopathies	5.1%
267	Trochlear Nerve Diseases	5.1%
268	Peripheral Nervous System Diseases	5.1%
269	Addison Disease	5.1%
270	Diabetic Angiopathies	5.1%
271	Autoimmune thyroiditis	5.1%
272	Primary Adrenal Insufficiency	5.1%
273	Myxedema	5%
274	Orchitis	5%
275	Diabetic Cardiomyopathies	5%
276	Ovarian Hyperstimulation Syndrome	5%
277	Wernicke Encephalopathy	4.9%
278	AIDS Dementia Complex	4.9%
279	Auditory Perceptual Disorders	4.9%
280	Tuberculosis, Meningeal	4.9%
281	Dyskinesia, Drug-Induced	4.8%
282	Peripheral Nerve Injuries	4.8%
283	Myasthenia Gravis	4.7%
284	Scrapie	4.7%
285	Central Cord Syndrome	4.7%
286	Lateral Medullary Syndrome	4.7%
287	Chorea	4.6%
288	Frontotemporal dementia	4.6%
289	Carotid Stenosis	4.6%
290	Intracranial Aneurysm	4.6%
291	Intracranial Arteriosclerosis	4.6%
292	Cerebral Atherosclerosis	4.6%
293	Subarachnoid Hemorrhage	4.6%
294	Cerebral Arteriosclerosis	4.6%
295	Cerebral Hemorrhage	4.6%
296	Cerebral Thrombosis	4.6%
297	Intracranial Embolism	4.6%
298	Intracranial Thrombosis	4.6%
299	Hermaphroditism	4.6%
300	Disorders of Sex Development	4.6%
301	Kallmann Syndrome	4.5%
302	granulosa cell tumor	4.5%
303	Carcinoma, Ovarian Epithelial	4.5%
304	Vertebral Artery Dissection	4.5%
305	MELAS Syndrome	4.4%
306	Kernicterus	4.4%
307	Brain Contusion	4.3%
308	Subarachnoid Hemorrhage, Traumatic	4.3%
309	Carotid Artery, Internal, Dissection	4.3%
310	Subclavian Steal Syndrome	4.3%
311	Pick Disease of the Brain	4.3%
312	Progressive bulbar palsy	4.2%
313	Bulbar palsy	4.2%
314	Subacute Sclerosing Panencephalitis	4.1%
315	Meningitis, Cryptococcal	4.1%
316	Sleep Disorders, Circadian Rhythm	4.1%
317	Meningitis, Listeria	4.1%
318	Meningitis, Haemophilus	4.1%
319	Meningitis, Pneumococcal	4.1%
320	Myopathy	4%
321	Optic Neuropathy	4%
322	Corpus Luteum Cyst	4%
323	Ovarian Cysts	4%
324	Guillain-Barre Syndrome	4%
325	Diabetic Nephropathy	4%
326	Lambert-Eaton Myasthenic Syndrome	4%
327	Klinefelter Syndrome	4%
328	Anovulation	3.9%
329	Diabetic Ketoacidosis	3.9%
330	Oophoritis	3.9%
331	Ataxia Telangiectasia	3.9%
332	Multiple Endocrine Neoplasia	3.9%
333	Pancreatic Neoplasm	3.9%
334	Botulism	3.9%
335	Torticollis	3.9%
336	Central Nervous System Cysts	3.9%
337	Facial Nerve Diseases	3.9%
338	Craniocerebral Trauma	3.9%
339	Parasomnia	3.9%
340	Dyssomnias	3.9%
341	Choroid Plexus Papilloma	3.9%
342	Brain Concussion	3.9%
343	Vestibulocochlear Nerve Diseases	3.8%
344	Decerebrate State	3.8%
345	Hemiparesis	3.8%
346	Hydranencephaly	3.8%
347	Meningism	3.8%
348	Neural Tube Defects	3.8%
349	Paresis	3.8%
350	Seizures	3.8%
351	Sensation Disorders	3.8%
352	Tethered Cord Syndrome	3.8%
353	Central Nervous System Neoplasms	3.8%
354	Complex partial seizures	3.8%
355	Iniencephaly	3.8%
356	Craniorachischisis	3.8%
357	Exencephaly	3.8%
358	Monoparesis	3.8%
359	Septo-Optic Dysplasia	3.8%
360	Cortical Dysplasia	3.8%
361	Neurogenic Inflammation	3.8%
362	Gait Disorders, Neurologic	3.8%
363	Neuromuscular Manifestations	3.8%
364	Malformations of Cortical Development	3.8%
365	Sweating, Gustatory	3.8%
366	Auriculotemporal Syndrome	3.8%
367	Carotid Artery Thrombosis	3.8%
368	Spinal Cord Ischemia	3.7%
369	Tuberculosis, Central Nervous System	3.7%
370	Causalgia	3.6%
371	Olfactory Nerve Injuries	3.6%
372	Giant Cell Arteritis	3.5%
373	Temporal Arteritis	3.5%
374	Cerebral Amyloid Angiopathy	3.4%
375	Sinus Thrombosis, Intracranial	3.4%
376	Leydig Cell Tumor	3.4%
377	Cryptorchidism	3.4%
378	Diabetic Retinopathy	3.4%
379	Alice in Wonderland Syndrome	3.4%
380	Horner Syndrome	3.3%
381	Multiple Sclerosis	3.3%
382	Reflex Sympathetic Dystrophy	3.3%
383	Nocturnal Myoclonus Syndrome	3.3%
384	Waterhouse-Friderichsen Syndrome	3.3%
385	Gonadal Dysgenesis	3.3%
386	Adrenogenital Syndrome	3.3%
387	Ovotesticular Disorders of Sex Development	3.3%
388	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	3.3%
389	Polycystic Ovary Syndrome	3.3%
390	Hyperandrogenism	3.2%
391	Pupil Disorders	3.2%
392	Neurobehavioral Manifestations	3.2%
393	Neuromyelitis Optica	3.1%
394	Paraneoplastic Encephalomyelitis	3.1%
395	Facial Nerve Injuries	3.1%
396	Uveomeningoencephalitic Syndrome	3.1%
397	Sturge-Weber Syndrome	3%
398	Vertigo	3%
399	Alcohol-Induced Disorders, Nervous System	3%
400	Refsum Disease	3%
401	Neuroaspergillosis	3%
402	Tardive Dyskinesia	2.9%
403	West Nile Fever	2.9%
404	Jet Lag Syndrome	2.9%
405	Galactosemias	2.8%
406	Urea Cycle Disorders, Inborn	2.8%
407	Tyrosinemias	2.8%
408	Multiple Endocrine Neoplasia Type 1	2.8%
409	Cavernous Sinus Thrombosis	2.8%
410	Sagittal Sinus Thrombosis	2.8%
411	Ophthalmoplegia	2.8%
412	External Ophthalmoplegia	2.8%
413	Neuritis	2.8%
414	Polyneuritis	2.8%
415	Radiculitis	2.8%
416	Polyneuropathy	2.8%
417	Mononeuritis	2.8%
418	Mononeuropathies	2.8%
419	Brachial Plexus Neuropathies	2.8%
420	Radiculopathy	2.8%
421	Mononeuropathy Multiplex	2.8%
422	Nerve Root Compression	2.8%
423	Hematoma, Subdural	2.7%
424	Hematoma, Epidural, Cranial	2.7%
425	Myasthenia Gravis, Autoimmune, Experimental	2.7%
426	Acrodynia	2.6%
427	Tuberous Sclerosis	2.6%
428	Pseudorabies	2.6%
429	Fabry Disease	2.6%
430	Voice Disorders	2.6%
431	Voice Disturbance	2.6%
432	Homocystinuria	2.5%
433	Smith-Magenis syndrome	2.5%
434	Leigh Disease	2.5%
435	Dural Arteriovenous Fistula	2.5%
436	Brachial Plexus Neuritis	2.5%
437	Neuralgic Amyotrophy	2.5%
438	Anterior Spinal Artery Syndrome	2.5%
439	Neurosyphilis	2.5%
440	Vocal Cord Paralysis	2.4%
441	Charcot-Marie-Tooth Disease	2.3%
442	Myotonia Congenita	2.2%
443	Cerebrospinal Fluid Otorrhea	2.2%
444	Cerebrospinal Fluid Rhinorrhea	2.2%
445	Neuritis, Autoimmune, Experimental	2.2%
446	Gait Ataxia	2.2%
447	Carcinoma, Pancreatic Ductal	2.2%
448	Menkes Kinky Hair Syndrome	2.2%
449	Hematoma, Subdural, Intracranial	2.2%
450	Hematoma, Subdural, Chronic	2.2%
451	Hematoma, Subdural, Acute	2.2%
452	Turner Syndrome	2.2%
453	Coma, Post-Head Injury	2.1%
454	Reflex, Abnormal	2.1%
455	Hyporeflexia	2.1%
456	Hyperreflexia	2.1%
457	Myositis	2.1%
458	Optic Atrophy	2.1%
459	Optic Neuritis	2.1%
460	Papilledema	2.1%
461	Strabismus	2.1%
462	Tolosa-Hunt Syndrome	2.1%
463	Isaacs syndrome	2.1%
464	Arsenic Poisoning	2.1%
465	Myotonic Disorders	2.1%
466	Myasthenic Syndromes, Congenital	2.1%
467	Lyme Neuroborreliosis	2.1%
468	Facial Injuries	2.1%
469	Facial Neuralgia	2.1%
470	Sleep Talking	2.1%
471	Manganese Poisoning	2.1%
472	Sleep Disorders, Intrinsic	2.1%
473	Orthostatic intolerance	2.1%
474	Anosmia	2.1%
475	Ataxia	2.1%
476	Athetosis	2.1%
477	Catalepsy	2.1%
478	Dystonia	2.1%
479	Hemiplegia	2.1%
480	Locked-In Syndrome	2.1%
481	Meningeal Neoplasms	2.1%
482	Meningomyelocele	2.1%
483	Muscle Hypertonia	2.1%
484	Muscle hypotonia	2.1%
485	Myoclonus	2.1%
486	Myotonia	2.1%
487	Neuralgia	2.1%
488	Paraplegia	2.1%
489	Pseudobulbar Palsy	2.1%
490	Quadriplegia	2.1%
491	Spasm	2.1%
492	Spastic Paraplegia	2.1%
493	Status Epilepticus	2.1%
494	Taste Disorders	2.1%
495	Tremor	2.1%
496	Spina Bifida	2.1%
497	Monoplegia	2.1%
498	Hypokinesia	2.1%
499	Paraparesis	2.1%
500	Bradykinesia	2.1%
501	Waxy flexibility	2.1%
502	Action Tremor	2.1%
503	Resting Tremor	2.1%
504	Dysosmia	2.1%
505	Quadriparesis	2.1%
506	Mercury Poisoning, Nervous System	2.1%
507	Olfaction Disorders	2.1%
508	Myokymia	2.1%
509	Lead Poisoning, Nervous System	2.1%
510	Vestibular Neuronitis	2.1%
511	Somatosensory Disorders	2.1%
512	Neuropathic pain	2.1%
513	Hyperkinesia	2.1%
514	Intention tremor	2.1%
515	Alcohol Withdrawal Seizures	2.1%
516	Tarsal Tunnel Syndrome	2%
517	Cauda Equina Syndrome	2%
518	insulinoma	2%
519	Gastrinoma	2%
520	Glucagonoma	2%
521	Carcinoma, Endometrioid	2%
522	Toxoplasmosis, Congenital	2%
523	Malaria, Cerebral	2%
524	Neurocysticercosis	2%
525	Multiple Sclerosis, Chronic Progressive	2%
526	Multiple Sclerosis, Relapsing-Remitting	2%
527	Zellweger Syndrome	1.9%
528	Carbamoyl-Phosphate Synthase I Deficiency Disease	1.9%
529	Akathisia	1.9%
530	Restlessness	1.9%
531	Psychomotor Agitation	1.9%
532	Myotonic Dystrophy	1.8%
533	Renal Osteodystrophy	1.8%
534	Renal rickets	1.8%
535	Vipoma	1.8%
536	Hand-Arm Vibration Syndrome	1.8%
537	Vision Disorders	1.7%
538	Metamorphopsia	1.7%
539	Visual Impairment	1.7%
540	Fibromyalgia	1.7%
541	Optic Neuropathy, Ischemic	1.7%
542	Anterior Ischemic Optic Neuropathy	1.7%
543	Medial Tibial Stress Syndrome	1.7%
544	Facial Hemiatrophy	1.7%
545	Melkersson-Rosenthal Syndrome	1.7%
546	Mitochondrial Myopathies	1.7%
547	Glycogen storage disease type II	1.7%
548	Anisocoria	1.7%
549	Confusion	1.7%
550	Facial paralysis	1.7%
551	Lethargy	1.7%
552	Memory Disorders	1.7%
553	Muscle Cramp	1.7%
554	Perceptual Disorders	1.7%
555	Psychomotor Disorders	1.7%
556	Tonic Pupil	1.7%
557	Eosinophilia-Myalgia Syndrome	1.7%
558	Anhedonia	1.7%
559	Disorientation	1.7%
560	Facial Paresis	1.7%
561	Memory Loss	1.7%
562	Hemisensory Neglect	1.7%
563	Dysacusis	1.7%
564	Sleep Bruxism	1.7%
565	Anencephaly	1.7%
566	Meningocele	1.7%
567	Muscular Atrophy	1.7%
568	Respiratory Paralysis	1.7%
569	Encephalocele	1.7%
570	Sciatic Neuropathy	1.7%
571	Ulnar Neuropathies	1.7%
572	Lesion of Sciatic Nerve	1.7%
573	Ulnar Neuritis	1.7%
574	Radial nerve compression	1.7%
575	Radial Tunnel Syndrome	1.7%
576	Peroneal Neuropathies	1.7%
577	Radial Neuropathy	1.7%
578	Median Neuropathy	1.7%
579	Sciatic Nerve Palsy	1.7%
580	Femoral Neuropathy	1.7%
581	Tibial Neuropathy	1.7%
582	Ulnar Nerve Palsy	1.7%
583	Postural Orthostatic Tachycardia Syndrome	1.7%
584	Radial nerve palsy	1.7%
585	Tetany	1.7%
586	Carpal Tunnel Syndrome	1.6%
587	neurofibroma	1.6%
588	Gait Apraxia	1.6%
589	Sciatica	1.6%
590	Alstrom Syndrome	1.5%
591	Acoustic Neuroma	1.5%
592	Optic Nerve Glioma	1.5%
593	Amyloid Neuropathies, Familial	1.5%
594	Duane Retraction Syndrome	1.4%
595	Consciousness Disorders	1.4%
596	Mental Retardation	1.4%
597	Muscle Weakness	1.4%
598	Depressed Level of Consciousness	1.4%
599	Mental deficiency	1.4%
600	Intellectual Disability	1.4%
601	Mobius Syndrome	1.4%
602	Bell Palsy	1.4%
603	Catatonia	1.4%
604	Herpes Zoster Oticus	1.4%
605	Familial Periodic Paralysis	1.4%
606	Aphonia	1.4%
607	Sleep Deprivation	1.4%
608	Dysphonia	1.4%
609	Cubital Tunnel Syndrome	1.3%
610	Gaucher Disease	1.3%
611	Thoracic Outlet Syndrome	1.3%
612	Esotropia	1.2%
613	Exotropia	1.2%
614	Hypotension, Orthostatic	1.2%
615	Sleep Apnea Syndromes	1.2%
616	Polymyositis	1.2%
617	Post-Exercise Hypotension	1.2%
618	Disorders of Excessive Somnolence	1.2%
619	Sleep Initiation and Maintenance Disorders	1.2%
620	Night Terrors	1.2%
621	Somnambulism	1.2%
622	Trigeminal Nerve Disorder	1.2%
623	Transient Insomnia	1.2%
624	Sleep Paralysis	1.2%
625	Chronic Insomnia	1.2%
626	REM Sleep Behavior Disorder	1.2%
627	Hypersomnia	1.2%
628	Dermal Sinus	1.2%
629	Dysgeusia	1.2%
630	Formication	1.2%
631	Hyperalgesia	1.2%
632	Hyperesthesia	1.2%
633	Hypesthesia	1.2%
634	Language Disorders	1.2%
635	Numbness	1.2%
636	Paresthesia	1.2%
637	Paraparesis, Spastic	1.2%
638	Spina Bifida Cystica	1.2%
639	Trismus	1.2%
640	Spina Bifida Occulta	1.2%
641	Epilepsia Partialis Continua	1.2%
642	Hypogeusia	1.2%
643	Meningeal Carcinomatosis	1.2%
644	Brown-Sequard Syndrome	1.2%
645	Lissencephaly	1.2%
646	Polymicrogyria	1.2%
647	Pachygyria	1.2%
648	Schizencephaly	1.2%
649	Lockjaw	1.2%
650	Allodynia	1.2%
651	Lead Poisoning, Nervous System, Childhood	1.2%
652	Lead Poisoning, Nervous System, Adult	1.2%
653	Periventricular Nodular Heterotopia	1.2%
654	Ageusia	1.2%
655	Myalgia	1.2%
656	Neuronal Ceroid-Lipofuscinoses	1.2%
657	Classical Lissencephalies and Subcortical Band Heterotopias	1.2%
658	Denys-Drash Syndrome	1.2%
659	Polyradiculopathy	1.1%
660	Tay-Sachs Disease	1.1%
661	Aicardi's syndrome	1.1%
662	Hoarseness	1%
663	Niemann-Pick Disease, Type C	1%
664	Cockayne Syndrome	1%
665	Alcohol Withdrawal Delirium	1%
666	Eye Injuries	1%
667	Muscular Dystrophy	1%
668	Congenital nystagmus	1%
669	Orbital Myositis	1%
670	Diplopia	1%
671	Muscle Rigidity	1%
672	Muscle Spasticity	1%
673	Scotoma	1%
674	Photophobia	1%
675	Cogwheel Rigidity	1%
676	Hemifacial Spasm	1%
677	Amaurosis	1%
678	Blindness	1%
679	Nuchal Rigidity	1%
680	Pyomyositis	1%
681	Agnosia	1%
682	Apraxias	1%
683	Hallucinations	1%
684	Hemianopsia	1%
685	Hyperacusis	1%
686	Tinnitus	1%
687	Visual Agnosia	1%
688	Anosognosia	1%
689	Wernicke-Korsakoff Syndrome	1%
690	Phonophobia	1%
691	Hearing Loss	1%
692	Sarcopenia	1%
693	Alexia	0.9%
694	Dyslexia	0.9%
695	Holoprosencephaly	0.9%
696	Optic Atrophy, Hereditary, Leber	0.9%
697	Amnesia	0.8%
698	Delirium	0.8%
699	Dissociative Amnesia	0.8%
700	Color blindness	0.8%
701	Global Amnesia	0.8%
702	Cri-du-Chat Syndrome	0.8%
703	Down Syndrome	0.8%
704	Trisomy 21	0.8%
705	POEMS Syndrome	0.8%
706	Meningioma	0.8%
707	Williams Syndrome	0.8%
708	Microcephaly	0.8%
709	Macrocephaly	0.8%
710	Sleep Apnea, Obstructive	0.8%
711	Sleep Apnea, Central	0.8%
712	Hypokalemic periodic paralysis	0.8%
713	Narcolepsy	0.8%
714	Trigeminal Neuralgia	0.8%
715	Kleine-Levin Syndrome	0.8%
716	Agraphia	0.8%
717	Anomia	0.8%
718	Cluttering	0.8%
719	Language Development Disorders	0.8%
720	Speech Disorders	0.8%
721	Syncope	0.8%
722	Stupor	0.8%
723	Dysgraphia	0.8%
724	Presyncope	0.8%
725	Dyslalia	0.8%
726	Porencephaly	0.8%
727	Kearns-Sayre syndrome	0.8%
728	Neurofibrosarcoma	0.8%
729	Prader-Willi Syndrome	0.7%
730	Phantom pain	0.7%
731	Phantom Limb Pain	0.7%
732	Eye Burns	0.7%
733	Welander Distal Myopathy	0.7%
734	Amaurosis Fugax	0.7%
735	Blindness, Cortical	0.7%
736	Dyscalculia	0.7%
737	Rett Syndrome	0.7%
738	Deafness	0.7%
739	Hearing Loss, Sudden	0.7%
740	Gerstmann Syndrome	0.7%
741	Hearing Loss, Bilateral	0.7%
742	Hearing Loss, High-Frequency	0.7%
743	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
744	Prosopagnosia	0.7%
745	Apraxia, Ideomotor	0.7%
746	Charles Bonnet Syndrome	0.7%
747	Hearing Loss, Unilateral	0.7%
748	Complete Hearing Loss	0.7%
749	Alien Hand Syndrome	0.7%
750	Deaf Mutism	0.7%
751	Cataplexy	0.6%
752	Aphasia	0.6%
753	Articulation Disorders	0.6%
754	Echolalia	0.6%
755	Stuttering	0.6%
756	Dysphasia	0.6%
757	Dermatomyositis	0.6%
758	Corneal Scar	0.6%
759	Rubinstein-Taybi Syndrome	0.6%
760	Muscular Dystrophy, Duchenne	0.5%
761	Retrograde amnesia	0.5%
762	Amnesia, Anterograde	0.5%
763	Dysarthria	0.5%
764	Mutism	0.5%
765	Selective Mutism	0.5%
766	Fragile X Syndrome	0.5%
767	Corneal Perforation	0.4%
768	Alexia, Pure	0.4%
769	Mucopolysaccharidosis II	0.3%

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