MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Respiratory Insufficiency

(UMLS:C0035229)

Definition:: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)
UMLS ID:: C0035229
MeSH ID:: D012131

Classification:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.618.846

Synonym(s)

Respiratory Insufficiency

Impairment;respiratory

RESPIRATORY FUNCTION IMPAIRED

RESPIRATORY INSUFFICIENCY

Respiratory impairment

Respiratory insufficiency

Respiratory insufficiency, NOS

function impaired respiratory

impaired respiratory function

10.

insufficiency respiratory

11.

insufficiency; respiratory

12.

progressive respiratory failure

13.

respiratory function impaired

14.

respiratory insufficiency

15.

respiratory; insufficiency

Associated Drug(s)

	Name	Reference(s)	Data Source
1	20682-S	6129881	CTD
2	4-Aminopyridine	6784740	CTD
3	4-hydroxybutyric acid	25480120	CTD
4	AR C155858	25480120	CTD
5	Acetaminophen	6476315	CTD
6	Acetazolamide	2712085	CTD
7	Acrolein	27592100	CTD
8	Alcohols	17414256	CTD
9	Alfaxalone Alfadolone Mixture	5115032	CTD
10	Alfentanil	2311153 9037435 16563328	CTD
11	Almitrine	6110396	CTD
12	Alphaprodine	3422794	CTD
13	Amiodarone	2842116 3799544 24729111	CTD
14	Amitriptyline	12818949	CTD
15	Amobarbital	3777263	CTD
16	Amoxicillin-Potassium Clavulanate Combination	19078840	CTD
17	Analgesics, Opioid	20376769	CTD
18	Apomorphine	6815	CTD
19	Aprepitant		SIDER
20	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	20440598	CTD
21	Atracurium	2751916 10457883	CTD
22	Atropine	3422794	CTD
23	Azithromycin	8701248	CTD
24	Baclofen	16859228 29945230	CTD
25	Bisoprolol		SIDER
26	Bleomycin	5027400	CTD
27	Bortezomib		SIDER
28	Bupivacaine	1530175 9620513 9698952	CTD SIDER
29	Buprenorphine	View details 4025755 11812504 16547090 16764215 17015570 17914664 19819313	CTD
30	Butorphanol	17909753	CTD
31	Cefotetan	1554932	CTD
32	Chlorambucil	7410114	CTD
33	Chloramphenicol	6416440	CTD
34	Chloroform	5138029	CTD
35	Chlorpheniramine	709472	CTD
36	Chlorpromazine	283080	CTD
37	Ciguatoxins	5642309	CTD
38	Cimetidine	7085965	CTD
39	Ciprofloxacin	11145498	CTD
40	Citalopram	22951378	CTD
41	Clobazam		SIDER
42	Clonazepam	3777263	CTD
43	Clonidine	10852088 11929375	CTD
44	Clozapine	10085753	CTD
45	Cocaine	1527734 1570902 11812504	CTD
46	Colchicine	843157	CTD
47	Creatine	12394880	CTD
48	Cyclizine	17090261	CTD
49	Dexmedetomidine	20055202	CTD
50	Diazepam	View details 1306008 1391357 4569819 4807250 4973764 5440529 6476315 6928283 17940245 27641627	CTD
51	Diazoxide	2684032	CTD
52	Dichlorvos	15303389 17350689	CTD
53	Disulfiram	17414256	CTD
54	Droperidol	5817964 12460844	CTD
55	Enflurane	626424	CTD
56	Enkephalin, Ala(2)-MePhe(4)-Gly(5)-	19710394	CTD
57	Ephedrine	12394880	CTD
58	Epinephrine	3422794 8425252 9620513	CTD
59	Etorphine	4962749	CTD
60	Felbamate		SIDER
61	Fenoprofen	2321822	CTD
62	Fentanyl	View details 3257727 3337659 3938174 6110396 6129881 6784740 8986972 9037435 9698952 10475320 11581460 14694924 16764215 17914664 18544179 19461299 19755623 19819313 29669042	CTD SIDER
63	Flumazenil	1391357	CTD
64	Flupenthixol	6428599	CTD
65	Foscarnet		SIDER
66	Halothane	626424 8023596	CTD
67	Hydrocortisone	19078840	CTD
68	Hydromorphone	15098525	CTD
69	Hydroxychloroquine	7671986	CTD
70	Isoflurane	626424 2311153	CTD
71	Isoproterenol	5067981	CTD
72	Ketamine	8857811 15954974	CTD
73	Lamivudine	16029231	CTD
74	Levobupivacaine	12818949	CTD
75	Lidoderm	View details 64792 1530175 3422794 4051869 4931162 4968192 7274285 7614158 8425252 10475320 16563328	CTD
76	Lincomycin	1167742	CTD
77	M 140	9037435	CTD
78	Magnesium Sulfate	18441730 20864066	CTD
79	Maprotiline	6421394	CTD
80	Memantine		SIDER
81	Meperidine	283080 5440529 5528556	CTD
82	Methadone	View details 11145498 11744587 15278196 15454842 17968993 19819313	CTD
83	Methadyl Acetate	10215673	CTD
84	Methohexital	5115033 8768153	CTD
85	Methotrexate	3572937	CTD
86	Methoxyflurane	626424	CTD
87	Methyldopa	3364834	CTD
88	Methylprednisolone	2001080	CTD
89	Metoprolol	18566202	CTD
90	Midazolam	1608855 2920683 7747857	CTD SIDER
91	Minocycline	18706994	CTD
92	Morphine	View details 1305443 1833029 2208533 3136361 3377935 3515598 4025903 4462236 4962749 6262092 6662192 6894517 7023519 7832313 7848954 8869763 9168210 9620513 10475320 10764173 11180027 12065195 14534517 15954974 16971632 17961837 18706994 19462494 19755623 19819313 20802053 23300227	CTD SIDER
93	Mustard Gas	25331496	CTD
94	N-(cyclopropylmethyl)-19-isopentylnororvinol hydrochloride	4958020	CTD
95	Nalbuphine	3938174	CTD
96	Naloxone	View details 2311153 3136361 3377935 6110396 7711465 9037435 11145498 12065195 15278196 16764215 17330696 17968993 19755623	CTD
97	Neomycin	9669013	CTD
98	Nicardipine	8274062	CTD
99	Nicotine	1179485	CTD
100	Nitric Acid	19078840	CTD
101	Nitrofurantoin	19097002	CTD
102	Nitrous Oxide	2311153	CTD
103	Norepinephrine	11089775	CTD
104	Ofloxacin	16858118	CTD SIDER
105	Olanzapine	10085753	CTD
106	Oxygen	19078840	CTD
107	Pancuronium		SIDER
108	Papaverine	7847211	CTD
109	Paraquat	26099602	CTD
110	Pemetrexed		SIDER
111	Penicillamine	7425327	CTD
112	Pentazocine	3744788 5423846	CTD
113	Pentobarbital	1527734	CTD
114	Phenobarbital	4973764	CTD
115	Phenol	10465250	CTD
116	Phenylpropanolamine	709472	CTD
117	Physostigmine	7085965 14999367	CTD
118	Prasugrel Hydrochloride	19877380	CTD
119	Prednisolone	19078840	CTD
120	Prilocaine		SIDER
121	Procainamide	2842116	CTD
122	Promethazine	283080	CTD
123	Propofol	View details 7587272 7747857 9492929 11480255 15281502 16563328 16938600	CTD
124	Propranolol	909024	CTD
125	Propylthiouracil	1424898 16498810	CTD
126	Quinidine	7297261	CTD
127	Remifentanil	20461001	CTD
128	Rivastigmine		SIDER
129	Rocuronium		SIDER
130	Ropivacaine		SIDER
131	Sarin	26145887 27639427	CTD
132	Succinylcholine	5443962	CTD
133	Sufentanil	2311153 2932985 9249116	CTD
134	Tacrine	5443962	CTD
135	Terbutaline	8016770	CTD
136	Thiopental	5115033	CTD
137	Thioridazine	709472	CTD
138	Tramadol	6468480 9204095 27641627	CTD
139	Trazodone	8520792	CTD
140	Triazolam	2712085	CTD
141	Valproic Acid	6420146 8328579	CTD
142	Vancomycin	21148517	CTD
143	Vecuronium Bromide		SIDER
144	Vecuronium Bromide	2751916 7643872	CTD
145	Vincristine	5027400	CTD
146	amitraz	12046725 21288150	CTD
147	apraclonidine	17572343	CTD
148	argatroban		SIDER
149	azabicyclane	5528556	CTD
150	chloramphenicol succinate	4825630	CTD
151	chloroprocaine	18047629	CTD
152	iopromide		SIDER
153	liposomal amphotericin B		SIDER
154	naloxonazine	19819313	CTD
155	naltrindole	19819313	CTD
156	norbinaltorphimine	19819313	CTD
157	parecoxib		SIDER
158	phenyl biguanide	9696263	CTD
159	posatirelin	1305443 1833029	CTD
160	repinotan hydrochloride	20802053	CTD
161	ropinirole		SIDER
162	telavancin	21148517	CTD
163	thiosemicarbazide	2893236	CTD
164	trovafloxacin		SIDER
165	turmeric extract	29480285	CTD
166	valdecoxib		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Altitude Sickness	42.9%
2	Respiratory Distress Syndrome, Adult	38.1%
3	Vocal Cord Dysfunction	28.6%
4	Respiratory Aspiration	28.6%
5	Respiratory Distress Syndrome, Newborn	28.1%
6	Apnea	27.9%
7	Cheyne-Stokes Respiration	27.9%
8	Dyspnea	27.9%
9	Hyperventilation	27.9%
10	Mouth Breathing	27.9%
11	Tachypnea	27.9%
12	Bronchial Diseases	23.1%
13	Lung diseases	23.1%
14	Pleural Diseases	23.1%
15	Thoracic Diseases	23.1%
16	Tracheal Diseases	23.1%
17	Laryngospasm	20.3%
18	Alkalosis, Respiratory	20.2%
19	Sleep Apnea Syndromes	20.2%
20	Hyaline Membrane Disease	20.2%
21	Bronchitis	19.3%
22	Pleurisy	19%
23	Pneumonia	19%
24	Lobar Pneumonia	19%
25	Tracheitis	19%
26	Pneumonitis	19%
27	Meconium Aspiration Syndrome	17.4%
28	Bronchopneumonia	17.2%
29	Tracheobronchomegaly	16.9%
30	Sleep Apnea, Obstructive	16.6%
31	Sleep Apnea, Central	16.6%
32	Pleuropneumonia	16.2%
33	Laryngeal Diseases	15.8%
34	Nose Diseases	15.8%
35	Acute Chest Syndrome	15.3%
36	Asthma	15.2%
37	Dyspnea, Paroxysmal	15.1%
38	Respiratory Tract Infections	15%
39	Bronchitis, Chronic	14.7%
40	Granuloma, Respiratory Tract	14.6%
41	Respiratory Hypersensitivity	14.6%
42	Respiratory Tract Fistula	14.6%
43	Hoarseness	14.5%
44	Atelectasis	14.3%
45	Bronchospasm	14.3%
46	Bronchiectasis	14.3%
47	Bronchiolitis	14.3%
48	Chylothorax	14.3%
49	Hydropneumothorax	14.3%
50	Hydrothorax	14.3%
51	Pulmonary Hypertension	14.3%
52	Laryngitis	14.3%
53	Lung Diseases, Fungal	14.3%
54	Pneumothorax	14.3%
55	Pulmonary Alveolar Proteinosis	14.3%
56	Pulmonary Edema	14.3%
57	Pulmonary Fibrosis	14.3%
58	Rhinitis	14.3%
59	Tracheal Stenosis	14.3%
60	Bronchial Hyperreactivity	14.3%
61	Hamman-Rich syndrome	14.3%
62	Lung Diseases, Interstitial	14.3%
63	Lung Diseases, Obstructive	14.3%
64	Bronchial Fistula	13.9%
65	Lung Abscess	13.9%
66	Lung Neoplasms	13.9%
67	Pleural Neoplasms	13.9%
68	Tuberculosis, Pulmonary	13.8%
69	Aspiration Pneumonia	13.6%
70	Idiopathic Pulmonary Fibrosis	12.4%
71	Sinusitis	12.1%
72	Pleural Effusion, Malignant	12%
73	Bronchial Neoplasms	11.9%
74	Choanal Atresia	11.3%
75	Laryngocele	11.3%
76	Pneumonia, Lipid	11.1%
77	Tracheal Neoplasms	11%
78	Pneumoconiosis	10.7%
79	Pneumonia, Viral	10.7%
80	Aspergillosis, Allergic Bronchopulmonary	10.6%
81	Bronchiolitis Obliterans	10.5%
82	Pneumonia, Bacterial	10.3%
83	Epiglottitis	10.3%
84	Chronic Obstructive Airway Disease	10.3%
85	Mediastinitis	10.3%
86	Middle Lobe Syndrome	10.3%
87	Acute Lung Injury	10.3%
88	Asthma, Exercise-Induced	10%
89	Status Asthmaticus	10%
90	Multiple Pulmonary Nodules	10%
91	Granuloma, Lethal Midline	9.5%
92	Laryngeal Edema	9.5%
93	Nose Deformities, Acquired	9.5%
94	Lung Injury	9.5%
95	Hepatopulmonary Syndrome	9.5%
96	Laryngeal neoplasm	9.4%
97	Common Cold	9.3%
98	Hemothorax	9.3%
99	Influenza	9.3%
100	Catarrh	9.3%
101	Granuloma, Laryngeal	9.2%
102	Pulmonary Embolism	9.2%
103	Pulmonary Eosinophilia	9.1%
104	Severe Acute Respiratory Syndrome	9.1%
105	Eosinophilic Pneumonia	9.1%
106	Laryngopharyngeal Reflux	9.1%
107	Primary Ciliary Dyskinesia	8.8%
108	Asbestosis	8.5%
109	Berylliosis	8.5%
110	Pulmonary Emphysema	8.5%
111	Silicosis	8.5%
112	Asthma, Occupational	8.4%
113	Radiation Pneumonitis	8.2%
114	Radiation Fibrosis	8.2%
115	Scimitar Syndrome	7.9%
116	Paranasal Sinus Neoplasms	7.5%
117	Farmer's Lung	7.4%
118	Hay fever	7.3%
119	Rhinitis, Allergic, Perennial	7.3%
120	Pharyngitis	7.1%
121	Laryngostenosis	7%
122	Nasal Polyps	7%
123	Mediastinal Cyst	7%
124	Pericardial Cyst	7%
125	Persistent Fetal Circulation Syndrome	7%
126	Thymic Cyst	7%
127	Hemoptysis	6.9%
128	Nose Neoplasms	6.9%
129	Pertussis	6.8%
130	Croup	6.8%
131	Histiocytosis, Langerhans-Cell	6.8%
132	Mediastinal Emphysema	6.8%
133	Rhinitis, Vasomotor	6.8%
134	Pulmonary Aspergillosis	6.8%
135	Bronchopulmonary Aspergillosis	6.8%
136	Rhinoscleroma	6.8%
137	Sarcoidosis, Pulmonary	6.7%
138	Asthma, Aspirin-Induced	6.7%
139	Pulmonary Infarction	6.7%
140	Maxillary Sinus Neoplasms	6.1%
141	Blastomycosis	5.7%
142	Cystic Fibrosis	5.7%
143	Kartagener Syndrome	5.7%
144	Voice Disorders	5.6%
145	Voice Disturbance	5.6%
146	Bronchopulmonary Dysplasia	5.6%
147	Epistaxis	5.6%
148	Tonsillitis	5.1%
149	Granulomatosis with polyangiitis	5%
150	Laryngomalacia	4.7%
151	Vocal Cord Paralysis	4.6%
152	Transfusion-Related Acute Lung Injury	4.3%
153	Invasive Pulmonary Aspergillosis	4.2%
154	Aphonia	4%
155	Retropharyngeal Abscess	4%
156	Dysphonia	4%
157	Anti-Glomerular Basement Membrane Disease	4%
158	Bronchomalacia	4%
159	Tracheomalacia	4%
160	Nasopharyngitis	3.4%
161	Peritonsillar Abscess	3.3%
162	Eosinophilic Granuloma	2.8%

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