MetaADEDB 2.0 @ LMMD
Diazoxide
(GDLBFKVLRPITMI-UHFFFAOYSA-N)
Structure
SMILES
Clc1ccc2c(c1)S(=O)(=O)N=C(N2)C
Type(s)
Approved
ATC code(s)
C02DA01; G01AE10; V03AH01
Molecular Formula:
C8H7ClN2O2S
Molecular Weight:
230.671
Log P:
2.5270
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
66.91
CAS Number(s):
364-98-7
Synonym(s)
1.
Diazoxide
2.
Hyperstat
3.
Proglycem
External Link(s)
MeSHD003981
PubChem Compound3019
BindingDB86248
50237612
50241108
ChEBI4495
CHEMBLCHEMBL1518123
CHEMBL181
DrugBankDB01119
DrugCentral854
IUPHAR/BPS Guide to PHARMACOLOGY2409
KEGGcpd:C06949
dr:D00294
Therapeutic Target DatabaseD07WEP
ZINC3872277
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pulmonary HypertensionFAERS: 10
Canada Vigilance: 4		Canada Vigilance
US FAERS
2Drug ineffectiveFAERS: 7US FAERS
3Blood glucose decreasedFAERS: 4US FAERS
4HypertrichosisFAERS: 42040926CTD
US FAERS
5PancytopeniaFAERS: 4US FAERS
6Patent ductus arteriosusFAERS: 4US FAERS
7Respiratory FailureFAERS: 4US FAERS
8TachycardiaFAERS: 4962230
3675083
4387262		CTD
SIDER
US FAERS
9Bone marrow depressionFAERS: 3US FAERS
10ChillsFAERS: 3US FAERS
11Feeling abnormalFAERS: 3SIDER
US FAERS
12GastroenteritisFAERS: 3US FAERS
13NasopharyngitisFAERS: 3US FAERS
14NeutropeniaFAERS: 318512033
20857844		CTD
US FAERS
15Neutrophil count decreasedFAERS: 3US FAERS
16Alanine Aminotransferase IncreasedFAERS: 2US FAERS
17Aspartate Aminotransferase IncreasedFAERS: 2SIDER
US FAERS
18EczemaFAERS: 2US FAERS
19EpilepsyFAERS: 2US FAERS
20Gastric hypermotilityFAERS: 2US FAERS
21General physical health deteriorationFAERS: 2US FAERS
22HeadacheFAERS: 2SIDER
US FAERS
23HirsutismFAERS: 24299224CTD
SIDER
US FAERS
24HyperchlorhydriaFAERS: 2US FAERS
25HypothyroidismFAERS: 2US FAERS
26Insulin C-peptide increasedFAERS: 2US FAERS
27LymphadenopathyFAERS: 2SIDER
US FAERS
28Meconium ileusFAERS: 2US FAERS
29NauseaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
30Pulmonary arterial hypertensionFAERS: 2US FAERS
31PurpuraFAERS: 2SIDER
US FAERS
32Respiratory distressFAERS: 2US FAERS
33SepsisFAERS: 2US FAERS
34ShockFAERS: 2US FAERS
35SubileusFAERS: 2US FAERS
36TremorFAERS: 2US FAERS
37Adverse eventFAERS: 1US FAERS
38AlopeciaFAERS: 1US FAERS
39Amylase decreasedFAERS: 1US FAERS
40AnxietyFAERS: 1SIDER
US FAERS
41BicytopeniaFAERS: 1US FAERS
42Blood glucose increasedFAERS: 1US FAERS
43CardiomegalyFAERS: 14387262
27867086		CTD
US FAERS
44Chest discomfortFAERS: 1US FAERS
45CholelithiasisFAERS: 1US FAERS
46CholestasisFAERS: 1US FAERS
47Depressed Level of ConsciousnessFAERS: 1US FAERS
48Disease ProgressionFAERS: 1US FAERS
49Drug toxicityFAERS: 1US FAERS
50DysgeusiaFAERS: 1US FAERS
51Echocardiogram abnormalFAERS: 1US FAERS
52FatigueFAERS: 1US FAERS
53HyperinsulinismFAERS: 12040926
3970573
17937066		CTD
US FAERS
54HypotensionFAERS: 1

View details

946045
1015921
2201220
3675083
4740489
7253756
10796261
11171655
12519557
 		CTD
SIDER
US FAERS
55HypoxiaFAERS: 1US FAERS
56InfectionFAERS: 1US FAERS
57KetosisFAERS: 1US FAERS
58LaryngomalaciaFAERS: 117937066CTD
US FAERS
59LeukopeniaFAERS: 1SIDER
US FAERS
60Lipase increasedFAERS: 1US FAERS
61Lung cystFAERS: 1US FAERS
62MalaiseFAERS: 1SIDER
US FAERS
63Metastatic NeoplasmFAERS: 1US FAERS
64Musculoskeletal chest painFAERS: 1US FAERS
65Pancreatic NeoplasmFAERS: 1US FAERS
66Pericardial effusionFAERS: 1US FAERS
67PneumoniaFAERS: 1US FAERS
68PneumothoraxFAERS: 1US FAERS
69Product quality issueFAERS: 1US FAERS
70Pulmonary arteriopathyFAERS: 1US FAERS
71Respiratory DepressionFAERS: 1US FAERS
72Right Ventricular HypertrophyFAERS: 1US FAERS
73Sodium retentionFAERS: 1US FAERS
74ThrombocytopeniaFAERS: 1SIDER
US FAERS
75Upper respiratory tract inflammationFAERS: 1US FAERS
76Urinary tract infectionFAERS: 1US FAERS
77VasculitisFAERS: 1US FAERS
78VomitingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
79Abdominal PainSIDER
80Abdominal discomfortSIDER
81Acute kidney injury5738352CTD
82AgeusiaSIDER
83AlbuminuriaSIDER
84Anemia20857844CTD
85Angina Pectoris937881
946045
962230		CTD
86AnorexiaSIDER
87Apnea17937066CTD
88AstheniaSIDER
89Ataxia3970573CTD
90Atrioventricular Block7295436CTD
91Azotemia5738352CTD
92Blindness90906CTD
93Blood creatinine decreasedSIDER
94Blood immunoglobulin G decreasedSIDER
95Bradycardia3675083CTD
96Brain Ischemia946045
6409644		CTD
97CataractSIDER
98Chest PainSIDER
99Congenital Hyperinsulinism2684032
10923237		CTD
100Creatinine lowSIDER
101DermatitisSIDER
102Diabetes Mellitus1445173CTD
103Diabetic KetoacidosisSIDER
104DiplopiaSIDER
105DiscomfortSIDER
106DizzinessCanada Vigilance: 1Canada Vigilance
SIDER
107DysarthriaCanada Vigilance: 1Canada Vigilance
108Eclampsia4532529CTD
109Edema4299224CTD
110Emotional distressSIDER
111EosinophiliaSIDER
112Exanthema4299224CTD
113Fluid overloadCanada Vigilance: 1Canada Vigilance
114FlushingSIDER
115Gastrointestinal PainSIDER
116Gingival Hypertrophy2040926CTD
117Glycogen Storage Disease4299224CTD
118GlycosuriaSIDER
119GoutSIDER
120Heart Block5015079CTD
121Heart failure2684032
3970573
18512033		CTD
122Hemiplegia946045CTD
123Herpes NOSSIDER
124Hyperalgesia15063156CTD
125Hyperglycemia4299224
4875711
5086767		CTD
126Hyperglycemic Hyperosmolar Nonketotic Coma5544160CTD
127HypersensitivitySIDER
128Hyperuricemia4299224CTD
129Hypoglycemia, leucine-induced4299224
6510895		CTD
130Hypoglycemia

View details

2040926
3970573
4299224
4387262
5544160
 		CTD
131IleusSIDER
132Immunoglobulin G lowSIDER
133KetoacidosisSIDER
134LacrimationSIDER
135LightheadednessSIDER
136Motor Disorders18700057CTD
137Movement Disorders1114967
4726153		CTD
138Myocardial Infarction835911
946045		CTD
139Myocardial Ischemia937881CTD
140Necrosis21983523CTD
141Nephrotic SyndromeSIDER
142Nerve Degeneration18700057
21256120		CTD
143Nesidioblastosis3970573CTD
144Pain18210232CTD
SIDER
145PalpitationsSIDER
146PancreatectomyCanada Vigilance: 1Canada Vigilance
147PancreatitisSIDER
148Parkinsonian Disorders15795934
15927086		CTD
149PolyneuritisSIDER
150PolyneuropathySIDER
151Preeclamptic toxemia4532529CTD
152PruritusSIDER
153Reperfusion Injury12409977CTD
154Respiratory Insufficiency2684032CTD
155ScotomaSIDER
156Sensation of warmthSIDER
157SomnolenceCanada Vigilance: 1Canada Vigilance
158Subconjunctival hemorrhageSIDER
159SweatingSIDER
160Vascular purpuraSIDER
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