MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Mediastinitis

(UMLS:C0025064)

Definition:: Inflammation of the mediastinum, the area between the pleural sacs.
UMLS ID:: C0025064
MeSH ID:: D008480

Classification:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.846.187.790

Synonym(s)

Mediastinitis

Inflammatory disorder of mediastinum

MEDIASTINITIS

mediastinitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ketoprofen	FAERS: 3		US FAERS
2	Tacrolimus	FAERS: 3		US FAERS
3	Clozapine	FAERS: 2		US FAERS
4	Daptomycin	FAERS: 2		US FAERS
5	Micafungin	FAERS: 2		US FAERS
6	Morphine	FAERS: 2		US FAERS
7	Nitroglycerin	FAERS: 2		US FAERS
8	Paclitaxel	FAERS: 2		US FAERS
9	Triamcinolone	FAERS: 2		US FAERS
10	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
11	Alendronate	FAERS: 1		US FAERS
12	Axitinib	FAERS: 1		US FAERS
13	Ciprofloxacin	FAERS: 1		US FAERS
14	Cyclosporine	FAERS: 1		US FAERS
15	Erlotinib Hydrochloride	FAERS: 1		OFFSIDES US FAERS
16	Hydromorphone	FAERS: 1		US FAERS
17	Imatinib Mesylate	FAERS: 1		US FAERS
18	Leflunomide	FAERS: 1		US FAERS
19	Linezolid	FAERS: 1		US FAERS
20	Omeprazole	FAERS: 1		US FAERS
21	Valsartan	FAERS: 1		US FAERS
22	Zoledronic Acid	FAERS: 1		US FAERS
23	ambrisentan	FAERS: 1		US FAERS
24	bivalirudin	FAERS: 1		US FAERS
25	lenvatinib	FAERS: 1		US FAERS
26	rofecoxib	FAERS: 1		US FAERS
27	Aluminum Hydroxide			OFFSIDES
28	Amphetamine			OFFSIDES
29	Aztreonam			OFFSIDES
30	Carboplatin			OFFSIDES
31	Cefotiam			OFFSIDES
32	Chlorpheniramine			OFFSIDES
33	Clomiphene			OFFSIDES
34	Clopidogrel			OFFSIDES
35	Clotrimazole			OFFSIDES
36	Daptomycin			SIDER
37	Dexmedetomidine			OFFSIDES
38	Dextromethorphan			OFFSIDES
39	Dihematoporphyrin Ether			OFFSIDES
40	Dipyrone			OFFSIDES
41	Domperidone			OFFSIDES
42	Doripenem			OFFSIDES
43	Epinephrine			OFFSIDES
44	Eplerenone			OFFSIDES
45	Erlotinib Hydrochloride			OFFSIDES
46	Fenofibrate			OFFSIDES
47	Fondaparinux			OFFSIDES
48	Fosinopril			OFFSIDES
49	Fusidic Acid			OFFSIDES
50	Gatifloxacin			OFFSIDES
51	Glutamine			OFFSIDES
52	Hydrocortisone			OFFSIDES
53	Hydrocortisone sodium succinate			OFFSIDES
54	Itraconazole			OFFSIDES
55	Medroxyprogesterone Acetate			OFFSIDES
56	Medroxyprogesterone			OFFSIDES
57	Meperidine			OFFSIDES
58	Metolazone			OFFSIDES
59	Milrinone			OFFSIDES
60	Nabumetone			OFFSIDES
61	Neomycin		5548981	CTD
62	Netilmicin		711647	CTD
63	Norepinephrine			OFFSIDES
64	Olopatadine Hydrochloride			OFFSIDES
65	Orlistat			OFFSIDES
66	Oxacillin			OFFSIDES
67	Pemetrexed			OFFSIDES
68	Prednisone acetate			OFFSIDES
69	Quetiapine Fumarate			OFFSIDES
70	Sirolimus			OFFSIDES
71	Sitagliptin Phosphate			OFFSIDES
72	Vitamin B 12			OFFSIDES
73	camostat			OFFSIDES
74	nedaplatin			OFFSIDES
75	sibutramine			OFFSIDES
76	valdecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Mediastinal Cyst	31.8%
2	Pericardial Cyst	31.8%
3	Thymic Cyst	31.8%
4	Mediastinal Emphysema	31.1%
5	Bronchial Diseases	18.5%
6	Lung diseases	18.5%
7	Pleural Diseases	18.5%
8	Respiration Disorders	18.5%
9	Tracheal Diseases	18.5%
10	Pleurisy	14%
11	Pneumonia	14%
12	Lobar Pneumonia	14%
13	Respiratory Distress Syndrome, Adult	14%
14	Tracheitis	14%
15	Pneumonitis	14%
16	Bronchitis	13.8%
17	Laryngeal Diseases	12.8%
18	Nose Diseases	12.8%
19	Tracheobronchomegaly	12.5%
20	Respiratory Tract Infections	12.2%
21	Granuloma, Respiratory Tract	11.9%
22	Respiratory Hypersensitivity	11.9%
23	Respiratory Tract Fistula	11.9%
24	Bronchopneumonia	11.9%
25	Asthma	10.9%
26	Pleuropneumonia	10.7%
27	Laryngitis	10.5%
28	Lung Diseases, Fungal	10.5%
29	Rhinitis	10.5%
30	Vocal Cord Dysfunction	10.5%
31	Altitude Sickness	10.3%
32	Atelectasis	10.3%
33	Bronchospasm	10.3%
34	Bronchiectasis	10.3%
35	Chylothorax	10.3%
36	Hydropneumothorax	10.3%
37	Hydrothorax	10.3%
38	Pulmonary Hypertension	10.3%
39	Pneumothorax	10.3%
40	Pulmonary Alveolar Proteinosis	10.3%
41	Pulmonary Edema	10.3%
42	Pulmonary Fibrosis	10.3%
43	Respiratory Distress Syndrome, Newborn	10.3%
44	Respiratory Insufficiency	10.3%
45	Tracheal Stenosis	10.3%
46	Bronchial Hyperreactivity	10.3%
47	Hamman-Rich syndrome	10.3%
48	Lung Diseases, Interstitial	10.3%
49	Respiratory Depression	10.3%
50	Lung Diseases, Obstructive	10.3%
51	Respiratory Failure	10.3%
52	Bronchial Fistula	10.3%
53	Lung Abscess	10.3%
54	Lung Neoplasms	10.3%
55	Pleural Neoplasms	10.3%
56	Tuberculosis, Pulmonary	10.2%
57	Bronchitis, Chronic	9.2%
58	Granuloma, Laryngeal	9.1%
59	Bronchiolitis	9.1%
60	Aspiration Pneumonia	8.9%
61	Sinusitis	8.5%
62	Bronchial Neoplasms	8.4%
63	Choanal Atresia	8.3%
64	Laryngocele	8.3%
65	Tracheal Neoplasms	8.2%
66	Pleural Effusion, Malignant	7.9%
67	Idiopathic Pulmonary Fibrosis	7.7%
68	Primary Ciliary Dyskinesia	7.2%
69	Aspergillosis, Allergic Bronchopulmonary	7.2%
70	Pneumoconiosis	7%
71	Pneumonia, Viral	7%
72	Granuloma, Lethal Midline	7%
73	Laryngeal Edema	7%
74	Nose Deformities, Acquired	7%
75	Lung Injury	7%
76	Hepatopulmonary Syndrome	7%
77	Respiratory Aspiration	7%
78	Laryngeal neoplasm	6.9%
79	Apnea	6.8%
80	Cheyne-Stokes Respiration	6.8%
81	Common Cold	6.8%
82	Dyspnea	6.8%
83	Hemothorax	6.8%
84	Hyperventilation	6.8%
85	Influenza	6.8%
86	Mouth Breathing	6.8%
87	Tachypnea	6.8%
88	Catarrh	6.8%
89	Pneumonia, Bacterial	6.8%
90	Pulmonary Embolism	6.7%
91	Pulmonary Eosinophilia	6.7%
92	Severe Acute Respiratory Syndrome	6.7%
93	Eosinophilic Pneumonia	6.7%
94	Laryngopharyngeal Reflux	6.7%
95	Airway Obstruction	6.7%
96	Choking	6.7%
97	Epiglottitis	6.7%
98	Laryngospasm	6.7%
99	Chronic Obstructive Airway Disease	6.7%
100	Middle Lobe Syndrome	6.7%
101	Acute Lung Injury	6.7%
102	Hyaline Membrane Disease	6.6%
103	Asthma, Exercise-Induced	6.6%
104	Status Asthmaticus	6.6%
105	Multiple Pulmonary Nodules	6.6%
106	Pneumonia, Lipid	6.5%
107	Bronchiolitis Obliterans	5.9%
108	Scimitar Syndrome	5.9%
109	Meconium Aspiration Syndrome	5.7%
110	Acute Chest Syndrome	5.7%
111	Asthma, Occupational	5.5%
112	Radiation Pneumonitis	5.4%
113	Radiation Fibrosis	5.4%
114	Pharyngitis	5.3%
115	Laryngostenosis	5.2%
116	Nasal Polyps	5.2%
117	Nose Neoplasms	5.1%
118	Hemoptysis	5.1%
119	Rhinoscleroma	5.1%
120	Pertussis	5%
121	Asbestosis	5%
122	Berylliosis	5%
123	Silicosis	5%
124	Paranasal Sinus Neoplasms	5%
125	Pulmonary Emphysema	4.9%
126	Hoarseness	4.8%
127	Farmer's Lung	4.7%
128	Hay fever	4.6%
129	Rhinitis, Allergic, Perennial	4.6%
130	Persistent Fetal Circulation Syndrome	4.5%
131	Croup	4.4%
132	Histiocytosis, Langerhans-Cell	4.4%
133	Rhinitis, Vasomotor	4.4%
134	Asthma, Aspirin-Induced	4.4%
135	Pulmonary Aspergillosis	4.4%
136	Bronchopulmonary Aspergillosis	4.4%
137	Hypoventilation	4.4%
138	Acidosis, Respiratory	4.4%
139	Alkalosis, Respiratory	4.4%
140	Sarcoidosis, Pulmonary	4.4%
141	Sleep Apnea Syndromes	4.4%
142	Pulmonary Infarction	4.4%
143	Cystic Fibrosis	4.2%
144	Voice Disorders	4.2%
145	Voice Disturbance	4.2%
146	Kartagener Syndrome	4.1%
147	Epistaxis	4.1%
148	Blastomycosis	3.8%
149	Maxillary Sinus Neoplasms	3.6%
150	Laryngomalacia	3.4%
151	Vocal Cord Paralysis	3.4%
152	Tonsillitis	3.3%
153	Dyspnea, Paroxysmal	3.3%
154	Respiratory Paralysis	3.3%
155	Bronchopulmonary Dysplasia	3.3%
156	Granulomatosis with polyangiitis	3.3%
157	Sleep Apnea, Obstructive	3.2%
158	Sleep Apnea, Central	3.2%
159	Aphonia	2.6%
160	Retropharyngeal Abscess	2.6%
161	Dysphonia	2.6%
162	Anti-Glomerular Basement Membrane Disease	2.6%
163	Bronchomalacia	2.6%
164	Tracheomalacia	2.6%
165	Transfusion-Related Acute Lung Injury	2.5%
166	Invasive Pulmonary Aspergillosis	2.5%
167	Nasopharyngitis	2.2%
168	Peritonsillar Abscess	1.9%
169	Eosinophilic Granuloma	1.7%

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