MetaADEDB 2.0 @ LMMD
Mannitol
(FBPFZTCFMRRESA-KVTDHHQDSA-N)
Structure
SMILES
OC[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
Type(s)
Approved; Investigational
ATC code(s)
A06AD16; B05BC01; B05CX04; R05CB16
Molecular Formula:
C6H14O6
Molecular Weight:
182.172
Log P:
-3.5854
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
6
TPSA:
121.38
CAS Number(s):
69-65-8; 87-78-5
Synonym(s)
1.
Mannitol
2.
(L)-Mannitol
3.
Osmitrol
4.
Osmofundin
External Link(s)
MeSHD008353
PubChem Compound6251
BindingDB50142798
ChEBI16899
CHEMBLCHEMBL689
DrugBankDB00742
DrugCentral935
KEGGcpd:C00392
dr:D00062
Therapeutic Target DatabaseD0P7EK
ZINC2041302
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Toxicity to various agentsFAERS: 10US FAERS
2ChillsFAERS: 9
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
3HeadacheFAERS: 6SIDER
US FAERS
4Blood glucose increasedFAERS: 4US FAERS
5Cardiac ArrestFAERS: 4US FAERS
6Fluid overloadFAERS: 4OFFSIDES
SIDER
US FAERS
7HypotensionFAERS: 4

View details

32802
571222
10067030
16671420
 		CTD
SIDER
US FAERS
8LethargyFAERS: 4US FAERS
9NauseaFAERS: 4OFFSIDES
SIDER
US FAERS
10Anaphylactoid ReactionFAERS: 3US FAERS
11Medication ErrorFAERS: 3US FAERS
12Product label confusionFAERS: 3US FAERS
13Wrong drug administeredFAERS: 3US FAERS
14AsthmaFAERS: 2OFFSIDES
US FAERS
15Chest PainFAERS: 2OFFSIDES
SIDER
US FAERS
16DizzinessFAERS: 2SIDER
US FAERS
17Ear discomfortFAERS: 2US FAERS
18ExtravasationFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
19Incorrect dose administeredFAERS: 2US FAERS
20Product use in unapproved indicationFAERS: 2US FAERS
21Abdominal discomfortFAERS: 1OFFSIDES
US FAERS
22AmnesiaFAERS: 1US FAERS
23AstheniaFAERS: 1OFFSIDES
SIDER
US FAERS
24Blood osmolarity increasedFAERS: 1US FAERS
25Blood pH decreasedFAERS: 1US FAERS
26Blood pH increasedFAERS: 1US FAERS
27Bronchial HyperreactivityFAERS: 1US FAERS
28Catheter site swellingFAERS: 1US FAERS
29Chest discomfortFAERS: 1SIDER
US FAERS
30Choking sensationFAERS: 1OFFSIDES
US FAERS
31CyanosisFAERS: 1OFFSIDES
US FAERS
32DeafnessFAERS: 1US FAERS
33Depressed Level of ConsciousnessFAERS: 1OFFSIDES
US FAERS
34Disease ProgressionFAERS: 1US FAERS
35DiverticulitisFAERS: 1US FAERS
36Drug administration errorFAERS: 1US FAERS
37Drug dose omissionFAERS: 1US FAERS
38Drug ineffectiveFAERS: 1US FAERS
39Drug monitoring procedure not performedFAERS: 1US FAERS
40Electrolyte imbalanceFAERS: 1SIDER
US FAERS
41ErythemaFAERS: 1US FAERS
42GangreneFAERS: 1US FAERS
43Hyperosmolar stateFAERS: 1OFFSIDES
US FAERS
44HyperpyrexiaFAERS: 1US FAERS
45Infusion Site ExtravasationFAERS: 1US FAERS
46Intercepted drug administration errorFAERS: 1US FAERS
47Large intestine perforationFAERS: 1OFFSIDES
US FAERS
48Medication monitoring errorFAERS: 1US FAERS
49Mental status changesFAERS: 1OFFSIDES
US FAERS
50Metabolic acidosisFAERS: 1OFFSIDES
US FAERS
51Nephrotic SyndromeFAERS: 1SIDER
US FAERS
52Osmolar gap abnormalFAERS: 1US FAERS
53OverdoseFAERS: 1US FAERS
54PainFAERS: 1OFFSIDES
SIDER
US FAERS
55Peripheral swellingFAERS: 1US FAERS
56Pharmaceutical product complaintFAERS: 1US FAERS
57PolyuriaFAERS: 1SIDER
US FAERS
58Poor peripheral circulationFAERS: 1US FAERS
59Poor quality drug administeredFAERS: 1US FAERS
60Product closure issueFAERS: 1US FAERS
61Product depositFAERS: 1US FAERS
62Product label issueFAERS: 1US FAERS
63Product packaging confusionFAERS: 1US FAERS
64Product quality issueFAERS: 1US FAERS
65Product use issueFAERS: 1US FAERS
66Rash erythematousFAERS: 1US FAERS
67RhinitisFAERS: 1OFFSIDES
SIDER
US FAERS
68SepsisFAERS: 1US FAERS
69SwellingFAERS: 1US FAERS
70Therapy cessationFAERS: 1US FAERS
71TremorFAERS: 1US FAERS
72Urinary RetentionFAERS: 1SIDER
US FAERS
73Ventricular FibrillationFAERS: 12745010CTD
OFFSIDES
US FAERS
74VomitingFAERS: 1SIDER
US FAERS
75AIDS related complicationOFFSIDES
76Abdominal PainOFFSIDES
77Abnormal visionOFFSIDES
78AcidosisOFFSIDES
SIDER
79AcneSIDER
80Acute Lung Injury21748612CTD
81Acute kidney injury

View details

513486
691972
735158
1751788
2111870
2500855
2513521
3015452
3086006
3106845
5695673
6435559
6437357
6769339
7724007
7734574
7900744
7991027
8184141
8379473
8431614
8529299
8856292
9038039
9189872
9590800
11247599
12381962
14599652
16235675
18093429
20118599
20557870
24778426
 		CTD
82Acute myocardial infarctionOFFSIDES
83AdenitisOFFSIDES
84Adrenal atrophyOFFSIDES
85AgnosiaOFFSIDES
86AgraphiaOFFSIDES
87Alanine Aminotransferase IncreasedOFFSIDES
88Alcohol poisoningOFFSIDES
89Altered state of consciousnessOFFSIDES
90AlveolitisOFFSIDES
91Angina PectorisSIDER
92AngiodysplasiaOFFSIDES
93AnhedoniaOFFSIDES
94AnisocoriaOFFSIDES
95AnorexiaOFFSIDES
96Anticholinergic SyndromeOFFSIDES
97AnxietyOFFSIDES
98ArthralgiaSIDER
99ArthritisOFFSIDES
100ArthropathyOFFSIDES
101Aspartate aminotransferase abnormalOFFSIDES
102Aspiration PneumoniaOFFSIDES
103AtaxiaOFFSIDES
104AtelectasisOFFSIDES
105AtherosclerosisOFFSIDES
106Atrial tachycardiaOFFSIDES
107Atrial thrombosisOFFSIDES
108Autonomic neuropathyOFFSIDES
109Azotemia5087393CTD
110Back PainSIDER
111Bacterial disease carrierSIDER
112Band neutrophil percentage increasedOFFSIDES
113Beta 2 microglobulin increasedOFFSIDES
114Bilirubin conjugated increasedOFFSIDES
115Blood GlucoseOFFSIDES
116Blood albumin abnormalOFFSIDES
117Blood albumin decreasedOFFSIDES
118Blood albuminOFFSIDES
119Blood alkaline phosphatase decreasedOFFSIDES
120Blood alkaline phosphatase increasedSIDER
121Blood alkaline phosphataseOFFSIDES
122Blood cholesterolOFFSIDES
123Blood creatine phosphokinase MB increasedOFFSIDES
124Blood creatine phosphokinase increasedOFFSIDES
125Blood creatinine increasedOFFSIDES
126Blood fibrinogen increasedOFFSIDES
127Blood lactate dehydrogenase increasedOFFSIDES
128Blood magnesium decreasedOFFSIDES
129Blood magnesium increasedOFFSIDES
130Blood phosphorus decreasedOFFSIDES
131Blood phosphorusOFFSIDES
132Blood potassium decreasedOFFSIDES
133Blood sodium increasedOFFSIDES
134Blood sodiumOFFSIDES
135Blood thyroid stimulating hormone increasedOFFSIDES
136Blood urea increasedOFFSIDES
137Blood uric acidOFFSIDES
138Body TemperatureOFFSIDES
139BradycardiaOFFSIDES
140Brain DeathOFFSIDES
141Brain Edema

View details

8184141
8630150
10742073
15519365
17019386
 		CTD
142Brain Ischemia6799378CTD
143BronchitisOFFSIDES
SIDER
144Bronchoalveolar LavageOFFSIDES
145BronchopneumoniaOFFSIDES
SIDER
146BronchospasmCanada Vigilance: 1Canada Vigilance
SIDER
147Bulbar palsyOFFSIDES
148BursitisOFFSIDES
149Butterfly rashOFFSIDES
150Cancer PainOFFSIDES
151Candida pneumoniaOFFSIDES
152Cardiac ventricular disorderOFFSIDES
153Cardioactive drug level increasedOFFSIDES
154CataractOFFSIDES
155Cerebral Hemorrhage6411871
11897545
12691796		CTD
156Cerebral PalsyOFFSIDES
157Cerebral atrophyOFFSIDES
158Cerebral ventricle dilatationOFFSIDES
159Cervical dysplasiaOFFSIDES
160Cervical laser therapyOFFSIDES
161Cervical myelopathyOFFSIDES
162CholecystitisOFFSIDES
163Chronic Obstructive Airway DiseaseOFFSIDES
164Chronic respiratory failureOFFSIDES
165Clostridium colitisOFFSIDES
166Cold sweatSIDER
167Compartment syndromes15462158
17335600		CTD
168Complex partial seizuresOFFSIDES
169Complications of maternal exposure to therapeutic drugsOFFSIDES
170Compulsive sexual behaviourOFFSIDES
171ConfabulationOFFSIDES
172Congenital pyelocaliectasisOFFSIDES
173Craniocerebral Trauma3151702
10067030		CTD
174Croup infectiousOFFSIDES
175Cytomegalovirus chorioretinitisOFFSIDES
176DehydrationOFFSIDES
SIDER
177DemyelinationOFFSIDES
178Dental cariesOFFSIDES
179Denture wearerOFFSIDES
180DermatitisSIDER
181Device related infectionOFFSIDES
182Diabetes MellitusSIDER
183Diabetes mellitus inadequate controlOFFSIDES
184Diabetic NephropathyOFFSIDES
185DiarrheaOFFSIDES
186Dihydropyrimidine Dehydrogenase DeficiencyOFFSIDES
187DiscomfortSIDER
188Disseminated Intravascular CoagulationOFFSIDES
189DiuresisSIDER
190Diverticular perforationOFFSIDES
191DiverticulosisOFFSIDES
192DiverticulumOFFSIDES
193Drug Eruptions11792017CTD
194Dry skinOFFSIDES
195DysphasiaOFFSIDES
196DysphoniaSIDER
197Ear and labyrinth disordersSIDER
198Economic problemOFFSIDES
199Edema14718644CTD
200Electrocardiogram ST-T changeOFFSIDES
201Electrocardiogram ST-T segment abnormalOFFSIDES
202EmbolismOFFSIDES
203Emotional disorderOFFSIDES
204Emotional distressOFFSIDES
205Encephalitis6424993CTD
206EndocarditisOFFSIDES
207Enterobacter pneumoniaOFFSIDES
208Enterococcal infectionOFFSIDES
209Enterocutaneous FistulaOFFSIDES
210Erosive gastritisOFFSIDES
211EructationSIDER
212Escherichia infectionOFFSIDES
213Escherichia urinary tract infectionOFFSIDES
214Extremity necrosisOFFSIDES
215FatigueOFFSIDES
SIDER
216Febrile NeutropeniaOFFSIDES
217Febrile bone marrow aplasiaOFFSIDES
218Feeling abnormalSIDER
219Feeling jitterySIDER
220Fibrin increasedOFFSIDES
221Fistula dischargeOFFSIDES
222FlatulenceSIDER
223Fluid and electrolyte imbalanceSIDER
224FolliculitisOFFSIDES
225Foreign body traumaOFFSIDES
226Fungal rashOFFSIDES
227Fungal test positiveSIDER
228Fungus sputum test positiveSIDER
229GaggingSIDER
230Gastric ulcerOFFSIDES
231GastroenteritisOFFSIDES
232Gastrointestinal toxicityOFFSIDES
233General physical health deteriorationOFFSIDES
234Glaucoma3106845CTD
235Glioma17019386CTD
236Graft infectionOFFSIDES
237GranulocytosisOFFSIDES
238HaematotoxicityOFFSIDES
239Hearing Loss9223576CTD
240Heart Diseases8184141CTD
241HemiparesisOFFSIDES
242HemiplegiaOFFSIDES
243Heparin-induced thrombocytopeniaOFFSIDES
244Hepatitis11182525CTD
245Hernia painSIDER
246HiccoughOFFSIDES
247HydrocephalusOFFSIDES
248HydronephrosisOFFSIDES
249HypercapniaOFFSIDES
250Hypernatremia20804114CTD
251HypersensitivitySIDER
252Hypertrophic CardiomyopathyOFFSIDES
253HyperventilationSIDER
254Hypokalemia20804114CTD
255Hyponatremia3919450
17333050
20804114		CTD
256HypoxiaSIDER
257Immunosuppressant drug levelOFFSIDES
258Incision site infectionOFFSIDES
259IncoherentOFFSIDES
260Infection in an immunocompromised hostOFFSIDES
261InfectionSIDER
262Infective exacerbation of chronic obstructive airways diseaseOFFSIDES
263InfestationSIDER
264InflammationCanada Vigilance: 1Canada Vigilance
265Infusion site mobility decreasedOFFSIDES
266Initial insomniaSIDER
267Injection Site ReactionCanada Vigilance: 1Canada Vigilance
268Injection site infectionOFFSIDES
269Injection site inflammationOFFSIDES
270Injury asphyxiationOFFSIDES
271Intervertebral Disc DegenerationOFFSIDES
272Intestinal ObstructionOFFSIDES
273Intestinal PerforationOFFSIDES
274Intracranial AneurysmOFFSIDES
275Intracranial Hypertension

View details

2111870
3151702
6437357
8379473
15829166
16302998
17019386
 		CTD
276Joint Range of Motion DecreasedOFFSIDES
277Joint stiffnessOFFSIDES
SIDER
278Karnofsky scale worsenedOFFSIDES
279Kidney Diseases

View details

1436300
5082364
6785722
10399635
19535188
 		CTD
280Kidney FailureOFFSIDES
281LaryngomalaciaOFFSIDES
282Left Ventricular HypertrophyOFFSIDES
283Leukopenia neonatalOFFSIDES
284Lip erosionOFFSIDES
285ListeriosisOFFSIDES
286Livedo ReticularisOFFSIDES
287Liver AbscessOFFSIDES
288Lumbar radiculopathyOFFSIDES
289Lung consolidationOFFSIDES
290Lung hyperinflationOFFSIDES
291Lymphocyte transformation test positiveOFFSIDES
292MalaiseSIDER
293Malignant neoplasm progressionOFFSIDES
294Mallory-Weiss SyndromeOFFSIDES
295MalnutritionSIDER
296Mastication disorderOFFSIDES
297MastoiditisOFFSIDES
298Meningioma17019386CTD
299Mental disorder due to a general medical conditionOFFSIDES
300Mental impairmentOFFSIDES
301Metastatic Renal Cell CarcinomaOFFSIDES
302MetatarsalgiaOFFSIDES
303MicrocephalyOFFSIDES
304MonocytosisOFFSIDES
305Mood disorder due to a general medical conditionOFFSIDES
306Morbid thoughtsSIDER
307Multiple MyelomaOFFSIDES
308Muscle WeaknessOFFSIDES
309Muscle necrosisOFFSIDES
310Muscle strainOFFSIDES
311Musculoskeletal PainSIDER
312Musculoskeletal chest painOFFSIDES
SIDER
313Musculoskeletal discomfortSIDER
314MyelitisOFFSIDES
315Myocardial Ischemia4640943CTD
316Myocardial fibrosisOFFSIDES
317NasopharyngitisSIDER
318Necrosis963849
11086739
15786717		CTD
319Nephrogenic Fibrosing DermopathyOFFSIDES
320NephrolithiasisOFFSIDES
321Nephrosis5415710
7003672		CTD
SIDER
322NervousnessSIDER
323NeurilemmomaOFFSIDES
324Neuroleptic Malignant SyndromeOFFSIDES
325Neurological decompensationOFFSIDES
326Neutrophil count decreasedOFFSIDES
327Nodule on extremityOFFSIDES
328Oliguria8529299CTD
OFFSIDES
329OnychoclasisOFFSIDES
330Optic AtrophyOFFSIDES
331Oral candidiasisSIDER
332Oropharyngeal discomfortSIDER
333Oropharyngeal painSIDER
334OsteoporosisOFFSIDES
335PachymeningitisOFFSIDES
336ParaparesisOFFSIDES
337Peripheral embolismOFFSIDES
338Peritoneal DialysisOFFSIDES
339PeritonitisOFFSIDES
340PharyngitisSIDER
341Pharyngolaryngeal PainSIDER
342PhlebitisSIDER
343PlasmacytomaOFFSIDES
344Platelet aggregation inhibitionOFFSIDES
345PolyhydramniosOFFSIDES
346Poor sucking reflexOFFSIDES
347Portal venous gasOFFSIDES
348Post inflammatory pigmentation changeOFFSIDES
349Post procedural complicationOFFSIDES
350Post procedural strokeOFFSIDES
351Post-tussive vomitingSIDER
352Posterior Leukoencephalopathy Syndrome11862771CTD
353Postoperative ileusOFFSIDES
354Postoperative renal failureOFFSIDES
355Procedural complicationOFFSIDES
356Procedural hypotensionOFFSIDES
357ProctitisOFFSIDES
358Productive CoughOFFSIDES
SIDER
359Propofol Infusion SyndromeOFFSIDES
360Protein total decreasedOFFSIDES
361PrurigoSIDER
362PruritusSIDER
363Pulmonary Edema6781355
6784656
21748612		CTD
364Pulmonary Embolism2510358
6766842		CTD
365Pulmonary arterial hypertensionOFFSIDES
366Pulmonary congestionSIDER
367Pulmonary function test decreasedSIDER
368Pulmonary thrombosisOFFSIDES
369Red blood cell schistocytes presentOFFSIDES
370Refusal of treatment by relativeOFFSIDES
371Renal Insufficiency3925648
6781355		CTD
372Renal cystOFFSIDES
373Renal massOFFSIDES
374Renal salt-wasting syndromeOFFSIDES
375Reperfusion Injury21748612CTD
376Respiratory DepressionSIDER
377Respiratory FailureOFFSIDES
378Respiratory tract congestionSIDER
379RetchingSIDER
380Retinal vascular occlusionOFFSIDES
381RhonchiOFFSIDES
382Scan abdomen abnormalOFFSIDES
383Secretion dischargeOFFSIDES
384Septic ShockOFFSIDES
385Shock16302998CTD
386Sinus bradycardiaOFFSIDES
387Skin hypertrophyOFFSIDES
388Skin lacerationOFFSIDES
389Skin necrosisSIDER
390Skin test positiveOFFSIDES
391Skin tightnessOFFSIDES
392SneezingCanada Vigilance: 1Canada Vigilance
393Soft tissue inflammationOFFSIDES
394SoporOFFSIDES
395Spinal corpectomyOFFSIDES
396Spinal fusion surgeryOFFSIDES
397SpondylolisthesisOFFSIDES
398StomatitisSIDER
399Stress ulcerOFFSIDES
400Subcutaneous EmphysemaOFFSIDES
401Sudden Cardiac DeathOFFSIDES
402Suture ruptureOFFSIDES
403TachycardiaSIDER
404TetanyOFFSIDES
405ThirstSIDER
406Throat irritationSIDER
407ThrombophlebitisSIDER
408Thrombosis in deviceOFFSIDES
409Tinea PedisOFFSIDES
410TinnitusOFFSIDES
411Tooth ExtractionOFFSIDES
412Tooth InfectionOFFSIDES
413Transfusion-Related Acute Lung InjuryOFFSIDES
414UlcerOFFSIDES
415Unresponsive to stimuliOFFSIDES
416Urinary IncontinenceSIDER
417Urinary tract infection pseudomonalOFFSIDES
418UrticariaCanada Vigilance: 111792017CTD
SIDER
Canada Vigilance
419Venous ThrombosisSIDER
420Ventricular hypokinesiaOFFSIDES
421VertigoSIDER
422Viral upper respiratory tract infectionOFFSIDES
423Walking aid userOFFSIDES
424Weaning failureOFFSIDES
425WheezingSIDER
426Wound InfectionOFFSIDES
427nervous system disorderSIDER
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120269

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.