MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Metatarsalgia

(UMLS:C0025587)

Definition:: Pain in the region of the METATARSUS. It can include pain in the METATARSAL BONES; METATARSOPHALANGEAL JOINT; and/or intermetatarsal joints (TARSAL JOINTS).
UMLS ID:: C0025587
MeSH ID:: D037061

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.360.500|C05.550.610

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.888.592.612.540

Synonym(s)

Metatarsalgia

METATARSALGIA

Metatarsalgia, unspecified foot

Pain in ball of foot

metatarsalgia

metatarsalgias

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 15	US FAERS
2	tofacitinib	FAERS: 6	US FAERS
3	Fingolimod Hydrochloride	FAERS: 4	US FAERS
4	Isotretinoin	FAERS: 4	US FAERS
5	Deferasirox	FAERS: 2	US FAERS
6	Finasteride	FAERS: 2	US FAERS
7	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
8	Atorvastatin	FAERS: 1	US FAERS
9	Ciprofloxacin	FAERS: 1	US FAERS
10	Diovan Hct	FAERS: 1	US FAERS
11	Levofloxacin	FAERS: 1	US FAERS
12	Octreotide	FAERS: 1	US FAERS
13	Omeprazole	FAERS: 1	US FAERS
14	Ruxolitinib phosphate	FAERS: 1	US FAERS
15	Albuterol		OFFSIDES
16	Amiodarone		OFFSIDES
17	Aripiprazole		OFFSIDES
18	Baclofen		OFFSIDES
19	Budesonide		OFFSIDES
20	Calcium Compounds		OFFSIDES
21	Cefepime		OFFSIDES
22	Cefuroxime		OFFSIDES
23	Codeine		OFFSIDES
24	Diazepam		OFFSIDES
25	Digoxin		OFFSIDES
26	Diltiazem		OFFSIDES
27	Docusate sodium		OFFSIDES
28	Doxazosin		OFFSIDES
29	Ephedrine		OFFSIDES
30	Ertapenem		OFFSIDES
31	Estradiol		OFFSIDES
32	Estrogens, Conjugated (USP)		OFFSIDES
33	Fluconazole		OFFSIDES
34	Hydrocortisone sodium succinate		OFFSIDES
35	Imipramine		OFFSIDES
36	Isoflurane		OFFSIDES
37	Levodopa		OFFSIDES
38	Magnesium		OFFSIDES
39	Mannitol		OFFSIDES
40	Metformin		OFFSIDES
41	Methotrexate		OFFSIDES
42	Methylprednisolone Hemisuccinate		OFFSIDES
43	Metoclopramide		OFFSIDES
44	Misoprostol		OFFSIDES
45	Naproxen		OFFSIDES
46	Olmesartan Medoxomil		OFFSIDES
47	Omeprazole		OFFSIDES
48	Ondansetron		OFFSIDES
49	Pamidronate		OFFSIDES
50	Pancuronium		OFFSIDES
51	Pilocarpine		OFFSIDES
52	Prednisone		OFFSIDES
53	Primidone		OFFSIDES
54	Pyrazinamide		OFFSIDES
55	Sulfasalazine		OFFSIDES
56	Sulfate		OFFSIDES
57	Tiagabine		OFFSIDES
58	Topiramate		OFFSIDES
59	Valacyclovir		OFFSIDES
60	Venlafaxine Hydrochloride		OFFSIDES
61	alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination		OFFSIDES
62	azelastine		OFFSIDES
63	benazepril		OFFSIDES
64	candesartan cilexetil		OFFSIDES
65	candesartan		OFFSIDES
66	cefpodoxime proxetil		OFFSIDES
67	cefpodoxime		OFFSIDES
68	isosorbide-5-mononitrate		OFFSIDES
69	rizatriptan		OFFSIDES
70	rizatriptan		OFFSIDES
71	tegaserod		OFFSIDES
72	tegaserod		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Contracture	33.6%
2	Osteoarthropathy, Secondary Hypertrophic	33.6%
3	Fasciitis, Plantar	33.6%
4	Periarthritis	32.7%
5	Arthrogryposis	31.8%
6	Arthralgia	29.8%
7	Polyarthralgia	29.8%
8	Osteoarthritis, Spine	29%
9	Ankylosing spondylitis	28%
10	Arthritis	27.8%
11	Bursitis	27.8%
12	Joint Instability	27.8%
13	Synovitis	27.8%
14	Joint laxity	27.8%
15	Polyarthritis	27.8%
16	Frozen shoulder	27.8%
17	Patellofemoral Pain Syndrome	27.8%
18	Gout	27%
19	Abdominal Pain	26.4%
20	Back Pain	25.4%
21	Neck Pain	25.4%
22	Chest Pain	25.4%
23	Facial Pain	25.4%
24	Flank Pain	25.4%
25	Headache	25.4%
26	Pain, Intractable	25.4%
27	Pelvic Pain	25.4%
28	Chronic pain	25.4%
29	Pain, Referred	25.4%
30	Throbbing Headache	25.4%
31	Labor Pain	25.4%
32	Cancer Pain	25.4%
33	Nociceptive Pain	25.4%
34	Hip Contracture	24.5%
35	Hemarthrosis	24.1%
36	Arthritis, Psoriatic	23.9%
37	Temporomandibular Joint Disorders	23.4%
38	Ischemic contracture	23.2%
39	Rheumatic Fever	22.7%
40	Musculoskeletal Pain	22.3%
41	Pain, Postoperative	22.3%
42	Eye pain	22.2%
43	Arthritis, Reactive	22%
44	Shoulder Pain	22%
45	Renal Colic	21.6%
46	Bone Diseases	21.6%
47	Fasciitis	21.6%
48	Foot Deformities	21.6%
49	Osteoarthritis, Knee	21.6%
50	Arthritis, Gouty	21.5%
51	Sacroiliitis	20.5%
52	Temporomandibular Joint Dysfunction Syndrome	20.4%
53	Neuralgia	20.3%
54	Neuropathic pain	20.3%
55	Rheumatoid Arthritis	19.7%
56	Juvenile arthritis	19.7%
57	Spondylarthropathies	19.4%
58	Abdomen, Acute	19.1%
59	Low Back Pain	19%
60	Visceral Pain	19%
61	Pectus carinatum	18.9%
62	Fibromyalgia	18.5%
63	Osteochondritis	18.5%
64	Polymyalgia Rheumatica	18.5%
65	Psychophysiologic Disorders	17.9%
66	Rheumatoid Nodule	17.9%
67	Jaw Diseases	17.8%
68	Platybasia	17.3%
69	Cartilage Diseases	17.3%
70	Myopathy	17.3%
71	Rheumatism	17.3%
72	Chondromalacia	17.3%
73	Dysmenorrhea	17.2%
74	Failed Back Surgery Syndrome	17.2%
75	Muscle Weakness	17.2%
76	Muscle Cramp	17%
77	Mastodynia	16.9%
78	Breakthrough Pain	16.8%
79	Arthritis, Infectious	16.6%
80	Arthritis, Experimental	16.3%
81	Myalgia	16.1%
82	Pectus excavatum	16%
83	Nail-Patella Syndrome	15.8%
84	Talipes	15.7%
85	Toothache	15.4%
86	Felty Syndrome	15.3%
87	Muscle Rigidity	14.9%
88	Muscle Spasticity	14.9%
89	Cogwheel Rigidity	14.9%
90	Nuchal Rigidity	14.9%
91	Klippel-Feil Syndrome	14.8%
92	Synostosis	14.8%
93	Decerebrate State	14.5%
94	Hemiparesis	14.5%
95	Meningism	14.5%
96	Paresis	14.5%
97	Seizures	14.5%
98	Sensation Disorders	14.5%
99	Complex partial seizures	14.5%
100	Monoparesis	14.5%
101	Gait Disorders, Neurologic	14.5%
102	Neuromuscular Manifestations	14.5%
103	Phantom pain	14.5%
104	Phantom Limb Pain	14.5%
105	Orthostatic intolerance	14.3%
106	Acrocephalosyndactylia	14.2%
107	Polydipsia	14%
108	Bone Diseases, Developmental	13.9%
109	Hyperostosis	13.9%
110	Myofascial Pain Syndromes	13.9%
111	Osteitis	13.9%
112	Osteitis Deformans	13.9%
113	Osteochondrosis	13.9%
114	Rhabdomyolysis	13.9%
115	Spinal Diseases	13.9%
116	Hip Dislocation	13.9%
117	Shoulder Dislocation	13.9%
118	Hip Dysplasia	13.9%
119	Craniosynostosis	13.7%
120	Syndactyly	13.7%
121	Brachycephaly	13.7%
122	Gigantism	13.6%
123	Spinal Neoplasms	13.6%
124	Spondylitis	13.6%
125	Congenital clubfoot	13.4%
126	Vertical Talus	13.4%
127	Rheumatoid Vasculitis	13.3%
128	Aseptic Necrosis of Bone	13.1%
129	Asthenia	13%
130	Body Temperature Changes	13%
131	Cyanosis	13%
132	Edema	13%
133	Failure to Thrive	13%
134	Fatigue	13%
135	Feminization	13%
136	Fetal Distress	13%
137	Motion Sickness	13%
138	Signs and Symptoms, Digestive	13%
139	Signs and Symptoms, Respiratory	13%
140	Skin Manifestations	13%
141	Chills	13%
142	Lassitude	13%
143	Pseudophakia	13%
144	Urological Manifestations	13%
145	Mobility Limitation	13%
146	Somnolence	13%
147	Sleep Wake Disorders	12.7%
148	Angina Pectoris	12.6%
149	Sciatica	12.4%
150	Pupil Disorders	12.4%
151	Neurobehavioral Manifestations	12.4%
152	Craniofacial Dysostosis	12.3%
153	Asterixis	12%
154	Ballismus	12%
155	Vertigo	11.9%
156	Dizziness	11.9%
157	Lightheadedness	11.9%
158	Sicca Syndrome	11.9%
159	Sjogren's Syndrome	11.9%
160	Poland Syndrome	11.7%
161	Gait Ataxia	11.6%
162	Bone Diseases, Endocrine	11.5%
163	Bone Diseases, Infectious	11.2%
164	Bone neoplasms	11.2%
165	Compartment syndromes	11.2%
166	Maxillary Diseases	11.2%
167	Osteopenia	11.2%
168	Tendinitis	11.2%
169	Tendinopathy	11.2%
170	Discitis	11.1%
171	Bone Resorption	11%
172	Myositis	11%
173	Tietze's Syndrome	11%
174	Limb Deformities, Congenital	11%
175	Isaacs syndrome	11%
176	Craniofacial Abnormalities	11%
177	Myotonic Disorders	11%
178	Arthropathy	10.8%
179	Eye Manifestations	10.8%
180	Cardiac Output, High	10.5%
181	Myocardial Stunning	10.5%
182	Reticulocytosis	10.5%
183	Low Cardiac Output Syndrome	10.5%
184	Voice Disorders	10.4%
185	Voice Disturbance	10.4%
186	Angina, Unstable	10.4%
187	Intermittent Claudication	10.3%
188	Ainhum	10.3%
189	Bunion	10.3%
190	Dysostoses	10.3%
191	Fibrodysplasia Ossificans Progressiva	10.3%
192	Myoglobinuria	10.3%
193	Myositis Ossificans	10.3%
194	Spinal Stenosis	10.3%
195	Spondylosis	10.3%
196	Tenosynovitis	10.3%
197	Intervertebral Disc Degeneration	10.3%
198	Gastroschisis	10.2%
199	Akathisia	10.2%
200	Restlessness	10.2%
201	Psychomotor Agitation	10.2%
202	Prognathism	9.9%
203	Jaw Abnormalities	9.8%
204	Goldenhar Syndrome	9.6%
205	Muscular Atrophy	9.6%
206	Anosmia	9.5%
207	Ataxia	9.5%
208	Athetosis	9.5%
209	Catalepsy	9.5%
210	Dystonia	9.5%
211	Femur Head Necrosis	9.5%
212	Hemiplegia	9.5%
213	Locked-In Syndrome	9.5%
214	Muscle Hypertonia	9.5%
215	Muscle hypotonia	9.5%
216	Myoclonus	9.5%
217	Myotonia	9.5%
218	Paraplegia	9.5%
219	Pseudobulbar Palsy	9.5%
220	Quadriplegia	9.5%
221	Spasm	9.5%
222	Spastic Paraplegia	9.5%
223	Status Epilepticus	9.5%
224	Taste Disorders	9.5%
225	Tremor	9.5%
226	Monoplegia	9.5%
227	Hypokinesia	9.5%
228	Gastroparesis	9.5%
229	Paraparesis	9.5%
230	Bradykinesia	9.5%
231	Waxy flexibility	9.5%
232	Action Tremor	9.5%
233	Resting Tremor	9.5%
234	Dysosmia	9.5%
235	Quadriparesis	9.5%
236	Olfaction Disorders	9.5%
237	Myokymia	9.5%
238	Somatosensory Disorders	9.5%
239	Hyperkinesia	9.5%
240	Intention tremor	9.5%
241	Tuberculosis, Spinal	9.4%
242	Gait Apraxia	9.4%
243	Congenital Hypothyroidism	9.3%
244	Giant Cell Epulis	9.3%
245	Angina Pectoris, Variant	9.3%
246	Medial Tibial Stress Syndrome	9.2%
247	Metatarsalgia	9.2%
248	Mitochondrial Myopathies	9.1%
249	Eosinophilia-Myalgia Syndrome	9.1%
250	Mandibulofacial Dysostosis	9%
251	Reflex, Abnormal	8.8%
252	Hyporeflexia	8.8%
253	Hyperreflexia	8.8%
254	Antley-Bixler Syndrome Phenotype	8.7%
255	Hypergammaglobulinemia	8.7%
256	Hoarseness	8.6%
257	Foot Diseases	8.6%
258	Chondrodysplasia Punctata	8.5%
259	Enchondromatosis	8.5%
260	Lordosis	8.5%
261	Osteosclerosis	8.5%
262	Spondylolysis	8.5%
263	kyphosis	8.5%
264	Kashin-Beck Disease	8.5%
265	Postoperative Nausea and Vomiting	8.4%
266	Multiple Epiphyseal Dysplasia	8.3%
267	Osteochondrodysplasias	8.3%
268	Anterior Compartment Syndrome	8.2%
269	Osteomyelitis	8.2%
270	Osteoporosis	8.2%
271	Periostitis	8.2%
272	Enthesopathy	8.2%
273	Bone Demineralization, Pathologic	8.2%
274	Post-Traumatic Osteoporosis	8.2%
275	Abdominal Compartment Syndrome	8.2%
276	jaundice	8.2%
277	Vision Disorders	8.1%
278	Metamorphopsia	8.1%
279	Visual Impairment	8.1%
280	Chronic Fatigue Syndrome	8.1%
281	Alveolar Bone Loss	8.1%
282	Amelia	8.1%
283	Arachnodactyly	8.1%
284	Ectromelia	8.1%
285	Hemimelia	8.1%
286	Phocomelia	8.1%
287	Sirenomelia	8.1%
288	Polymyositis	8.1%
289	Polydactyly	8.1%
290	Brachydactyly	8.1%
291	Plagiocephaly	8.1%
292	Lower Extremity Deformities, Congenital	8.1%
293	Upper Extremity Deformities, Congenital	8.1%
294	Pathological Conditions, Anatomical	8.1%
295	Osteolysis	8.1%
296	Eosinophilic Granuloma	8%
297	Anisocoria	8%
298	Confusion	8%
299	Facial paralysis	8%
300	Lethargy	8%
301	Memory Disorders	8%
302	Perceptual Disorders	8%
303	Psychomotor Disorders	8%
304	Tonic Pupil	8%
305	Anhedonia	8%
306	Disorientation	8%
307	Facial Paresis	8%
308	Memory Loss	8%
309	Hemisensory Neglect	8%
310	Dysacusis	8%
311	Respiratory Paralysis	7.9%
312	Chorea	7.8%
313	Tetany	7.8%
314	Palatal Neoplasms	7.7%
315	Familial Periodic Paralysis	7.7%
316	Micrognathism	7.7%
317	Pierre Robin Syndrome	7.7%
318	Anorexia	7.7%
319	Anoxia	7.7%
320	Constipation	7.7%
321	Diarrhea	7.7%
322	Dyspepsia	7.7%
323	Eructation	7.7%
324	Fever	7.7%
325	Flatulence	7.7%
326	Flushing	7.7%
327	Halitosis	7.7%
328	Heartburn	7.7%
329	Hiccough	7.7%
330	Hypercalciuria	7.7%
331	Hypercapnia	7.7%
332	Hyperphagia	7.7%
333	Nausea	7.7%
334	Pallor	7.7%
335	Vomiting	7.7%
336	Hypocapnia	7.7%
337	Dyschezia	7.7%
338	Hypoxia	7.7%
339	Hyperoxia	7.7%
340	Lower Urinary Tract Symptoms	7.7%
341	Hypoxemia	7.7%
342	Urinoma	7.7%
343	Alice in Wonderland Syndrome	7.7%
344	Melorheostosis	7.6%
345	Osteopetrosis	7.6%
346	Spondylolisthesis	7.6%
347	Rubinstein-Taybi Syndrome	7.3%
348	Myotonic Dystrophy	7.3%
349	Alexia	7.2%
350	Dyslexia	7.2%
351	Dwarfism	7.1%
352	Dysgeusia	7%
353	Formication	7%
354	Hyperalgesia	7%
355	Hyperesthesia	7%
356	Hypesthesia	7%
357	Language Disorders	7%
358	Numbness	7%
359	Paresthesia	7%
360	Paraparesis, Spastic	7%
361	Trismus	7%
362	Epilepsia Partialis Continua	7%
363	Hypogeusia	7%
364	Brown-Sequard Syndrome	7%
365	Lockjaw	7%
366	Allodynia	7%
367	Ageusia	7%
368	Eye Hemorrhage	7%
369	Retrognathia	6.9%
370	Laryngomalacia	6.9%
371	Sarcopenia	6.9%
372	Consciousness Disorders	6.9%
373	Mental Retardation	6.9%
374	Depressed Level of Consciousness	6.9%
375	Mental deficiency	6.9%
376	Intellectual Disability	6.9%
377	Hemoptysis	6.9%
378	Muscular Dystrophy	6.8%
379	Orbital Myositis	6.8%
380	Catatonia	6.8%
381	Ophthalmoplegia	6.8%
382	External Ophthalmoplegia	6.8%
383	Dupuytren Contracture	6.8%
384	Ecchymosis	6.8%
385	Petechiae	6.8%
386	Purpura	6.8%
387	Pyomyositis	6.7%
388	Aphonia	6.7%
389	Sleep Deprivation	6.7%
390	Dysphonia	6.7%
391	Acromegaly	6.7%
392	Joint Tuberculosis	6.7%
393	Tuberculosis, Osteoarticular	6.7%
394	Bone Tuberculosis	6.7%
395	Osteoporosis, Postmenopausal	6.7%
396	Cerebrospinal Fluid Otorrhea	6.7%
397	Cerebrospinal Fluid Rhinorrhea	6.7%
398	Body Weight	6.3%
399	Apnea	6.2%
400	Cheyne-Stokes Respiration	6.2%
401	Dyspnea	6.2%
402	Hyperventilation	6.2%
403	Mouth Breathing	6.2%
404	Pruritus	6.2%
405	Sneezing	6.2%
406	Erythema	6.2%
407	Necrolytic Migratory Erythema	6.2%
408	Tachypnea	6.2%
409	Edema, Cardiac	6.1%
410	Mental Fatigue	6.1%
411	Hirsutism	6.1%
412	Hypoventilation	6.1%
413	Basal Cell Nevus Syndrome	6.1%
414	Body Weight Changes	6.1%
415	Vocal Cord Paralysis	6%
416	Diplopia	5.9%
417	Scotoma	5.9%
418	Photophobia	5.9%
419	Hemifacial Spasm	5.9%
420	Amaurosis	5.9%
421	Blindness	5.9%
422	Epistaxis	5.9%
423	Agnosia	5.8%
424	Apraxias	5.8%
425	Hallucinations	5.8%
426	Hemianopsia	5.8%
427	Hyperacusis	5.8%
428	Tinnitus	5.8%
429	Visual Agnosia	5.8%
430	Anosognosia	5.8%
431	Wernicke-Korsakoff Syndrome	5.8%
432	Phonophobia	5.8%
433	Hearing Loss	5.8%
434	Vascular Remodeling	5.8%
435	Maxillofacial Abnormalities	5.8%
436	Agraphia	5.8%
437	Anomia	5.8%
438	Cluttering	5.8%
439	Language Development Disorders	5.8%
440	Speech Disorders	5.8%
441	Syncope	5.8%
442	Stupor	5.8%
443	Dysgraphia	5.8%
444	Presyncope	5.8%
445	Dyslalia	5.8%
446	Cerebellar Ataxia	5.8%
447	Torticollis	5.8%
448	Tardive Dyskinesia	5.8%
449	Cleft Palate	5.8%
450	Myotonia Congenita	5.8%
451	Rickets	5.7%
452	Bronchomalacia	5.7%
453	Tracheomalacia	5.7%
454	Microcephaly	5.7%
455	Macrocephaly	5.7%
456	Hypokalemic periodic paralysis	5.7%
457	Osteogenesis Imperfecta	5.7%
458	Welander Distal Myopathy	5.6%
459	Mastoiditis	5.6%
460	Petrositis	5.6%
461	Jaundice, Obstructive	5.4%
462	Dyskinesia, Drug-Induced	5.3%
463	Aphasia	5.2%
464	Articulation Disorders	5.2%
465	Echolalia	5.2%
466	Stuttering	5.2%
467	Dysphasia	5.2%
468	Alcohol Withdrawal Seizures	5.2%
469	Pleural Rub	5.1%
470	Rales	5.1%
471	Respiratory Sounds	5.1%
472	Rhonchi	5.1%
473	Stridor	5.1%
474	Wheezing	5.1%
475	Bulimia	5.1%
476	Dysuria	5.1%
477	Fever of Unknown Origin	5.1%
478	Nocturia	5.1%
479	Snoring	5.1%
480	Livedo Reticularis	5.1%
481	Prostatism	5.1%
482	Amblyopia	5.1%
483	Amnesia	5.1%
484	Delirium	5.1%
485	Horner Syndrome	5.1%
486	Dissociative Amnesia	5.1%
487	Color blindness	5.1%
488	Global Amnesia	5.1%
489	Oliguria	5.1%
490	Polyuria	5.1%
491	Proteinuria	5.1%
492	Pseudohypoparathyroidism	5%
493	Mitochondrial Encephalomyopathies	5%
494	Underweight	5%
495	Overweight	5%
496	Dysarthria	4.9%
497	Dermatomyositis	4.9%
498	Amaurosis Fugax	4.9%
499	Blindness, Cortical	4.9%
500	Dyscalculia	4.9%
501	Deafness	4.8%
502	Hearing Loss, Sudden	4.8%
503	Gerstmann Syndrome	4.8%
504	Hearing Loss, Bilateral	4.8%
505	Hearing Loss, High-Frequency	4.8%
506	Hearing Loss, Mixed Conductive-Sensorineural	4.8%
507	Prosopagnosia	4.8%
508	Apraxia, Ideomotor	4.8%
509	Persistent Vegetative State	4.8%
510	Charles Bonnet Syndrome	4.8%
511	Hearing Loss, Unilateral	4.8%
512	Complete Hearing Loss	4.8%
513	Alien Hand Syndrome	4.8%
514	Deaf Mutism	4.8%
515	Muscular Dystrophy, Duchenne	4.8%
516	Osteomalacia	4.7%
517	Porencephaly	4.7%
518	Kearns-Sayre syndrome	4.7%
519	Noonan Syndrome	4.5%
520	Akathisia, Drug-Induced	4.5%
521	Hematemesis	4.5%
522	Purpura Fulminans	4.4%
523	Mutism	4.4%
524	Selective Mutism	4.4%
525	Gagging	4.4%
526	Ascites	4.3%
527	Calculi	4.3%
528	Fibrosis	4.3%
529	Gliosis	4.3%
530	Growth Disorders	4.3%
531	Hemorrhage	4.3%
532	Hernia	4.3%
533	Hyperbilirubinemia	4.3%
534	Hyperplasia	4.3%
535	Hypertrophy	4.3%
536	Hypomenorrhea	4.3%
537	Inflammation	4.3%
538	Intraoperative Complications	4.3%
539	Ischemia	4.3%
540	Lithiasis	4.3%
541	Malacoplakia	4.3%
542	Menstruation Disturbances	4.3%
543	Metaplasia	4.3%
544	Nails, Malformed	4.3%
545	Nerve Degeneration	4.3%
546	Ochronosis	4.3%
547	Polymenorrhea	4.3%
548	polyps	4.3%
549	Postoperative Complications	4.3%
550	Rupture, Spontaneous	4.3%
551	Sclerosis	4.3%
552	Shock	4.3%
553	Ulcer	4.3%
554	Enterocele	4.3%
555	Hyperammonemia	4.3%
556	Hyperamylasemia	4.3%
557	Teratogenesis	4.3%
558	Atheroma	4.3%
559	Cardiac Death	4.3%
560	Hypovolemia	4.3%
561	Hyperuricemia	4.3%
562	Leukoaraiosis	4.3%
563	Stenosis	4.3%
564	Facial asymmetry	4.3%
565	Dysbacteriosis	4.3%
566	Delayed Graft Function	4.3%
567	Cirrhosis	4.3%
568	Plaque, Amyloid	4.3%
569	Plaque, Atherosclerotic	4.3%
570	Neointima	4.3%
571	Dysbiosis	4.3%
572	Retrograde amnesia	4.1%
573	Amnesia, Anterograde	4.1%
574	Alexia, Pure	4.1%
575	Morning Sickness	4.1%
576	Infarction	4.1%
577	Marfan Syndrome	4.1%
578	Postoperative Hemorrhage	4.1%
579	Shock, Hemorrhagic	4.1%
580	Systemic Inflammatory Response Syndrome	4.1%
581	Incisional hernia	4.1%
582	Holoprosencephaly	4%
583	Weight Gain	4%
584	Auditory Perceptual Disorders	3.9%
585	Emaciation	3.8%
586	Jet Lag Syndrome	3.8%
587	Cockayne Syndrome	3.7%
588	Radicular Cyst	3.7%
589	Birth Weight	3.7%
590	Amnesia, Transient Global	3.6%
591	Cyst	3.6%
592	Extravasation of Diagnostic and Therapeutic Materials	3.6%
593	Neoplastic Processes	3.6%
594	Ophthalmoplegic Migraine	3.5%
595	Leukoplakia	3.5%
596	Necrosis	3.5%
597	Granulomatosis, Orofacial	3.5%
598	Pigmentation Disorders	3.5%
599	Respiratory Aspiration	3.5%
600	Airway Remodeling	3.5%
601	Progressive supranuclear palsy	3.5%
602	Acantholysis	3.4%
603	Chromosome Aberrations	3.4%
604	Dehydration	3.4%
605	Granuloma	3.4%
606	Leukocytosis	3.4%
607	Pleocytosis	3.4%
608	Ventricular Remodeling	3.4%
609	Alopecia	3.4%
610	Nose Neoplasms	3.4%
611	Androgenetic Alopecia	3.4%
612	Fetal Hypoxia	3.4%
613	Thrombocytopenic purpura	3.4%
614	Dyspnea, Paroxysmal	3.4%
615	Urinary Incontinence	3.4%
616	Albuminuria	3.3%
617	Hemoglobinuria	3.3%
618	Purpura, Hyperglobulinemic	3.3%
619	Renal Osteodystrophy	3.3%
620	Renal rickets	3.3%
621	Cachexia	3.2%
622	Hyperemesis Gravidarum	3%
623	Hydrops Fetalis	3%
624	Fetal Weight	3%
625	Genomic Instability	3%
626	Chromosomal Instability	2.9%
627	Obesity	2.8%
628	Diverticulum	2.8%
629	Diverticulosis	2.8%
630	Azotemia	2.8%
631	Menorrhagia	2.8%
632	MELAS Syndrome	2.7%
633	Sudden infant death syndrome	2.7%
634	Acute Disease	2.6%
635	Acute-Phase Reaction	2.6%
636	Amenorrhea	2.6%
637	Chronic disease	2.6%
638	Critical Illness	2.6%
639	Sudden death	2.6%
640	Fat necrosis	2.6%
641	Gangrene	2.6%
642	Graft Occlusion, Vascular	2.6%
643	Granuloma, Plasma Cell	2.6%
644	Hematoma	2.6%
645	Diaphragmatic Hernia	2.6%
646	Iatrogenic Disease	2.6%
647	Intestinal Polyps	2.6%
648	Multiple Organ Failure	2.6%
649	Oligomenorrhea	2.6%
650	Premenstrual syndrome	2.6%
651	Recurrence	2.6%
652	Retrograde Degeneration	2.6%
653	Retroperitoneal fibrosis	2.6%
654	Serositis	2.6%
655	Splenomegaly	2.6%
656	Subcutaneous Emphysema	2.6%
657	Surgical Wound Dehiscence	2.6%
658	Syndrome	2.6%
659	Wallerian Degeneration	2.6%
660	Pyogenic granuloma	2.6%
661	Exsanguination	2.6%
662	Disease Progression	2.6%
663	Seroma	2.6%
664	Premenstrual Tension	2.6%
665	Delayed Emergence from Anesthesia	2.6%
666	Infant Death	2.6%
667	Anastomotic Leak	2.6%
668	Intraoperative Awareness	2.6%
669	Urge Incontinence	2.5%
670	Cardiotoxicity	2.5%
671	Tinea Pedis	2.5%
672	Purpura, Thrombotic Thrombocytopenic	2.5%
673	Waterhouse-Friderichsen Syndrome	2.2%
674	Asphyxia	2.1%
675	Granuloma, Respiratory Tract	2.1%
676	Shock, Traumatic	2.1%
677	Respiratory Tract Fistula	2.1%
678	Pediatric Obesity	2.1%
679	Disease susceptibility	2.1%
680	Fetal Death	2.1%
681	Foreign-Body Reaction	2.1%
682	Gastrointestinal Hemorrhage	2.1%
683	Cardiomegaly	2.1%
684	Hemoperitoneum	2.1%
685	Hemothorax	2.1%
686	Hepatomegaly	2.1%
687	Neoplasm Invasiveness	2.1%
688	Neoplasm Metastasis	2.1%
689	Neoplasm Recurrence, Local	2.1%
690	Parovarian Cyst	2.1%
691	Postpericardiotomy Syndrome	2.1%
692	Prosthesis Failure	2.1%
693	Reperfusion Injury	2.1%
694	Spermatocele	2.1%
695	Oral Fistula	2.1%
696	Injection Site Reaction	2.1%
697	Retrobulbar Hemorrhage	2.1%
698	Cutaneous Fistula	2.1%
699	Peritoneal Fibrosis	2.1%
700	Carcinogenesis	2.1%
701	Neurogenic Inflammation	2.1%
702	Perinatal death	2.1%
703	Infusion site reaction	2.1%
704	Cardiac Hypertrophy	2.1%
705	Nephrogenic Fibrosing Dermopathy	2.1%
706	Corneal Endothelial Cell Loss	2.1%
707	Encapsulating Peritoneal Sclerosis	2.1%
708	Vasoplegia	2.1%
709	Suppuration	2.1%
710	Nephrogenic Systemic Fibrosis	2.1%
711	Metastasis	2.1%
712	Sinus Arrhythmia	2%
713	Atrial Fibrillation	2%
714	Atrial Flutter	2%
715	Dental Pulp Necrosis	2%
716	Granuloma, Foreign-Body	2%
717	Mediastinal Emphysema	2%
718	Surgical Wound Infection	2%
719	Ventricular Fibrillation	2%
720	Ventricular Flutter	2%
721	Parasystole	2%
722	Paroxysmal atrial fibrillation	2%
723	Facies	2%
724	Bradycardia	2%
725	Embryo Loss	2%
726	Afferent Loop Syndrome	2%
727	Sex Chromosome Aberrations	2%
728	Short Bowel Syndrome	2%
729	Uterine hemorrhage	2%
730	Vaginal Fistula	2%
731	Rectocele	2%
732	No-Reflow Phenomenon	2%
733	Autoimmune thrombocytopenia	2%
734	Immune thrombocytopenic purpura	2%
735	Endotoxic shock	1.9%
736	Septic Shock	1.9%
737	Toxic Shock Syndrome	1.9%
738	Familial Hypophosphatemic Rickets	1.9%
739	Chromosome Fragility	1.9%
740	Drowning	1.8%
741	Nasal Polyps	1.7%
742	Fetal Growth Retardation	1.7%
743	DNA Degradation, Necrotic	1.7%
744	Aneuploidy	1.7%
745	Polyploidy	1.7%
746	Microsatellite Instability	1.7%
747	Tissue Adhesions	1.7%
748	Colonic Polyps	1.7%
749	Heart Block	1.7%
750	Tachycardia	1.7%
751	Tachyarrhythmia	1.7%
752	Hematoma, Epidural, Spinal	1.7%
753	Cicatrix	1.7%
754	Hematuria	1.7%
755	Meningocele	1.7%
756	Urinary Calculi	1.7%
757	Granuloma Annulare	1.7%
758	Chromosome Breakage	1.7%
759	Encephalocele	1.7%
760	Brain Death	1.7%
761	Shock, Cardiogenic	1.7%
762	Sick Sinus Syndrome	1.7%
763	Trisomy	1.7%
764	Hematoma, Subdural	1.5%
765	Hematoma, Epidural, Cranial	1.5%
766	Leukoplakia, Oral	1.4%
767	Long QT Syndrome	1.4%
768	Vesicovaginal Fistula	1.4%
769	Micronuclei, Chromosome-Defective	1.4%
770	Biliary Fistula	1.4%
771	Cross Infection	1.4%
772	Gastric Fistula	1.4%
773	Hyphema	1.4%
774	Retinal Neovascularization	1.4%
775	Septicemia	1.4%
776	Vitreous Hemorrhage	1.4%
777	Congenital diaphragmatic hernia	1.4%
778	Sepsis	1.4%
779	Abscess	1.4%
780	Dental Fistula	1.4%
781	Empyema	1.4%
782	Fetal Resorption	1.4%
783	Lymphatic Metastasis	1.4%
784	Neoplasms, Unknown Primary	1.4%
785	Oroantral Fistula	1.4%
786	Peptic Ulcer Hemorrhage	1.4%
787	Sudden Cardiac Death	1.4%
788	Left Ventricular Hypertrophy	1.4%
789	Leukemic Infiltration	1.4%
790	Right Ventricular Hypertrophy	1.4%
791	Premenstrual Dysphoric Disorder	1.4%
792	Choroidal Neovascularization	1.4%
793	Primary Graft Dysfunction	1.4%
794	Neoplasm Micrometastasis	1.4%
795	Dumping Syndrome	1.3%
796	Rectal Prolapse	1.3%
797	Uterine Prolapse	1.3%
798	Cicatrix, Hypertrophic	1.3%
799	Vaginal Prolapse	1.3%
800	Sinus Arrest, Cardiac	1.3%
801	Metrorrhagia	1.3%
802	Subacute Combined Degeneration	1.3%
803	Hematoma, Subdural, Spinal	1.3%
804	Bronchial Fistula	1.1%
805	Pancreatic Fistula	1.1%
806	Retinal Hemorrhage	1.1%
807	Choroid Hemorrhage	1.1%
808	Intestinal Fistula	1.1%
809	Melena	1.1%
810	Enterocutaneous Fistula	1.1%
811	Kernicterus	1.1%
812	Postpartum Hemorrhage	1.1%
813	Salivary Gland Fistula	1.1%
814	Cystocele	1.1%
815	Gingival Hemorrhage	1.1%
816	Keloid	1.1%
817	Monosomy	1.1%
818	Tetraploidy	1.1%
819	Stillbirth	1.1%
820	Adams-Stokes Syndrome	1.1%
821	Atrioventricular Block	1.1%
822	Bundle-Branch Block	1.1%
823	Atrial Premature Complexes	1.1%
824	Sinoatrial Block	1.1%
825	Tachycardia, Paroxysmal	1.1%
826	Supraventricular tachycardia	1.1%
827	Tachycardia, Ventricular	1.1%
828	Tachycardia, Reciprocating	1.1%
829	Subarachnoid Hemorrhage	1.1%
830	Cerebral Hemorrhage	1.1%
831	Hematoma, Subdural, Intracranial	1.1%
832	Hematoma, Subdural, Chronic	1.1%
833	Hematoma, Subdural, Acute	1.1%
834	Viremia	1.1%
835	Parasitemia	1.1%
836	Umbilical hernia	1%
837	Cellulitis	1%
838	Romano-Ward Syndrome	0.9%
839	Granuloma, Laryngeal	0.9%
840	Bacteremia	0.8%
841	Cell Transformation, Viral	0.8%
842	Myocardial Reperfusion Injury	0.8%
843	Fungemia	0.8%
844	Urinary Bladder Fistula	0.8%
845	Tachycardia, Atrioventricular Nodal Reentry	0.8%
846	Tachycardia, Ectopic Atrial	0.8%
847	Tachycardia, Ectopic Junctional	0.8%
848	Sinus Tachycardia	0.8%
849	Torsades de Pointes	0.8%
850	Accelerated Idioventricular Rhythm	0.8%
851	Arteriovenous fistula	0.7%
852	Philadelphia Chromosome	0.7%
853	Rectal Fistula	0.7%
854	Anal Fistula	0.7%
855	Endotoxemia	0.7%
856	Kidney Calculi	0.7%
857	Ureteral Calculi	0.7%
858	Basal Ganglia Hemorrhage	0.5%
859	Candidemia	0.5%
860	Putaminal Hemorrhage	0.5%

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