MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lordosis

(UMLS:C0024003)

Definition:: The anterior concavity in the curvature of the lumbar and cervical spine as viewed from the side. The term usually refers to abnormally increased curvature (hollow back, saddle back, swayback). It does not include lordosis as normal mating posture in certain animals ( = POSTURE + SEX BEHAVIOR, ANIMAL).
UMLS ID:: C0024003
MeSH ID:: D008141

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.900.800.750

Synonym(s)

Lordosis

Hollow back

Hyperlordosis

Hyperlordotic

LORDOSIS

Lordosis accentuated

Lordosis deformity of spine

Lordosis, NOS

Lordosis, unspecified

10.

Prominent swayback

11.

Saddle back

12.

Swayback

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Valproic Acid	FAERS: 18		US FAERS
2	Alendronate	FAERS: 10		OFFSIDES US FAERS
3	Fentanyl	FAERS: 3		US FAERS
4	Valproic Acid	FAERS: 3		US FAERS
5	Benicar hct	FAERS: 2		US FAERS
6	Ibandronic Acid	FAERS: 2		US FAERS
7	Teriparatide	FAERS: 2		US FAERS
8	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
9	Anastrozole	FAERS: 1		US FAERS
10	Baclofen	FAERS: 1		US FAERS
11	Fingolimod Hydrochloride	FAERS: 1		US FAERS
12	Glatiramer Acetate	FAERS: 1		US FAERS
13	Isotretinoin	FAERS: 1		US FAERS
14	Pamidronate	FAERS: 1		US FAERS
15	Paroxetine	FAERS: 1		US FAERS
16	Propofol	FAERS: 1		US FAERS
17	Risperidone	FAERS: 1		US FAERS
18	Timolol	FAERS: 1		US FAERS
19	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
20	Zoledronic Acid	FAERS: 1		US FAERS
21	tofacitinib	FAERS: 1		US FAERS
22	Carbamazepine			OFFSIDES
23	Chlorhexidine			OFFSIDES
24	Cortisone			OFFSIDES
25	Dextromethorphan		20737414	CTD
26	Estradiol			OFFSIDES
27	Hydralazine			OFFSIDES
28	Ketamine		27359275	CTD
29	Meloxicam			OFFSIDES
30	Methotrimeprazine			OFFSIDES
31	Nicardipine			OFFSIDES
32	Nitrazepam			OFFSIDES
33	Pamidronate			OFFSIDES
34	Pentazocine		4701388	CTD
35	Pramipexole			OFFSIDES
36	Pyridoxine			OFFSIDES
37	Trihexyphenidyl			OFFSIDES
38	Zonisamide			OFFSIDES
39	chlorhexidine gluconate			OFFSIDES
40	ioversol			SIDER
41	rofecoxib			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	kyphosis	48.4%
2	Spinal Stenosis	34.4%
3	Spondylosis	34.4%
4	Intervertebral Disc Degeneration	34.4%
5	Bone Diseases, Developmental	25.4%
6	Hyperostosis	25.4%
7	Osteitis	25.4%
8	Osteitis Deformans	25.4%
9	Osteochondrosis	25.4%
10	Spinal Neoplasms	24.8%
11	Spondylitis	24.8%
12	Osteoarthropathy, Secondary Hypertrophic	23%
13	Spondylolysis	22.6%
14	Platybasia	21.7%
15	Bone Diseases, Endocrine	18.1%
16	Bone Diseases, Infectious	17.2%
17	Bone neoplasms	17.2%
18	Osteopenia	17.2%
19	Osteochondritis	17.1%
20	Bone Resorption	16.9%
21	Aseptic Necrosis of Bone	16.9%
22	Spondylolisthesis	16.8%
23	Fasciitis	16.4%
24	Foot Deformities	16.4%
25	Arthropathy	16.4%
26	Discitis	16.1%
27	Gigantism	14.9%
28	Ainhum	14.8%
29	Dysostoses	14.8%
30	Spondylarthropathies	13.4%
31	Tuberculosis, Spinal	12.8%
32	Pectus excavatum	11.8%
33	Contracture	11.5%
34	Fasciitis, Plantar	11.5%
35	Jaw Diseases	11.4%
36	Osteoarthritis, Spine	11.3%
37	Cartilage Diseases	10.8%
38	Foot Diseases	10.8%
39	Myopathy	10.8%
40	Rheumatism	10.8%
41	Chondromalacia	10.8%
42	Pectus carinatum	10.7%
43	Ankylosing spondylitis	10.7%
44	Arthrogryposis	10.3%
45	Multiple Epiphyseal Dysplasia	10.1%
46	Osteochondrodysplasias	10.1%
47	Osteomyelitis	9.9%
48	Osteoporosis	9.9%
49	Periostitis	9.9%
50	Bone Demineralization, Pathologic	9.9%
51	Post-Traumatic Osteoporosis	9.9%
52	Alveolar Bone Loss	9.8%
53	Femur Head Necrosis	9.8%
54	Osteolysis	9.8%
55	Chondrodysplasia Punctata	9.7%
56	Enchondromatosis	9.7%
57	Osteosclerosis	9.7%
58	Kashin-Beck Disease	9.7%
59	Klippel-Feil Syndrome	9.2%
60	Synostosis	9.2%
61	Fibromyalgia	8.5%
62	Polymyalgia Rheumatica	8.5%
63	Arthritis, Psoriatic	8.5%
64	Arthritis	8.5%
65	Bursitis	8.5%
66	Joint Instability	8.5%
67	Metatarsalgia	8.5%
68	Myofascial Pain Syndromes	8.5%
69	Rhabdomyolysis	8.5%
70	Synovitis	8.5%
71	Joint laxity	8.5%
72	Polyarthritis	8.5%
73	Frozen shoulder	8.5%
74	Patellofemoral Pain Syndrome	8.5%
75	Congenital Hypothyroidism	8.3%
76	Eosinophilic Granuloma	8.2%
77	Dwarfism	8%
78	Arthritis, Reactive	7.9%
79	Acromegaly	7.3%
80	Joint Tuberculosis	7.3%
81	Tuberculosis, Osteoarticular	7.3%
82	Bone Tuberculosis	7.3%
83	Craniofacial Dysostosis	7.3%
84	Melorheostosis	7.2%
85	Osteopetrosis	7.2%
86	Rheumatic Fever	6.7%
87	Hip Contracture	6.6%
88	Periarthritis	6.6%
89	Osteoporosis, Postmenopausal	6.5%
90	Gout	6.1%
91	Ischemic contracture	6%
92	Rickets	5.9%
93	Compartment syndromes	5.7%
94	Maxillary Diseases	5.7%
95	Tendinitis	5.7%
96	Tendinopathy	5.7%
97	Temporomandibular Joint Disorders	5.7%
98	Craniosynostosis	5.7%
99	Syndactyly	5.7%
100	Brachycephaly	5.7%
101	Hemarthrosis	5.6%
102	Myositis	5.6%
103	Tietze's Syndrome	5.6%
104	Limb Deformities, Congenital	5.6%
105	Isaacs syndrome	5.6%
106	Craniofacial Abnormalities	5.6%
107	Myotonic Disorders	5.6%
108	Rheumatoid Arthritis	5.4%
109	Juvenile arthritis	5.4%
110	Osteoarthritis, Knee	5.4%
111	Osteogenesis Imperfecta	5%
112	Bunion	4.9%
113	Fibrodysplasia Ossificans Progressiva	4.9%
114	Myoglobinuria	4.9%
115	Myositis Ossificans	4.9%
116	Pseudohypoparathyroidism	4.9%
117	Tenosynovitis	4.9%
118	Sacroiliitis	4.9%
119	Talipes	4.9%
120	Mastoiditis	4.8%
121	Petrositis	4.8%
122	Acrocephalosyndactylia	4.5%
123	Temporomandibular Joint Dysfunction Syndrome	4.5%
124	Medial Tibial Stress Syndrome	4.3%
125	Mitochondrial Myopathies	4.2%
126	Mandibulofacial Dysostosis	4.2%
127	Muscle Cramp	4.2%
128	Eosinophilia-Myalgia Syndrome	4.2%
129	Goldenhar Syndrome	4.2%
130	Gastroschisis	4.2%
131	Poland Syndrome	4.1%
132	Muscle Rigidity	4.1%
133	Muscle Spasticity	4.1%
134	Cogwheel Rigidity	4.1%
135	Nuchal Rigidity	4.1%
136	Rheumatoid Nodule	4.1%
137	Antley-Bixler Syndrome Phenotype	4%
138	Osteomalacia	3.8%
139	Marfan Syndrome	3.8%
140	Arthritis, Gouty	3.8%
141	Rubinstein-Taybi Syndrome	3.7%
142	Basal Cell Nevus Syndrome	3.6%
143	Chronic Fatigue Syndrome	3.5%
144	Palatal Neoplasms	3.5%
145	Nail-Patella Syndrome	3.4%
146	Giant Cell Epulis	3.4%
147	Muscle Weakness	3.4%
148	Arthritis, Infectious	3.4%
149	Congenital clubfoot	3.4%
150	Vertical Talus	3.4%
151	Musculoskeletal Pain	3.3%
152	Jaw Abnormalities	3.3%
153	Familial Periodic Paralysis	3.3%
154	Anterior Compartment Syndrome	3.3%
155	Enthesopathy	3.3%
156	Arthritis, Experimental	3.3%
157	Abdominal Compartment Syndrome	3.3%
158	Arthralgia	3.3%
159	Polyarthralgia	3.3%
160	Felty Syndrome	3.3%
161	Amelia	3.3%
162	Arachnodactyly	3.3%
163	Ectromelia	3.3%
164	Hemimelia	3.3%
165	Phocomelia	3.3%
166	Sirenomelia	3.3%
167	Polymyositis	3.3%
168	Polydactyly	3.3%
169	Brachydactyly	3.3%
170	Plagiocephaly	3.3%
171	Lower Extremity Deformities, Congenital	3.3%
172	Upper Extremity Deformities, Congenital	3.3%
173	Laryngomalacia	2.9%
174	Cockayne Syndrome	2.8%
175	Myalgia	2.7%
176	Rheumatoid Vasculitis	2.7%
177	Prognathism	2.7%
178	Hip Dislocation	2.6%
179	Shoulder Dislocation	2.6%
180	Hip Dysplasia	2.6%
181	Nose Neoplasms	2.5%
182	Muscular Dystrophy	2.5%
183	Orbital Myositis	2.5%
184	Dupuytren Contracture	2.5%
185	Pyomyositis	2.5%
186	Renal Osteodystrophy	2.4%
187	Renal rickets	2.4%
188	Sicca Syndrome	2.3%
189	Sjogren's Syndrome	2.3%
190	Micrognathism	2.1%
191	Pierre Robin Syndrome	2.1%
192	Myotonic Dystrophy	2%
193	Maxillofacial Abnormalities	2%
194	Myotonia Congenita	2%
195	Bronchomalacia	2%
196	Tracheomalacia	2%
197	Microcephaly	1.9%
198	Macrocephaly	1.9%
199	Hypokalemic periodic paralysis	1.9%
200	Shoulder Pain	1.9%
201	Retrognathia	1.8%
202	Mitochondrial Encephalomyopathies	1.6%
203	Welander Distal Myopathy	1.6%
204	Cleft Palate	1.5%
205	Noonan Syndrome	1.4%
206	Dermatomyositis	1.3%
207	Muscular Dystrophy, Duchenne	1.3%
208	Porencephaly	1.3%
209	Holoprosencephaly	1.2%
210	Familial Hypophosphatemic Rickets	1.1%
211	Radicular Cyst	0.8%
212	MELAS Syndrome	0.6%
213	Kearns-Sayre syndrome	0.6%

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