MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Bone Diseases, Endocrine

(UMLS:C0005942)

Definition:: Diseases of the bones related to hyperfunction or hypofunction of the endocrine glands.
UMLS ID:: C0005942
MeSH ID:: D001849

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.132

Classification 2:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.149

Synonym(s)

Bone Diseases, Endocrine

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Calcitriol		3626302	CTD
2	Vitamin D		16608887	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Bone Diseases, Developmental	30%
2	Hyperostosis	30%
3	Osteitis	30%
4	Osteitis Deformans	30%
5	Osteochondrosis	30%
6	Spinal Diseases	30%
7	Osteoarthropathy, Secondary Hypertrophic	29.6%
8	Dwarfism	25.4%
9	Spinal Neoplasms	25.4%
10	Spondylitis	25.4%
11	Platybasia	24.3%
12	Osteochondritis	23.2%
13	Bone Diseases, Infectious	22.2%
14	Bone neoplasms	22.2%
15	Osteopenia	22.2%
16	Ainhum	22%
17	Dysostoses	22%
18	Spinal Stenosis	22%
19	Spondylosis	22%
20	Intervertebral Disc Degeneration	22%
21	Bone Resorption	21.8%
22	Aseptic Necrosis of Bone	21.8%
23	Adrenal Gland Diseases	21.1%
24	Gonadal Disorders	21.1%
25	Parathyroid Diseases	21.1%
26	Thyroid Diseases	21.1%
27	Discitis	20.7%
28	Gigantism	19.7%
29	Pectus excavatum	18.6%
30	Congenital Hypothyroidism	18.4%
31	Chondrodysplasia Punctata	18.1%
32	Enchondromatosis	18.1%
33	Lordosis	18.1%
34	Osteosclerosis	18.1%
35	Spondylolysis	18.1%
36	kyphosis	18.1%
37	Kashin-Beck Disease	18.1%
38	Adrenal Gland Neoplasms	17.4%
39	Pectus carinatum	17.2%
40	Tuberculosis, Spinal	17%
41	Osteoarthritis, Spine	16.8%
42	Multiple Epiphyseal Dysplasia	16.4%
43	Osteochondrodysplasias	16.4%
44	Klippel-Feil Syndrome	16.3%
45	Synostosis	16.3%
46	Melorheostosis	16.2%
47	Osteopetrosis	16.2%
48	Spondylolisthesis	16.2%
49	Spondylarthropathies	16.2%
50	Osteomyelitis	16.1%
51	Osteoporosis	16.1%
52	Periostitis	16.1%
53	Bone Demineralization, Pathologic	16.1%
54	Post-Traumatic Osteoporosis	16.1%
55	Ankylosing spondylitis	16%
56	Alveolar Bone Loss	15.9%
57	Femur Head Necrosis	15.9%
58	Osteolysis	15.9%
59	Fasciitis	15.8%
60	Foot Deformities	15.8%
61	Arthropathy	15.8%
62	Endocrine Gland Neoplasms	15.4%
63	Diabetes Mellitus	15.1%
64	Adrenal Cortex Diseases	15%
65	Euthyroid Sick Syndromes	15%
66	Goiter	15%
67	Hyperparathyroidism	15%
68	Hyperthyroidism	15%
69	Hyperthyroxinemia	15%
70	Hypogonadism	15%
71	Hypoparathyroidism	15%
72	Hypothyroidism	15%
73	Delayed Puberty	15%
74	Precocious Puberty	15%
75	Thyroiditis	15%
76	Hypogonadotropic hypogonadism	15%
77	Testotoxicosis	15%
78	Secondary hypothyroidism	15%
79	Primary Hyperthyroidism	15%
80	Primary Hypothyroidism	15%
81	Pituitary Diseases	15%
82	Contracture	14.8%
83	Fasciitis, Plantar	14.8%
84	Craniofacial Dysostosis	14.6%
85	Arthrogryposis	14.5%
86	Parathyroid Neoplasms	14.3%
87	Thyroid Neoplasm	14.3%
88	Thyroid carcinoma	14.3%
89	Arthritis, Psoriatic	13.2%
90	Osteoporosis, Postmenopausal	13.2%
91	Adrenocortical carcinoma	13%
92	Arthritis, Reactive	12.6%
93	Joint Tuberculosis	12.5%
94	Tuberculosis, Osteoarticular	12.5%
95	Bone Tuberculosis	12.5%
96	Acrocephalosyndactylia	12.4%
97	Craniosynostosis	12.4%
98	Syndactyly	12.4%
99	Brachycephaly	12.4%
100	Cushing Syndrome	12.2%
101	Hyperaldosteronism	12.2%
102	Hyperparathyroidism, Secondary	12.2%
103	Hypoaldosteronism	12.2%
104	Thyrotoxicosis	12.2%
105	Hyperparathyroidism, Primary	12.2%
106	Thyroid Hormone Resistance Syndrome	12.2%
107	Jaw Diseases	12%
108	Eosinophilic Granuloma	11.8%
109	Graves Disease	11.8%
110	Goldenhar Syndrome	11.7%
111	Fibromyalgia	11.6%
112	Polymyalgia Rheumatica	11.6%
113	Cartilage Diseases	11.5%
114	Foot Diseases	11.5%
115	Myopathy	11.5%
116	Rheumatism	11.5%
117	Chondromalacia	11.5%
118	Metatarsalgia	11.5%
119	Thyroid Nodule	11.5%
120	Testicular Diseases	11.1%
121	Poland Syndrome	10.9%
122	ovarian neoplasm	10.9%
123	Hyperglycemic Hyperosmolar Nonketotic Coma	10.8%
124	Hashimoto Disease	10.8%
125	Ovarian Diseases	10.8%
126	Empty Sella Syndrome	10.8%
127	Hyperpituitarism	10.8%
128	Hypopituitarism	10.8%
129	Hypophysitis	10.8%
130	Hip Contracture	10.7%
131	Periarthritis	10.7%
132	Osteogenesis Imperfecta	10.6%
133	Mandibulofacial Dysostosis	10.5%
134	Ischemic contracture	10.5%
135	Rickets	10.4%
136	Mastoiditis	10.3%
137	Petrositis	10.3%
138	Diabetic Foot	10.3%
139	Nelson Syndrome	10.1%
140	Arthritis	10%
141	Bursitis	10%
142	Joint Instability	10%
143	Myofascial Pain Syndromes	10%
144	Rhabdomyolysis	10%
145	Synovitis	10%
146	Joint laxity	10%
147	Polyarthritis	10%
148	Frozen shoulder	10%
149	Patellofemoral Pain Syndrome	10%
150	Rheumatic Fever	9.9%
151	Gout	9.9%
152	Osteoarthritis, Knee	9.7%
153	Prolactinoma	9.7%
154	Growth Hormone-Secreting Pituitary Adenoma	9.7%
155	Temporomandibular Joint Disorders	9.7%
156	Testicular Neoplasms	9.5%
157	Antley-Bixler Syndrome Phenotype	9.4%
158	Talipes	9.4%
159	Temporomandibular Joint Dysfunction Syndrome	9.2%
160	Addison Disease	9.1%
161	Diabetic Angiopathies	9.1%
162	Autoimmune thyroiditis	9.1%
163	Primary Adrenal Insufficiency	9.1%
164	Diabetic Neuropathies	8.9%
165	Myxedema	8.9%
166	Orchitis	8.9%
167	Diabetic Amyotrophy	8.9%
168	Diabetic Autonomic Neuropathy	8.9%
169	Diabetic Cardiomyopathies	8.9%
170	Renal Osteodystrophy	8.9%
171	Renal rickets	8.9%
172	Pseudohypoparathyroidism	8.8%
173	Ovarian Hyperstimulation Syndrome	8.8%
174	Hyperprolactinemia	8.8%
175	Gestational Diabetes	8.6%
176	Latent Autoimmune Diabetes in Adults	8.6%
177	Diabetes Insipidus	8.5%
178	Diabetes Mellitus, Experimental	8.5%
179	Osteomalacia	8.5%
180	Rheumatoid Arthritis	8.3%
181	Juvenile arthritis	8.3%
182	Palatal Neoplasms	8.3%
183	Pituitary Adenoma	8.1%
184	Pituitary Neoplasms	8.1%
185	Kallmann Syndrome	8.1%
186	Congenital clubfoot	8%
187	Vertical Talus	8%
188	granulosa cell tumor	8%
189	Carcinoma, Ovarian Epithelial	8%
190	Rubinstein-Taybi Syndrome	7.9%
191	Arthritis, Gouty	7.7%
192	Rheumatoid Nodule	7.6%
193	Compartment syndromes	7.4%
194	Maxillary Diseases	7.4%
195	Tendinitis	7.4%
196	Tendinopathy	7.4%
197	Bunion	7.3%
198	Fibrodysplasia Ossificans Progressiva	7.3%
199	Myoglobinuria	7.3%
200	Myositis Ossificans	7.3%
201	Tenosynovitis	7.3%
202	Sacroiliitis	7.3%
203	Hemarthrosis	7.3%
204	Myositis	7.3%
205	Tietze's Syndrome	7.3%
206	Limb Deformities, Congenital	7.3%
207	Isaacs syndrome	7.3%
208	Craniofacial Abnormalities	7.3%
209	Myotonic Disorders	7.3%
210	Hermaphroditism	7.1%
211	Disorders of Sex Development	7.1%
212	Corpus Luteum Cyst	7.1%
213	Ovarian Cysts	7.1%
214	Basal Cell Nevus Syndrome	7%
215	Klinefelter Syndrome	7%
216	Diabetic Nephropathy	7%
217	Acromegaly	7%
218	Marfan Syndrome	6.9%
219	Anovulation	6.9%
220	Diabetic Ketoacidosis	6.9%
221	Oophoritis	6.9%
222	Pituitary Apoplexy	6.9%
223	Cockayne Syndrome	6.4%
224	Leydig Cell Tumor	6.4%
225	Diabetic Retinopathy	6.4%
226	Felty Syndrome	6.3%
227	Polycystic Ovary Syndrome	6.2%
228	Multiple Endocrine Neoplasia	6.1%
229	Pancreatic Neoplasm	6.1%
230	Hyperandrogenism	6%
231	Cryptorchidism	5.9%
232	Nose Neoplasms	5.8%
233	Medial Tibial Stress Syndrome	5.8%
234	Gonadal Dysgenesis	5.7%
235	Adrenogenital Syndrome	5.7%
236	Ovotesticular Disorders of Sex Development	5.7%
237	Mitochondrial Myopathies	5.7%
238	Muscle Cramp	5.7%
239	Eosinophilia-Myalgia Syndrome	5.7%
240	Gastroschisis	5.7%
241	Jaw Abnormalities	5.6%
242	Muscle Rigidity	5.6%
243	Muscle Spasticity	5.6%
244	Cogwheel Rigidity	5.6%
245	Nuchal Rigidity	5.6%
246	Prognathism	5.5%
247	Arthritis, Infectious	5.5%
248	Rheumatoid Vasculitis	5.4%
249	Anterior Compartment Syndrome	5.4%
250	Enthesopathy	5.4%
251	Arthritis, Experimental	5.4%
252	Abdominal Compartment Syndrome	5.4%
253	Amelia	5.3%
254	Arachnodactyly	5.3%
255	Ectromelia	5.3%
256	Hemimelia	5.3%
257	Phocomelia	5.3%
258	Sirenomelia	5.3%
259	Polymyositis	5.3%
260	Polydactyly	5.3%
261	Brachydactyly	5.3%
262	Plagiocephaly	5.3%
263	Lower Extremity Deformities, Congenital	5.3%
264	Upper Extremity Deformities, Congenital	5.3%
265	Chronic Fatigue Syndrome	4.9%
266	Multiple Endocrine Neoplasia Type 1	4.9%
267	Nail-Patella Syndrome	4.8%
268	Giant Cell Epulis	4.7%
269	Muscle Weakness	4.7%
270	Sicca Syndrome	4.7%
271	Sjogren's Syndrome	4.7%
272	Musculoskeletal Pain	4.7%
273	Familial Periodic Paralysis	4.7%
274	Arthralgia	4.6%
275	Polyarthralgia	4.6%
276	Micrognathism	4.4%
277	Pierre Robin Syndrome	4.4%
278	Hip Dislocation	4.3%
279	Shoulder Dislocation	4.3%
280	Hip Dysplasia	4.3%
281	Muscular Dystrophy	4.3%
282	Orbital Myositis	4.3%
283	Dupuytren Contracture	4.2%
284	Pyomyositis	4.2%
285	Myotonic Dystrophy	4.1%
286	Laryngomalacia	4.1%
287	Turner Syndrome	3.9%
288	Myalgia	3.9%
289	Retrognathia	3.9%
290	insulinoma	3.8%
291	Gastrinoma	3.8%
292	Glucagonoma	3.8%
293	Carcinoma, Pancreatic Ductal	3.7%
294	Carcinoma, Endometrioid	3.7%
295	Maxillofacial Abnormalities	3.5%
296	Myotonia Congenita	3.5%
297	Welander Distal Myopathy	3.5%
298	Bronchomalacia	3.4%
299	Tracheomalacia	3.4%
300	Microcephaly	3.4%
301	Macrocephaly	3.4%
302	Hypokalemic periodic paralysis	3.4%
303	Shoulder Pain	3.4%
304	Vipoma	3.3%
305	Cleft Palate	3.2%
306	Familial Hypophosphatemic Rickets	3.1%
307	Waterhouse-Friderichsen Syndrome	3%
308	Dermatomyositis	2.9%
309	Mitochondrial Encephalomyopathies	2.9%
310	Muscular Dystrophy, Duchenne	2.9%
311	Porencephaly	2.8%
312	Noonan Syndrome	2.6%
313	Holoprosencephaly	2.3%
314	Radicular Cyst	2.2%
315	Denys-Drash Syndrome	2.1%
316	Adrenoleukodystrophy	1.8%
317	MELAS Syndrome	1.5%
318	Kearns-Sayre syndrome	1.4%

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