MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Femur Head Necrosis

(UMLS:C0015814)

Definition:: Aseptic or avascular necrosis of the femoral head. The major types are idiopathic (primary), as a complication of fractures or dislocations, and LEGG-CALVE-PERTHES DISEASE.
UMLS ID:: C0015814
MeSH ID:: D005271

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.852.175

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.717.732.368

Synonym(s)

Femur Head Necrosis

FEMUR HEAD NECROSIS

femur head necrosis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Dexamethasone	30506661	CTD
2	Methylprednisolone	30878453	CTD
3	Tretinoin	10609785	CTD
4	fludarabine	30506661	CTD
5	naringin	30878453	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Infarction	24.8%
2	Fat necrosis	23.1%
3	Gangrene	23.1%
4	Osteoarthropathy, Secondary Hypertrophic	20.5%
5	Bone Diseases, Developmental	20.2%
6	Hyperostosis	20.2%
7	Osteitis	20.2%
8	Osteitis Deformans	20.2%
9	Osteochondrosis	20.2%
10	Spinal Diseases	20.2%
11	Dental Pulp Necrosis	17.4%
12	Polydipsia	17.1%
13	Ascites	16.9%
14	Fibrosis	16.9%
15	Gliosis	16.9%
16	Growth Disorders	16.9%
17	Hemorrhage	16.9%
18	Hyperbilirubinemia	16.9%
19	Hyperplasia	16.9%
20	Hypomenorrhea	16.9%
21	Inflammation	16.9%
22	Intraoperative Complications	16.9%
23	Ischemia	16.9%
24	Lithiasis	16.9%
25	Malacoplakia	16.9%
26	Menstruation Disturbances	16.9%
27	Metaplasia	16.9%
28	Nerve Degeneration	16.9%
29	Ochronosis	16.9%
30	Polymenorrhea	16.9%
31	Postoperative Complications	16.9%
32	Sclerosis	16.9%
33	Shock	16.9%
34	Ulcer	16.9%
35	Hyperammonemia	16.9%
36	Hyperamylasemia	16.9%
37	Teratogenesis	16.9%
38	Cardiac Death	16.9%
39	Hypovolemia	16.9%
40	Hyperuricemia	16.9%
41	Leukoaraiosis	16.9%
42	Dysbacteriosis	16.9%
43	Delayed Graft Function	16.9%
44	Cirrhosis	16.9%
45	Neointima	16.9%
46	Dysbiosis	16.9%
47	Osteochondritis	16.3%
48	Bone Diseases, Endocrine	15.9%
49	Gigantism	15.9%
50	Spinal Neoplasms	15.9%
51	Spondylitis	15.9%
52	Bone Diseases, Infectious	15.4%
53	Bone neoplasms	15.4%
54	Osteopenia	15.4%
55	Platybasia	15.4%
56	Bone Resorption	15.1%
57	Postoperative Hemorrhage	14.9%
58	Shock, Hemorrhagic	14.9%
59	Systemic Inflammatory Response Syndrome	14.9%
60	DNA Degradation, Necrotic	14.1%
61	Vascular Remodeling	13.8%
62	Extravasation of Diagnostic and Therapeutic Materials	13.3%
63	Neoplastic Processes	13.3%
64	Ainhum	13.2%
65	Dysostoses	13.2%
66	Spinal Stenosis	13.2%
67	Spondylosis	13.2%
68	Intervertebral Disc Degeneration	13.2%
69	Muscle Weakness	12.9%
70	Granulomatosis, Orofacial	12.8%
71	Pigmentation Disorders	12.8%
72	Respiratory Aspiration	12.8%
73	Eosinophilic Granuloma	12.7%
74	Acantholysis	12.6%
75	Chromosome Aberrations	12.6%
76	Dehydration	12.6%
77	Granuloma	12.6%
78	Hemarthrosis	12.6%
79	Leukocytosis	12.6%
80	Pleocytosis	12.6%
81	Pectus excavatum	12.1%
82	Fasciitis	11.8%
83	Foot Deformities	11.8%
84	Arthropathy	11.8%
85	Discitis	11.7%
86	Pectus carinatum	11.6%
87	Signs and Symptoms	10.6%
88	Pathological Conditions, Anatomical	10.6%
89	Genomic Instability	10.5%
90	Arthrogryposis	10.3%
91	Contracture	10.3%
92	Fasciitis, Plantar	10.3%
93	Multiple Epiphyseal Dysplasia	10.1%
94	Osteochondrodysplasias	10.1%
95	Congenital Hypothyroidism	10%
96	Klippel-Feil Syndrome	10%
97	Synostosis	10%
98	Chromosomal Instability	10%
99	Osteomyelitis	9.9%
100	Osteoporosis	9.9%
101	Periostitis	9.9%
102	Bone Demineralization, Pathologic	9.9%
103	Incisional hernia	9.9%
104	Post-Traumatic Osteoporosis	9.9%
105	jaundice	9.9%
106	Azotemia	9.9%
107	Acute Disease	9.9%
108	Acute-Phase Reaction	9.9%
109	Amenorrhea	9.9%
110	Chronic disease	9.9%
111	Critical Illness	9.9%
112	Sudden death	9.9%
113	Graft Occlusion, Vascular	9.9%
114	Granuloma, Plasma Cell	9.9%
115	Hematoma	9.9%
116	Iatrogenic Disease	9.9%
117	Multiple Organ Failure	9.9%
118	Oligomenorrhea	9.9%
119	Premenstrual syndrome	9.9%
120	Recurrence	9.9%
121	Retrograde Degeneration	9.9%
122	Retroperitoneal fibrosis	9.9%
123	Serositis	9.9%
124	Subcutaneous Emphysema	9.9%
125	Surgical Wound Dehiscence	9.9%
126	Syndrome	9.9%
127	Wallerian Degeneration	9.9%
128	Pyogenic granuloma	9.9%
129	Exsanguination	9.9%
130	Disease Progression	9.9%
131	Seroma	9.9%
132	Premenstrual Tension	9.9%
133	Delayed Emergence from Anesthesia	9.9%
134	Infant Death	9.9%
135	Anastomotic Leak	9.9%
136	Intraoperative Awareness	9.9%
137	Alveolar Bone Loss	9.8%
138	Osteolysis	9.8%
139	Chondrodysplasia Punctata	9.8%
140	Enchondromatosis	9.8%
141	Lordosis	9.8%
142	Osteosclerosis	9.8%
143	Spondylolysis	9.8%
144	kyphosis	9.8%
145	Kashin-Beck Disease	9.8%
146	Menorrhagia	9.8%
147	Sudden infant death syndrome	9.8%
148	Tuberculosis, Spinal	9.7%
149	Osteoarthritis, Spine	9.5%
150	Metatarsalgia	9.5%
151	Jaw Diseases	9.2%
152	Pain, Postoperative	9%
153	Cartilage Diseases	8.8%
154	Foot Diseases	8.8%
155	Myopathy	8.8%
156	Rheumatism	8.8%
157	Chondromalacia	8.8%
158	Ankylosing spondylitis	8.6%
159	Dysmenorrhea	8.6%
160	Failed Back Surgery Syndrome	8.6%
161	Cardiotoxicity	8.5%
162	Spondylarthropathies	8.5%
163	Craniofacial Dysostosis	8.5%
164	Postoperative Nausea and Vomiting	8.5%
165	Giant Cell Epulis	8.4%
166	Dwarfism	8.4%
167	Eye Hemorrhage	8.3%
168	Fibromyalgia	8.2%
169	Polymyalgia Rheumatica	8.2%
170	Melorheostosis	8.1%
171	Osteopetrosis	8.1%
172	Spondylolisthesis	8.1%
173	Hemoptysis	8.1%
174	Ecchymosis	7.9%
175	Petechiae	7.9%
176	Purpura	7.9%
177	Acromegaly	7.9%
178	Joint Tuberculosis	7.9%
179	Tuberculosis, Osteoarticular	7.9%
180	Bone Tuberculosis	7.9%
181	Asphyxia	7.8%
182	Granuloma, Respiratory Tract	7.8%
183	Shock, Traumatic	7.8%
184	Disease susceptibility	7.6%
185	Fetal Death	7.6%
186	Foreign-Body Reaction	7.6%
187	Gastrointestinal Hemorrhage	7.6%
188	Hemoperitoneum	7.6%
189	Hemothorax	7.6%
190	Neoplasm Invasiveness	7.6%
191	Neoplasm Metastasis	7.6%
192	Neoplasm Recurrence, Local	7.6%
193	Postpericardiotomy Syndrome	7.6%
194	Prosthesis Failure	7.6%
195	Reperfusion Injury	7.6%
196	Injection Site Reaction	7.6%
197	Retrobulbar Hemorrhage	7.6%
198	Peritoneal Fibrosis	7.6%
199	Carcinogenesis	7.6%
200	Neurogenic Inflammation	7.6%
201	Perinatal death	7.6%
202	Infusion site reaction	7.6%
203	Nephrogenic Fibrosing Dermopathy	7.6%
204	Corneal Endothelial Cell Loss	7.6%
205	Encapsulating Peritoneal Sclerosis	7.6%
206	Vasoplegia	7.6%
207	Suppuration	7.6%
208	Nephrogenic Systemic Fibrosis	7.6%
209	Metastasis	7.6%
210	Sinus Arrhythmia	7.4%
211	Atrial Fibrillation	7.4%
212	Atrial Flutter	7.4%
213	Granuloma, Foreign-Body	7.4%
214	Mediastinal Emphysema	7.4%
215	Surgical Wound Infection	7.4%
216	Ventricular Fibrillation	7.4%
217	Ventricular Flutter	7.4%
218	Parasystole	7.4%
219	Paroxysmal atrial fibrillation	7.4%
220	Facies	7.4%
221	Bradycardia	7.4%
222	Embryo Loss	7.4%
223	Afferent Loop Syndrome	7.4%
224	Sex Chromosome Aberrations	7.4%
225	Short Bowel Syndrome	7.4%
226	Uterine hemorrhage	7.4%
227	No-Reflow Phenomenon	7.4%
228	Osteoporosis, Postmenopausal	7.3%
229	Craniosynostosis	7.2%
230	Syndactyly	7.2%
231	Brachycephaly	7.2%
232	Arthritis, Psoriatic	7.2%
233	Endotoxic shock	6.8%
234	Septic Shock	6.8%
235	Toxic Shock Syndrome	6.8%
236	Acrocephalosyndactylia	6.8%
237	Epistaxis	6.8%
238	Arthritis	6.7%
239	Bursitis	6.7%
240	Joint Instability	6.7%
241	Myofascial Pain Syndromes	6.7%
242	Rhabdomyolysis	6.7%
243	Synovitis	6.7%
244	Joint laxity	6.7%
245	Polyarthritis	6.7%
246	Frozen shoulder	6.7%
247	Patellofemoral Pain Syndrome	6.7%
248	Rheumatic Fever	6.7%
249	Gout	6.6%
250	Ischemic contracture	6.6%
251	Arthritis, Reactive	6.6%
252	Hip Contracture	6.6%
253	Periarthritis	6.6%
254	Rickets	6.6%
255	Tissue Adhesions	6.5%
256	Hematoma, Epidural, Spinal	6.5%
257	Chromosome Fragility	6.5%
258	Jaundice, Obstructive	6.5%
259	Temporomandibular Joint Disorders	6.3%
260	Drowning	6.2%
261	Fetal Growth Retardation	6%
262	Aneuploidy	6%
263	Osteogenesis Imperfecta	6%
264	Polyploidy	6%
265	Microsatellite Instability	6%
266	Heart Block	6%
267	Tachycardia	6%
268	Tachyarrhythmia	6%
269	Cicatrix	6%
270	Goldenhar Syndrome	5.9%
271	Hematuria	5.9%
272	Granuloma Annulare	5.9%
273	Chromosome Breakage	5.9%
274	Brain Death	5.9%
275	Shock, Cardiogenic	5.9%
276	Poland Syndrome	5.9%
277	Mastoiditis	5.8%
278	Petrositis	5.8%
279	Osteoarthritis, Knee	5.7%
280	Talipes	5.7%
281	Mandibulofacial Dysostosis	5.7%
282	Rheumatoid Arthritis	5.6%
283	Juvenile arthritis	5.6%
284	Pseudohypoparathyroidism	5.6%
285	Asthenia	5.6%
286	Body Temperature Changes	5.6%
287	Calculi	5.6%
288	Cyanosis	5.6%
289	Edema	5.6%
290	Failure to Thrive	5.6%
291	Fatigue	5.6%
292	Feminization	5.6%
293	Fetal Distress	5.6%
294	Hernia	5.6%
295	Hypertrophy	5.6%
296	Motion Sickness	5.6%
297	Nails, Malformed	5.6%
298	polyps	5.6%
299	Rupture, Spontaneous	5.6%
300	Signs and Symptoms, Digestive	5.6%
301	Signs and Symptoms, Respiratory	5.6%
302	Skin Manifestations	5.6%
303	Chills	5.6%
304	Lassitude	5.6%
305	Enterocele	5.6%
306	Atheroma	5.6%
307	Pseudophakia	5.6%
308	Urological Manifestations	5.6%
309	Stenosis	5.6%
310	Facial asymmetry	5.6%
311	Mobility Limitation	5.6%
312	Somnolence	5.6%
313	Plaque, Amyloid	5.6%
314	Plaque, Atherosclerotic	5.6%
315	Sick Sinus Syndrome	5.6%
316	Temporomandibular Joint Dysfunction Syndrome	5.6%
317	Trisomy	5.6%
318	Antley-Bixler Syndrome Phenotype	5.3%
319	Muscle Cramp	5.3%
320	Gastroschisis	5.3%
321	Hematemesis	5.2%
322	Purpura Fulminans	5.2%
323	Compartment syndromes	5.1%
324	Maxillary Diseases	5.1%
325	Tendinitis	5.1%
326	Tendinopathy	5.1%
327	Myositis	5%
328	Tietze's Syndrome	5%
329	Limb Deformities, Congenital	5%
330	Isaacs syndrome	5%
331	Craniofacial Abnormalities	5%
332	Myotonic Disorders	5%
333	Cross Infection	5%
334	Hyphema	5%
335	Retinal Neovascularization	5%
336	Septicemia	5%
337	Vitreous Hemorrhage	5%
338	Sepsis	5%
339	Muscle Rigidity	5%
340	Muscle Spasticity	5%
341	Cogwheel Rigidity	5%
342	Nuchal Rigidity	5%
343	Long QT Syndrome	4.9%
344	Abscess	4.9%
345	Empyema	4.9%
346	Fetal Resorption	4.9%
347	Lymphatic Metastasis	4.9%
348	Neoplasms, Unknown Primary	4.9%
349	Peptic Ulcer Hemorrhage	4.9%
350	Sudden Cardiac Death	4.9%
351	Leukemic Infiltration	4.9%
352	Premenstrual Dysphoric Disorder	4.9%
353	Choroidal Neovascularization	4.9%
354	Primary Graft Dysfunction	4.9%
355	Neoplasm Micrometastasis	4.9%
356	Dumping Syndrome	4.9%
357	Cicatrix, Hypertrophic	4.9%
358	Sinus Arrest, Cardiac	4.9%
359	Micronuclei, Chromosome-Defective	4.9%
360	Hematoma, Subdural, Spinal	4.9%
361	Metrorrhagia	4.9%
362	Osteomalacia	4.8%
363	Hematoma, Subdural	4.8%
364	Hematoma, Epidural, Cranial	4.8%
365	Rubinstein-Taybi Syndrome	4.7%
366	Palatal Neoplasms	4.7%
367	Arthritis, Gouty	4.6%
368	Rheumatoid Nodule	4.6%
369	Marfan Syndrome	4.5%
370	Basal Cell Nevus Syndrome	4.5%
371	Musculoskeletal Pain	4.4%
372	Cyst	4.4%
373	Eye Manifestations	4.4%
374	Neurologic Manifestations	4.4%
375	Congenital clubfoot	4.4%
376	Vertical Talus	4.4%
377	Arthralgia	4.4%
378	Bunion	4.4%
379	Fibrodysplasia Ossificans Progressiva	4.4%
380	Myoglobinuria	4.4%
381	Myositis Ossificans	4.4%
382	Tenosynovitis	4.4%
383	Polyarthralgia	4.4%
384	Sacroiliitis	4.4%
385	Subacute Combined Degeneration	4.3%
386	Leukoplakia	4.3%
387	Cardiac Output, High	4.3%
388	Myocardial Stunning	4.3%
389	Reticulocytosis	4.3%
390	Low Cardiac Output Syndrome	4.3%
391	Airway Remodeling	4.3%
392	Ventricular Remodeling	4.2%
393	Alopecia	4.2%
394	Intermittent Claudication	4.2%
395	Androgenetic Alopecia	4.2%
396	Phantom pain	4.2%
397	Phantom Limb Pain	4.2%
398	Abdominal Pain	4.1%
399	Medial Tibial Stress Syndrome	4.1%
400	Retinal Hemorrhage	4.1%
401	Mitochondrial Myopathies	4%
402	Choroid Hemorrhage	4%
403	Melena	4%
404	Eosinophilia-Myalgia Syndrome	4%
405	Postpartum Hemorrhage	3.9%
406	Gingival Hemorrhage	3.9%
407	Keloid	3.9%
408	Monosomy	3.9%
409	Tetraploidy	3.9%
410	Stillbirth	3.9%
411	Adams-Stokes Syndrome	3.9%
412	Atrioventricular Block	3.9%
413	Bundle-Branch Block	3.9%
414	Atrial Premature Complexes	3.9%
415	Sinoatrial Block	3.9%
416	Tachycardia, Paroxysmal	3.9%
417	Supraventricular tachycardia	3.9%
418	Tachycardia, Ventricular	3.9%
419	Tachycardia, Reciprocating	3.9%
420	Subarachnoid Hemorrhage	3.9%
421	Cerebral Hemorrhage	3.9%
422	Viremia	3.9%
423	Parasitemia	3.9%
424	Renal Colic	3.8%
425	Felty Syndrome	3.8%
426	Thrombocytopenic purpura	3.8%
427	Kernicterus	3.7%
428	Jaw Abnormalities	3.7%
429	Purpura, Hyperglobulinemic	3.7%
430	Cockayne Syndrome	3.7%
431	Hematoma, Subdural, Intracranial	3.6%
432	Hematoma, Subdural, Chronic	3.6%
433	Hematoma, Subdural, Acute	3.6%
434	Myalgia	3.5%
435	Chronic Fatigue Syndrome	3.5%
436	Prognathism	3.4%
437	Hypergammaglobulinemia	3.4%
438	Nail-Patella Syndrome	3.4%
439	Nose Neoplasms	3.4%
440	Arthritis, Infectious	3.4%
441	Cellulitis	3.3%
442	Eye pain	3.3%
443	Familial Periodic Paralysis	3.3%
444	Diverticulum	3.3%
445	Diverticulosis	3.3%
446	Anterior Compartment Syndrome	3.3%
447	Enthesopathy	3.3%
448	Arthritis, Experimental	3.3%
449	Abdominal Compartment Syndrome	3.3%
450	Anorexia	3.3%
451	Anoxia	3.3%
452	Constipation	3.3%
453	Diarrhea	3.3%
454	Dyspepsia	3.3%
455	Eructation	3.3%
456	Fever	3.3%
457	Flatulence	3.3%
458	Flushing	3.3%
459	Halitosis	3.3%
460	Heartburn	3.3%
461	Diaphragmatic Hernia	3.3%
462	Hiccough	3.3%
463	Hypercalciuria	3.3%
464	Hypercapnia	3.3%
465	Hyperphagia	3.3%
466	Intestinal Polyps	3.3%
467	Nausea	3.3%
468	Pallor	3.3%
469	Psychophysiologic Disorders	3.3%
470	Splenomegaly	3.3%
471	Vomiting	3.3%
472	Hypocapnia	3.3%
473	Dyschezia	3.3%
474	Hypoxia	3.3%
475	Hyperoxia	3.3%
476	Lower Urinary Tract Symptoms	3.3%
477	Hypoxemia	3.3%
478	Urinoma	3.3%
479	Muscular Atrophy	3.3%
480	Amelia	3.3%
481	Arachnodactyly	3.3%
482	Ectromelia	3.3%
483	Hemimelia	3.3%
484	Phocomelia	3.3%
485	Sirenomelia	3.3%
486	Polymyositis	3.3%
487	Polydactyly	3.3%
488	Brachydactyly	3.3%
489	Plagiocephaly	3.3%
490	Lower Extremity Deformities, Congenital	3.3%
491	Upper Extremity Deformities, Congenital	3.3%
492	Rheumatoid Vasculitis	3.3%
493	Renal Osteodystrophy	3.2%
494	Renal rickets	3.2%
495	Romano-Ward Syndrome	3.2%
496	Bacteremia	3%
497	Cell Transformation, Viral	3%
498	Shoulder Pain	3%
499	Fungemia	3%
500	Laryngomalacia	2.9%
501	Granuloma, Laryngeal	2.9%
502	Tachycardia, Atrioventricular Nodal Reentry	2.9%
503	Tachycardia, Ectopic Atrial	2.9%
504	Tachycardia, Ectopic Junctional	2.9%
505	Sinus Tachycardia	2.9%
506	Torsades de Pointes	2.9%
507	Accelerated Idioventricular Rhythm	2.9%
508	Sicca Syndrome	2.9%
509	Sjogren's Syndrome	2.9%
510	Abdomen, Acute	2.8%
511	Myocardial Reperfusion Injury	2.8%
512	Purpura, Thrombotic Thrombocytopenic	2.8%
513	Hip Dislocation	2.7%
514	Shoulder Dislocation	2.7%
515	Hip Dysplasia	2.7%
516	Muscular Dystrophy	2.7%
517	Orbital Myositis	2.7%
518	Dupuytren Contracture	2.7%
519	Micrognathism	2.6%
520	Pierre Robin Syndrome	2.6%
521	Pyomyositis	2.6%
522	Respiratory Tract Fistula	2.6%
523	Myotonic Dystrophy	2.6%
524	Apnea	2.5%
525	Cheyne-Stokes Respiration	2.5%
526	Decerebrate State	2.5%
527	Dyspnea	2.5%
528	Cardiomegaly	2.5%
529	Hemiparesis	2.5%
530	Hepatomegaly	2.5%
531	Hyperventilation	2.5%
532	Meningism	2.5%
533	Mouth Breathing	2.5%
534	Paresis	2.5%
535	Parovarian Cyst	2.5%
536	Pruritus	2.5%
537	Seizures	2.5%
538	Sensation Disorders	2.5%
539	Sneezing	2.5%
540	Spermatocele	2.5%
541	Erythema	2.5%
542	Oral Fistula	2.5%
543	Complex partial seizures	2.5%
544	Necrolytic Migratory Erythema	2.5%
545	Tachypnea	2.5%
546	Monoparesis	2.5%
547	Cutaneous Fistula	2.5%
548	Gait Disorders, Neurologic	2.5%
549	Neuromuscular Manifestations	2.5%
550	Cardiac Hypertrophy	2.5%
551	Edema, Cardiac	2.5%
552	Mental Fatigue	2.5%
553	Hirsutism	2.5%
554	Orthostatic intolerance	2.5%
555	Hypoventilation	2.5%
556	Vaginal Fistula	2.5%
557	Rectocele	2.5%
558	Body Weight Changes	2.4%
559	Endotoxemia	2.4%
560	Philadelphia Chromosome	2.4%
561	Waterhouse-Friderichsen Syndrome	2.3%
562	Retrognathia	2.3%
563	Body Weight	2.3%
564	Sarcopenia	2.3%
565	Maxillofacial Abnormalities	2.2%
566	Myotonia Congenita	2.2%
567	Autoimmune thrombocytopenia	2.2%
568	Immune thrombocytopenic purpura	2.2%
569	Bronchomalacia	2.2%
570	Tracheomalacia	2.2%
571	Back Pain	2.2%
572	Bulimia	2.2%
573	Neck Pain	2.2%
574	Chest Pain	2.2%
575	Colonic Polyps	2.2%
576	Dizziness	2.2%
577	Dysuria	2.2%
578	Facial Pain	2.2%
579	Fever of Unknown Origin	2.2%
580	Flank Pain	2.2%
581	Headache	2.2%
582	Nocturia	2.2%
583	Pain, Intractable	2.2%
584	Pelvic Pain	2.2%
585	Snoring	2.2%
586	Chronic pain	2.2%
587	Lightheadedness	2.2%
588	Pain, Referred	2.2%
589	Prostatism	2.2%
590	Throbbing Headache	2.2%
591	Labor Pain	2.2%
592	Cancer Pain	2.2%
593	Nociceptive Pain	2.2%
594	Microcephaly	2.2%
595	Macrocephaly	2.2%
596	Hypokalemic periodic paralysis	2.2%
597	Sleep Wake Disorders	2.2%
598	Pupil Disorders	2.1%
599	Neurobehavioral Manifestations	2.1%
600	Hoarseness	2.1%
601	Nasal Polyps	2%
602	Pleural Rub	2%
603	Rales	2%
604	Respiratory Sounds	2%
605	Rhonchi	2%
606	Stridor	2%
607	Wheezing	2%
608	Asterixis	2%
609	Ballismus	2%
610	Vertigo	2%
611	Pain	2%
612	Livedo Reticularis	2%
613	Ache	2%
614	Meningocele	2%
615	Oliguria	2%
616	Polyuria	2%
617	Proteinuria	2%
618	Urinary Calculi	2%
619	Encephalocele	2%
620	Welander Distal Myopathy	2%
621	Underweight	1.9%
622	Overweight	1.9%
623	Cleft Palate	1.9%
624	Gait Ataxia	1.9%
625	Mitochondrial Encephalomyopathies	1.9%
626	Basal Ganglia Hemorrhage	1.8%
627	Candidemia	1.7%
628	Voice Disorders	1.7%
629	Voice Disturbance	1.7%
630	Familial Hypophosphatemic Rickets	1.7%
631	Gagging	1.7%
632	Dermatomyositis	1.7%
633	Biliary Fistula	1.7%
634	Gastric Fistula	1.7%
635	Congenital diaphragmatic hernia	1.7%
636	Morning Sickness	1.7%
637	Noonan Syndrome	1.7%
638	Leukoplakia, Oral	1.6%
639	Anosmia	1.6%
640	Ataxia	1.6%
641	Athetosis	1.6%
642	Catalepsy	1.6%
643	Dental Fistula	1.6%
644	Dystonia	1.6%
645	Hemiplegia	1.6%
646	Locked-In Syndrome	1.6%
647	Muscle Hypertonia	1.6%
648	Muscle hypotonia	1.6%
649	Myoclonus	1.6%
650	Myotonia	1.6%
651	Neuralgia	1.6%
652	Oroantral Fistula	1.6%
653	Paraplegia	1.6%
654	Pseudobulbar Palsy	1.6%
655	Quadriplegia	1.6%
656	Spasm	1.6%
657	Spastic Paraplegia	1.6%
658	Status Epilepticus	1.6%
659	Taste Disorders	1.6%
660	Tremor	1.6%
661	Monoplegia	1.6%
662	Hypokinesia	1.6%
663	Left Ventricular Hypertrophy	1.6%
664	Gastroparesis	1.6%
665	Right Ventricular Hypertrophy	1.6%
666	Paraparesis	1.6%
667	Bradykinesia	1.6%
668	Waxy flexibility	1.6%
669	Action Tremor	1.6%
670	Resting Tremor	1.6%
671	Dysosmia	1.6%
672	Quadriparesis	1.6%
673	Olfaction Disorders	1.6%
674	Myokymia	1.6%
675	Somatosensory Disorders	1.6%
676	Neuropathic pain	1.6%
677	Hyperkinesia	1.6%
678	Intention tremor	1.6%
679	Muscular Dystrophy, Duchenne	1.6%
680	Akathisia	1.6%
681	Restlessness	1.6%
682	Psychomotor Agitation	1.6%
683	Rectal Prolapse	1.6%
684	Uterine Prolapse	1.6%
685	Vaginal Prolapse	1.6%
686	Emaciation	1.6%
687	Low Back Pain	1.6%
688	Visceral Pain	1.6%
689	Weight Gain	1.6%
690	Porencephaly	1.6%
691	Vesicovaginal Fistula	1.6%
692	Gait Apraxia	1.5%
693	Putaminal Hemorrhage	1.5%
694	Holoprosencephaly	1.5%
695	Jet Lag Syndrome	1.4%
696	Reflex, Abnormal	1.4%
697	Hyporeflexia	1.4%
698	Hyperreflexia	1.4%
699	Birth Weight	1.4%
700	Vision Disorders	1.4%
701	Metamorphopsia	1.4%
702	Visual Impairment	1.4%
703	Bronchial Fistula	1.4%
704	Pancreatic Fistula	1.4%
705	Cachexia	1.3%
706	Anisocoria	1.3%
707	Confusion	1.3%
708	Facial paralysis	1.3%
709	Intestinal Fistula	1.3%
710	Lethargy	1.3%
711	Memory Disorders	1.3%
712	Perceptual Disorders	1.3%
713	Psychomotor Disorders	1.3%
714	Tonic Pupil	1.3%
715	Anhedonia	1.3%
716	Disorientation	1.3%
717	Enterocutaneous Fistula	1.3%
718	Fetal Hypoxia	1.3%
719	Facial Paresis	1.3%
720	Memory Loss	1.3%
721	Hemisensory Neglect	1.3%
722	Dysacusis	1.3%
723	Dyspnea, Paroxysmal	1.3%
724	Mastodynia	1.3%
725	Respiratory Paralysis	1.3%
726	Salivary Gland Fistula	1.3%
727	Chorea	1.3%
728	Cystocele	1.3%
729	Tetany	1.3%
730	Urinary Incontinence	1.3%
731	Breakthrough Pain	1.3%
732	Albuminuria	1.3%
733	Hemoglobinuria	1.3%
734	Umbilical hernia	1.2%
735	Toothache	1.2%
736	Hyperemesis Gravidarum	1.2%
737	Dysgeusia	1.2%
738	Formication	1.2%
739	Hyperalgesia	1.2%
740	Hyperesthesia	1.2%
741	Hypesthesia	1.2%
742	Language Disorders	1.2%
743	Numbness	1.2%
744	Paresthesia	1.2%
745	Paraparesis, Spastic	1.2%
746	Trismus	1.2%
747	Epilepsia Partialis Continua	1.2%
748	Hypogeusia	1.2%
749	Brown-Sequard Syndrome	1.2%
750	Lockjaw	1.2%
751	Allodynia	1.2%
752	Ageusia	1.2%
753	Alice in Wonderland Syndrome	1.2%
754	Radicular Cyst	1.2%
755	Alexia	1.1%
756	Dyslexia	1.1%
757	Kearns-Sayre syndrome	1.1%
758	Consciousness Disorders	1.1%
759	Mental Retardation	1.1%
760	Depressed Level of Consciousness	1.1%
761	Mental deficiency	1.1%
762	Intellectual Disability	1.1%
763	Catatonia	1.1%
764	Ophthalmoplegia	1.1%
765	External Ophthalmoplegia	1.1%
766	Aphonia	1.1%
767	Hydrops Fetalis	1.1%
768	Sleep Deprivation	1.1%
769	Dysphonia	1.1%
770	Cerebrospinal Fluid Otorrhea	1.1%
771	Cerebrospinal Fluid Rhinorrhea	1.1%
772	Fetal Weight	1.1%
773	Obesity	1.1%
774	Agraphia	1%
775	Anomia	1%
776	Cluttering	1%
777	Language Development Disorders	1%
778	Speech Disorders	1%
779	Syncope	1%
780	Stupor	1%
781	Dysgraphia	1%
782	Presyncope	1%
783	Dyslalia	1%
784	Diplopia	1%
785	Scotoma	1%
786	Photophobia	1%
787	Hemifacial Spasm	1%
788	Amaurosis	1%
789	Blindness	1%
790	Angina Pectoris	1%
791	Agnosia	1%
792	Apraxias	1%
793	Hallucinations	1%
794	Hemianopsia	1%
795	Hyperacusis	1%
796	Tinnitus	1%
797	Visual Agnosia	1%
798	Anosognosia	1%
799	Wernicke-Korsakoff Syndrome	1%
800	Phonophobia	1%
801	Hearing Loss	1%
802	Cerebellar Ataxia	1%
803	Torticollis	1%
804	Sciatica	1%
805	Urge Incontinence	1%
806	Tardive Dyskinesia	1%
807	Vocal Cord Paralysis	1%
808	Urinary Bladder Fistula	0.9%
809	Tinea Pedis	0.9%
810	Aphasia	0.9%
811	Articulation Disorders	0.9%
812	Echolalia	0.9%
813	Stuttering	0.9%
814	Dysphasia	0.9%
815	MELAS Syndrome	0.9%
816	Dysarthria	0.9%
817	Dyskinesia, Drug-Induced	0.8%
818	Amblyopia	0.8%
819	Amnesia	0.8%
820	Delirium	0.8%
821	Horner Syndrome	0.8%
822	Dissociative Amnesia	0.8%
823	Color blindness	0.8%
824	Global Amnesia	0.8%
825	Alcohol Withdrawal Seizures	0.8%
826	Arteriovenous fistula	0.8%
827	Rectal Fistula	0.8%
828	Anal Fistula	0.8%
829	Amaurosis Fugax	0.8%
830	Blindness, Cortical	0.8%
831	Dyscalculia	0.8%
832	Angina, Unstable	0.8%
833	Deafness	0.8%
834	Hearing Loss, Sudden	0.8%
835	Gerstmann Syndrome	0.8%
836	Hearing Loss, Bilateral	0.8%
837	Hearing Loss, High-Frequency	0.8%
838	Hearing Loss, Mixed Conductive-Sensorineural	0.8%
839	Prosopagnosia	0.8%
840	Apraxia, Ideomotor	0.8%
841	Persistent Vegetative State	0.8%
842	Charles Bonnet Syndrome	0.8%
843	Hearing Loss, Unilateral	0.8%
844	Complete Hearing Loss	0.8%
845	Alien Hand Syndrome	0.8%
846	Deaf Mutism	0.8%
847	Pediatric Obesity	0.8%
848	Mutism	0.7%
849	Selective Mutism	0.7%
850	Angina Pectoris, Variant	0.7%
851	Akathisia, Drug-Induced	0.7%
852	Kidney Calculi	0.7%
853	Ureteral Calculi	0.7%
854	Alexia, Pure	0.7%
855	Retrograde amnesia	0.7%
856	Amnesia, Anterograde	0.7%
857	Auditory Perceptual Disorders	0.6%
858	Amnesia, Transient Global	0.6%
859	Ophthalmoplegic Migraine	0.6%
860	Progressive supranuclear palsy	0.5%

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