MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fasciitis

(UMLS:C0015645)

Definition:: Inflammation of the fascia. There are three major types: 1, Eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, Necrotizing fasciitis (FASCIITIS, NECROTIZING), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, Nodular/Pseudosarcomatous /Proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma.
UMLS ID:: C0015645
MeSH ID:: D005208

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.321

Synonym(s)

Fasciitis

FASCIITIS

FASCIITIS, DIFFUSE

FASCITIS

Fasciitis, NOS

Fasciitis, unspecified

Fascitis

Inflammation of the fascia

diffuse; fasciitis

10.

fascia; inflammation

11.

fasciitis

12.

fasciitis; diffuse

13.

inflammation; fascia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 12		US FAERS
2	Ibuprofen	FAERS: 11		US FAERS
3	Docetaxel	FAERS: 5		US FAERS
4	Imatinib Mesylate	FAERS: 5		US FAERS
5	Canagliflozin	FAERS: 4		US FAERS
6	rofecoxib	FAERS: 4		OFFSIDES US FAERS
7	Letrozole	FAERS: 3		US FAERS
8	Levofloxacin	FAERS: 3		US FAERS
9	Norgestrel	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
10	Rivaroxaban	FAERS: 3		US FAERS
11	Rosuvastatin Calcium	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
12	Thyroxine	FAERS: 3		US FAERS
13	Cyclosporine	FAERS: 2		US FAERS
14	Diclofenac	FAERS: 2		US FAERS
15	Erlotinib Hydrochloride	FAERS: 2		US FAERS
16	Everolimus	FAERS: 2		US FAERS
17	Ezetimibe	FAERS: 2		US FAERS
18	Finasteride	FAERS: 2		US FAERS
19	Imatinib Mesylate	FAERS: 2		US FAERS
20	Methotrexate	FAERS: 2		US FAERS
21	Naltrexone	FAERS: 2		US FAERS
22	empagliflozin	FAERS: 2		US FAERS
23	pirfenidone	FAERS: 2		US FAERS
24	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 1		US FAERS
25	Acyclovir	FAERS: 1		US FAERS
26	Amoxicillin-Potassium Clavulanate Combination	FAERS: 1		US FAERS
27	Atorvastatin	FAERS: 1		US FAERS
28	Bortezomib	FAERS: 1		US FAERS
29	Cinacalcet	FAERS: 1		US FAERS
30	Ciprofloxacin	FAERS: 1		US FAERS
31	Clozapine	FAERS: 1		US FAERS
32	Daptomycin	FAERS: 1		US FAERS
33	Fingolimod Hydrochloride	FAERS: 1		US FAERS
34	Fluvastatin	FAERS: 1		US FAERS
35	Glatiramer Acetate	FAERS: 1		US FAERS
36	HhAntag691	FAERS: 1		US FAERS
37	Isotretinoin	FAERS: 1		US FAERS
38	Lenalidomide	FAERS: 1		US FAERS
39	Milnacipran	FAERS: 1		US FAERS
40	Octreotide	FAERS: 1		US FAERS
41	Omeprazole	FAERS: 1		US FAERS
42	Omeprazole	FAERS: 1		US FAERS
43	Ortho Evra	FAERS: 1		US FAERS
44	PCI 32765	FAERS: 1		US FAERS
45	Penicillin G benzathine and penicillin G procaine	FAERS: 1		US FAERS
46	Risperidone	FAERS: 1		US FAERS
47	Sulfasalazine	FAERS: 1		US FAERS
48	Sunitinib	FAERS: 1		US FAERS
49	Synjardy	FAERS: 1		US FAERS
50	Tacrolimus	FAERS: 1		US FAERS
51	Teriparatide	FAERS: 1		US FAERS
52	Triamcinolone	FAERS: 1		US FAERS
53	Vyxeos	FAERS: 1		US FAERS
54	Warfarin	FAERS: 1		US FAERS
55	apixaban	FAERS: 1		US FAERS
56	cabozantinib	FAERS: 1		US FAERS
57	fludarabine phosphate	FAERS: 1		US FAERS
58	gemcitabine	FAERS: 1		US FAERS
59	ramelteon	FAERS: 1		US FAERS
60	testosterone undecanoate	FAERS: 1		US FAERS
61	Beclomethasone			OFFSIDES
62	Beclomethasone			OFFSIDES
63	Clotrimazole			OFFSIDES
64	Dactinomycin			OFFSIDES
65	Goserelin			OFFSIDES
66	Imipramine	Canada Vigilance: 1		Canada Vigilance
67	Moclobemide			OFFSIDES
68	Nelfinavir			OFFSIDES
69	Pamidronate	Canada Vigilance: 1		Canada Vigilance
70	Penicillamine		9077501	CTD
71	Piperacillin			OFFSIDES
72	Povidone-Iodine			OFFSIDES
73	Pramipexole			SIDER
74	Ramipril		17351545	CTD
75	Temazepam			OFFSIDES
76	Tiotropium Bromide			OFFSIDES
77	Vinorelbine			OFFSIDES
78	cefditoren pivoxil			OFFSIDES
79	eletriptan			OFFSIDES
80	lamivudine, zidovudine drug combination			OFFSIDES
81	pirbuterol			OFFSIDES
82	posaconazole			SIDER
83	testosterone enanthate			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Bone Diseases	33.3%
2	Foot Deformities	33.3%
3	Arthropathy	33.3%
4	Contracture	30%
5	Osteoarthropathy, Secondary Hypertrophic	30%
6	Arthrogryposis	26.1%
7	Osteoarthritis, Spine	24.7%
8	Hip Contracture	23.8%
9	Periarthritis	23.8%
10	Arthritis	23.1%
11	Bone Diseases, Developmental	23.1%
12	Bursitis	23.1%
13	Hyperostosis	23.1%
14	Joint Instability	23.1%
15	Myofascial Pain Syndromes	23.1%
16	Osteitis	23.1%
17	Osteitis Deformans	23.1%
18	Osteochondrosis	23.1%
19	Rhabdomyolysis	23.1%
20	Spinal Diseases	23.1%
21	Synovitis	23.1%
22	Joint laxity	23.1%
23	Polyarthritis	23.1%
24	Frozen shoulder	23.1%
25	Patellofemoral Pain Syndrome	23.1%
26	Ankylosing spondylitis	22.8%
27	Osteoarthritis, Knee	22.4%
28	Jaw Diseases	22.2%
29	Fibromyalgia	21.8%
30	Osteochondritis	21.8%
31	Polymyalgia Rheumatica	21.8%
32	Metatarsalgia	21.6%
33	Cartilage Diseases	21.1%
34	Foot Diseases	21.1%
35	Myopathy	21.1%
36	Rheumatism	21.1%
37	Chondromalacia	21.1%
38	Ischemic contracture	20.8%
39	Platybasia	20.7%
40	Spondylarthropathies	20.2%
41	Pectus carinatum	20%
42	Pectus excavatum	19.6%
43	Rheumatic Fever	19.5%
44	Talipes	19.4%
45	Klippel-Feil Syndrome	18.6%
46	Synostosis	18.6%
47	Ainhum	18.5%
48	Bunion	18.5%
49	Dysostoses	18.5%
50	Fibrodysplasia Ossificans Progressiva	18.5%
51	Myoglobinuria	18.5%
52	Myositis Ossificans	18.5%
53	Spinal Stenosis	18.5%
54	Spondylosis	18.5%
55	Tenosynovitis	18.5%
56	Intervertebral Disc Degeneration	18.5%
57	Sacroiliitis	18.5%
58	Temporomandibular Joint Disorders	18.5%
59	Gout	18.4%
60	Temporomandibular Joint Dysfunction Syndrome	18.2%
61	Arthritis, Psoriatic	18%
62	Congenital clubfoot	17.5%
63	Gigantism	17.5%
64	Spinal Neoplasms	17.5%
65	Spondylitis	17.5%
66	Vertical Talus	17.5%
67	Arthritis, Reactive	17.4%
68	Craniofacial Dysostosis	16.4%
69	Rheumatoid Nodule	16.4%
70	Chondrodysplasia Punctata	16.4%
71	Enchondromatosis	16.4%
72	Lordosis	16.4%
73	Osteosclerosis	16.4%
74	Spondylolysis	16.4%
75	kyphosis	16.4%
76	Kashin-Beck Disease	16.4%
77	Craniosynostosis	16.1%
78	Syndactyly	16.1%
79	Brachycephaly	16.1%
80	Bone Diseases, Endocrine	15.8%
81	Rheumatoid Arthritis	15.7%
82	Juvenile arthritis	15.7%
83	Arthritis, Gouty	15.6%
84	Acrocephalosyndactylia	15.6%
85	Discitis	15.4%
86	Melorheostosis	15.3%
87	Osteopetrosis	15.3%
88	Spondylolisthesis	15.3%
89	Bone Diseases, Infectious	15%
90	Bone neoplasms	15%
91	Compartment syndromes	15%
92	Maxillary Diseases	15%
93	Osteopenia	15%
94	Tendinitis	15%
95	Fasciitis, Plantar	15%
96	Tendinopathy	15%
97	Bone Resorption	14.6%
98	Hemarthrosis	14.6%
99	Myositis	14.6%
100	Tietze's Syndrome	14.6%
101	Limb Deformities, Congenital	14.6%
102	Isaacs syndrome	14.6%
103	Craniofacial Abnormalities	14.6%
104	Aseptic Necrosis of Bone	14.6%
105	Myotonic Disorders	14.6%
106	Poland Syndrome	14.5%
107	Goldenhar Syndrome	14.1%
108	Felty Syndrome	13%
109	Arthritis, Infectious	12.2%
110	Multiple Epiphyseal Dysplasia	12.2%
111	Osteochondrodysplasias	12.2%
112	Tuberculosis, Spinal	12.1%
113	Anterior Compartment Syndrome	11.9%
114	Osteomyelitis	11.9%
115	Osteoporosis	11.9%
116	Periostitis	11.9%
117	Enthesopathy	11.9%
118	Bone Demineralization, Pathologic	11.9%
119	Post-Traumatic Osteoporosis	11.9%
120	Arthritis, Experimental	11.9%
121	Abdominal Compartment Syndrome	11.9%
122	Mandibulofacial Dysostosis	11.8%
123	Alveolar Bone Loss	11.8%
124	Amelia	11.8%
125	Arachnodactyly	11.8%
126	Ectromelia	11.8%
127	Femur Head Necrosis	11.8%
128	Hemimelia	11.8%
129	Phocomelia	11.8%
130	Sirenomelia	11.8%
131	Polymyositis	11.8%
132	Polydactyly	11.8%
133	Brachydactyly	11.8%
134	Plagiocephaly	11.8%
135	Lower Extremity Deformities, Congenital	11.8%
136	Upper Extremity Deformities, Congenital	11.8%
137	Osteolysis	11.8%
138	Congenital Hypothyroidism	11%
139	Medial Tibial Stress Syndrome	10.9%
140	Rheumatoid Vasculitis	10.7%
141	Mitochondrial Myopathies	10.7%
142	Muscle Cramp	10.6%
143	Eosinophilia-Myalgia Syndrome	10.6%
144	Gastroschisis	10.6%
145	Prognathism	10.6%
146	Muscle Rigidity	10.5%
147	Muscle Spasticity	10.5%
148	Cogwheel Rigidity	10.5%
149	Nuchal Rigidity	10.5%
150	Osteoporosis, Postmenopausal	10.5%
151	Antley-Bixler Syndrome Phenotype	10.4%
152	Jaw Abnormalities	10.3%
153	Dwarfism	9.4%
154	Sicca Syndrome	9.2%
155	Sjogren's Syndrome	9.2%
156	Hip Dislocation	9.1%
157	Shoulder Dislocation	9.1%
158	Hip Dysplasia	9.1%
159	Chronic Fatigue Syndrome	9%
160	Palatal Neoplasms	8.9%
161	Muscular Dystrophy	8.8%
162	Orbital Myositis	8.8%
163	Micrognathism	8.8%
164	Pierre Robin Syndrome	8.8%
165	Dupuytren Contracture	8.8%
166	Pyomyositis	8.7%
167	Acromegaly	8.6%
168	Joint Tuberculosis	8.6%
169	Tuberculosis, Osteoarticular	8.6%
170	Bone Tuberculosis	8.6%
171	Nail-Patella Syndrome	8.6%
172	Giant Cell Epulis	8.5%
173	Muscle Weakness	8.5%
174	Musculoskeletal Pain	8.4%
175	Familial Periodic Paralysis	8.3%
176	Arthralgia	8.3%
177	Polyarthralgia	8.3%
178	Rubinstein-Taybi Syndrome	8%
179	Myotonic Dystrophy	8%
180	Osteogenesis Imperfecta	8%
181	Welander Distal Myopathy	7.7%
182	Retrognathia	7.7%
183	Mastoiditis	7.7%
184	Petrositis	7.7%
185	Laryngomalacia	7.1%
186	Maxillofacial Abnormalities	7%
187	Myotonia Congenita	6.9%
188	Rickets	6.9%
189	Eosinophilic Granuloma	6.9%
190	Bronchomalacia	6.8%
191	Tracheomalacia	6.8%
192	Myalgia	6.8%
193	Microcephaly	6.8%
194	Macrocephaly	6.8%
195	Hypokalemic periodic paralysis	6.8%
196	Shoulder Pain	6.7%
197	Basal Cell Nevus Syndrome	6.4%
198	Dermatomyositis	6.3%
199	Cleft Palate	6.2%
200	Muscular Dystrophy, Duchenne	6.1%
201	Osteomalacia	6%
202	Porencephaly	6%
203	Pseudohypoparathyroidism	5.7%
204	Mitochondrial Encephalomyopathies	5.6%
205	Noonan Syndrome	4.9%
206	Radicular Cyst	4.7%
207	Cockayne Syndrome	4.4%
208	Marfan Syndrome	4.3%
209	Holoprosencephaly	4.2%
210	Nose Neoplasms	3.9%
211	Renal Osteodystrophy	3.7%
212	Renal rickets	3.7%
213	MELAS Syndrome	3%
214	Kearns-Sayre syndrome	2.7%
215	Familial Hypophosphatemic Rickets	2.1%

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