MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Polyarthritis

(UMLS:C0162323)

UMLS ID:: C0162323
MeSH ID:: D001168

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.114

Synonym(s)

Polyarthritis

ARTHRITIS, MULTIPLE JOINT INVOLVEMENT

Inflammatory arthritis of multiple joints

Inflammatory polyarthropathy

Inflammatory polyarthropathy, NOS

Inflammatory polyarthropathy, site unspecified

POLYARTHRITIS

Polyarthritis, NOS

Polyarthritis, unspecified

10.

Polyarticular Arthritis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Isotretinoin	FAERS: 51	US FAERS
2	Zoledronic Acid	FAERS: 23 Canada Vigilance: 1	Canada Vigilance US FAERS
3	Alendronate	FAERS: 21	US FAERS
4	Methimazole	FAERS: 18	US FAERS
5	rofecoxib	FAERS: 18	US FAERS
6	Minocycline	FAERS: 15 Canada Vigilance: 9	Canada Vigilance US FAERS
7	Ciprofloxacin	FAERS: 12	US FAERS
8	Norgestrel	FAERS: 12	US FAERS
9	Levofloxacin	FAERS: 10	US FAERS
10	Rivaroxaban	FAERS: 8	US FAERS
11	Clindamycin	FAERS: 7	US FAERS
12	Clopidogrel	FAERS: 7	US FAERS
13	Pregabalin	FAERS: 7 Canada Vigilance: 1	Canada Vigilance US FAERS
14	Rosuvastatin Calcium	FAERS: 7 Canada Vigilance: 1	Canada Vigilance US FAERS
15	Terbinafine	FAERS: 7	US FAERS
16	Alendronate	FAERS: 6	US FAERS
17	Moxifloxacin	FAERS: 6	US FAERS
18	Sitagliptin Phosphate	FAERS: 6 Canada Vigilance: 1	Canada Vigilance US FAERS
19	Teriparatide	FAERS: 6	US FAERS
20	Anastrozole	FAERS: 5	US FAERS
21	Dimethyl Fumarate	FAERS: 5	US FAERS
22	Minocycline	FAERS: 5 Canada Vigilance: 3	Canada Vigilance US FAERS
23	Ruxolitinib phosphate	FAERS: 5	US FAERS
24	Thyroxine	FAERS: 5	US FAERS
25	ambrisentan	FAERS: 5	US FAERS
26	tofacitinib	FAERS: 5	US FAERS
27	Carbamazepine	FAERS: 4	US FAERS
28	Cyclosporine	FAERS: 4	US FAERS
29	Methotrexate	FAERS: 4	US FAERS
30	Sevelamer	FAERS: 4	US FAERS
31	Varenicline	FAERS: 4	US FAERS
32	exemestane	FAERS: 4	US FAERS
33	Atorvastatin	FAERS: 3	US FAERS
34	Celecoxib	FAERS: 3	US FAERS
35	Estrogens, Conjugated (USP)	FAERS: 3	US FAERS
36	Lenalidomide	FAERS: 3	US FAERS
37	Linagliptin	FAERS: 3	US FAERS
38	Losartan	FAERS: 3	US FAERS
39	Methotrexate	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
40	Metoprolol	FAERS: 3	US FAERS
41	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 2 Canada Vigilance: 2	Canada Vigilance US FAERS
42	6-Chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide;3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;hydrochloride	FAERS: 2	US FAERS
43	Clindamycin	FAERS: 2	SIDER US FAERS
44	Clopidogrel	FAERS: 2	US FAERS
45	Clozapine	FAERS: 2	US FAERS
46	Dasatinib	FAERS: 2	US FAERS
47	Fenofibrate	FAERS: 2	US FAERS
48	Fingolimod Hydrochloride	FAERS: 2	US FAERS
49	Fluconazole	FAERS: 2	US FAERS
50	Imatinib Mesylate	FAERS: 2	US FAERS
51	Naproxen	FAERS: 2	US FAERS
52	Pravastatin	FAERS: 2	US FAERS
53	Risperidone	FAERS: 2	US FAERS
54	Sitagliptin Phosphate	FAERS: 2	US FAERS
55	Topiramate	FAERS: 2	US FAERS
56	Ursodeoxycholic Acid	FAERS: 2	US FAERS
57	etonogestrel	FAERS: 2	US FAERS
58	ledipasvir, sofosbuvir drug combination	FAERS: 2	US FAERS
59	palbociclib	FAERS: 2	US FAERS
60	teriflunomide	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
61	ziprasidone	FAERS: 2	US FAERS
62	2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
63	4-hydroxybutyric acid	FAERS: 1	US FAERS
64	5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydron;chloride	FAERS: 1	US FAERS
65	Amoxicillin-Potassium Clavulanate Combination	FAERS: 1	US FAERS
66	Amoxicillin	FAERS: 1	US FAERS
67	Arthrotec	FAERS: 1	US FAERS
68	Azacitidine	FAERS: 1	US FAERS
69	Benicar hct	FAERS: 1	US FAERS
70	Bosentan	FAERS: 1	US FAERS
71	Canagliflozin	FAERS: 1	US FAERS
72	Capecitabine	FAERS: 1	US FAERS
73	Ciprofloxacin	FAERS: 1	US FAERS
74	Cyclosporine	FAERS: 1	US FAERS
75	Deferiprone	FAERS: 1	US FAERS
76	Diclofenac	FAERS: 1	US FAERS
77	Dronedarone	FAERS: 1	US FAERS
78	Ezetimibe	FAERS: 1	US FAERS
79	Fluticasone-Salmeterol Drug Combination	FAERS: 1	US FAERS
80	Fluticasone	FAERS: 1	US FAERS
81	Glatiramer Acetate	FAERS: 1	US FAERS
82	Iloprost	FAERS: 1	US FAERS
83	Insulin Glargine	FAERS: 1	US FAERS
84	Leflunomide	FAERS: 1	US FAERS
85	Letrozole	FAERS: 1	US FAERS
86	Linezolid	FAERS: 1	US FAERS
87	Liraglutide	FAERS: 1	US FAERS
88	MDV 3100	FAERS: 1	US FAERS
89	Mirtazapine	FAERS: 1	US FAERS
90	Mycophenolic Acid	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
91	Norfloxacin	FAERS: 1	US FAERS
92	Olanzapine	FAERS: 1	US FAERS
93	Omeprazole	FAERS: 1	US FAERS
94	Ortho Evra	FAERS: 1	US FAERS
95	Oxcarbazepine	FAERS: 1	US FAERS
96	PCI 32765	FAERS: 1	US FAERS
97	Pamidronate	FAERS: 1	US FAERS
98	Penicillamine	FAERS: 1	US FAERS
99	Penicillin V	FAERS: 1	US FAERS
100	Phenytoin	FAERS: 1	US FAERS
101	Pravastatin	FAERS: 1	US FAERS
102	Raloxifene Hydrochloride	FAERS: 1	US FAERS
103	Rifabutin	FAERS: 1	US FAERS
104	Sorafenib	FAERS: 1	US FAERS
105	Sulfasalazine	FAERS: 1	US FAERS
106	Tamsulosin	FAERS: 1	US FAERS
107	Tenofovir	FAERS: 1	US FAERS
108	Trimethoprim, Sulfamethoxazole Drug Combination	FAERS: 1	US FAERS
109	Triprolidine	FAERS: 1	US FAERS
110	Triptorelin Pamoate	FAERS: 1	US FAERS
111	Valproic Acid	FAERS: 1	US FAERS
112	Valsartan	FAERS: 1	US FAERS
113	Vemurafenib	FAERS: 1	US FAERS
114	Vilazodone Hydrochloride	FAERS: 1	US FAERS
115	Warfarin	FAERS: 1	US FAERS
116	apixaban	FAERS: 1	US FAERS
117	apremilast	FAERS: 1	US FAERS
118	carfilzomib	FAERS: 1	US FAERS
119	cefditoren pivoxil	FAERS: 1	US FAERS
120	dolutegravir	FAERS: 1	US FAERS
121	eletriptan	FAERS: 1	US FAERS
122	eltrombopag	FAERS: 1	US FAERS
123	ferric gluconate	FAERS: 1	US FAERS
124	hydrochlorothiazide, losartan drug combination	FAERS: 1	US FAERS
125	ioversol	FAERS: 1	US FAERS
126	isoniazid, pyrazinamide, rifampin drug combination	FAERS: 1	US FAERS
127	ivacaftor	FAERS: 1	US FAERS
128	niraparib	FAERS: 1	US FAERS
129	olaparib	FAERS: 1	US FAERS
130	pimecrolimus	FAERS: 1	US FAERS
131	regorafenib	FAERS: 1	US FAERS
132	saxagliptin	FAERS: 1	US FAERS
133	telithromycin	FAERS: 1	US FAERS
134	valdecoxib	FAERS: 1	US FAERS
135	Aspirin	Canada Vigilance: 1	Canada Vigilance
136	Buprenorphine	Canada Vigilance: 1	Canada Vigilance
137	Nalidixic Acid	Canada Vigilance: 1	Canada Vigilance
138	Potassium;N-(2-carboxy-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-6-yl)-2-phenylethanimidate	Canada Vigilance: 1	Canada Vigilance
139	Prednisone	Canada Vigilance: 1	Canada Vigilance
140	Raltegravir Potassium		SIDER
141	Saquinavir		SIDER
142	Tacrolimus		SIDER
143	efavirenz		SIDER
144	paramethadione	Canada Vigilance: 1	Canada Vigilance
145	sitaxsentan		SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Bursitis	42.9%
2	Joint Instability	42.9%
3	Synovitis	42.9%
4	Joint laxity	42.9%
5	Frozen shoulder	42.9%
6	Patellofemoral Pain Syndrome	42.9%
7	Contracture	38.1%
8	Osteoarthropathy, Secondary Hypertrophic	38.1%
9	Arthrogryposis	28.2%
10	Hemarthrosis	27.9%
11	Metatarsalgia	27.8%
12	Hip Contracture	27.3%
13	Bone Diseases	23.1%
14	Fasciitis	23.1%
15	Foot Deformities	23.1%
16	Periarthritis	20.5%
17	Temporomandibular Joint Disorders	20.3%
18	Ischemic contracture	20.3%
19	Fasciitis, Plantar	19%
20	Ankylosing spondylitis	18.4%
21	Nail-Patella Syndrome	16.7%
22	Arthralgia	16.1%
23	Polyarthralgia	16.1%
24	Temporomandibular Joint Dysfunction Syndrome	16%
25	Hip Dislocation	15.8%
26	Jaw Diseases	15.8%
27	Shoulder Dislocation	15.8%
28	Hip Dysplasia	15.8%
29	Cartilage Diseases	15%
30	Foot Diseases	15%
31	Myopathy	15%
32	Rheumatism	15%
33	Chondromalacia	15%
34	Gout	14.6%
35	Bone Diseases, Developmental	14.3%
36	Hyperostosis	14.3%
37	Myofascial Pain Syndromes	14.3%
38	Osteitis	14.3%
39	Osteitis Deformans	14.3%
40	Osteochondrosis	14.3%
41	Rhabdomyolysis	14.3%
42	Spinal Diseases	14.3%
43	Fibromyalgia	14%
44	Osteochondritis	14%
45	Polymyalgia Rheumatica	14%
46	Pectus carinatum	12.6%
47	Platybasia	12.1%
48	Pectus excavatum	12.1%
49	Shoulder Pain	11.8%
50	Arthritis, Gouty	11.5%
51	Klippel-Feil Syndrome	11.1%
52	Synostosis	11.1%
53	Talipes	10.9%
54	Ainhum	10.3%
55	Bunion	10.3%
56	Dysostoses	10.3%
57	Fibrodysplasia Ossificans Progressiva	10.3%
58	Myoglobinuria	10.3%
59	Myositis Ossificans	10.3%
60	Spinal Stenosis	10.3%
61	Spondylosis	10.3%
62	Tenosynovitis	10.3%
63	Intervertebral Disc Degeneration	10.3%
64	Gigantism	10.2%
65	Spinal Neoplasms	10.2%
66	Spondylitis	10.2%
67	Bone Diseases, Endocrine	10%
68	Bone Diseases, Infectious	9.5%
69	Bone neoplasms	9.5%
70	Compartment syndromes	9.5%
71	Maxillary Diseases	9.5%
72	Osteopenia	9.5%
73	Tendinitis	9.5%
74	Tendinopathy	9.5%
75	Bone Resorption	9.3%
76	Myositis	9.3%
77	Tietze's Syndrome	9.3%
78	Limb Deformities, Congenital	9.3%
79	Isaacs syndrome	9.3%
80	Craniofacial Abnormalities	9.3%
81	Aseptic Necrosis of Bone	9.3%
82	Myotonic Disorders	9.3%
83	Congenital clubfoot	9.3%
84	Vertical Talus	9.3%
85	Craniofacial Dysostosis	9.2%
86	Craniosynostosis	9.1%
87	Syndactyly	9.1%
88	Brachycephaly	9.1%
89	Chondrodysplasia Punctata	8.5%
90	Enchondromatosis	8.5%
91	Lordosis	8.5%
92	Osteosclerosis	8.5%
93	Spondylolysis	8.5%
94	kyphosis	8.5%
95	Kashin-Beck Disease	8.5%
96	Acrocephalosyndactylia	8.3%
97	Discitis	8.3%
98	Poland Syndrome	7.7%
99	Melorheostosis	7.6%
100	Osteopetrosis	7.6%
101	Spondylolisthesis	7.6%
102	Goldenhar Syndrome	7.1%
103	Medial Tibial Stress Syndrome	7%
104	Multiple Epiphyseal Dysplasia	7%
105	Osteochondrodysplasias	7%
106	Osteoarthritis, Spine	6.9%
107	Mitochondrial Myopathies	6.9%
108	Muscle Cramp	6.8%
109	Rheumatic Fever	6.8%
110	Eosinophilia-Myalgia Syndrome	6.8%
111	Gastroschisis	6.8%
112	Anterior Compartment Syndrome	6.8%
113	Osteomyelitis	6.8%
114	Osteoporosis	6.8%
115	Periostitis	6.8%
116	Enthesopathy	6.8%
117	Bone Demineralization, Pathologic	6.8%
118	Post-Traumatic Osteoporosis	6.8%
119	Abdominal Compartment Syndrome	6.8%
120	Muscle Rigidity	6.8%
121	Muscle Spasticity	6.8%
122	Cogwheel Rigidity	6.8%
123	Nuchal Rigidity	6.8%
124	Alveolar Bone Loss	6.7%
125	Amelia	6.7%
126	Arachnodactyly	6.7%
127	Ectromelia	6.7%
128	Femur Head Necrosis	6.7%
129	Hemimelia	6.7%
130	Phocomelia	6.7%
131	Sirenomelia	6.7%
132	Polymyositis	6.7%
133	Polydactyly	6.7%
134	Brachydactyly	6.7%
135	Plagiocephaly	6.7%
136	Osteoarthritis, Knee	6.7%
137	Lower Extremity Deformities, Congenital	6.7%
138	Upper Extremity Deformities, Congenital	6.7%
139	Osteolysis	6.7%
140	Tuberculosis, Spinal	6.5%
141	Jaw Abnormalities	6.3%
142	Mandibulofacial Dysostosis	6.2%
143	Congenital Hypothyroidism	6.2%
144	Prognathism	6%
145	Chronic Fatigue Syndrome	5.8%
146	Antley-Bixler Syndrome Phenotype	5.8%
147	Rheumatoid Arthritis	5.6%
148	Osteoporosis, Postmenopausal	5.6%
149	Juvenile arthritis	5.6%
150	Giant Cell Epulis	5.5%
151	Muscle Weakness	5.5%
152	Dwarfism	5.5%
153	Musculoskeletal Pain	5.4%
154	Familial Periodic Paralysis	5.4%
155	Muscular Dystrophy	5.1%
156	Orbital Myositis	5.1%
157	Dupuytren Contracture	5.1%
158	Pyomyositis	5%
159	Acromegaly	5%
160	Joint Tuberculosis	5%
161	Tuberculosis, Osteoarticular	5%
162	Bone Tuberculosis	5%
163	Rheumatoid Nodule	5%
164	Spondylarthropathies	5%
165	Palatal Neoplasms	5%
166	Micrognathism	4.9%
167	Pierre Robin Syndrome	4.9%
168	Laryngomalacia	4.7%
169	Rubinstein-Taybi Syndrome	4.6%
170	Myotonic Dystrophy	4.6%
171	Eosinophilic Granuloma	4.5%
172	Myalgia	4.5%
173	Retrognathia	4.3%
174	Osteogenesis Imperfecta	4.3%
175	Welander Distal Myopathy	4.1%
176	Mastoiditis	4.1%
177	Petrositis	4.1%
178	Maxillofacial Abnormalities	4.1%
179	Myotonia Congenita	4%
180	Rickets	4%
181	Felty Syndrome	4%
182	Bronchomalacia	4%
183	Tracheomalacia	4%
184	Microcephaly	4%
185	Macrocephaly	4%
186	Hypokalemic periodic paralysis	3.9%
187	Basal Cell Nevus Syndrome	3.6%
188	Cleft Palate	3.4%
189	Dermatomyositis	3.4%
190	Pseudohypoparathyroidism	3.3%
191	Muscular Dystrophy, Duchenne	3.3%
192	Mitochondrial Encephalomyopathies	3.3%
193	Rheumatoid Vasculitis	3.3%
194	Osteomalacia	3.3%
195	Porencephaly	3.3%
196	Noonan Syndrome	2.9%
197	Sicca Syndrome	2.8%
198	Sjogren's Syndrome	2.8%
199	Arthritis, Psoriatic	2.8%
200	Arthritis, Reactive	2.8%
201	Marfan Syndrome	2.6%
202	Holoprosencephaly	2.5%
203	Radicular Cyst	2.4%
204	Cockayne Syndrome	2.4%
205	Nose Neoplasms	2.1%
206	Renal Osteodystrophy	2%
207	Renal rickets	2%
208	MELAS Syndrome	1.6%
209	Kearns-Sayre syndrome	1.5%
210	Familial Hypophosphatemic Rickets	1.1%

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