MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

kyphosis

(UMLS:C2115817)

UMLS ID:: C2115817
MeSH ID:: D007738

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.900.800.500

Synonym(s)

kyphosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Alendronate	FAERS: 79		OFFSIDES US FAERS
2	Teriparatide	FAERS: 25		US FAERS
3	Valproic Acid	FAERS: 25		US FAERS
4	rofecoxib	FAERS: 9		OFFSIDES US FAERS
5	Zoledronic Acid	FAERS: 8 Canada Vigilance: 3		Canada Vigilance OFFSIDES US FAERS
6	Baclofen	FAERS: 4		US FAERS
7	Finasteride	FAERS: 4		US FAERS
8	Methylprednisolone	FAERS: 4		US FAERS
9	Pamidronate	FAERS: 4		US FAERS
10	Prednisolone	FAERS: 4	6725330	CTD US FAERS
11	Pregabalin	FAERS: 4		US FAERS
12	tofacitinib	FAERS: 4		US FAERS
13	Carbamazepine	FAERS: 3		OFFSIDES US FAERS
14	Gabapentin	FAERS: 3		US FAERS
15	Haloperidol	FAERS: 3		US FAERS
16	Megestrol Acetate	FAERS: 3		US FAERS
17	Methotrexate	FAERS: 3		US FAERS
18	Raloxifene Hydrochloride	FAERS: 3		US FAERS
19	Anastrozole	FAERS: 2		OFFSIDES US FAERS
20	Bortezomib	FAERS: 2		US FAERS
21	Erlotinib Hydrochloride	FAERS: 2		US FAERS
22	Esomeprazole	FAERS: 2		US FAERS
23	Fentanyl	FAERS: 2		US FAERS
24	Fluconazole	FAERS: 2		US FAERS
25	Omeprazole	FAERS: 2		US FAERS
26	Paroxetine	FAERS: 2		US FAERS
27	Risedronic Acid	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
28	Rosuvastatin Calcium	FAERS: 2		US FAERS
29	Sitagliptin Phosphate	FAERS: 2		US FAERS
30	Thalidomide	FAERS: 2		OFFSIDES US FAERS
31	Valproic Acid	FAERS: 2		US FAERS
32	aclidinium bromide	FAERS: 2		US FAERS
33	niraparib	FAERS: 2		US FAERS
34	4-hydroxybutyric acid	FAERS: 1		US FAERS
35	CID 129626832	FAERS: 1		US FAERS
36	Clozapine	FAERS: 1		US FAERS
37	Duloxetine Hydrochloride	FAERS: 1		OFFSIDES US FAERS
38	Everolimus	FAERS: 1		US FAERS
39	Exenatide	FAERS: 1		US FAERS
40	Fluoxetine	FAERS: 1		US FAERS
41	Glatiramer Acetate	FAERS: 1		US FAERS
42	Goserelin	FAERS: 1		US FAERS
43	Isotretinoin	FAERS: 1		US FAERS
44	LCZ 696	FAERS: 1		US FAERS
45	Lamotrigine	FAERS: 1		US FAERS
46	Lovastatin	FAERS: 1		US FAERS
47	Methotrexate	FAERS: 1		US FAERS
48	Metoclopramide	FAERS: 1		US FAERS
49	Metoprolol	FAERS: 1		US FAERS
50	Norfloxacin	FAERS: 1		US FAERS
51	NuvaRing	FAERS: 1		US FAERS
52	Octreotide	FAERS: 1		US FAERS
53	Olmesartan Medoxomil	FAERS: 1		US FAERS
54	Pioglitazone	FAERS: 1		US FAERS
55	Pramipexole	FAERS: 1		OFFSIDES US FAERS
56	Pramipexole	FAERS: 1		US FAERS
57	Risperidone	FAERS: 1		US FAERS
58	Rivastigmine	FAERS: 1		US FAERS
59	Sertraline	FAERS: 1		US FAERS
60	Thyroxine	FAERS: 1		US FAERS
61	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
62	Warfarin	FAERS: 1		US FAERS
63	adefovir dipivoxil	FAERS: 1		US FAERS
64	carbidopa, levodopa drug combination	FAERS: 1		US FAERS
65	ponatinib	FAERS: 1		US FAERS
66	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride			OFFSIDES
67	Acetylcysteine			OFFSIDES
68	Ampicillin			OFFSIDES
69	Aripiprazole			SIDER
70	Betamethasone Valerate			OFFSIDES
71	Bethanechol			OFFSIDES
72	Biotin			OFFSIDES
73	Bisacodyl			OFFSIDES
74	Bleomycin			OFFSIDES
75	Bleomycin			OFFSIDES
76	Bupropion			OFFSIDES
77	Calcium Chloride			OFFSIDES
78	Capecitabine			OFFSIDES
79	Cefadroxil			OFFSIDES
80	Ceftriaxone			OFFSIDES
81	Celecoxib			OFFSIDES
82	Chlorhexidine			OFFSIDES
83	Clindamycin			OFFSIDES
84	Cocaine			OFFSIDES
85	Codeine			OFFSIDES
86	Cyproheptadine			OFFSIDES
87	Dacarbazine			OFFSIDES
88	Dapsone			OFFSIDES
89	Deferasirox			OFFSIDES
90	Desonide			OFFSIDES
91	Dicloxacillin			OFFSIDES
92	Dioctyl Sulfosuccinic Acid			OFFSIDES
93	Docetaxel			OFFSIDES
94	Doxorubicin			OFFSIDES
95	Doxycycline			OFFSIDES
96	Dronabinol			OFFSIDES
97	Droperidol			OFFSIDES
98	Dutasteride			OFFSIDES
99	Estradiol			OFFSIDES
100	Estramustine phosphate			OFFSIDES
101	Estramustine			OFFSIDES
102	Ethambutol			OFFSIDES
103	Famotidine			OFFSIDES
104	Fenofibrate			OFFSIDES
105	Fenoterol			OFFSIDES
106	Fludrocortisone			OFFSIDES
107	Flutamide			OFFSIDES
108	Fluticasone-Salmeterol Drug Combination			OFFSIDES
109	Fluvastatin			OFFSIDES
110	Fulvestrant			OFFSIDES
111	Glucovance			OFFSIDES
112	Hydralazine			OFFSIDES
113	Hydrochlorothiazide			OFFSIDES
114	Hydromorphone			OFFSIDES
115	Ibuprofen			OFFSIDES
116	Itraconazole			OFFSIDES
117	Ketamine		27359275	CTD
118	Ketoconazole			OFFSIDES
119	Ketorolac			OFFSIDES
120	Ketorolac Tromethamine			OFFSIDES
121	Lenalidomide			OFFSIDES
122	Letrozole			OFFSIDES
123	Lidoderm			OFFSIDES
124	Linezolid			OFFSIDES
125	Lithium Carbonate			OFFSIDES
126	Magnesium;5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide;trihydrate	Canada Vigilance: 1		Canada Vigilance
127	Melatonin			OFFSIDES
128	Meloxicam			OFFSIDES
129	Melphalan			OFFSIDES
130	Meperidine			OFFSIDES
131	Methadone			OFFSIDES
132	Mometasone Furoate			OFFSIDES
133	Morphine			OFFSIDES
134	Nabumetone			OFFSIDES
135	Naloxone			OFFSIDES
136	Nevirapine			OFFSIDES
137	Nitrendipine			OFFSIDES
138	Nitrofurantoin			OFFSIDES
139	Nortriptyline			OFFSIDES
140	Ofloxacin			OFFSIDES
141	Paclitaxel			OFFSIDES
142	Palonosetron			OFFSIDES
143	Pamidronate			OFFSIDES
144	Penicillin V			OFFSIDES
145	Pentamidine			OFFSIDES
146	Perindopril			OFFSIDES
147	Piperacillin, Tazobactam Drug Combination			OFFSIDES
148	Piroxicam			OFFSIDES
149	Prednisone			OFFSIDES
150	Pyridoxine			OFFSIDES
151	Raloxifene Hydrochloride			OFFSIDES
152	Scopolamine			OFFSIDES
153	Sertraline			OFFSIDES
154	Solifenacin Succinate			OFFSIDES
155	Sulfamethoxazole			OFFSIDES
156	Tamoxifen			OFFSIDES
157	Tenofovir			OFFSIDES
158	Tetracycline			OFFSIDES
159	Ticlopidine			OFFSIDES
160	Tretinoin			OFFSIDES
161	Triamterene			OFFSIDES
162	Ubiquinone			OFFSIDES
163	Valsartan			OFFSIDES
164	Vinblastine			OFFSIDES
165	Vinorelbine			OFFSIDES
166	Vitamin A			OFFSIDES
167	Warfarin		17107801	CTD OFFSIDES
168	Zidovudine			OFFSIDES
169	Ziram		6230523	CTD
170	Zolpidem			OFFSIDES
171	alfacalcidol			OFFSIDES
172	azelastine			OFFSIDES
173	benazepril			OFFSIDES
174	bicalutamide			OFFSIDES
175	chlorhexidine gluconate			OFFSIDES
176	cyclobenzaprine			OFFSIDES
177	efavirenz			OFFSIDES
178	etizolam			OFFSIDES
179	exemestane			OFFSIDES
180	flunisolide			OFFSIDES
181	gemcitabine			OFFSIDES
182	pantethine			OFFSIDES
183	pimecrolimus			OFFSIDES
184	reviparin			OFFSIDES
185	tizanidine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Lordosis	48.4%
2	Spinal Stenosis	34.4%
3	Spondylosis	34.4%
4	Intervertebral Disc Degeneration	34.4%
5	Bone Diseases, Developmental	25.4%
6	Hyperostosis	25.4%
7	Osteitis	25.4%
8	Osteitis Deformans	25.4%
9	Osteochondrosis	25.4%
10	Spinal Neoplasms	24.8%
11	Spondylitis	24.8%
12	Osteoarthropathy, Secondary Hypertrophic	23%
13	Spondylolysis	22.6%
14	Platybasia	21.7%
15	Bone Diseases, Endocrine	18.1%
16	Bone Diseases, Infectious	17.2%
17	Bone neoplasms	17.2%
18	Osteopenia	17.2%
19	Osteochondritis	17.1%
20	Bone Resorption	16.9%
21	Aseptic Necrosis of Bone	16.9%
22	Spondylolisthesis	16.8%
23	Fasciitis	16.4%
24	Foot Deformities	16.4%
25	Arthropathy	16.4%
26	Discitis	16.1%
27	Gigantism	14.9%
28	Ainhum	14.8%
29	Dysostoses	14.8%
30	Spondylarthropathies	13.4%
31	Tuberculosis, Spinal	12.8%
32	Pectus excavatum	11.8%
33	Contracture	11.5%
34	Fasciitis, Plantar	11.5%
35	Jaw Diseases	11.4%
36	Osteoarthritis, Spine	11.3%
37	Cartilage Diseases	10.8%
38	Foot Diseases	10.8%
39	Myopathy	10.8%
40	Rheumatism	10.8%
41	Chondromalacia	10.8%
42	Pectus carinatum	10.7%
43	Ankylosing spondylitis	10.7%
44	Arthrogryposis	10.3%
45	Multiple Epiphyseal Dysplasia	10.1%
46	Osteochondrodysplasias	10.1%
47	Osteomyelitis	9.9%
48	Osteoporosis	9.9%
49	Periostitis	9.9%
50	Bone Demineralization, Pathologic	9.9%
51	Post-Traumatic Osteoporosis	9.9%
52	Alveolar Bone Loss	9.8%
53	Femur Head Necrosis	9.8%
54	Osteolysis	9.8%
55	Chondrodysplasia Punctata	9.7%
56	Enchondromatosis	9.7%
57	Osteosclerosis	9.7%
58	Kashin-Beck Disease	9.7%
59	Klippel-Feil Syndrome	9.2%
60	Synostosis	9.2%
61	Fibromyalgia	8.5%
62	Polymyalgia Rheumatica	8.5%
63	Arthritis, Psoriatic	8.5%
64	Arthritis	8.5%
65	Bursitis	8.5%
66	Joint Instability	8.5%
67	Metatarsalgia	8.5%
68	Myofascial Pain Syndromes	8.5%
69	Rhabdomyolysis	8.5%
70	Synovitis	8.5%
71	Joint laxity	8.5%
72	Polyarthritis	8.5%
73	Frozen shoulder	8.5%
74	Patellofemoral Pain Syndrome	8.5%
75	Congenital Hypothyroidism	8.3%
76	Eosinophilic Granuloma	8.2%
77	Dwarfism	8%
78	Arthritis, Reactive	7.9%
79	Acromegaly	7.3%
80	Joint Tuberculosis	7.3%
81	Tuberculosis, Osteoarticular	7.3%
82	Bone Tuberculosis	7.3%
83	Craniofacial Dysostosis	7.3%
84	Melorheostosis	7.2%
85	Osteopetrosis	7.2%
86	Rheumatic Fever	6.7%
87	Hip Contracture	6.6%
88	Periarthritis	6.6%
89	Osteoporosis, Postmenopausal	6.5%
90	Gout	6.1%
91	Ischemic contracture	6%
92	Rickets	5.9%
93	Compartment syndromes	5.7%
94	Maxillary Diseases	5.7%
95	Tendinitis	5.7%
96	Tendinopathy	5.7%
97	Temporomandibular Joint Disorders	5.7%
98	Craniosynostosis	5.7%
99	Syndactyly	5.7%
100	Brachycephaly	5.7%
101	Hemarthrosis	5.6%
102	Myositis	5.6%
103	Tietze's Syndrome	5.6%
104	Limb Deformities, Congenital	5.6%
105	Isaacs syndrome	5.6%
106	Craniofacial Abnormalities	5.6%
107	Myotonic Disorders	5.6%
108	Rheumatoid Arthritis	5.4%
109	Juvenile arthritis	5.4%
110	Osteoarthritis, Knee	5.4%
111	Osteogenesis Imperfecta	5%
112	Bunion	4.9%
113	Fibrodysplasia Ossificans Progressiva	4.9%
114	Myoglobinuria	4.9%
115	Myositis Ossificans	4.9%
116	Pseudohypoparathyroidism	4.9%
117	Tenosynovitis	4.9%
118	Sacroiliitis	4.9%
119	Talipes	4.9%
120	Mastoiditis	4.8%
121	Petrositis	4.8%
122	Acrocephalosyndactylia	4.5%
123	Temporomandibular Joint Dysfunction Syndrome	4.5%
124	Medial Tibial Stress Syndrome	4.3%
125	Mitochondrial Myopathies	4.2%
126	Mandibulofacial Dysostosis	4.2%
127	Muscle Cramp	4.2%
128	Eosinophilia-Myalgia Syndrome	4.2%
129	Goldenhar Syndrome	4.2%
130	Gastroschisis	4.2%
131	Poland Syndrome	4.1%
132	Muscle Rigidity	4.1%
133	Muscle Spasticity	4.1%
134	Cogwheel Rigidity	4.1%
135	Nuchal Rigidity	4.1%
136	Rheumatoid Nodule	4.1%
137	Antley-Bixler Syndrome Phenotype	4%
138	Osteomalacia	3.8%
139	Marfan Syndrome	3.8%
140	Arthritis, Gouty	3.8%
141	Rubinstein-Taybi Syndrome	3.7%
142	Basal Cell Nevus Syndrome	3.6%
143	Chronic Fatigue Syndrome	3.5%
144	Palatal Neoplasms	3.5%
145	Nail-Patella Syndrome	3.4%
146	Giant Cell Epulis	3.4%
147	Muscle Weakness	3.4%
148	Arthritis, Infectious	3.4%
149	Congenital clubfoot	3.4%
150	Vertical Talus	3.4%
151	Musculoskeletal Pain	3.3%
152	Jaw Abnormalities	3.3%
153	Familial Periodic Paralysis	3.3%
154	Anterior Compartment Syndrome	3.3%
155	Enthesopathy	3.3%
156	Arthritis, Experimental	3.3%
157	Abdominal Compartment Syndrome	3.3%
158	Arthralgia	3.3%
159	Polyarthralgia	3.3%
160	Felty Syndrome	3.3%
161	Amelia	3.3%
162	Arachnodactyly	3.3%
163	Ectromelia	3.3%
164	Hemimelia	3.3%
165	Phocomelia	3.3%
166	Sirenomelia	3.3%
167	Polymyositis	3.3%
168	Polydactyly	3.3%
169	Brachydactyly	3.3%
170	Plagiocephaly	3.3%
171	Lower Extremity Deformities, Congenital	3.3%
172	Upper Extremity Deformities, Congenital	3.3%
173	Laryngomalacia	2.9%
174	Cockayne Syndrome	2.8%
175	Myalgia	2.7%
176	Rheumatoid Vasculitis	2.7%
177	Prognathism	2.7%
178	Hip Dislocation	2.6%
179	Shoulder Dislocation	2.6%
180	Hip Dysplasia	2.6%
181	Nose Neoplasms	2.5%
182	Muscular Dystrophy	2.5%
183	Orbital Myositis	2.5%
184	Dupuytren Contracture	2.5%
185	Pyomyositis	2.5%
186	Renal Osteodystrophy	2.4%
187	Renal rickets	2.4%
188	Sicca Syndrome	2.3%
189	Sjogren's Syndrome	2.3%
190	Micrognathism	2.1%
191	Pierre Robin Syndrome	2.1%
192	Myotonic Dystrophy	2%
193	Maxillofacial Abnormalities	2%
194	Myotonia Congenita	2%
195	Bronchomalacia	2%
196	Tracheomalacia	2%
197	Microcephaly	1.9%
198	Macrocephaly	1.9%
199	Hypokalemic periodic paralysis	1.9%
200	Shoulder Pain	1.9%
201	Retrognathia	1.8%
202	Mitochondrial Encephalomyopathies	1.6%
203	Welander Distal Myopathy	1.6%
204	Cleft Palate	1.5%
205	Noonan Syndrome	1.4%
206	Dermatomyositis	1.3%
207	Muscular Dystrophy, Duchenne	1.3%
208	Porencephaly	1.3%
209	Holoprosencephaly	1.2%
210	Familial Hypophosphatemic Rickets	1.1%
211	Radicular Cyst	0.8%
212	MELAS Syndrome	0.6%
213	Kearns-Sayre syndrome	0.6%

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