MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Joint laxity

(UMLS:C0086437)

UMLS ID:: C0086437
MeSH ID:: D007593

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.521

Synonym(s)

Joint laxity

Hyperlaxity

Joint ligamentous laxity

Joints--Hypermobility

Lax joints

Ligamentous laxity

Loose-jointedness

Loosejointedness

hypermobility joint

10.

hypermobility joints

11.

joint hypermobility

12.

joint laxity

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Valproic Acid	FAERS: 25	US FAERS
2	Valproic Acid	FAERS: 4	US FAERS
3	4-Aminopyridine	FAERS: 1	US FAERS
4	4-hydroxybutyric acid	FAERS: 1	US FAERS
5	Alendronate	FAERS: 1	US FAERS
6	Esomeprazole	FAERS: 1	US FAERS
7	MDV 3100	FAERS: 1	US FAERS
8	NuvaRing	FAERS: 1	US FAERS
9	Tacrolimus	FAERS: 1	US FAERS
10	Valproic Acid	FAERS: 1	US FAERS
11	pirfenidone	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Arthritis	42.9%
2	Bursitis	42.9%
3	Synovitis	42.9%
4	Polyarthritis	42.9%
5	Frozen shoulder	42.9%
6	Patellofemoral Pain Syndrome	42.9%
7	Periarthritis	40.9%
8	Contracture	38.1%
9	Osteoarthropathy, Secondary Hypertrophic	38.1%
10	Sacroiliitis	31%
11	Ankylosing spondylitis	29.5%
12	Arthrogryposis	28.2%
13	Hemarthrosis	27.9%
14	Metatarsalgia	27.8%
15	Hip Contracture	27.3%
16	Osteoarthritis, Spine	26.7%
17	Gout	24.7%
18	Osteoarthritis, Knee	23.6%
19	Arthritis, Psoriatic	23.5%
20	Bone Diseases	23.1%
21	Fasciitis	23.1%
22	Foot Deformities	23.1%
23	Rheumatic Fever	22.2%
24	Spondylarthropathies	21.5%
25	Arthritis, Reactive	21.5%
26	Arthritis, Infectious	20.9%
27	Arthritis, Experimental	20.5%
28	Temporomandibular Joint Disorders	20.3%
29	Ischemic contracture	20.3%
30	Arthritis, Gouty	19.7%
31	Fasciitis, Plantar	19%
32	Rheumatoid Arthritis	18.1%
33	Juvenile arthritis	18.1%
34	Rheumatoid Nodule	17.5%
35	Nail-Patella Syndrome	16.7%
36	Arthralgia	16.1%
37	Polyarthralgia	16.1%
38	Temporomandibular Joint Dysfunction Syndrome	16%
39	Hip Dislocation	15.8%
40	Jaw Diseases	15.8%
41	Shoulder Dislocation	15.8%
42	Hip Dysplasia	15.8%
43	Cartilage Diseases	15%
44	Foot Diseases	15%
45	Myopathy	15%
46	Rheumatism	15%
47	Chondromalacia	15%
48	Bone Diseases, Developmental	14.3%
49	Hyperostosis	14.3%
50	Myofascial Pain Syndromes	14.3%
51	Osteitis	14.3%
52	Osteitis Deformans	14.3%
53	Osteochondrosis	14.3%
54	Rhabdomyolysis	14.3%
55	Spinal Diseases	14.3%
56	Fibromyalgia	14%
57	Osteochondritis	14%
58	Polymyalgia Rheumatica	14%
59	Felty Syndrome	14%
60	Pectus carinatum	12.6%
61	Platybasia	12.1%
62	Pectus excavatum	12.1%
63	Shoulder Pain	11.8%
64	Rheumatoid Vasculitis	11.6%
65	Klippel-Feil Syndrome	11.1%
66	Synostosis	11.1%
67	Talipes	10.9%
68	Ainhum	10.3%
69	Bunion	10.3%
70	Dysostoses	10.3%
71	Fibrodysplasia Ossificans Progressiva	10.3%
72	Myoglobinuria	10.3%
73	Myositis Ossificans	10.3%
74	Spinal Stenosis	10.3%
75	Spondylosis	10.3%
76	Tenosynovitis	10.3%
77	Intervertebral Disc Degeneration	10.3%
78	Gigantism	10.2%
79	Spinal Neoplasms	10.2%
80	Spondylitis	10.2%
81	Bone Diseases, Endocrine	10%
82	Sicca Syndrome	10%
83	Sjogren's Syndrome	10%
84	Bone Diseases, Infectious	9.5%
85	Bone neoplasms	9.5%
86	Compartment syndromes	9.5%
87	Maxillary Diseases	9.5%
88	Osteopenia	9.5%
89	Tendinitis	9.5%
90	Tendinopathy	9.5%
91	Bone Resorption	9.3%
92	Myositis	9.3%
93	Tietze's Syndrome	9.3%
94	Limb Deformities, Congenital	9.3%
95	Isaacs syndrome	9.3%
96	Craniofacial Abnormalities	9.3%
97	Aseptic Necrosis of Bone	9.3%
98	Myotonic Disorders	9.3%
99	Congenital clubfoot	9.3%
100	Vertical Talus	9.3%
101	Craniofacial Dysostosis	9.2%
102	Craniosynostosis	9.1%
103	Syndactyly	9.1%
104	Brachycephaly	9.1%
105	Chondrodysplasia Punctata	8.5%
106	Enchondromatosis	8.5%
107	Lordosis	8.5%
108	Osteosclerosis	8.5%
109	Spondylolysis	8.5%
110	kyphosis	8.5%
111	Kashin-Beck Disease	8.5%
112	Acrocephalosyndactylia	8.3%
113	Discitis	8.3%
114	Poland Syndrome	7.7%
115	Melorheostosis	7.6%
116	Osteopetrosis	7.6%
117	Spondylolisthesis	7.6%
118	Goldenhar Syndrome	7.1%
119	Medial Tibial Stress Syndrome	7%
120	Multiple Epiphyseal Dysplasia	7%
121	Osteochondrodysplasias	7%
122	Mitochondrial Myopathies	6.9%
123	Muscle Cramp	6.8%
124	Eosinophilia-Myalgia Syndrome	6.8%
125	Gastroschisis	6.8%
126	Anterior Compartment Syndrome	6.8%
127	Osteomyelitis	6.8%
128	Osteoporosis	6.8%
129	Periostitis	6.8%
130	Enthesopathy	6.8%
131	Bone Demineralization, Pathologic	6.8%
132	Post-Traumatic Osteoporosis	6.8%
133	Abdominal Compartment Syndrome	6.8%
134	Muscle Rigidity	6.8%
135	Muscle Spasticity	6.8%
136	Cogwheel Rigidity	6.8%
137	Nuchal Rigidity	6.8%
138	Alveolar Bone Loss	6.7%
139	Amelia	6.7%
140	Arachnodactyly	6.7%
141	Ectromelia	6.7%
142	Femur Head Necrosis	6.7%
143	Hemimelia	6.7%
144	Phocomelia	6.7%
145	Sirenomelia	6.7%
146	Polymyositis	6.7%
147	Polydactyly	6.7%
148	Brachydactyly	6.7%
149	Plagiocephaly	6.7%
150	Lower Extremity Deformities, Congenital	6.7%
151	Upper Extremity Deformities, Congenital	6.7%
152	Osteolysis	6.7%
153	Tuberculosis, Spinal	6.5%
154	Jaw Abnormalities	6.3%
155	Mandibulofacial Dysostosis	6.2%
156	Congenital Hypothyroidism	6.2%
157	Prognathism	6%
158	Chronic Fatigue Syndrome	5.8%
159	Antley-Bixler Syndrome Phenotype	5.8%
160	Osteoporosis, Postmenopausal	5.6%
161	Giant Cell Epulis	5.5%
162	Muscle Weakness	5.5%
163	Dwarfism	5.5%
164	Musculoskeletal Pain	5.4%
165	Familial Periodic Paralysis	5.4%
166	Muscular Dystrophy	5.1%
167	Orbital Myositis	5.1%
168	Dupuytren Contracture	5.1%
169	Pyomyositis	5%
170	Acromegaly	5%
171	Joint Tuberculosis	5%
172	Tuberculosis, Osteoarticular	5%
173	Bone Tuberculosis	5%
174	Palatal Neoplasms	5%
175	Micrognathism	4.9%
176	Pierre Robin Syndrome	4.9%
177	Laryngomalacia	4.7%
178	Rubinstein-Taybi Syndrome	4.6%
179	Myotonic Dystrophy	4.6%
180	Eosinophilic Granuloma	4.5%
181	Myalgia	4.5%
182	Retrognathia	4.3%
183	Osteogenesis Imperfecta	4.3%
184	Welander Distal Myopathy	4.1%
185	Mastoiditis	4.1%
186	Petrositis	4.1%
187	Maxillofacial Abnormalities	4.1%
188	Myotonia Congenita	4%
189	Rickets	4%
190	Bronchomalacia	4%
191	Tracheomalacia	4%
192	Microcephaly	4%
193	Macrocephaly	4%
194	Hypokalemic periodic paralysis	3.9%
195	Basal Cell Nevus Syndrome	3.6%
196	Cleft Palate	3.4%
197	Dermatomyositis	3.4%
198	Pseudohypoparathyroidism	3.3%
199	Muscular Dystrophy, Duchenne	3.3%
200	Mitochondrial Encephalomyopathies	3.3%
201	Osteomalacia	3.3%
202	Porencephaly	3.3%
203	Noonan Syndrome	2.9%
204	Marfan Syndrome	2.6%
205	Holoprosencephaly	2.5%
206	Radicular Cyst	2.4%
207	Cockayne Syndrome	2.4%
208	Nose Neoplasms	2.1%
209	Renal Osteodystrophy	2%
210	Renal rickets	2%
211	MELAS Syndrome	1.6%
212	Kearns-Sayre syndrome	1.5%
213	Familial Hypophosphatemic Rickets	1.1%

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