MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Alveolar Bone Loss

(UMLS:C0002382)

Definition:: Resorption or wasting of the tooth-supporting bone (ALVEOLAR PROCESS) in the MAXILLA or MANDIBLE.
UMLS ID:: C0002382
MeSH ID:: D016301

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.264.150

Classification 2:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.714.354.500

Synonym(s)

Alveolar Bone Loss

Alveolar bone loss

alveolar bone loss

atrophy; alveolar process

periodontal bone loss

periodontal resorption

process; alveolar, atrophy

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Dimethyl Sulfoxide	26497626	CTD
2	Etoricoxib	17225004	CTD
3	Indomethacin	17225004	CTD
4	Resveratrol	26497626	CTD
5	mangiferin	19026997	CTD
6	tanshinone	31108107	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Gingival Recession	35.8%
2	Gingival Atrophy	35.8%
3	Ainhum	30.8%
4	Gingival Diseases	23.1%
5	Periodontitis	23.1%
6	Peri-Implantitis	23.1%
7	Osteolysis	23%
8	Tooth Loss	21.8%
9	Osteoarthropathy, Secondary Hypertrophic	20.5%
10	Bone Diseases, Developmental	20.2%
11	Hyperostosis	20.2%
12	Osteitis	20.2%
13	Osteitis Deformans	20.2%
14	Osteochondrosis	20.2%
15	Spinal Diseases	20.2%
16	Jaw Diseases	17.4%
17	Burning Mouth Syndrome	16.9%
18	Lip Diseases	16.9%
19	Microglossia	16.9%
20	Oral Submucous Fibrosis	16.9%
21	Salivary Gland Diseases	16.9%
22	Stomatitis	16.9%
23	Tongue Diseases	16.9%
24	Oral Ulcer	16.9%
25	Osteochondritis	16.3%
26	Facial Hemiatrophy	16.1%
27	Melkersson-Rosenthal Syndrome	16.1%
28	Bone Diseases, Endocrine	15.9%
29	Gigantism	15.9%
30	Spinal Neoplasms	15.9%
31	Spondylitis	15.9%
32	Bone Diseases, Infectious	15.4%
33	Bone neoplasms	15.4%
34	Osteopenia	15.4%
35	Platybasia	15.4%
36	Gingivitis	15.2%
37	Pericoronitis	15.2%
38	Aggressive Periodontitis	15.2%
39	Gingival Overgrowth	15.2%
40	Aseptic Necrosis of Bone	15.1%
41	Gingival Hemorrhage	15%
42	Giant Cell Epulis	14%
43	Mouth Abnormalities	13.6%
44	Bell Palsy	13.4%
45	Dysostoses	13.2%
46	Spinal Stenosis	13.2%
47	Spondylosis	13.2%
48	Intervertebral Disc Degeneration	13.2%
49	Facial Nerve Diseases	12.8%
50	Granulomatosis, Orofacial	12.8%
51	Oral candidiasis	12.6%
52	Mouth Neoplasms	12.6%
53	Oral Fistula	12.6%
54	Lichen Planus, Oral	12.4%
55	Pectus excavatum	12.1%
56	Salivary Gland Fistula	11.8%
57	Salivary Gland Neoplasms	11.8%
58	Tongue Neoplasms	11.8%
59	Fasciitis	11.8%
60	Foot Deformities	11.8%
61	Arthropathy	11.8%
62	Temporomandibular Joint Disorders	11.7%
63	Discitis	11.7%
64	Pectus carinatum	11.6%
65	Gingival Hyperplasia	11.4%
66	Gingival Hypertrophy	11.4%
67	Tooth Diseases	10.6%
68	Arthrogryposis	10.3%
69	Contracture	10.3%
70	Fasciitis, Plantar	10.3%
71	Multiple Epiphyseal Dysplasia	10.1%
72	Osteochondrodysplasias	10.1%
73	Congenital Hypothyroidism	10%
74	Facial paralysis	10%
75	Klippel-Feil Syndrome	10%
76	Synostosis	10%
77	Facial Paresis	10%
78	Osteomyelitis	9.9%
79	Osteoporosis	9.9%
80	Periostitis	9.9%
81	Bone Demineralization, Pathologic	9.9%
82	Post-Traumatic Osteoporosis	9.9%
83	Hemifacial Spasm	9.9%
84	Cheilitis	9.9%
85	Drooling	9.9%
86	Glossitis	9.9%
87	Macroglossia	9.9%
88	Sialadenitis	9.9%
89	Sialometaplasia, Necrotizing	9.9%
90	Sialorrhea	9.9%
91	Aphthous Stomatitis	9.9%
92	Xerostomia	9.9%
93	Glossoptosis	9.9%
94	Femur Head Necrosis	9.8%
95	Chondrodysplasia Punctata	9.8%
96	Enchondromatosis	9.8%
97	Lordosis	9.8%
98	Osteosclerosis	9.8%
99	Spondylolysis	9.8%
100	kyphosis	9.8%
101	Kashin-Beck Disease	9.8%
102	Parotitis	9.8%
103	Parotid Neoplasms	9.7%
104	Radicular Cyst	9.7%
105	Tuberculosis, Spinal	9.7%
106	Palatal Neoplasms	9.6%
107	Osteoarthritis, Spine	9.5%
108	Maxillary Diseases	9.4%
109	Cartilage Diseases	8.8%
110	Foot Diseases	8.8%
111	Myopathy	8.8%
112	Rheumatism	8.8%
113	Chondromalacia	8.8%
114	Ankylosing spondylitis	8.6%
115	Spondylarthropathies	8.5%
116	Craniofacial Dysostosis	8.5%
117	Eosinophilic Granuloma	8.5%
118	Dwarfism	8.4%
119	Pharyngeal Diseases	8.3%
120	Temporomandibular Joint Dysfunction Syndrome	8.2%
121	Fibromyalgia	8.2%
122	Polymyalgia Rheumatica	8.2%
123	Melorheostosis	8.1%
124	Metatarsalgia	8.1%
125	Osteopetrosis	8.1%
126	Spondylolisthesis	8.1%
127	Macrostomia	7.9%
128	Microstomia	7.9%
129	Acromegaly	7.9%
130	Joint Tuberculosis	7.9%
131	Tuberculosis, Osteoarticular	7.9%
132	Bone Tuberculosis	7.9%
133	Facial Neuralgia	7.4%
134	Dental Fistula	7.4%
135	Oroantral Fistula	7.4%
136	Osteoporosis, Postmenopausal	7.3%
137	Craniosynostosis	7.2%
138	Syndactyly	7.2%
139	Brachycephaly	7.2%
140	Arthritis, Psoriatic	7.2%
141	Jaw Abnormalities	7.1%
142	Cleft Palate	7%
143	Ulcerative stomatitis	6.9%
144	Acrocephalosyndactylia	6.8%
145	Arthritis	6.7%
146	Bursitis	6.7%
147	Joint Instability	6.7%
148	Myofascial Pain Syndromes	6.7%
149	Rhabdomyolysis	6.7%
150	Synovitis	6.7%
151	Joint laxity	6.7%
152	Polyarthritis	6.7%
153	Frozen shoulder	6.7%
154	Patellofemoral Pain Syndrome	6.7%
155	Rheumatic Fever	6.7%
156	Gout	6.6%
157	Ischemic contracture	6.6%
158	Arthritis, Reactive	6.6%
159	Hip Contracture	6.6%
160	Periarthritis	6.6%
161	Rickets	6.6%
162	Glossitis, Benign Migratory	6.5%
163	Behcet Syndrome	6.2%
164	Vesicular Stomatitis	6.2%
165	Prognathism	6%
166	Osteogenesis Imperfecta	6%
167	Goldenhar Syndrome	5.9%
168	Poland Syndrome	5.9%
169	Mastoiditis	5.8%
170	Petrositis	5.8%
171	Osteoarthritis, Knee	5.7%
172	Talipes	5.7%
173	Mandibulofacial Dysostosis	5.7%
174	Rheumatoid Arthritis	5.6%
175	Juvenile arthritis	5.6%
176	Pseudohypoparathyroidism	5.6%
177	Bruxism	5.6%
178	Dental Leakage	5.6%
179	Hypercementosis	5.6%
180	Malocclusion	5.6%
181	Tooth Crowding	5.6%
182	Tooth Discoloration	5.6%
183	Tooth Demineralization	5.6%
184	Tooth Ankylosis	5.6%
185	Antley-Bixler Syndrome Phenotype	5.3%
186	Sicca Syndrome	5.3%
187	Sjogren's Syndrome	5.3%
188	Retrognathia	5.2%
189	Compartment syndromes	5.1%
190	Tendinitis	5.1%
191	Tendinopathy	5.1%
192	Basal Cell Nevus Syndrome	5.1%
193	Hemarthrosis	5%
194	Myositis	5%
195	Tietze's Syndrome	5%
196	Limb Deformities, Congenital	5%
197	Isaacs syndrome	5%
198	Craniofacial Abnormalities	5%
199	Myotonic Disorders	5%
200	Mobius Syndrome	5%
201	Maxillofacial Abnormalities	5%
202	Herpes Zoster Oticus	5%
203	Leukoplakia, Oral	4.9%
204	Herpes Labialis	4.9%
205	Trigeminal Nerve Disorder	4.9%
206	Osteomalacia	4.8%
207	Rubinstein-Taybi Syndrome	4.7%
208	Micrognathism	4.7%
209	Pierre Robin Syndrome	4.7%
210	Arthritis, Gouty	4.6%
211	Rheumatoid Nodule	4.6%
212	Marfan Syndrome	4.5%
213	Tooth Injuries	4.4%
214	Congenital clubfoot	4.4%
215	Vertical Talus	4.4%
216	Bunion	4.4%
217	Fibrodysplasia Ossificans Progressiva	4.4%
218	Myoglobinuria	4.4%
219	Myositis Ossificans	4.4%
220	Tenosynovitis	4.4%
221	Sacroiliitis	4.4%
222	Tooth Resorption	4.3%
223	Facial Nerve Injuries	4.2%
224	Toothache	4.1%
225	Medial Tibial Stress Syndrome	4.1%
226	Mitochondrial Myopathies	4%
227	Muscle Cramp	4%
228	Eosinophilia-Myalgia Syndrome	4%
229	Gastroschisis	4%
230	Muscle Rigidity	4%
231	Muscle Spasticity	4%
232	Cogwheel Rigidity	4%
233	Nuchal Rigidity	4%
234	Dental Enamel Hypoplasia	3.9%
235	Hypodontia	3.9%
236	Felty Syndrome	3.8%
237	Cockayne Syndrome	3.7%
238	Toxic Epidermal Necrolysis	3.7%
239	Stevens-Johnson Syndrome	3.7%
240	Mumps	3.6%
241	Trigeminal Neuralgia	3.6%
242	Chronic Fatigue Syndrome	3.5%
243	Pharyngitis	3.4%
244	Nail-Patella Syndrome	3.4%
245	Nose Neoplasms	3.4%
246	Muscle Weakness	3.4%
247	Arthritis, Infectious	3.4%
248	Musculoskeletal Pain	3.3%
249	Familial Periodic Paralysis	3.3%
250	Anterior Compartment Syndrome	3.3%
251	Enthesopathy	3.3%
252	Arthritis, Experimental	3.3%
253	Abdominal Compartment Syndrome	3.3%
254	Arthralgia	3.3%
255	Dental caries	3.3%
256	Dental Plaque	3.3%
257	Dental Pulp Calcification	3.3%
258	Pulpitis	3.3%
259	Tooth Erosion	3.3%
260	Polyarthralgia	3.3%
261	Amelia	3.3%
262	Arachnodactyly	3.3%
263	Ectromelia	3.3%
264	Hemimelia	3.3%
265	Phocomelia	3.3%
266	Sirenomelia	3.3%
267	Polymyositis	3.3%
268	Polydactyly	3.3%
269	Brachydactyly	3.3%
270	Plagiocephaly	3.3%
271	Lower Extremity Deformities, Congenital	3.3%
272	Upper Extremity Deformities, Congenital	3.3%
273	Rheumatoid Vasculitis	3.3%
274	Renal Osteodystrophy	3.2%
275	Renal rickets	3.2%
276	Laryngomalacia	2.9%
277	Nasopharyngitis	2.8%
278	Pharyngeal Neoplasms	2.8%
279	Myalgia	2.8%
280	Hip Dislocation	2.7%
281	Shoulder Dislocation	2.7%
282	Hip Dysplasia	2.7%
283	Muscular Dystrophy	2.7%
284	Orbital Myositis	2.7%
285	Dupuytren Contracture	2.7%
286	Pyomyositis	2.6%
287	Myotonic Dystrophy	2.6%
288	Tooth Avulsion	2.5%
289	Dental Pulp Necrosis	2.5%
290	Nasopharyngeal Neoplasms	2.5%
291	Myotonia Congenita	2.2%
292	Bronchomalacia	2.2%
293	Tracheomalacia	2.2%
294	Microcephaly	2.2%
295	Macrocephaly	2.2%
296	Hypokalemic periodic paralysis	2.2%
297	Shoulder Pain	2.2%
298	Lemierre Syndrome	2.1%
299	Tonsillitis	2%
300	Sleep Bruxism	2%
301	Welander Distal Myopathy	2%
302	Mitochondrial Encephalomyopathies	1.9%
303	Familial Hypophosphatemic Rickets	1.7%
304	Dermatomyositis	1.7%
305	Noonan Syndrome	1.7%
306	Retropharyngeal Abscess	1.6%
307	Hypopharyngeal Neoplasms	1.6%
308	Hypopharyngeal Cancer	1.6%
309	Muscular Dystrophy, Duchenne	1.6%
310	Porencephaly	1.6%
311	Holoprosencephaly	1.5%
312	Nasopharyngeal carcinoma	1.4%
313	Peritonsillar Abscess	1.1%
314	Tonsillar Neoplasms	1.1%
315	MELAS Syndrome	0.9%
316	Kearns-Sayre syndrome	0.8%

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