MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vocal Cord Dysfunction

(UMLS:C0859897)

Definition:: A disorder characterized by an intermittent abnormal VOCAL CORDS movement toward the midline during inspiration or expiration resulting in upper AIRWAY OBSTRUCTION.
UMLS ID:: C0859897
MeSH ID:: D064706

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.360.895|C08.618.980

Classification 2:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.400.895

Synonym(s)

Vocal Cord Dysfunction

Vocal cord dysfunction

cord dysfunction vocal

vocal cord dysfunction

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Tramadol	FAERS: 4	US FAERS
2	Rocuronium	FAERS: 2	US FAERS
3	ponatinib	FAERS: 2	US FAERS
4	Beclomethasone	FAERS: 1	US FAERS
5	Ibandronic Acid	FAERS: 1	US FAERS
6	Imatinib Mesylate	FAERS: 1	US FAERS
7	Lamotrigine	FAERS: 1	US FAERS
8	Lurasidone Hydrochloride	FAERS: 1	US FAERS
9	MDV 3100	FAERS: 1	US FAERS
10	Methylprednisolone	FAERS: 1	US FAERS
11	Mirtazapine	FAERS: 1	US FAERS
12	Nexium 24hr	FAERS: 1	US FAERS
13	Prednisone	FAERS: 1	US FAERS
14	Ranolazine	FAERS: 1	US FAERS
15	Tramadol	FAERS: 1	US FAERS
16	apixaban	FAERS: 1	US FAERS
17	metaxalone	FAERS: 1	US FAERS
18	mirabegron	FAERS: 1	US FAERS
19	pirfenidone	FAERS: 1	US FAERS
20	Ibuprofen	Canada Vigilance: 1	Canada Vigilance
21	Omeprazole	Canada Vigilance: 1	Canada Vigilance

Similar ADE(s)

	Name	Semantic Similarity
1	Laryngitis	42.9%
2	Granuloma, Laryngeal	41.9%
3	Laryngeal Edema	40%
4	Laryngocele	36.4%
5	Laryngeal neoplasm	35.2%
6	Respiratory Distress Syndrome, Adult	34.3%
7	Laryngostenosis	32.9%
8	Croup	29.2%
9	Altitude Sickness	28.6%
10	Respiratory Insufficiency	28.6%
11	Respiratory Depression	28.6%
12	Respiratory Failure	28.6%
13	Voice Disorders	28.3%
14	Voice Disturbance	28.3%
15	Respiratory Distress Syndrome, Newborn	28.2%
16	Hoarseness	28.1%
17	Nose Diseases	27.3%
18	Bronchitis	25.9%
19	Laryngomalacia	24.6%
20	Tracheobronchomegaly	24.2%
21	Vocal Cord Paralysis	24.2%
22	Rhinitis	23.8%
23	Pleuropneumonia	23.5%
24	Bronchopneumonia	23.3%
25	Pleurisy	22.9%
26	Pneumonia	22.9%
27	Lobar Pneumonia	22.9%
28	Tracheitis	22.9%
29	Respiratory Aspiration	22.9%
30	Pneumonitis	22.9%
31	Apnea	22.5%
32	Cheyne-Stokes Respiration	22.5%
33	Dyspnea	22.5%
34	Hyperventilation	22.5%
35	Mouth Breathing	22.5%
36	Tachypnea	22.5%
37	Laryngopharyngeal Reflux	22.3%
38	Bronchial Diseases	22.2%
39	Lung diseases	22.2%
40	Pleural Diseases	22.2%
41	Thoracic Diseases	22.2%
42	Tracheal Diseases	22.2%
43	Asthma	21.9%
44	Bronchitis, Chronic	21.4%
45	Airway Obstruction	21.1%
46	Choking	21.1%
47	Hyaline Membrane Disease	20.6%
48	Aphonia	20.5%
49	Dysphonia	20.5%
50	Choanal Atresia	20.2%
51	Sinusitis	19.8%
52	Bronchiolitis	19.4%
53	Meconium Aspiration Syndrome	19.3%
54	Lung Diseases, Fungal	19%
55	Bronchial Fistula	18.7%
56	Lung Abscess	18.7%
57	Lung Neoplasms	18.7%
58	Pleural Neoplasms	18.7%
59	Primary Ciliary Dyskinesia	18.7%
60	Tuberculosis, Pulmonary	18.6%
61	Paranasal Sinus Neoplasms	18.3%
62	Acute Chest Syndrome	18.1%
63	Respiratory Tract Infections	17.6%
64	Pleural Effusion, Malignant	17.5%
65	Granuloma, Respiratory Tract	17.4%
66	Respiratory Hypersensitivity	17.4%
67	Respiratory Tract Fistula	17.4%
68	Granuloma, Lethal Midline	17.1%
69	Nose Deformities, Acquired	17.1%
70	Aspiration Pneumonia	16.7%
71	Hypoventilation	16.7%
72	Nose Neoplasms	16.6%
73	Acidosis, Respiratory	16.6%
74	Alkalosis, Respiratory	16.6%
75	Sleep Apnea Syndromes	16.6%
76	Aspergillosis, Allergic Bronchopulmonary	16.2%
77	Bronchial Neoplasms	16.1%
78	Tracheal Neoplasms	15.9%
79	Idiopathic Pulmonary Fibrosis	15.2%
80	Maxillary Sinus Neoplasms	14.9%
81	Atelectasis	14.3%
82	Bronchospasm	14.3%
83	Bronchiectasis	14.3%
84	Chylothorax	14.3%
85	Hydropneumothorax	14.3%
86	Hydrothorax	14.3%
87	Pulmonary Hypertension	14.3%
88	Pharyngitis	14.3%
89	Pneumoconiosis	14.3%
90	Pneumonia, Viral	14.3%
91	Pneumothorax	14.3%
92	Pulmonary Alveolar Proteinosis	14.3%
93	Pulmonary Edema	14.3%
94	Pulmonary Fibrosis	14.3%
95	Tracheal Stenosis	14.3%
96	Bronchial Hyperreactivity	14.3%
97	Hamman-Rich syndrome	14.3%
98	Lung Diseases, Interstitial	14.3%
99	Lung Diseases, Obstructive	14.3%
100	Nasal Polyps	14.1%
101	Pneumonia, Bacterial	14%
102	Rhinoscleroma	13.7%
103	Dyspnea, Paroxysmal	13.7%
104	Respiratory Paralysis	13.7%
105	Pneumonia, Lipid	13.7%
106	Asthma, Exercise-Induced	13.7%
107	Status Asthmaticus	13.7%
108	Multiple Pulmonary Nodules	13.7%
109	Sleep Apnea, Obstructive	13.7%
110	Sleep Apnea, Central	13.7%
111	Hay fever	13%
112	Rhinitis, Allergic, Perennial	13%
113	Bronchiolitis Obliterans	13%
114	Rhinitis, Vasomotor	12.5%
115	Scimitar Syndrome	12.4%
116	Asthma, Occupational	12%
117	Epistaxis	12%
118	Radiation Pneumonitis	11.8%
119	Radiation Fibrosis	11.8%
120	Kartagener Syndrome	11.7%
121	Asbestosis	11.5%
122	Berylliosis	11.5%
123	Silicosis	11.5%
124	Lung Injury	11.4%
125	Hepatopulmonary Syndrome	11.4%
126	Common Cold	11.3%
127	Hemothorax	11.3%
128	Influenza	11.3%
129	Catarrh	11.3%
130	Pulmonary Embolism	11.2%
131	Pulmonary Eosinophilia	11.1%
132	Severe Acute Respiratory Syndrome	11.1%
133	Eosinophilic Pneumonia	11.1%
134	Ear Diseases	11.1%
135	Respiration Disorders	11.1%
136	Farmer's Lung	10.8%
137	Epiglottitis	10.5%
138	Chronic Obstructive Airway Disease	10.5%
139	Mediastinitis	10.5%
140	Middle Lobe Syndrome	10.5%
141	Acute Lung Injury	10.5%
142	Tonsillitis	10.3%
143	Nasopharyngitis	10.3%
144	Asthma, Aspirin-Induced	10.3%
145	Vocal Cord Dysfunction	9.5%
146	Ear Neoplasms	9.4%
147	Hemoptysis	9.3%
148	Pertussis	9.2%
149	Laryngeal Diseases	9.1%
150	Pharyngeal Diseases	9.1%
151	Blastomycosis	9%
152	Retropharyngeal Abscess	8.8%
153	Pulmonary Emphysema	8.7%
154	Mediastinal Cyst	8.5%
155	Pericardial Cyst	8.5%
156	Persistent Fetal Circulation Syndrome	8.5%
157	Thymic Cyst	8.5%
158	Histiocytosis, Langerhans-Cell	8.3%
159	Labyrinthitis	8.3%
160	Mediastinal Emphysema	8.3%
161	Pulmonary Aspergillosis	8.3%
162	Bronchopulmonary Aspergillosis	8.3%
163	Sarcoidosis, Pulmonary	8.3%
164	Pulmonary Infarction	8.2%
165	Cystic Fibrosis	8.2%
166	Pharyngeal Neoplasms	8%
167	Peritonsillar Abscess	7.2%
168	Otosclerosis	7.1%
169	Tympanosclerosis	7.1%
170	Bronchopulmonary Dysplasia	6.9%
171	Laryngospasm	6.9%
172	Granulomatosis with polyangiitis	6.8%
173	Nasopharyngeal Neoplasms	6.8%
174	Tympanic Membrane Perforation	5.9%
175	Anti-Glomerular Basement Membrane Disease	5.8%
176	Hypopharyngeal Neoplasms	5.8%
177	Hypopharyngeal Cancer	5.8%
178	Bronchomalacia	5.8%
179	Tracheomalacia	5.8%
180	Transfusion-Related Acute Lung Injury	5.8%
181	Otomycosis	5.7%
182	Congenital Microtia	5.7%
183	Invasive Pulmonary Aspergillosis	5.7%
184	Deglutition Disorders	5.6%
185	Cochlear Diseases	5.3%
186	Otitis Externa	5.3%
187	Otitis Media	5.3%
188	Vestibular Diseases	5.3%
189	Endolymphatic Hydrops	5.3%
190	Nasopharyngeal carcinoma	5%
191	Tonsillar Neoplasms	4.8%
192	Dysacusis	4.6%
193	Meniere Disease	4.3%
194	Otitis Media with Effusion	4.3%
195	Eosinophilic Granuloma	4.3%
196	Vestibulocochlear Nerve Diseases	4.2%
197	Herpes Zoster Oticus	3.9%
198	Acoustic Neuroma	3.6%
199	Vestibular Neuronitis	3.4%
200	Hyperacusis	3.4%
201	Tinnitus	3.4%
202	Phonophobia	3.4%
203	Hearing Loss	3.4%
204	Lemierre Syndrome	3%
205	Vertigo	2.9%
206	Mastoiditis	2.8%
207	Petrositis	2.8%
208	Deafness	2.8%
209	Hearing Loss, Sudden	2.8%
210	Hearing Loss, Bilateral	2.8%
211	Hearing Loss, High-Frequency	2.8%
212	Hearing Loss, Mixed Conductive-Sensorineural	2.8%
213	Hearing Loss, Unilateral	2.8%
214	Complete Hearing Loss	2.8%
215	Deaf Mutism	2.8%
216	Auditory Perceptual Disorders	1.9%

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