Osteolysis
(UMLS:C4721411)
- Definition:
- Dissolution of bone that particularly involves the removal or loss of calcium.
- UMLS ID:
- C4721411
- MeSH ID:
- D010014
Classification 1:
- Musculoskeletal Diseases
- MeSH Tree Number(s):
- C05.116.264.579
Classification 2:
- Musculoskeletal and Neural Physiological Phenomena
- MeSH Tree Number(s):
- G11.427.213.150.570
Synonym(s)
1.
Osteolysis
2.
Bone dissolution
3.
Bone lysis
4.
Breakdown of bone
5.
Increased bone resorption
6.
Osteolysis, site unspecified
7.
Osteolysis, unspecified site
8.
Osteolytic defects of bones
9.
Resorption bone increased
10.
osteolysis
Associated Drug(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Zoledronic Acid | FAERS: 139 Canada Vigilance: 1 | 15867366 | CTD OFFSIDES Canada Vigilance US FAERS |
| 2 | Lenalidomide | FAERS: 37 | US FAERS | |
| 3 | Pamidronate | FAERS: 20 | US FAERS | |
| 4 | Alendronate | FAERS: 10 | OFFSIDES US FAERS | |
| 5 | Tenofovir | FAERS: 7 | OFFSIDES US FAERS | |
| 6 | Ibandronic Acid | FAERS: 6 | US FAERS | |
| 7 | Thalidomide | FAERS: 6 | 11951079 | CTD OFFSIDES US FAERS |
| 8 | Anastrozole | FAERS: 5 | OFFSIDES US FAERS | |
| 9 | Bortezomib | FAERS: 5 | US FAERS | |
| 10 | Imatinib Mesylate | FAERS: 5 | 15867366 | CTD US FAERS |
| 11 | Octreotide | FAERS: 5 | US FAERS | |
| 12 | Teriparatide | FAERS: 5 | US FAERS | |
| 13 | Everolimus | FAERS: 4 | US FAERS | |
| 14 | pomalidomide | FAERS: 4 | US FAERS | |
| 15 | Erlotinib Hydrochloride | FAERS: 3 | US FAERS | |
| 16 | Isotretinoin | FAERS: 3 | US FAERS | |
| 17 | Morphine | FAERS: 3 | US FAERS | |
| 18 | Risedronic Acid | FAERS: 3 | US FAERS | |
| 19 | Ruxolitinib phosphate | FAERS: 3 | US FAERS | |
| 20 | Sorafenib | FAERS: 3 | US FAERS | |
| 21 | Warfarin | FAERS: 3 | US FAERS | |
| 22 | miglustat | FAERS: 3 | OFFSIDES US FAERS | |
| 23 | Betamethasone | FAERS: 2 | US FAERS | |
| 24 | Letrozole | FAERS: 2 | OFFSIDES US FAERS | |
| 25 | Micafungin | FAERS: 2 | US FAERS | |
| 26 | Mirtazapine | FAERS: 2 | US FAERS | |
| 27 | PCI 32765 | FAERS: 2 | US FAERS | |
| 28 | Valsartan | FAERS: 2 | US FAERS | |
| 29 | exemestane | FAERS: 2 | OFFSIDES US FAERS | |
| 30 | lenvatinib | FAERS: 2 | US FAERS | |
| 31 | samarium Sm-153 lexidronam | FAERS: 2 | OFFSIDES US FAERS | |
| 32 | temsirolimus | FAERS: 2 | US FAERS | |
| 33 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | FAERS: 1 | US FAERS | |
| 34 | Alendronate | FAERS: 1 | US FAERS | |
| 35 | Alprazolam | FAERS: 1 | US FAERS | |
| 36 | Amlodipine | FAERS: 1 | US FAERS | |
| 37 | Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination | FAERS: 1 | US FAERS | |
| 38 | Azacitidine | FAERS: 1 | US FAERS | |
| 39 | Baclofen | FAERS: 1 | US FAERS | |
| 40 | Bosentan | FAERS: 1 | US FAERS | |
| 41 | Busulfan | FAERS: 1 | US FAERS | |
| 42 | Cabozantinib S-malate | FAERS: 1 | US FAERS | |
| 43 | Capecitabine | FAERS: 1 | US FAERS | |
| 44 | Carbamazepine | FAERS: 1 | OFFSIDES US FAERS | |
| 45 | Cinacalcet | FAERS: 1 | US FAERS | |
| 46 | Crizotinib | FAERS: 1 | US FAERS | |
| 47 | Deferoxamine | FAERS: 1 | US FAERS | |
| 48 | Didanosine | FAERS: 1 | OFFSIDES US FAERS | |
| 49 | Erlotinib Hydrochloride | FAERS: 1 | US FAERS | |
| 50 | F8 protein, human | FAERS: 1 | US FAERS | |
| 51 | Fentanyl | FAERS: 1 | OFFSIDES US FAERS | |
| 52 | Fingolimod Hydrochloride | FAERS: 1 | US FAERS | |
| 53 | Fluticasone-Salmeterol Drug Combination | FAERS: 1 | US FAERS | |
| 54 | Fluticasone | FAERS: 1 | US FAERS | |
| 55 | Fluvastatin | FAERS: 1 | US FAERS | |
| 56 | Fosamax | FAERS: 1 | US FAERS | |
| 57 | Fractals | FAERS: 1 | US FAERS | |
| 58 | Furosemide | FAERS: 1 | US FAERS | |
| 59 | Gabapentin | FAERS: 1 | OFFSIDES US FAERS | |
| 60 | Ibandronic Acid | FAERS: 1 | US FAERS | |
| 61 | Insulin Detemir | FAERS: 1 | US FAERS | |
| 62 | Methimazole | FAERS: 1 | US FAERS | |
| 63 | Methotrexate | FAERS: 1 | US FAERS | |
| 64 | Pantoprazole | FAERS: 1 | US FAERS | |
| 65 | Rivastigmine | FAERS: 1 | US FAERS | |
| 66 | Salmeterol Xinafoate | FAERS: 1 | US FAERS | |
| 67 | Sildenafil Citrate | FAERS: 1 | OFFSIDES US FAERS | |
| 68 | Sodium risedronate hydrate | FAERS: 1 | US FAERS | |
| 69 | Sunitinib | FAERS: 1 | US FAERS | |
| 70 | Tacrolimus | FAERS: 1 | US FAERS | |
| 71 | Triamcinolone | FAERS: 1 | OFFSIDES US FAERS | |
| 72 | Vemurafenib | FAERS: 1 | US FAERS | |
| 73 | Voriconazole | FAERS: 1 | US FAERS | |
| 74 | Warfarin | FAERS: 1 | US FAERS | |
| 75 | apixaban | FAERS: 1 | US FAERS | |
| 76 | pazopanib | FAERS: 1 | US FAERS | |
| 77 | rofecoxib | FAERS: 1 | US FAERS | |
| 78 | salmon calcitonin | FAERS: 1 | US FAERS | |
| 79 | tofacitinib | FAERS: 1 | US FAERS | |
| 80 | Acitretin | OFFSIDES | ||
| 81 | Acyclovir | OFFSIDES | ||
| 82 | Allopurinol | OFFSIDES | ||
| 83 | Amantadine | OFFSIDES | ||
| 84 | Amifostine | OFFSIDES | ||
| 85 | Amisulpride | OFFSIDES | ||
| 86 | Ampicillin | OFFSIDES | ||
| 87 | Ascorbic Acid | OFFSIDES | ||
| 88 | Atovaquone | OFFSIDES | ||
| 89 | Bezafibrate | OFFSIDES | ||
| 90 | Biotin | OFFSIDES | ||
| 91 | Bisacodyl | OFFSIDES | ||
| 92 | Bisoprolol | OFFSIDES | ||
| 93 | Brimonidine Tartrate | OFFSIDES | ||
| 94 | Budesonide | OFFSIDES | ||
| 95 | Bumetanide | OFFSIDES | ||
| 96 | Bupropion | OFFSIDES | ||
| 97 | Buspirone | OFFSIDES | ||
| 98 | Calcitriol | OFFSIDES | ||
| 99 | Calcium Chloride | OFFSIDES | ||
| 100 | Calcium Citrate | OFFSIDES | ||
| 101 | Calcium Compounds | OFFSIDES | ||
| 102 | Carboplatin | OFFSIDES | ||
| 103 | Carboxymethylcellulose Sodium | OFFSIDES | ||
| 104 | Carvedilol | OFFSIDES | ||
| 105 | Cefazolin | OFFSIDES | ||
| 106 | Cefepime | OFFSIDES | ||
| 107 | Cefoxitin | OFFSIDES | ||
| 108 | Ceftriaxone | OFFSIDES | ||
| 109 | Celecoxib | 14585714 | CTD OFFSIDES | |
| 110 | Cephalexin | OFFSIDES | ||
| 111 | Chlorhexidine | OFFSIDES | ||
| 112 | Cinacalcet | OFFSIDES | ||
| 113 | Ciprofloxacin | OFFSIDES | ||
| 114 | Cisapride | OFFSIDES | ||
| 115 | Clindamycin | OFFSIDES | ||
| 116 | Clodronic Acid | OFFSIDES | ||
| 117 | Clopenthixol | OFFSIDES | ||
| 118 | Clotrimazole | OFFSIDES | ||
| 119 | Cocaine | 3334775 | CTD | |
| 120 | Cortisone | OFFSIDES | ||
| 121 | Cortisone | OFFSIDES | ||
| 122 | Cyclophosphamide | OFFSIDES | ||
| 123 | Cyclosporine | OFFSIDES | ||
| 124 | Dacarbazine | OFFSIDES | ||
| 125 | Desoximetasone | OFFSIDES | ||
| 126 | Dexamethasone | OFFSIDES | ||
| 127 | Diane | OFFSIDES | ||
| 128 | Diazepam | OFFSIDES | ||
| 129 | Dicloxacillin | OFFSIDES | ||
| 130 | Dioctyl Sulfosuccinic Acid | OFFSIDES | ||
| 131 | Diphenoxylate | OFFSIDES | ||
| 132 | Dipyridamole | OFFSIDES | ||
| 133 | Docetaxel | 18606716 | CTD OFFSIDES | |
| 134 | Docusate sodium | OFFSIDES | ||
| 135 | Doxorubicin | OFFSIDES | ||
| 136 | Doxycycline | OFFSIDES | ||
| 137 | Dutasteride | OFFSIDES | ||
| 138 | Econazole | OFFSIDES | ||
| 139 | Ertapenem | OFFSIDES | ||
| 140 | Erythromycin | OFFSIDES | ||
| 141 | Estrogens, Conjugated (USP) | OFFSIDES | ||
| 142 | Ethosuximide | OFFSIDES | ||
| 143 | Etidronic Acid | SIDER | ||
| 144 | Etodolac | OFFSIDES | ||
| 145 | Etomidate | OFFSIDES | ||
| 146 | Famotidine | OFFSIDES | ||
| 147 | Fludrocortisone | OFFSIDES | ||
| 148 | Fosinopril | OFFSIDES | ||
| 149 | Fulvestrant | OFFSIDES | ||
| 150 | Gatifloxacin | OFFSIDES | ||
| 151 | Goserelin | OFFSIDES | ||
| 152 | Hydrochlorothiazide | OFFSIDES | ||
| 153 | Hydrocortisone | OFFSIDES | ||
| 154 | Hydron;carbonate | OFFSIDES | ||
| 155 | Ibuprofen | OFFSIDES | ||
| 156 | Ifosfamide | OFFSIDES | ||
| 157 | Isradipine | OFFSIDES | ||
| 158 | Itraconazole | OFFSIDES | ||
| 159 | Ketoconazole | OFFSIDES | ||
| 160 | Ketorolac | OFFSIDES | ||
| 161 | Ketorolac Tromethamine | OFFSIDES | ||
| 162 | Latanoprost | OFFSIDES | ||
| 163 | Levobunolol | OFFSIDES | ||
| 164 | Linezolid | OFFSIDES | ||
| 165 | Linsidomine | OFFSIDES | ||
| 166 | Lopinavir/Ritonavir | OFFSIDES | ||
| 167 | Lubiprostone | OFFSIDES | ||
| 168 | Melatonin | OFFSIDES | ||
| 169 | Melphalan | OFFSIDES | ||
| 170 | Meperidine | OFFSIDES | ||
| 171 | Methocarbamol | OFFSIDES | ||
| 172 | Methylphenidate | OFFSIDES | ||
| 173 | Methylprednisolone Acetate | OFFSIDES | ||
| 174 | Methylprednisolone Hemisuccinate | OFFSIDES | ||
| 175 | Methyltestosterone | OFFSIDES | ||
| 176 | Metolazone | OFFSIDES | ||
| 177 | Metronidazole | OFFSIDES | ||
| 178 | Midodrine | OFFSIDES | ||
| 179 | Mitoxantrone | OFFSIDES | ||
| 180 | Modafinil | OFFSIDES | ||
| 181 | Moxifloxacin | OFFSIDES | ||
| 182 | Mupirocin | OFFSIDES | ||
| 183 | Mycophenolic Acid | OFFSIDES | ||
| 184 | Nabumetone | OFFSIDES | ||
| 185 | Naloxone | OFFSIDES | ||
| 186 | Neostigmine | OFFSIDES | ||
| 187 | Niacin | OFFSIDES | ||
| 188 | Nizatidine | OFFSIDES | ||
| 189 | Nortriptyline | OFFSIDES | ||
| 190 | NuvaRing | OFFSIDES | ||
| 191 | Olmesartan Medoxomil | OFFSIDES | ||
| 192 | Omeprazole | OFFSIDES | ||
| 193 | Orphenadrine | OFFSIDES | ||
| 194 | Oseltamivir | OFFSIDES | ||
| 195 | Paclitaxel | 15867366 | CTD OFFSIDES | |
| 196 | Pamidronate | 11951079 12507583 | CTD OFFSIDES | |
| 197 | Paroxetine | OFFSIDES | ||
| 198 | Penicillamine | OFFSIDES | ||
| 199 | Penicillin V | OFFSIDES | ||
| 200 | Pilocarpine | OFFSIDES | ||
| 201 | Piperacillin, Tazobactam Drug Combination | OFFSIDES | ||
| 202 | Piperacillin | OFFSIDES | ||
| 203 | Polymyxin B | OFFSIDES | ||
| 204 | Potassium | OFFSIDES | ||
| 205 | Potassium Citrate | OFFSIDES | ||
| 206 | Povidone-Iodine | OFFSIDES | ||
| 207 | Pravastatin | OFFSIDES | ||
| 208 | Pregabalin | OFFSIDES | ||
| 209 | Primidone | OFFSIDES | ||
| 210 | Prochlorperazine | OFFSIDES | ||
| 211 | Progesterone | OFFSIDES | ||
| 212 | Propafenone | OFFSIDES | ||
| 213 | Quinidine | OFFSIDES | ||
| 214 | Raloxifene Hydrochloride | OFFSIDES | ||
| 215 | Risedronic Acid | OFFSIDES | ||
| 216 | Rosiglitazone | OFFSIDES | ||
| 217 | Scopolamine | OFFSIDES | ||
| 218 | Selenium | OFFSIDES | ||
| 219 | Sertraline | OFFSIDES | ||
| 220 | Sevelamer | OFFSIDES | ||
| 221 | Sevelamer | OFFSIDES | ||
| 222 | Simethicone | OFFSIDES | ||
| 223 | Simvastatin | 21199873 | CTD | |
| 224 | Sulfadiazine | OFFSIDES | ||
| 225 | Sulfamethoxazole | OFFSIDES | ||
| 226 | Sumatriptan | OFFSIDES | ||
| 227 | Tamoxifen | OFFSIDES | ||
| 228 | Tazobactam | OFFSIDES | ||
| 229 | Temozolomide | OFFSIDES | ||
| 230 | Tenofovir | OFFSIDES | ||
| 231 | Terazosin | OFFSIDES | ||
| 232 | Thiamine | OFFSIDES | ||
| 233 | Thiotepa | OFFSIDES | ||
| 234 | Tobramycin | OFFSIDES | ||
| 235 | Toremifene | OFFSIDES | ||
| 236 | Tramadol | OFFSIDES | ||
| 237 | Tretinoin | OFFSIDES | ||
| 238 | Triamterene | OFFSIDES | ||
| 239 | Triiodothyronine | OFFSIDES | ||
| 240 | Ubiquinone | OFFSIDES | ||
| 241 | Vinblastine | OFFSIDES | ||
| 242 | Vincristine | OFFSIDES | ||
| 243 | Vinorelbine | OFFSIDES | ||
| 244 | Vitamin B 12 | OFFSIDES | ||
| 245 | Vitamin D | OFFSIDES | ||
| 246 | Vitamin E | 19781538 | CTD OFFSIDES | |
| 247 | abacavir, lamivudine drug combination | OFFSIDES | ||
| 248 | abacavir | OFFSIDES | ||
| 249 | adefovir dipivoxil | OFFSIDES | ||
| 250 | alfacalcidol | OFFSIDES | ||
| 251 | alfuzosin | OFFSIDES | ||
| 252 | alpha-Tocopherol | OFFSIDES | ||
| 253 | amezinium | OFFSIDES | ||
| 254 | anagrelide | OFFSIDES | ||
| 255 | azelastine | OFFSIDES | ||
| 256 | bicalutamide | OFFSIDES | ||
| 257 | brinzolamide | OFFSIDES | ||
| 258 | buflomedil | OFFSIDES | ||
| 259 | calcium acetate | OFFSIDES | ||
| 260 | carbidopa, levodopa drug combination | OFFSIDES | ||
| 261 | cefprozil | OFFSIDES | ||
| 262 | cefuroxime axetil | OFFSIDES | ||
| 263 | cevimeline | OFFSIDES | ||
| 264 | chlordiazepoxide, clidinium drug combination | OFFSIDES | ||
| 265 | chlorhexidine gluconate | OFFSIDES | ||
| 266 | ciclesonide | OFFSIDES | ||
| 267 | deflazacort | OFFSIDES | ||
| 268 | diflucortolone valerate | OFFSIDES | ||
| 269 | dolasetron | OFFSIDES | ||
| 270 | doxifluridine | OFFSIDES | ||
| 271 | fexofenadine | OFFSIDES | ||
| 272 | fosphenytoin | OFFSIDES | ||
| 273 | gemcitabine | OFFSIDES | ||
| 274 | metaxalone | OFFSIDES | ||
| 275 | moexipril | OFFSIDES | ||
| 276 | pirbuterol | OFFSIDES | ||
| 277 | propoxyphene napsylate | OFFSIDES | ||
| 278 | ramelteon | OFFSIDES | ||
| 279 | repaglinide | OFFSIDES | ||
| 280 | reslin | OFFSIDES | ||
| 281 | rizatriptan | OFFSIDES | ||
| 282 | rizatriptan | OFFSIDES | ||
| 283 | tizanidine | OFFSIDES | ||
| 284 | valdecoxib | OFFSIDES | ||
| 285 | zafirlukast | OFFSIDES |
Similar ADE(s)
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