MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Croup

(UMLS:C0010380)

Definition:: Inflammation involving the GLOTTIS or VOCAL CORDS and the subglottic larynx. Croup is characterized by a barking cough, HOARSENESS, and persistent inspiratory STRIDOR (a high-pitched breathing sound). It occurs chiefly in infants and children.
UMLS ID:: C0010380
MeSH ID:: D003440

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.360.535.365

Classification 2:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.400.535.365

Synonym(s)

Croup

Acute Obstructive Laryngitis

Acute laryngotracheobronchitis

Acute obstructive laryngitis [croup]

CROUP

Croup syndrome

Laryngotracheitis

Laryngotracheobronchitis

acute laryngotracheobronchitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Epinephrine		10390295	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Laryngeal Edema	31%
2	Vocal Cord Dysfunction	29.2%
3	Laryngostenosis	24.7%
4	Laryngocele	24.1%
5	Laryngeal neoplasm	23.6%
6	Granuloma, Laryngeal	22.4%
7	Voice Disorders	20.7%
8	Voice Disturbance	20.7%
9	Laryngospasm	18.7%
10	Nose Diseases	18.5%
11	Laryngomalacia	17.6%
12	Vocal Cord Paralysis	17.4%
13	Laryngopharyngeal Reflux	15%
14	Aphonia	13.3%
15	Dysphonia	13.3%
16	Hoarseness	12.6%
17	Rhinitis	12.5%
18	Bronchial Diseases	11.9%
19	Ear Diseases	11.9%
20	Lung diseases	11.9%
21	Pleural Diseases	11.9%
22	Respiration Disorders	11.9%
23	Thoracic Diseases	11.9%
24	Tracheal Diseases	11.9%
25	Primary Ciliary Dyskinesia	11.8%
26	Bronchitis	11%
27	Choanal Atresia	10.3%
28	Granuloma, Lethal Midline	10.3%
29	Nose Deformities, Acquired	10.3%
30	Pleurisy	10.3%
31	Pneumonia	10.3%
32	Lobar Pneumonia	10.3%
33	Respiratory Distress Syndrome, Adult	10.3%
34	Tracheitis	10.3%
35	Tracheobronchomegaly	10.3%
36	Pneumonitis	10.3%
37	Bronchopneumonia	9.5%
38	Sinusitis	9.5%
39	Pharyngeal Diseases	9.3%
40	Nose Neoplasms	9.1%
41	Asthma	9%
42	Respiratory Tract Infections	8.9%
43	Pleuropneumonia	8.9%
44	Paranasal Sinus Neoplasms	8.8%
45	Granuloma, Respiratory Tract	8.8%
46	Respiratory Hypersensitivity	8.8%
47	Respiratory Tract Fistula	8.8%
48	Lung Diseases, Fungal	8.3%
49	Pharyngitis	8.3%
50	Nasal Polyps	8.2%
51	Respiratory Distress Syndrome, Newborn	8.2%
52	Bronchial Fistula	8.2%
53	Ear Neoplasms	8.2%
54	Lung Abscess	8.2%
55	Lung Neoplasms	8.2%
56	Pleural Neoplasms	8.2%
57	Tuberculosis, Pulmonary	8.1%
58	Bronchitis, Chronic	7.7%
59	Bronchiolitis	7.3%
60	Pharyngeal Neoplasms	6.9%
61	Altitude Sickness	6.8%
62	Atelectasis	6.8%
63	Bronchospasm	6.8%
64	Bronchiectasis	6.8%
65	Chylothorax	6.8%
66	Epistaxis	6.8%
67	Hydropneumothorax	6.8%
68	Hydrothorax	6.8%
69	Pulmonary Hypertension	6.8%
70	Otosclerosis	6.8%
71	Pneumothorax	6.8%
72	Pulmonary Alveolar Proteinosis	6.8%
73	Pulmonary Edema	6.8%
74	Pulmonary Fibrosis	6.8%
75	Respiratory Insufficiency	6.8%
76	Tracheal Stenosis	6.8%
77	Bronchial Hyperreactivity	6.8%
78	Hamman-Rich syndrome	6.8%
79	Lung Diseases, Interstitial	6.8%
80	Respiratory Depression	6.8%
81	Tympanosclerosis	6.8%
82	Lung Diseases, Obstructive	6.8%
83	Respiratory Failure	6.8%
84	Tracheal Neoplasms	6.8%
85	Rhinoscleroma	6.7%
86	Bronchial Neoplasms	6.7%
87	Labyrinthitis	6.7%
88	Aspiration Pneumonia	6.7%
89	Rhinitis, Vasomotor	6.7%
90	Pleural Effusion, Malignant	6.6%
91	Maxillary Sinus Neoplasms	6.5%
92	Aspergillosis, Allergic Bronchopulmonary	6.2%
93	Idiopathic Pulmonary Fibrosis	5.8%
94	Nasopharyngitis	5.7%
95	Pneumoconiosis	5.6%
96	Pneumonia, Viral	5.6%
97	Hay fever	5.4%
98	Rhinitis, Allergic, Perennial	5.4%
99	Pneumonia, Bacterial	5.4%
100	Tympanic Membrane Perforation	5.4%
101	Tonsillitis	5.3%
102	Hyaline Membrane Disease	5.3%
103	Asthma, Exercise-Induced	5.3%
104	Status Asthmaticus	5.3%
105	Multiple Pulmonary Nodules	5.3%
106	Kartagener Syndrome	5.3%
107	Otomycosis	5.2%
108	Lung Injury	5.2%
109	Hepatopulmonary Syndrome	5.2%
110	Respiratory Aspiration	5.2%
111	Congenital Microtia	5.2%
112	Scimitar Syndrome	5.1%
113	Apnea	5.1%
114	Cheyne-Stokes Respiration	5.1%
115	Common Cold	5.1%
116	Deglutition Disorders	5.1%
117	Dyspnea	5.1%
118	Hemothorax	5.1%
119	Hyperventilation	5.1%
120	Influenza	5.1%
121	Mouth Breathing	5.1%
122	Tachypnea	5.1%
123	Catarrh	5.1%
124	Pulmonary Embolism	5%
125	Pulmonary Eosinophilia	5%
126	Severe Acute Respiratory Syndrome	5%
127	Eosinophilic Pneumonia	5%
128	Acute Chest Syndrome	5%
129	Nasopharyngeal Neoplasms	5%
130	Pneumonia, Lipid	4.9%
131	Meconium Aspiration Syndrome	4.9%
132	Asthma, Occupational	4.6%
133	Bronchiolitis Obliterans	4.5%
134	Radiation Pneumonitis	4.5%
135	Radiation Fibrosis	4.5%
136	Airway Obstruction	4.4%
137	Choking	4.4%
138	Cochlear Diseases	4.4%
139	Epiglottitis	4.4%
140	Chronic Obstructive Airway Disease	4.4%
141	Mediastinitis	4.4%
142	Middle Lobe Syndrome	4.4%
143	Otitis Externa	4.4%
144	Otitis Media	4.4%
145	Vestibular Diseases	4.4%
146	Endolymphatic Hydrops	4.4%
147	Acute Lung Injury	4.4%
148	Retropharyngeal Abscess	4.4%
149	Hypopharyngeal Neoplasms	4.4%
150	Hypopharyngeal Cancer	4.4%
151	Laryngitis	4.2%
152	Hemoptysis	4.1%
153	Pertussis	4%
154	Dysacusis	4%
155	Asbestosis	4%
156	Berylliosis	4%
157	Silicosis	4%
158	Farmer's Lung	3.9%
159	Asthma, Aspirin-Induced	3.8%
160	Cystic Fibrosis	3.5%
161	Vestibulocochlear Nerve Diseases	3.4%
162	Mediastinal Cyst	3.4%
163	Pericardial Cyst	3.4%
164	Persistent Fetal Circulation Syndrome	3.4%
165	Thymic Cyst	3.4%
166	Herpes Zoster Oticus	3.3%
167	Histiocytosis, Langerhans-Cell	3.3%
168	Mediastinal Emphysema	3.3%
169	Pulmonary Aspergillosis	3.3%
170	Bronchopulmonary Aspergillosis	3.3%
171	Hypoventilation	3.3%
172	Acidosis, Respiratory	3.3%
173	Alkalosis, Respiratory	3.3%
174	Blastomycosis	3.3%
175	Sarcoidosis, Pulmonary	3.3%
176	Sleep Apnea Syndromes	3.3%
177	Meniere Disease	3.3%
178	Otitis Media with Effusion	3.3%
179	Pulmonary Emphysema	3.3%
180	Pulmonary Infarction	3.3%
181	Peritonsillar Abscess	3.3%
182	Tonsillar Neoplasms	3.2%
183	Nasopharyngeal carcinoma	3.2%
184	Acoustic Neuroma	2.7%
185	Dyspnea, Paroxysmal	2.6%
186	Respiratory Paralysis	2.6%
187	Granulomatosis with polyangiitis	2.6%
188	Hyperacusis	2.6%
189	Tinnitus	2.6%
190	Phonophobia	2.6%
191	Hearing Loss	2.6%
192	Bronchopulmonary Dysplasia	2.5%
193	Vestibular Neuronitis	2.5%
194	Lemierre Syndrome	2.5%
195	Sleep Apnea, Obstructive	2.4%
196	Sleep Apnea, Central	2.4%
197	Anti-Glomerular Basement Membrane Disease	2.2%
198	Bronchomalacia	2.2%
199	Tracheomalacia	2.2%
200	Vertigo	2%
201	Transfusion-Related Acute Lung Injury	2%
202	Invasive Pulmonary Aspergillosis	2%
203	Mastoiditis	2%
204	Petrositis	2%
205	Deafness	1.9%
206	Hearing Loss, Sudden	1.9%
207	Hearing Loss, Bilateral	1.9%
208	Hearing Loss, High-Frequency	1.9%
209	Hearing Loss, Mixed Conductive-Sensorineural	1.9%
210	Hearing Loss, Unilateral	1.9%
211	Complete Hearing Loss	1.9%
212	Deaf Mutism	1.9%
213	Eosinophilic Granuloma	1.4%
214	Auditory Perceptual Disorders	1.2%

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