MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Osteoarthritis, Spine

(UMLS:C2350242)

Definition:: A degenerative joint disease involving the SPINE. It is characterized by progressive deterioration of the spinal articular cartilage (CARTILAGE, ARTICULAR), usually with hardening of the subchondral bone and outgrowth of bone spurs (OSTEOPHYTE).
UMLS ID:: C2350242
MeSH ID:: D055013

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.900.853.625.399|C05.550.114.606.750|C05.550.114.865.399|C05.799.613.750

Synonym(s)

Osteoarthritis, Spine

OA - Osteoarthritis of spine

OA - Osteoarthritis of the spine

OSTEOARTHRITIS SPINAL

Osteoarthritis of spine

Osteoarthritis;spine

Spinal osteoarthritis

osteoarthrosis; spine

spine; osteoarthrosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Pentazocine		6477021	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Osteoarthritis, Knee	46.1%
2	Spondylarthropathies	45.7%
3	Arthritis, Psoriatic	45.6%
4	Ankylosing spondylitis	41.1%
5	Periarthritis	39.8%
6	Arthritis, Reactive	39.2%
7	Osteoarthropathy, Secondary Hypertrophic	39%
8	Gout	38.6%
9	Rheumatic Fever	38.1%
10	Arthrogryposis	34.3%
11	Contracture	34%
12	Rheumatoid Arthritis	33.8%
13	Juvenile arthritis	33.8%
14	Sacroiliitis	31.6%
15	Metatarsalgia	29%
16	Bursitis	26.7%
17	Joint Instability	26.7%
18	Synovitis	26.7%
19	Joint laxity	26.7%
20	Frozen shoulder	26.7%
21	Patellofemoral Pain Syndrome	26.7%
22	Arthritis, Infectious	26.7%
23	Arthritis, Experimental	26.4%
24	Fibromyalgia	25.3%
25	Polymyalgia Rheumatica	25.3%
26	Arthritis, Gouty	25%
27	Fasciitis	24.7%
28	Foot Deformities	24.7%
29	Rheumatoid Nodule	24.6%
30	Osteochondritis	23.9%
31	Platybasia	23.5%
32	Temporomandibular Joint Disorders	23%
33	Fasciitis, Plantar	22.8%
34	Hemarthrosis	22.3%
35	Pectus carinatum	21.7%
36	Felty Syndrome	21.6%
37	Jaw Diseases	21.3%
38	Spinal Neoplasms	21.1%
39	Cartilage Diseases	20.8%
40	Foot Diseases	20.8%
41	Myopathy	20.8%
42	Chondromalacia	20.8%
43	Osteoarthritis, Spine	20.6%
44	Ischemic contracture	20.3%
45	Hip Contracture	20.2%
46	Bone Diseases, Developmental	19.5%
47	Hyperostosis	19.5%
48	Osteitis	19.5%
49	Osteitis Deformans	19.5%
50	Osteochondrosis	19.5%
51	Rheumatoid Vasculitis	19.2%
52	Bone Diseases	19%
53	Discitis	18.9%
54	Pectus excavatum	18%
55	Spinal Stenosis	17.9%
56	Spondylosis	17.9%
57	Intervertebral Disc Degeneration	17.9%
58	Sicca Syndrome	17.3%
59	Sjogren's Syndrome	17.3%
60	Temporomandibular Joint Dysfunction Syndrome	17%
61	Nail-Patella Syndrome	16.9%
62	Bone Diseases, Endocrine	16.8%
63	Arthralgia	16.6%
64	Polyarthralgia	16.6%
65	Tuberculosis, Spinal	16.5%
66	Bone Diseases, Infectious	16.4%
67	Bone neoplasms	16.4%
68	Osteopenia	16.4%
69	Gigantism	16.4%
70	Bone Resorption	16.3%
71	Aseptic Necrosis of Bone	16.3%
72	Rheumatism	15.1%
73	Klippel-Feil Syndrome	15.1%
74	Synostosis	15.1%
75	Myofascial Pain Syndromes	13.5%
76	Rhabdomyolysis	13.5%
77	Spondylitis	12.9%
78	Talipes	12.8%
79	Arthropathy	12.5%
80	Craniosynostosis	12.1%
81	Syndactyly	12.1%
82	Brachycephaly	12.1%
83	Hip Dislocation	11.7%
84	Shoulder Dislocation	11.7%
85	Hip Dysplasia	11.7%
86	Compartment syndromes	11.4%
87	Maxillary Diseases	11.4%
88	Tendinitis	11.4%
89	Tendinopathy	11.4%
90	Ainhum	11.4%
91	Dysostoses	11.4%
92	Lordosis	11.3%
93	Spondylolysis	11.3%
94	kyphosis	11.3%
95	Myositis	11.3%
96	Tietze's Syndrome	11.3%
97	Limb Deformities, Congenital	11.3%
98	Isaacs syndrome	11.3%
99	Craniofacial Abnormalities	11.3%
100	Myotonic Disorders	11.3%
101	Craniofacial Dysostosis	11.1%
102	Acrocephalosyndactylia	11%
103	Eosinophilic Granuloma	10.7%
104	Congenital Hypothyroidism	10.6%
105	Spinal Diseases	10.6%
106	Shoulder Pain	9.9%
107	Medial Tibial Stress Syndrome	9.8%
108	Mitochondrial Myopathies	9.7%
109	Muscle Cramp	9.6%
110	Eosinophilia-Myalgia Syndrome	9.6%
111	Gastroschisis	9.6%
112	Multiple Epiphyseal Dysplasia	9.6%
113	Osteochondrodysplasias	9.6%
114	Muscle Rigidity	9.6%
115	Muscle Spasticity	9.6%
116	Cogwheel Rigidity	9.6%
117	Nuchal Rigidity	9.6%
118	Jaw Abnormalities	9.6%
119	Osteomyelitis	9.5%
120	Osteoporosis	9.5%
121	Periostitis	9.5%
122	Bone Demineralization, Pathologic	9.5%
123	Post-Traumatic Osteoporosis	9.5%
124	Alveolar Bone Loss	9.5%
125	Femur Head Necrosis	9.5%
126	Osteolysis	9.5%
127	Congenital clubfoot	9%
128	Vertical Talus	9%
129	Chronic Fatigue Syndrome	8.8%
130	Poland Syndrome	8.6%
131	Prognathism	8.5%
132	Giant Cell Epulis	8.5%
133	Muscle Weakness	8.5%
134	Dwarfism	8.5%
135	Musculoskeletal Pain	8.5%
136	Familial Periodic Paralysis	8.4%
137	Bunion	8.1%
138	Fibrodysplasia Ossificans Progressiva	8.1%
139	Myoglobinuria	8.1%
140	Myositis Ossificans	8.1%
141	Tenosynovitis	8.1%
142	Acromegaly	8.1%
143	Joint Tuberculosis	8.1%
144	Tuberculosis, Osteoarticular	8.1%
145	Bone Tuberculosis	8.1%
146	Spondylolisthesis	8.1%
147	Laryngomalacia	7.7%
148	Antley-Bixler Syndrome Phenotype	7.6%
149	Myalgia	7.5%
150	Chondrodysplasia Punctata	7.4%
151	Enchondromatosis	7.4%
152	Osteosclerosis	7.4%
153	Kashin-Beck Disease	7.4%
154	Rickets	7.1%
155	Rubinstein-Taybi Syndrome	7.1%
156	Arthritis	6.9%
157	Polyarthritis	6.9%
158	Mandibulofacial Dysostosis	6.9%
159	Palatal Neoplasms	6.8%
160	Anterior Compartment Syndrome	6.8%
161	Enthesopathy	6.8%
162	Abdominal Compartment Syndrome	6.8%
163	Amelia	6.8%
164	Arachnodactyly	6.8%
165	Ectromelia	6.8%
166	Hemimelia	6.8%
167	Phocomelia	6.8%
168	Sirenomelia	6.8%
169	Polymyositis	6.8%
170	Polydactyly	6.8%
171	Brachydactyly	6.8%
172	Plagiocephaly	6.8%
173	Lower Extremity Deformities, Congenital	6.8%
174	Upper Extremity Deformities, Congenital	6.8%
175	Basal Cell Nevus Syndrome	6.5%
176	Pseudohypoparathyroidism	6.4%
177	Myotonic Dystrophy	6.2%
178	Osteoporosis, Postmenopausal	6.2%
179	Goldenhar Syndrome	6.2%
180	Micrognathism	6.1%
181	Pierre Robin Syndrome	6.1%
182	Muscular Dystrophy	5.9%
183	Orbital Myositis	5.9%
184	Dupuytren Contracture	5.9%
185	Pyomyositis	5.8%
186	Retrognathia	5.6%
187	Melorheostosis	5.5%
188	Osteopetrosis	5.5%
189	Osteogenesis Imperfecta	5.4%
190	Mastoiditis	5.3%
191	Petrositis	5.3%
192	Marfan Syndrome	5.3%
193	Maxillofacial Abnormalities	5.2%
194	Myotonia Congenita	5.1%
195	Bronchomalacia	5.1%
196	Tracheomalacia	5.1%
197	Microcephaly	5.1%
198	Macrocephaly	5.1%
199	Hypokalemic periodic paralysis	5.1%
200	Cleft Palate	4.7%
201	Osteomalacia	4.6%
202	Mitochondrial Encephalomyopathies	4.5%
203	Noonan Syndrome	4.1%
204	Welander Distal Myopathy	3.9%
205	Cockayne Syndrome	3.8%
206	Holoprosencephaly	3.7%
207	Dermatomyositis	3.5%
208	Nose Neoplasms	3.5%
209	Muscular Dystrophy, Duchenne	3.5%
210	Porencephaly	3.4%
211	Renal Osteodystrophy	3.4%
212	Renal rickets	3.4%
213	Radicular Cyst	2.3%
214	MELAS Syndrome	2.1%
215	Kearns-Sayre syndrome	2%
216	Familial Hypophosphatemic Rickets	1.7%

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