MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pertussis

(UMLS:C0043167)

Definition:: A respiratory infection caused by BORDETELLA PERTUSSIS and characterized by paroxysmal coughing ending in a prolonged crowing intake of breath.
UMLS ID:: C0043167
MeSH ID:: D014917

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.400.143.740|C01.539.739.969

Classification 2:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.730.969

Synonym(s)

Pertussis

Bordetella; pertussis, whooping cough

Infection due to Bordetella pertussis

WC - Whooping cough

Whooping Cough

Whooping cough

Whooping cough due to Bordetella pertussis

Whooping cough due to bordetella pertussis [B. pertussis]

bordetella caused disease pertussis

10.

disease caused by bordetella pertussis

11.

infection; Bordetella pertussis

12.

pertussis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Dimethyl Fumarate	FAERS: 5	US FAERS
2	Fingolimod Hydrochloride	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
3	Teriparatide	FAERS: 4	US FAERS
4	Zoledronic Acid	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
5	ambrisentan	FAERS: 4	US FAERS
6	tofacitinib	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
7	Budesonide	FAERS: 3	US FAERS
8	Lenalidomide	FAERS: 3	US FAERS
9	Moxifloxacin	FAERS: 3	US FAERS
10	Pregabalin	FAERS: 3	US FAERS
11	Ramipril	FAERS: 3	US FAERS
12	apixaban	FAERS: 3	US FAERS
13	4-hydroxybutyric acid	FAERS: 2	US FAERS
14	Estrogens, Conjugated (USP)	FAERS: 2	US FAERS
15	Fluticasone	FAERS: 2	US FAERS
16	Imatinib Mesylate	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
17	Liraglutide	FAERS: 2	US FAERS
18	Omeprazole	FAERS: 2	US FAERS
19	Rivaroxaban	FAERS: 2	US FAERS
20	Thalidomide	FAERS: 2	US FAERS
21	Varenicline	FAERS: 2	US FAERS
22	apremilast	FAERS: 2	US FAERS
23	carfilzomib	FAERS: 2	US FAERS
24	eliglustat	FAERS: 2	US FAERS
25	idelalisib	FAERS: 2 Canada Vigilance: 1	Canada Vigilance US FAERS
26	4-Aminopyridine	FAERS: 1	US FAERS
27	Albuterol	FAERS: 1	US FAERS
28	Amoxicillin-Potassium Clavulanate Combination	FAERS: 1	US FAERS
29	Bortezomib	FAERS: 1	US FAERS
30	Bosentan	FAERS: 1	US FAERS
31	CH5424802	FAERS: 1	US FAERS
32	Carbamazepine	FAERS: 1	US FAERS
33	Celecoxib	FAERS: 1	US FAERS
34	Ciprofloxacin	FAERS: 1	US FAERS
35	Clonazepam	FAERS: 1	US FAERS
36	Deferasirox	FAERS: 1	US FAERS
37	Doxazosin	FAERS: 1	US FAERS
38	Erythromycin	FAERS: 1	OFFSIDES US FAERS
39	Everolimus	FAERS: 1	US FAERS
40	Famotidine	FAERS: 1	US FAERS
41	Fluoxetine	FAERS: 1	US FAERS
42	Glatiramer Acetate	FAERS: 1	US FAERS
43	Isotretinoin	FAERS: 1	US FAERS
44	Lamotrigine	FAERS: 1	OFFSIDES US FAERS
45	Letrozole	FAERS: 1	OFFSIDES US FAERS
46	Levofloxacin	FAERS: 1	US FAERS
47	Lisinopril	FAERS: 1	US FAERS
48	Mesalamine	FAERS: 1	US FAERS
49	Methotrexate	FAERS: 1	US FAERS
50	Methylphenidate	FAERS: 1	US FAERS
51	Norgestrel	FAERS: 1	US FAERS
52	Ondansetron	FAERS: 1	US FAERS
53	Oseltamivir	FAERS: 1	US FAERS
54	Paroxetine	FAERS: 1	US FAERS
55	Raloxifene Hydrochloride	FAERS: 1	US FAERS
56	Rivastigmine	FAERS: 1	US FAERS
57	Sildenafil Citrate	FAERS: 1	US FAERS
58	Sulfasalazine	FAERS: 1	US FAERS
59	Tadalafil	FAERS: 1	US FAERS
60	Thyroxine	FAERS: 1	US FAERS
61	Topiramate	FAERS: 1	US FAERS
62	Valproic Acid	FAERS: 1	US FAERS
63	Valproic Acid	FAERS: 1	US FAERS
64	etonogestrel	FAERS: 1	US FAERS
65	ivacaftor	FAERS: 1	US FAERS
66	montelukast	FAERS: 1	US FAERS
67	palbociclib	FAERS: 1	US FAERS
68	pirfenidone	FAERS: 1	US FAERS
69	suvorexant	FAERS: 1	US FAERS
70	teriflunomide	FAERS: 1	US FAERS
71	tesamorelin	FAERS: 1	US FAERS
72	5-O-[1-[3,3-Diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydron;chloride		OFFSIDES
73	Azithromycin		SIDER
74	Bendamustine Hydrochloride		OFFSIDES
75	Erlotinib Hydrochloride		OFFSIDES
76	Erlotinib Hydrochloride		OFFSIDES
77	Hydroxyzine		OFFSIDES
78	Ofloxacin		SIDER
79	Pyridostigmine Bromide		OFFSIDES
80	Ribavirin		OFFSIDES
81	Sodium gualenate		OFFSIDES
82	alfacalcidol		OFFSIDES
83	brotizolam		OFFSIDES
84	etizolam		OFFSIDES
85	levocabastine		OFFSIDES
86	polaprezinc		OFFSIDES
87	tandospirone		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Borrelia Infections	25.5%
2	Leptospirosis	25.5%
3	Pneumonia, Bacterial	25.4%
4	Lung Diseases, Fungal	24.9%
5	Lung Abscess	24.4%
6	Lyme Disease	23.6%
7	Relapsing Fever	23.6%
8	Rhinoscleroma	23.3%
9	Pleuropneumonia	23%
10	Human Ehrlichiosis	22.5%
11	Pleurisy	22.1%
12	Pneumonia	22.1%
13	Lobar Pneumonia	22.1%
14	Tracheitis	22.1%
15	Pneumonitis	22.1%
16	Bronchitis	21.7%
17	Tuberculosis, Pulmonary	21.5%
18	Brucellosis	21%
19	Campylobacter infection	21%
20	Enterobacteriaceae Infections	21%
21	Pseudomonas Infections	21%
22	Q Fever	21%
23	Vibrio Infections	21%
24	Helicobacter Infections	21%
25	Neisseriaceae Infections	21%
26	Burkholderia Infections	21%
27	Flavobacteriaceae Infections	21%
28	Moraxellaceae Infections	21%
29	Burkholderia cepacia Infection	21%
30	Skin Diseases, Bacterial	20.3%
31	Bacteremia	20.2%
32	Ulcerative stomatitis	20%
33	Japanese Spotted Fever	19.8%
34	Pelvic Infection	19.7%
35	Wound Infection	19.7%
36	Soft Tissue Infection	19.7%
37	Community-Acquired Infections	19.7%
38	Human anaplasmosis	19.4%
39	Lyme Neuroborreliosis	18.8%
40	Erythema Chronicum Migrans	18.7%
41	Laryngitis	18.5%
42	Rhinitis	18.5%
43	Central Nervous System Bacterial Infections	18.3%
44	Syphilis	18.2%
45	Blastomycosis	18.1%
46	Bronchopneumonia	18.1%
47	Gram-Positive Bacterial Infections	17.9%
48	Bacterial Endocarditis	17.6%
49	Sinusitis	16.9%
50	Chlamydia Infections	16.8%
51	Gonorrhea	16.8%
52	Mycoses	16.8%
53	Common Cold	16.3%
54	Influenza	16.3%
55	Catarrh	16.3%
56	Eye Infection	16.3%
57	Severe Acute Respiratory Syndrome	16.2%
58	Hidradenitis Suppurativa	16.1%
59	Bronchitis, Chronic	16.1%
60	Bronchiolitis	16.1%
61	Aspiration Pneumonia	16.1%
62	Mycetoma	16.1%
63	Bone Diseases, Infectious	15.9%
64	Pregnancy Complications, Infectious	15.9%
65	Skin Diseases, Infectious	15.9%
66	Rocky Mountain Spotted Fever	15.8%
67	Arthritis, Infectious	15.6%
68	Suppuration	15.6%
69	Erysipelas	15.6%
70	Staphylococcal Skin Infections	15.6%
71	Cross Infection	15.5%
72	Septicemia	15.5%
73	Sepsis	15.5%
74	Neurosyphilis	15.5%
75	Epiglottitis	15.1%
76	Aspergillosis, Allergic Bronchopulmonary	15%
77	Dermatomycoses	14.7%
78	Erythrasma	14.6%
79	Cellulitis	14.4%
80	Endotoxemia	14.3%
81	Acinetobacter Infections	14.2%
82	Bacteroides Infections	14.2%
83	Cholera	14.2%
84	Escherichia coli Infections	14.2%
85	Haemophilus Infections	14.2%
86	Klebsiella Infections	14.2%
87	Meningococcal Infections	14.2%
88	Mycoplasma Infections	14.2%
89	Pasteurella Infections	14.2%
90	Proteus Infections	14.2%
91	Rickettsia Infections	14.2%
92	Salmonella infections	14.2%
93	Scrub Typhus	14.2%
94	Serratia Infections	14.2%
95	Ureaplasma Infections	14.2%
96	Bacterial Vaginosis	14.1%
97	Opportunistic Infections	13.9%
98	Pharyngitis	13.9%
99	Pneumonia, Viral	13.9%
100	Impetigo	13.8%
101	Retropharyngeal Abscess	13.8%
102	Ecthyma	13.6%
103	Subacute Bacterial Endocarditis	13.6%
104	Central Nervous System Infection	13.5%
105	Pneumonia, Lipid	13.2%
106	Urinary tract infection	13.1%
107	Lymphogranuloma Venereum	12.6%
108	Peritonsillar Abscess	12.2%
109	Fungemia	12.2%
110	Candidiasis, Chronic Mucocutaneous	11.8%
111	Cutaneous Candidiasis	11.8%
112	Tracheobronchomegaly	11.8%
113	Staphylococcal Scalded Skin Syndrome	11.7%
114	Joint Tuberculosis	11.6%
115	Tuberculosis, Osteoarticular	11.6%
116	Bone Tuberculosis	11.6%
117	Sexually Transmitted Diseases	11.6%
118	Hordeolum	11.5%
119	Bacterial conjunctivitis	11.4%
120	Ophthalmia Neonatorum	11.4%
121	Trachoma	11.4%
122	Syphilis, Congenital	11.1%
123	Respiratory Distress Syndrome, Adult	11%
124	Actinomycetales Infections	10.9%
125	Clostridium Infections	10.9%
126	Listeriosis	10.9%
127	Staphylococcal Infections	10.9%
128	Streptococcal Infections	10.9%
129	Bacillaceae Infections	10.9%
130	Clostridium difficile infection	10.9%
131	Psittacosis	10.8%
132	Paratyphoid Fever	10.8%
133	Plague	10.8%
134	Typhoid Fever	10.8%
135	TYPHUS	10.8%
136	Yersinia pseudotuberculosis Infections	10.8%
137	Bubonic Plague	10.8%
138	Asthma	10.7%
139	Candidemia	10.6%
140	Bronchial Diseases	10.6%
141	Lung diseases	10.6%
142	Pleural Diseases	10.6%
143	Respiration Disorders	10.6%
144	Thoracic Diseases	10.6%
145	Tracheal Diseases	10.6%
146	Brain Abscess	10.6%
147	Panophthalmitis	10.4%
148	Furunculosis	10.3%
149	furuncle	10.3%
150	Meningitis, Haemophilus	10.3%
151	Endophthalmitis	10.2%
152	Peritonitis	10.2%
153	Osteomyelitis	10.1%
154	Periostitis	10.1%
155	Surgical Wound Infection	10.1%
156	Tonsillitis	10.1%
157	Abscess	10%
158	Adnexitis	10%
159	Empyema	10%
160	Pelvic Inflammatory Disease	10%
161	Chromoblastomycosis	9.9%
162	Dermatophytosis	9.9%
163	Sporotrichosis	9.9%
164	Tinea	9.9%
165	Tinea Versicolor	9.9%
166	Trichophytosis	9.9%
167	Hyalohyphomycosis	9.9%
168	carbuncle	9.7%
169	Aspergillosis	9.4%
170	Candidiasis	9.4%
171	Coccidioidomycosis	9.4%
172	Granuloma, Laryngeal	9.4%
173	Histoplasmosis	9.4%
174	Paracoccidioidomycosis	9.4%
175	Zygomycosis	9.4%
176	Phaeohyphomycosis	9.4%
177	Pneumocystis Infections	9.4%
178	Invasive Pulmonary Aspergillosis	9.4%
179	Dysentery, Bacillary	9.3%
180	Vocal Cord Dysfunction	9.2%
181	Psoas Abscess	9.2%
182	Abdominal Abscess	9.2%
183	Respiratory Distress Syndrome, Newborn	9.1%
184	Bronchial Fistula	9.1%
185	Erysipelothrix infection	9.1%
186	Lung Neoplasms	9.1%
187	Pleural Neoplasms	9.1%
188	Salmonella Infections, Animal	9%
189	Bacterial Infections	8.8%
190	Laryngeal Diseases	8.8%
191	Nose Diseases	8.8%
192	Pulmonary Aspergillosis	8.7%
193	Bronchopulmonary Aspergillosis	8.7%
194	Salmonella food poisoning	8.6%
195	Superinfection	8.6%
196	Pleural Effusion, Malignant	8.6%
197	Corneal Ulcer	8.5%
198	Meningitis, Listeria	8.4%
199	Granuloma, Respiratory Tract	8.4%
200	Respiratory Hypersensitivity	8.4%
201	Respiratory Tract Fistula	8.4%
202	Puerperal Infection	8.4%
203	Spondylitis	8.4%
204	Appendicitis	8.3%
205	Bacteriuria	8.3%
206	Pyuria	8.3%
207	Pyomyositis	8.3%
208	Endotoxic shock	8.3%
209	Septic Shock	8.3%
210	Toxic Shock Syndrome	8.3%
211	Infection	8%
212	Choanal Atresia	7.9%
213	Laryngocele	7.9%
214	Bronchial Neoplasms	7.8%
215	Neuroaspergillosis	7.8%
216	Tracheal Neoplasms	7.8%
217	Tuberculosis, Spinal	7.7%
218	Erythema Induratum	7.7%
219	Fusariosis	7.7%
220	Otomycosis	7.6%
221	Nasopharyngitis	7.5%
222	Actinomycosis	7.5%
223	Corynebacterium Infections	7.5%
224	Gas Gangrene	7.5%
225	Mycobacterium Infections	7.5%
226	Nocardia Infections	7.5%
227	Pneumococcal Infections	7.5%
228	Scarlet Fever	7.5%
229	Tetanus	7.5%
230	Pulmonary Nocardiosis	7.5%
231	Piedra	7.5%
232	Central Nervous System Fungal Infections	7.5%
233	Meningitis, Pneumococcal	7.5%
234	Idiopathic Pulmonary Fibrosis	7.3%
235	Diverticulitis	7.3%
236	Meningitis, Bacterial	7.2%
237	Arthritis, Reactive	7%
238	Pneumoconiosis	6.9%
239	Laryngeal neoplasm	6.9%
240	Altitude Sickness	6.8%
241	Atelectasis	6.8%
242	Bronchospasm	6.8%
243	Bronchiectasis	6.8%
244	Chylothorax	6.8%
245	Hydropneumothorax	6.8%
246	Hydrothorax	6.8%
247	Pulmonary Hypertension	6.8%
248	Pneumothorax	6.8%
249	Pulmonary Alveolar Proteinosis	6.8%
250	Pulmonary Edema	6.8%
251	Pulmonary Fibrosis	6.8%
252	Respiratory Insufficiency	6.8%
253	Tracheal Stenosis	6.8%
254	Bronchial Hyperreactivity	6.8%
255	Hamman-Rich syndrome	6.8%
256	Lung Diseases, Interstitial	6.8%
257	Respiratory Depression	6.8%
258	Lung Diseases, Obstructive	6.8%
259	Respiratory Failure	6.8%
260	Laryngospasm	6.7%
261	Hyaline Membrane Disease	6.7%
262	Asthma, Exercise-Induced	6.6%
263	Status Asthmaticus	6.6%
264	Multiple Pulmonary Nodules	6.6%
265	Tinea Capitis	6.6%
266	Onychomycosis	6.6%
267	AIDS-Related Opportunistic Infections	6.3%
268	Bronchiolitis Obliterans	6.3%
269	Diverticulum	6.1%
270	Diverticulosis	6.1%
271	Liver Abscess	6.1%
272	Scimitar Syndrome	6.1%
273	Primary Ciliary Dyskinesia	6.1%
274	Discitis	6%
275	Mastoiditis	6%
276	Petrositis	6%
277	Meconium Aspiration Syndrome	6%
278	Paranasal Sinus Neoplasms	6%
279	Acute Chest Syndrome	5.9%
280	Tuberculosis, Meningeal	5.9%
281	Mucormycosis	5.9%
282	Asthma, Occupational	5.9%
283	Diphtheria	5.8%
284	Leprosy	5.8%
285	Mycobacterium Infections, Nontuberculous	5.8%
286	Tuberculosis	5.8%
287	Mycobacterium abscessus Infection	5.8%
288	Radiation Pneumonitis	5.8%
289	Radiation Fibrosis	5.8%
290	Tinea Pedis	5.7%
291	Meningitis, Cryptococcal	5.6%
292	Asbestosis	5.6%
293	Berylliosis	5.6%
294	Silicosis	5.6%
295	Granuloma, Lethal Midline	5.5%
296	Laryngeal Edema	5.5%
297	Nose Deformities, Acquired	5.5%
298	Lung Injury	5.5%
299	Hepatopulmonary Syndrome	5.5%
300	Respiratory Aspiration	5.5%
301	Apnea	5.4%
302	Cheyne-Stokes Respiration	5.4%
303	Dyspnea	5.4%
304	Hemothorax	5.4%
305	Hyperventilation	5.4%
306	Mouth Breathing	5.4%
307	Nose Neoplasms	5.4%
308	Tachypnea	5.4%
309	Pulmonary Embolism	5.4%
310	Pulmonary Eosinophilia	5.4%
311	Eosinophilic Pneumonia	5.4%
312	Laryngopharyngeal Reflux	5.4%
313	Farmer's Lung	5.3%
314	Toxoplasmosis, Cerebral	5.2%
315	Hoarseness	5.2%
316	Epidural Abscess	5.2%
317	Hay fever	5.2%
318	Rhinitis, Allergic, Perennial	5.2%
319	Gram-Negative Bacterial Infections	5.1%
320	Rheumatic Fever	5.1%
321	Airway Obstruction	5%
322	Choking	5%
323	Chronic Obstructive Airway Disease	5%
324	Mediastinitis	5%
325	Middle Lobe Syndrome	5%
326	Acute Lung Injury	5%
327	Asthma, Aspirin-Induced	5%
328	Mycobacterium avium-intracellulare Infection	5%
329	Lymph Node Tuberculosis	5%
330	Tuberculosis, Miliary	5%
331	Tuberculosis, Multidrug-Resistant	5%
332	Leprosy, Multibacillary	5%
333	Latent Tuberculosis	5%
334	Enterocolitis, Pseudomembranous	4.9%
335	pseudomembranous colitis	4.9%
336	Kartagener Syndrome	4.9%
337	Maxillary Sinus Neoplasms	4.9%
338	Waterhouse-Friderichsen Syndrome	4.9%
339	Lemierre Syndrome	4.8%
340	Oral candidiasis	4.8%
341	Rheumatic Heart Disease	4.7%
342	Laryngostenosis	4.6%
343	Nasal Polyps	4.6%
344	Borderline leprosy	4.6%
345	Leprosy, Lepromatous	4.6%
346	Tuberculoid leprosy	4.6%
347	Extensively Drug-Resistant Tuberculosis	4.6%
348	Hemoptysis	4.5%
349	Botulism	4.3%
350	Pulmonary Emphysema	4.2%
351	Mediastinal Cyst	4.1%
352	Pericardial Cyst	4.1%
353	Persistent Fetal Circulation Syndrome	4.1%
354	Thymic Cyst	4.1%
355	Tuberculosis, Gastrointestinal	4%
356	Croup	4%
357	Histiocytosis, Langerhans-Cell	4%
358	Mediastinal Emphysema	4%
359	Rhinitis, Vasomotor	4%
360	Hypoventilation	4%
361	Acidosis, Respiratory	4%
362	Alkalosis, Respiratory	4%
363	Sarcoidosis, Pulmonary	4%
364	Sleep Apnea Syndromes	4%
365	Pulmonary Infarction	4%
366	Cystic Fibrosis	4%
367	Tuberculosis, Central Nervous System	4%
368	Voice Disorders	3.9%
369	Voice Disturbance	3.9%
370	Epistaxis	3.9%
371	Meningitis, Fungal	3.9%
372	Candidiasis, Vulvovaginal	3.8%
373	Respiratory Tract Infections	3.5%
374	Laryngomalacia	3.4%
375	Vocal Cord Paralysis	3.4%
376	Pertussis	3.4%
377	Bordetella Infections	3.4%
378	Liver Abscess, Amebic	3.4%
379	Bronchopulmonary Dysplasia	3.3%
380	Dyspnea, Paroxysmal	3.3%
381	Respiratory Paralysis	3.3%
382	Granulomatosis with polyangiitis	3.3%
383	Sleep Apnea, Obstructive	3.3%
384	Sleep Apnea, Central	3.3%
385	Aphonia	2.9%
386	Dysphonia	2.9%
387	Anti-Glomerular Basement Membrane Disease	2.9%
388	Bronchomalacia	2.8%
389	Tracheomalacia	2.8%
390	Transfusion-Related Acute Lung Injury	2.8%
391	Tuberculosis, Renal	2.3%
392	Eosinophilic Granuloma	2.1%

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