MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Myoglobinuria

(UMLS:C0027080)

Definition:: The presence of MYOGLOBIN in URINE usually as a result of rhabdomyolysis.
UMLS ID:: C0027080
MeSH ID:: D009212

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.651.807.628

Synonym(s)

Myoglobinuria

MYOGLOBINURIA

Urine myoglobin increased

myoglobinuria

myoglobulinuria

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Prednisolone	FAERS: 15		US FAERS
2	Zoledronic Acid	FAERS: 7		US FAERS
3	Rosuvastatin Calcium	FAERS: 5 Canada Vigilance: 2		Canada Vigilance US FAERS
4	Valproic Acid	FAERS: 5		US FAERS
5	Valsartan	FAERS: 5		US FAERS
6	Atorvastatin	FAERS: 4		US FAERS
7	Simvastatin	FAERS: 4	18819764 19099134	CTD US FAERS
8	Acetaminophen	FAERS: 3		US FAERS
9	Atorvastatin	FAERS: 3		SIDER US FAERS
10	Ciprofloxacin	FAERS: 3		US FAERS
11	Propofol	FAERS: 3		US FAERS
12	Tamsulosin	FAERS: 3		US FAERS
13	Valproic Acid	FAERS: 3		US FAERS
14	Clozapine	FAERS: 2	10085753	CTD US FAERS
15	Diclofenac	FAERS: 2	8701974	CTD US FAERS
16	Imatinib Mesylate	FAERS: 2		US FAERS
17	Levetiracetam	FAERS: 2		US FAERS
18	Lorazepam	FAERS: 2 Canada Vigilance: 2		Canada Vigilance US FAERS
19	Olanzapine	FAERS: 2 Canada Vigilance: 1	10085753	CTD Canada Vigilance US FAERS
20	Tamsulosin	FAERS: 2		US FAERS
21	silodosin	FAERS: 2		US FAERS
22	Bortezomib	FAERS: 1		US FAERS
23	Cefdinir	FAERS: 1		US FAERS
24	Chlorpromazine	FAERS: 1		US FAERS
25	Crizotinib	FAERS: 1		US FAERS
26	Fluconazole	FAERS: 1		US FAERS
27	Lovastatin	FAERS: 1	3076126 8360706	CTD US FAERS
28	Methylphenidate	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
29	Moxifloxacin	FAERS: 1		US FAERS
30	Naltrexone	FAERS: 1		US FAERS
31	Paroxetine	FAERS: 1		US FAERS
32	Potassium Chloride	FAERS: 1		US FAERS
33	Pregabalin	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
34	Ritodrine	FAERS: 1		US FAERS
35	Rosuvastatin Calcium	FAERS: 1		SIDER US FAERS
36	Sertraline	FAERS: 1		US FAERS
37	Telbivudine	FAERS: 1		US FAERS
38	Triazolam	FAERS: 1		US FAERS
39	Valproic Acid	FAERS: 1		US FAERS
40	fexofenadine	FAERS: 1		US FAERS
41	gemcitabine	FAERS: 1		US FAERS
42	Aminocaproic Acid		6612533 7086489	CTD
43	Amoxapine		6870433	CTD
44	Amphetamine		3057269 7058372	CTD
45	Bezafibrate		1291164 3374444	CTD
46	Calcitriol		10362817	CTD
47	Clofibrate		846520	CTD
48	Colchicine		1499522	CTD
49	Enflurane		731274 8865732	CTD
50	Fluvastatin			SIDER
51	Glycerol		10362817	CTD
52	Haloperidol		6121542	CTD
53	Halothane		7284224	CTD
54	Loxapine		7258388	CTD
55	Methadone		4936579	CTD
56	Methamphetamine		848798	CTD
57	Penicillins			SIDER
58	Pentamidine		3878136	CTD
59	Perphenazine		3588517	CTD
60	Phenmetrazine		848798	CTD
61	Pravastatin			SIDER
62	Prednisone		3288755	CTD
63	Promethazine		10548178	CTD
64	Pyrazinamide		1803050	CTD
65	Risperidone			SIDER
66	Succinylcholine		View details 731274 6744092 7284224 8051650 8865732	CTD SIDER
67	Theophylline		8865732	CTD
68	WR 242511		18821488	CTD
69	benzathine			SIDER
70	cerivastatin	Canada Vigilance: 1		Canada Vigilance
71	cerivastatin			SIDER
72	liposomal amphotericin B		5536569	CTD
73	pitavastatin			SIDER
74	ziprasidone			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Myofascial Pain Syndromes	31%
2	Contracture	27.9%
3	Compartment syndromes	20.9%
4	Tendinitis	20.9%
5	Tendinopathy	20.9%
6	Arthrogryposis	20.8%
7	Fibromyalgia	20.7%
8	Polymyalgia Rheumatica	20.7%
9	Myositis	20.5%
10	Isaacs syndrome	20.5%
11	Myotonic Disorders	20.5%
12	Fibrodysplasia Ossificans Progressiva	20%
13	Myositis Ossificans	20%
14	Tenosynovitis	20%
15	Ischemic contracture	18.7%
16	Bone Diseases	18.5%
17	Fasciitis	18.5%
18	Foot Deformities	18.5%
19	Arthropathy	18.5%
20	Hip Contracture	17.8%
21	Medial Tibial Stress Syndrome	15.5%
22	Mitochondrial Myopathies	15.3%
23	Muscle Cramp	15.1%
24	Eosinophilia-Myalgia Syndrome	15.1%
25	Muscle Rigidity	14.9%
26	Muscle Spasticity	14.9%
27	Cogwheel Rigidity	14.9%
28	Nuchal Rigidity	14.9%
29	Osteoarthropathy, Secondary Hypertrophic	14%
30	Fasciitis, Plantar	14%
31	Anterior Compartment Syndrome	13.3%
32	Enthesopathy	13.3%
33	Abdominal Compartment Syndrome	13.3%
34	Polymyositis	13.2%
35	Temporomandibular Joint Dysfunction Syndrome	13%
36	Chronic Fatigue Syndrome	12.9%
37	Jaw Diseases	12.8%
38	Muscle Weakness	12.2%
39	Cartilage Diseases	12.2%
40	Foot Diseases	12.2%
41	Rheumatism	12.2%
42	Chondromalacia	12.2%
43	Musculoskeletal Pain	12.1%
44	Temporomandibular Joint Disorders	12.1%
45	Familial Periodic Paralysis	12%
46	Arthritis	10.3%
47	Bone Diseases, Developmental	10.3%
48	Bursitis	10.3%
49	Hyperostosis	10.3%
50	Joint Instability	10.3%
51	Osteitis	10.3%
52	Osteitis Deformans	10.3%
53	Osteochondritis	10.3%
54	Osteochondrosis	10.3%
55	Spinal Diseases	10.3%
56	Synovitis	10.3%
57	Joint laxity	10.3%
58	Polyarthritis	10.3%
59	Frozen shoulder	10.3%
60	Patellofemoral Pain Syndrome	10.3%
61	Metatarsalgia	10.3%
62	Muscular Dystrophy	10.1%
63	Orbital Myositis	10.1%
64	Dupuytren Contracture	10%
65	Myalgia	9.9%
66	Pyomyositis	9.9%
67	Pectus carinatum	9.1%
68	Periarthritis	8.9%
69	Myotonic Dystrophy	8.6%
70	Pectus excavatum	8.5%
71	Rheumatic Fever	8.4%
72	Osteoarthritis, Spine	8.1%
73	Myotonia Congenita	7.9%
74	Platybasia	7.9%
75	Hypokalemic periodic paralysis	7.8%
76	Gout	7.8%
77	Osteoarthritis, Knee	7.7%
78	Klippel-Feil Syndrome	7.6%
79	Synostosis	7.6%
80	Welander Distal Myopathy	7.3%
81	Bone Diseases, Endocrine	7.3%
82	Ankylosing spondylitis	7.1%
83	Bone Diseases, Infectious	7%
84	Bone neoplasms	7%
85	Maxillary Diseases	7%
86	Osteopenia	7%
87	Talipes	6.9%
88	Rheumatoid Arthritis	6.8%
89	Juvenile arthritis	6.8%
90	Bone Resorption	6.8%
91	Hemarthrosis	6.8%
92	Tietze's Syndrome	6.8%
93	Limb Deformities, Congenital	6.8%
94	Craniofacial Abnormalities	6.8%
95	Aseptic Necrosis of Bone	6.8%
96	Ainhum	6.7%
97	Bunion	6.7%
98	Dysostoses	6.7%
99	Gigantism	6.7%
100	Spinal Neoplasms	6.7%
101	Spinal Stenosis	6.7%
102	Spondylitis	6.7%
103	Spondylosis	6.7%
104	Intervertebral Disc Degeneration	6.7%
105	Sacroiliitis	6.7%
106	Mitochondrial Encephalomyopathies	6.6%
107	Dermatomyositis	6.1%
108	Spondylarthropathies	5.9%
109	Muscular Dystrophy, Duchenne	5.9%
110	Craniofacial Dysostosis	5.7%
111	Rheumatoid Nodule	5.7%
112	Craniosynostosis	5.7%
113	Syndactyly	5.7%
114	Brachycephaly	5.7%
115	Arthritis, Psoriatic	5.7%
116	Arthritis, Gouty	5.4%
117	Congenital clubfoot	5.3%
118	Vertical Talus	5.3%
119	Gastroschisis	5%
120	Arthritis, Reactive	5%
121	Chondrodysplasia Punctata	4.9%
122	Enchondromatosis	4.9%
123	Lordosis	4.9%
124	Osteosclerosis	4.9%
125	Spondylolysis	4.9%
126	kyphosis	4.9%
127	Kashin-Beck Disease	4.9%
128	Discitis	4.9%
129	Acrocephalosyndactylia	4.8%
130	Felty Syndrome	4.6%
131	Arthritis, Infectious	4.5%
132	Multiple Epiphyseal Dysplasia	4.5%
133	Osteochondrodysplasias	4.5%
134	Osteomyelitis	4.4%
135	Osteoporosis	4.4%
136	Periostitis	4.4%
137	Bone Demineralization, Pathologic	4.4%
138	Post-Traumatic Osteoporosis	4.4%
139	Arthritis, Experimental	4.4%
140	Poland Syndrome	4.4%
141	Alveolar Bone Loss	4.4%
142	Amelia	4.4%
143	Arachnodactyly	4.4%
144	Ectromelia	4.4%
145	Femur Head Necrosis	4.4%
146	Hemimelia	4.4%
147	Phocomelia	4.4%
148	Sirenomelia	4.4%
149	Polydactyly	4.4%
150	Brachydactyly	4.4%
151	Plagiocephaly	4.4%
152	Lower Extremity Deformities, Congenital	4.4%
153	Upper Extremity Deformities, Congenital	4.4%
154	Osteolysis	4.4%
155	Jaw Abnormalities	4.3%
156	Nail-Patella Syndrome	4.1%
157	Giant Cell Epulis	4.1%
158	Melorheostosis	4.1%
159	Osteopetrosis	4.1%
160	Spondylolisthesis	4.1%
161	Arthralgia	4%
162	Polyarthralgia	4%
163	Congenital Hypothyroidism	3.9%
164	Tuberculosis, Spinal	3.9%
165	Rheumatoid Vasculitis	3.8%
166	Prognathism	3.8%
167	Goldenhar Syndrome	3.8%
168	Dwarfism	3.6%
169	Mandibulofacial Dysostosis	3.6%
170	Antley-Bixler Syndrome Phenotype	3.5%
171	Hip Dislocation	3.4%
172	Shoulder Dislocation	3.4%
173	Laryngomalacia	3.4%
174	Hip Dysplasia	3.4%
175	Eosinophilic Granuloma	3.3%
176	Sicca Syndrome	3.3%
177	Sjogren's Syndrome	3.3%
178	Acromegaly	3.3%
179	Joint Tuberculosis	3.3%
180	Tuberculosis, Osteoarticular	3.3%
181	Bone Tuberculosis	3.3%
182	Osteoporosis, Postmenopausal	3.3%
183	Palatal Neoplasms	3%
184	Micrognathism	3%
185	Pierre Robin Syndrome	3%
186	MELAS Syndrome	2.9%
187	Rubinstein-Taybi Syndrome	2.9%
188	Maxillofacial Abnormalities	2.7%
189	Retrognathia	2.6%
190	Kearns-Sayre syndrome	2.6%
191	Rickets	2.6%
192	Bronchomalacia	2.6%
193	Tracheomalacia	2.6%
194	Microcephaly	2.6%
195	Macrocephaly	2.6%
196	Shoulder Pain	2.6%
197	Osteogenesis Imperfecta	2.5%
198	Mastoiditis	2.4%
199	Petrositis	2.4%
200	Basal Cell Nevus Syndrome	2.3%
201	Pseudohypoparathyroidism	2.2%
202	Cleft Palate	2.1%
203	Osteomalacia	1.9%
204	Porencephaly	1.9%
205	Noonan Syndrome	1.9%
206	Marfan Syndrome	1.7%
207	Holoprosencephaly	1.7%
208	Cockayne Syndrome	1.4%
209	Radicular Cyst	1.3%
210	Nose Neoplasms	1.3%
211	Renal Osteodystrophy	1.2%
212	Renal rickets	1.2%
213	Familial Hypophosphatemic Rickets	0.6%

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