MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sarcoidosis, Pulmonary

(UMLS:C0036205)

Definition:: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)
UMLS ID:: C0036205
MeSH ID:: D017565

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.381.483.725

Classification 2:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.604.515.827.725

Synonym(s)

Sarcoidosis, Pulmonary

Lung Sarcoidosis

Pulmonary Sarcoidosis

Pulmonary sarcoidosis

SARCOIDOSIS PULMONARY

Sarcoidosis of lung

disease (or disorder); lung, in sarcoidosis

lung sarcoid

lung sarcoidosis

10.

lung; disease, in sarcoidosis

11.

lung; sarcoidosis

12.

lungs sarcoidosis

13.

pulmonary sarcoidosis

14.

sarcoidosis lung

15.

sarcoidosis pulmonary

16.

sarcoidosis with lung involvement

17.

sarcoidosis; lung

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ribavirin		15316444	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Histiocytosis, Langerhans-Cell	30.6%
2	Pneumoconiosis	27.6%
3	Idiopathic Pulmonary Fibrosis	27%
4	Radiation Pneumonitis	22.2%
5	Radiation Fibrosis	22.2%
6	Pneumonia	20.5%
7	Lobar Pneumonia	20.5%
8	Respiratory Distress Syndrome, Adult	20.5%
9	Pneumonitis	20.5%
10	Atelectasis	20.2%
11	Pulmonary Hypertension	20.2%
12	Pulmonary Alveolar Proteinosis	20.2%
13	Pulmonary Edema	20.2%
14	Pulmonary Fibrosis	20.2%
15	Hamman-Rich syndrome	20.2%
16	Lung Diseases, Obstructive	20.2%
17	Asbestosis	19.9%
18	Berylliosis	19.9%
19	Silicosis	19.9%
20	Granulomatosis with polyangiitis	18.4%
21	Granuloma	17.6%
22	Tumor Lysis Syndrome	17.4%
23	Adenitis	16.9%
24	Histiocytosis	16.9%
25	Lymphadenitis	16.9%
26	Lymphangitis	16.9%
27	Lymphedema	16.9%
28	Splenic Diseases	16.9%
29	Thymus Hyperplasia	16.9%
30	Pseudolymphoma	16.9%
31	Lymphadenopathy	16.9%
32	Lung Diseases, Fungal	16.6%
33	Bronchitis	16.3%
34	Respiratory Distress Syndrome, Newborn	16.3%
35	Lung Abscess	16.2%
36	Lung Neoplasms	16.2%
37	Pulmonary Eosinophilia	16.2%
38	Eosinophilic Pneumonia	16.2%
39	Tuberculosis, Pulmonary	16.1%
40	Agammaglobulinemia	16.1%
41	Lung Injury	15.4%
42	Hepatopulmonary Syndrome	15.4%
43	Anti-Glomerular Basement Membrane Disease	15.4%
44	Heavy Chain Disease	15.1%
45	Pulmonary Embolism	15%
46	Bronchopneumonia	14.8%
47	Bronchitis, Chronic	14.2%
48	Lymphoma	14.1%
49	Farmer's Lung	13.8%
50	Eosinophilic Granuloma	13.7%
51	Asthma	13.5%
52	Sezary Syndrome	13.3%
53	Pleuropneumonia	13.3%
54	Aspiration Pneumonia	13.2%
55	Infectious Mononucleosis	13.2%
56	Chronic Obstructive Airway Disease	13.2%
57	Middle Lobe Syndrome	13.2%
58	Acute Lung Injury	13.2%
59	Lymphocele	12.8%
60	Lymphatic Abnormalities	12.8%
61	Thymus Neoplasms	12.6%
62	Hemoptysis	12.1%
63	Lymphangiectasis, Intestinal	11.9%
64	Autoimmune Lymphoproliferative Syndrome	11.9%
65	Bronchial Diseases	11.8%
66	Pleural Diseases	11.8%
67	Respiration Disorders	11.8%
68	Thoracic Diseases	11.8%
69	Tracheal Diseases	11.8%
70	Acute Chest Syndrome	11.3%
71	Bronchiolitis	11.2%
72	Pneumonia, Viral	11%
73	Pneumonia, Bacterial	10.7%
74	Hyaline Membrane Disease	10.5%
75	Multiple Pulmonary Nodules	10.5%
76	Cystic Fibrosis	10.4%
77	Waldenstrom Macroglobulinemia	10.3%
78	Tracheobronchomegaly	10.3%
79	Pleurisy	10.3%
80	Tracheitis	10.3%
81	Scimitar Syndrome	10.2%
82	Persistent Fetal Circulation Syndrome	10.1%
83	Mucocutaneous Lymph Node Syndrome	10.1%
84	Pulmonary Aspergillosis	9.9%
85	Bronchopulmonary Aspergillosis	9.9%
86	Elephantiasis	9.9%
87	Hypersplenism	9.9%
88	Elephantiasis Nostras Verrucosa	9.9%
89	Pulmonary Infarction	9.8%
90	Pulmonary Emphysema	9.8%
91	Pneumonia, Lipid	9.8%
92	Laryngeal Diseases	9.2%
93	Nose Diseases	9.2%
94	Hodgkin Disease	9.2%
95	Lymphoma, Non-Hodgkin	9.2%
96	Leukemia, T-Cell	9.1%
97	Leukemia, B-Cell	9.1%
98	Aspergillosis, Allergic Bronchopulmonary	9%
99	Respiratory Tract Infections	8.8%
100	Meconium Aspiration Syndrome	8.8%
101	Granuloma, Respiratory Tract	8.7%
102	Respiratory Hypersensitivity	8.7%
103	Respiratory Tract Fistula	8.7%
104	Bronchiolitis Obliterans	8.5%
105	Laryngitis	8.3%
106	Rhinitis	8.3%
107	Vocal Cord Dysfunction	8.3%
108	Bronchial Fistula	8.1%
109	Pleural Neoplasms	8.1%
110	Transfusion-Related Acute Lung Injury	8%
111	Granuloma, Laryngeal	7.8%
112	Composite Lymphoma	7.7%
113	Lymphangioleiomyomatosis	7.6%
114	Histiocytic Disorders, Malignant	7.6%
115	Splenic Infarction	7.6%
116	Splenic Neoplasms	7.6%
117	Bronchopulmonary Dysplasia	7.4%
118	Choanal Atresia	6.9%
119	Laryngocele	6.9%
120	Lymphoma, Follicular	6.8%
121	T-Cell Lymphoma	6.8%
122	Mantle cell lymphoma	6.8%
123	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	6.8%
124	Leukemia, Large Granular Lymphocytic	6.8%
125	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	6.8%
126	Altitude Sickness	6.7%
127	Bronchospasm	6.7%
128	Bronchiectasis	6.7%
129	Chylothorax	6.7%
130	Hydropneumothorax	6.7%
131	Hydrothorax	6.7%
132	Pneumothorax	6.7%
133	Respiratory Insufficiency	6.7%
134	Tracheal Neoplasms	6.7%
135	Tracheal Stenosis	6.7%
136	Bronchial Hyperreactivity	6.7%
137	Respiratory Depression	6.7%
138	Respiratory Failure	6.7%
139	Sinusitis	6.7%
140	Bronchial Neoplasms	6.6%
141	Blastomycosis	6.6%
142	Pleural Effusion, Malignant	6.6%
143	Lymphohistiocytosis, Hemophagocytic	6.5%
144	Erdheim-Chester Disease	6.5%
145	Splenic Rupture	6.1%
146	Disseminated Intravascular Coagulation	6%
147	Protein S Deficiency	6%
148	Thymoma	5.9%
149	Laryngeal neoplasm	5.9%
150	Invasive Pulmonary Aspergillosis	5.9%
151	Primary Ciliary Dyskinesia	5.9%
152	Anemia	5.6%
153	Blood Coagulation Disorders	5.6%
154	Blood Platelet Disorders	5.6%
155	Bone Marrow Diseases	5.6%
156	Hemorrhagic Disorders	5.6%
157	Leukocyte Disorders	5.6%
158	Methemoglobinemia	5.6%
159	Pancytopenia	5.6%
160	Polycythemia	5.6%
161	Sulfhemoglobinemia	5.6%
162	Thrombophilia	5.6%
163	Erythrocytosis	5.6%
164	Lymphoma, T-Cell, Cutaneous	5.6%
165	Lymphoma, AIDS-Related	5.6%
166	Enteropathy-Associated T-Cell Lymphoma	5.6%
167	Primary Effusion Lymphoma	5.6%
168	Laryngospasm	5.3%
169	Asthma, Exercise-Induced	5.2%
170	Status Asthmaticus	5.2%
171	Thrombocythemia, Essential	5.2%
172	Granuloma, Lethal Midline	5.1%
173	Laryngeal Edema	5.1%
174	Nose Deformities, Acquired	5.1%
175	Respiratory Aspiration	5.1%
176	Apnea	5%
177	Cheyne-Stokes Respiration	5%
178	Common Cold	5%
179	Dyspnea	5%
180	Hemothorax	5%
181	Hyperventilation	5%
182	Influenza	5%
183	Mouth Breathing	5%
184	Tachypnea	5%
185	Catarrh	5%
186	Mycosis Fungoides	5%
187	Lymphomatoid Papulosis	5%
188	Plasmablastic lymphoma	5%
189	Severe Acute Respiratory Syndrome	5%
190	Laryngopharyngeal Reflux	5%
191	Malignant histiocytosis	4.9%
192	Histiocytic sarcoma	4.9%
193	Lymphomatoid Granulomatosis	4.8%
194	Asthma, Occupational	4.5%
195	Nose Neoplasms	4.5%
196	Rhinoscleroma	4.5%
197	Transfusion Reaction	4.4%
198	Hypotensive Transfusion Reaction	4.4%
199	Paranasal Sinus Neoplasms	4.4%
200	Airway Obstruction	4.4%
201	Choking	4.4%
202	Epiglottitis	4.4%
203	Mediastinitis	4.4%
204	Thrombasthenia	4.4%
205	Antithrombin III Deficiency	4.4%
206	Protein C Deficiency	4.4%
207	Pregnancy Complications, Hematologic	4.3%
208	Hematologic Neoplasms	4.3%
209	Hoarseness	4.2%
210	Pharyngitis	4.1%
211	Thrombocytosis	4.1%
212	Laryngostenosis	4.1%
213	Nasal Polyps	4.1%
214	Burkitt Lymphoma	4%
215	Pertussis	4%
216	Bone Marrow Neoplasms	4%
217	Splenosis	3.9%
218	Vitamin K Deficiency	3.9%
219	Afibrinogenemia	3.8%
220	Factor VII Deficiency	3.8%
221	Factor X Deficiency	3.8%
222	Factor XII Deficiency	3.8%
223	Hemophilia A	3.8%
224	Activated Protein C Resistance	3.8%
225	Factor II deficiency	3.8%
226	Factor VIII Deficiency	3.8%
227	Factor V deficiency	3.8%
228	Factor XI Deficiency	3.8%
229	Hypoprothrombinemias	3.8%
230	Kartagener Syndrome	3.8%
231	Hay fever	3.8%
232	Rhinitis, Allergic, Perennial	3.8%
233	Asthma, Aspirin-Induced	3.8%
234	Voice Disorders	3.4%
235	Voice Disturbance	3.4%
236	Epistaxis	3.4%
237	Mediastinal Cyst	3.4%
238	Pericardial Cyst	3.4%
239	Thymic Cyst	3.4%
240	Croup	3.3%
241	Mediastinal Emphysema	3.3%
242	Rhinitis, Vasomotor	3.3%
243	Hypoventilation	3.3%
244	Anemia, Hemolytic	3.3%
245	Anemia, Macrocytic	3.3%
246	Eosinophilia	3.3%
247	Hypoproteinemia	3.3%
248	Leukopenia	3.3%
249	Thrombocytopenia	3.3%
250	Leukostasis	3.3%
251	MYELODYSPLASTIC SYNDROME	3.3%
252	Acidosis, Respiratory	3.3%
253	Alkalosis, Respiratory	3.3%
254	Sleep Apnea Syndromes	3.3%
255	Hemoglobinuria, Paroxysmal	3.3%
256	Leukemoid Reaction	3.3%
257	Polycythemia Vera	3.2%
258	Maxillary Sinus Neoplasms	3.2%
259	Laryngomalacia	2.9%
260	Vocal Cord Paralysis	2.9%
261	Anemia, Diamond-Blackfan	2.7%
262	Wiskott-Aldrich Syndrome	2.7%
263	Tonsillitis	2.6%
264	Purpura, Thrombotic Thrombocytopenic	2.6%
265	Dyspnea, Paroxysmal	2.6%
266	Respiratory Paralysis	2.6%
267	Anemia, Neonatal	2.5%
268	Leukocytosis	2.5%
269	Paraproteinemias	2.5%
270	Pelger-Huet Anomaly	2.5%
271	Pleocytosis	2.5%
272	Anemia, Sickle Cell	2.5%
273	Thalassemia	2.5%
274	Sleep Apnea, Obstructive	2.4%
275	Sleep Apnea, Central	2.4%
276	Aphonia	2.2%
277	Retropharyngeal Abscess	2.2%
278	Dysphonia	2.2%
279	Cryoglobulinemia	2.2%
280	Monoclonal Gammopathy of Undetermined Significance	2.2%
281	Bronchomalacia	2.2%
282	Tracheomalacia	2.2%
283	Primary Myelofibrosis	2.2%
284	Agranulocytosis	2.2%
285	Anemia, Megaloblastic	2.2%
286	Lymphocytosis	2.2%
287	Myelofibrosis	2.2%
288	Myeloid Metaplasia	2.2%
289	Hypoalbuminemia	2.2%
290	Hypereosinophilic syndrome	2.2%
291	bone marrow fibrosis	2.2%
292	Thrombotic Microangiopathies	2.2%
293	Autoimmune thrombocytopenia	2.1%
294	Immune thrombocytopenic purpura	2.1%
295	Hypergammaglobulinemia	2%
296	Ecchymosis	2%
297	Petechiae	2%
298	Purpura	2%
299	Nasopharyngitis	1.9%
300	Hemolytic-Uremic Syndrome	1.9%
301	Purpura, Hyperglobulinemic	1.9%
302	Sickle Cell Trait	1.7%
303	Thrombocytopenic purpura	1.7%
304	Lymphopenia	1.7%
305	Hydrops Fetalis	1.6%
306	Multiple Myeloma	1.6%
307	Job Syndrome	1.6%
308	Fanconi Anemia	1.6%
309	Leukemia, Myelomonocytic, Chronic	1.6%
310	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	1.6%
311	Neutropenia	1.6%
312	Peritonsillar Abscess	1.6%
313	Waterhouse-Friderichsen Syndrome	1.5%
314	Atypical Hemolytic Uremic Syndrome	1.5%
315	Febrile Neutropenia	1.3%
316	Eosinophilia-Myalgia Syndrome	1.3%
317	Chronic granulomatous disease	1.3%
318	Shwartzman Phenomenon	1.3%
319	Hemangioma, Cavernous	1.3%
320	Scurvy	1.3%
321	Purpura Fulminans	1.3%
322	Kernicterus	1.3%
323	Leukemia, Myeloid, Chronic-Phase	1.2%
324	Anemia, Pernicious	1.2%
325	Niemann-Pick Disease, Type C	1.2%
326	POEMS Syndrome	1.1%
327	Pseudoxanthoma Elasticum	0.7%

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