MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Ankylosing spondylitis

(UMLS:C0038013)

Definition:: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.
UMLS ID:: C0038013
MeSH ID:: D013167

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.900.853.625.800.850|C05.550.069.680|C05.550.114.865.800.850

Synonym(s)

Ankylosing spondylitis

ANKYLOSING SPONDYLITIS

AS - Ankylosing spondylitis

Ankylosing Spondylitis

Ankylosing polyarthritis

Ankylosing spondylitis, NOS

Bechterew

Bekhterev's disease

Bekhterev-Strumpell-Marie syndrome

10.

Disease;Bechterews

11.

Idiopathic ankylosing spondylitis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Isotretinoin	FAERS: 40	US FAERS
2	Pregabalin	FAERS: 11	US FAERS
3	Fingolimod Hydrochloride	FAERS: 7	US FAERS
4	Letrozole	FAERS: 7	US FAERS
5	Teriparatide	FAERS: 7 Canada Vigilance: 1	Canada Vigilance US FAERS
6	rofecoxib	FAERS: 7	OFFSIDES US FAERS
7	Celecoxib	FAERS: 6 Canada Vigilance: 1	Canada Vigilance US FAERS
8	tofacitinib	FAERS: 6	US FAERS
9	Diclofenac	FAERS: 5	US FAERS
10	Norgestrel	FAERS: 5 Canada Vigilance: 1	Canada Vigilance US FAERS
11	Atorvastatin	FAERS: 4	US FAERS
12	Methylprednisolone	FAERS: 4	US FAERS
13	Zoledronic Acid	FAERS: 4	US FAERS
14	apremilast	FAERS: 4	US FAERS
15	Clozapine	FAERS: 3 Canada Vigilance: 3	Canada Vigilance OFFSIDES US FAERS
16	NuvaRing	FAERS: 3	US FAERS
17	Sulfasalazine	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
18	Budesonide	FAERS: 2	US FAERS
19	Imatinib Mesylate	FAERS: 2	US FAERS
20	Methotrexate	FAERS: 2	US FAERS
21	Methylphenidate	FAERS: 2	US FAERS
22	Pamidronate	FAERS: 2	US FAERS
23	Quetiapine Fumarate	FAERS: 2	US FAERS
24	rucaparib	FAERS: 2	US FAERS
25	Amlodipine	FAERS: 1	US FAERS
26	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 1	US FAERS
27	Ciprofloxacin	FAERS: 1	US FAERS
28	Cyclosporine	FAERS: 1	US FAERS
29	Dimethyl Fumarate	FAERS: 1	US FAERS
30	Diovan Hct	FAERS: 1	US FAERS
31	Esomeprazole	FAERS: 1	US FAERS
32	Finasteride	FAERS: 1	US FAERS
33	Ibuprofen	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
34	Latanoprost	FAERS: 1	US FAERS
35	Meloxicam	FAERS: 1	SIDER US FAERS
36	Methotrexate	FAERS: 1 Canada Vigilance: 1	Canada Vigilance OFFSIDES US FAERS
37	Naproxen	FAERS: 1	US FAERS
38	Orlistat	FAERS: 1	US FAERS
39	Ortho Evra	FAERS: 1	US FAERS
40	Pentostatin	FAERS: 1	US FAERS
41	Rosuvastatin Calcium	FAERS: 1	US FAERS
42	Testosterone	FAERS: 1	US FAERS
43	Thyroxine	FAERS: 1	US FAERS
44	Warfarin	FAERS: 1	US FAERS
45	ambrisentan	FAERS: 1	US FAERS
46	apixaban	FAERS: 1	US FAERS
47	desloratadine	FAERS: 1	US FAERS
48	exemestane	FAERS: 1	US FAERS
49	niraparib	FAERS: 1	US FAERS
50	teriflunomide	FAERS: 1	US FAERS
51	Acetaminophen	Canada Vigilance: 1	Canada Vigilance
52	Adapalene		OFFSIDES
53	Beclomethasone		OFFSIDES
54	Beclomethasone		OFFSIDES
55	Benzoyl Peroxide		OFFSIDES
56	Cefuroxime		OFFSIDES
57	Cortisone		OFFSIDES
58	Deamino Arginine Vasopressin		OFFSIDES
59	Desogestrel		OFFSIDES
60	Dimenhydrinate		OFFSIDES
61	Dimethindene		OFFSIDES
62	Etoricoxib		OFFSIDES
63	Indomethacin		SIDER
64	Lactulose		OFFSIDES
65	Liraglutide	Canada Vigilance: 1	Canada Vigilance
66	Lisinopril		OFFSIDES
67	Loratadine		OFFSIDES
68	Methyltestosterone		OFFSIDES
69	Naltrexone		OFFSIDES
70	Nelfinavir		OFFSIDES
71	Nevirapine		OFFSIDES
72	Pirenzepine		OFFSIDES
73	Piroxicam		OFFSIDES
74	Pravastatin		OFFSIDES
75	Prednisone acetate		OFFSIDES
76	Ribavirin		OFFSIDES
77	Sumatriptan		OFFSIDES
78	Terazosin		OFFSIDES
79	Tramadol		OFFSIDES
80	Tretinoin		OFFSIDES
81	Trimetazidine		OFFSIDES
82	alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination		OFFSIDES
83	benfluorex		OFFSIDES
84	etravirine		OFFSIDES
85	tetrazepam		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Arthritis, Psoriatic	48.5%
2	Arthritis, Reactive	43.4%
3	Osteoarthritis, Spine	41.1%
4	Osteoarthropathy, Secondary Hypertrophic	39.5%
5	Periarthritis	34.9%
6	Contracture	33.8%
7	Arthrogryposis	31.5%
8	Bursitis	29.5%
9	Joint Instability	29.5%
10	Synovitis	29.5%
11	Joint laxity	29.5%
12	Frozen shoulder	29.5%
13	Patellofemoral Pain Syndrome	29.5%
14	Gout	28.1%
15	Metatarsalgia	28%
16	Sacroiliitis	25.8%
17	Rheumatic Fever	25.5%
18	Hemarthrosis	23.6%
19	Fasciitis	22.8%
20	Foot Deformities	22.8%
21	Rheumatoid Arthritis	22.2%
22	Juvenile arthritis	22.2%
23	Osteochondritis	21.2%
24	Temporomandibular Joint Disorders	21.2%
25	Arthritis, Infectious	21%
26	Arthritis, Experimental	20.7%
27	Platybasia	20.7%
28	Hip Contracture	19.9%
29	Fasciitis, Plantar	19.8%
30	Spinal Neoplasms	19.4%
31	Bone Diseases, Developmental	19.2%
32	Hyperostosis	19.2%
33	Osteitis	19.2%
34	Osteitis Deformans	19.2%
35	Osteochondrosis	19.2%
36	Osteoarthritis, Knee	19.1%
37	Jaw Diseases	18.9%
38	Cartilage Diseases	18.4%
39	Foot Diseases	18.4%
40	Myopathy	18.4%
41	Rheumatism	18.4%
42	Chondromalacia	18.4%
43	Ischemic contracture	18.4%
44	Arthritis	18.4%
45	Polyarthritis	18.4%
46	Spinal Stenosis	18.1%
47	Spondylosis	18.1%
48	Intervertebral Disc Degeneration	18.1%
49	Pectus carinatum	17.9%
50	Arthritis, Gouty	17.8%
51	Nail-Patella Syndrome	17.1%
52	Discitis	16.9%
53	Arthralgia	16.7%
54	Polyarthralgia	16.7%
55	Fibromyalgia	16.5%
56	Polymyalgia Rheumatica	16.5%
57	Bone Diseases, Endocrine	16%
58	Rheumatoid Nodule	15.9%
59	Bone Diseases	15.8%
60	Bone Diseases, Infectious	15.6%
61	Bone neoplasms	15.6%
62	Osteopenia	15.6%
63	Pectus excavatum	15.4%
64	Bone Resorption	15.4%
65	Aseptic Necrosis of Bone	15.4%
66	Temporomandibular Joint Dysfunction Syndrome	14.7%
67	Gigantism	14.5%
68	Tuberculosis, Spinal	14.4%
69	Felty Syndrome	13.7%
70	Klippel-Feil Syndrome	12.6%
71	Synostosis	12.6%
72	Myofascial Pain Syndromes	12.2%
73	Rhabdomyolysis	12.2%
74	Hip Dislocation	12.1%
75	Shoulder Dislocation	12.1%
76	Hip Dysplasia	12.1%
77	Rheumatoid Vasculitis	12%
78	Ankylosing spondylitis	11.3%
79	Spondylitis	10.8%
80	Ainhum	10.8%
81	Dysostoses	10.8%
82	Sicca Syndrome	10.7%
83	Sjogren's Syndrome	10.7%
84	Lordosis	10.7%
85	Spondylolysis	10.7%
86	kyphosis	10.7%
87	Talipes	10%
88	Shoulder Pain	10%
89	Compartment syndromes	9.9%
90	Maxillary Diseases	9.9%
91	Tendinitis	9.9%
92	Tendinopathy	9.9%
93	Myositis	9.8%
94	Tietze's Syndrome	9.8%
95	Limb Deformities, Congenital	9.8%
96	Isaacs syndrome	9.8%
97	Craniofacial Abnormalities	9.8%
98	Myotonic Disorders	9.8%
99	Eosinophilic Granuloma	9.5%
100	Craniosynostosis	9.4%
101	Syndactyly	9.4%
102	Brachycephaly	9.4%
103	Craniofacial Dysostosis	9.2%
104	Congenital Hypothyroidism	8.9%
105	Spondylarthropathies	8.8%
106	Multiple Epiphyseal Dysplasia	8.8%
107	Osteochondrodysplasias	8.8%
108	Spinal Diseases	8.7%
109	Osteomyelitis	8.6%
110	Osteoporosis	8.6%
111	Periostitis	8.6%
112	Bone Demineralization, Pathologic	8.6%
113	Post-Traumatic Osteoporosis	8.6%
114	Alveolar Bone Loss	8.6%
115	Femur Head Necrosis	8.6%
116	Osteolysis	8.6%
117	Medial Tibial Stress Syndrome	8.2%
118	Mitochondrial Myopathies	8.1%
119	Muscle Cramp	8.1%
120	Eosinophilia-Myalgia Syndrome	8.1%
121	Gastroschisis	8.1%
122	Muscle Rigidity	8%
123	Muscle Spasticity	8%
124	Cogwheel Rigidity	8%
125	Nuchal Rigidity	8%
126	Acrocephalosyndactylia	7.9%
127	Dwarfism	7.6%
128	Jaw Abnormalities	7.5%
129	Chronic Fatigue Syndrome	7.3%
130	Acromegaly	7.2%
131	Joint Tuberculosis	7.2%
132	Tuberculosis, Osteoarticular	7.2%
133	Bone Tuberculosis	7.2%
134	Bunion	7.1%
135	Fibrodysplasia Ossificans Progressiva	7.1%
136	Myoglobinuria	7.1%
137	Myositis Ossificans	7.1%
138	Tenosynovitis	7.1%
139	Arthropathy	7%
140	Giant Cell Epulis	7%
141	Muscle Weakness	7%
142	Spondylolisthesis	7%
143	Musculoskeletal Pain	6.9%
144	Familial Periodic Paralysis	6.9%
145	Congenital clubfoot	6.9%
146	Vertical Talus	6.9%
147	Chondrodysplasia Punctata	6.6%
148	Enchondromatosis	6.6%
149	Osteosclerosis	6.6%
150	Kashin-Beck Disease	6.6%
151	Prognathism	6.4%
152	Poland Syndrome	6.4%
153	Laryngomalacia	6.2%
154	Rickets	6.2%
155	Myalgia	6%
156	Antley-Bixler Syndrome Phenotype	5.9%
157	Anterior Compartment Syndrome	5.7%
158	Enthesopathy	5.7%
159	Abdominal Compartment Syndrome	5.7%
160	Amelia	5.7%
161	Arachnodactyly	5.7%
162	Ectromelia	5.7%
163	Hemimelia	5.7%
164	Phocomelia	5.7%
165	Sirenomelia	5.7%
166	Polymyositis	5.7%
167	Polydactyly	5.7%
168	Brachydactyly	5.7%
169	Plagiocephaly	5.7%
170	Lower Extremity Deformities, Congenital	5.7%
171	Upper Extremity Deformities, Congenital	5.7%
172	Rubinstein-Taybi Syndrome	5.6%
173	Pseudohypoparathyroidism	5.4%
174	Osteoporosis, Postmenopausal	5.3%
175	Mandibulofacial Dysostosis	5.3%
176	Palatal Neoplasms	5.2%
177	Basal Cell Nevus Syndrome	5.2%
178	Muscular Dystrophy	4.8%
179	Orbital Myositis	4.8%
180	Dupuytren Contracture	4.8%
181	Pyomyositis	4.7%
182	Myotonic Dystrophy	4.7%
183	Micrognathism	4.7%
184	Pierre Robin Syndrome	4.7%
185	Goldenhar Syndrome	4.6%
186	Melorheostosis	4.6%
187	Osteopetrosis	4.6%
188	Osteogenesis Imperfecta	4.5%
189	Mastoiditis	4.4%
190	Petrositis	4.4%
191	Marfan Syndrome	4.4%
192	Retrognathia	4.2%
193	Maxillofacial Abnormalities	4.1%
194	Myotonia Congenita	4.1%
195	Bronchomalacia	4.1%
196	Tracheomalacia	4.1%
197	Microcephaly	4%
198	Macrocephaly	4%
199	Hypokalemic periodic paralysis	4%
200	Osteomalacia	3.8%
201	Mitochondrial Encephalomyopathies	3.6%
202	Cleft Palate	3.5%
203	Noonan Syndrome	3.2%
204	Welander Distal Myopathy	3.1%
205	Cockayne Syndrome	3%
206	Holoprosencephaly	2.9%
207	Nose Neoplasms	2.8%
208	Dermatomyositis	2.7%
209	Muscular Dystrophy, Duchenne	2.7%
210	Renal Osteodystrophy	2.7%
211	Renal rickets	2.7%
212	Porencephaly	2.6%
213	Radicular Cyst	1.7%
214	MELAS Syndrome	1.5%
215	Kearns-Sayre syndrome	1.4%
216	Familial Hypophosphatemic Rickets	1.2%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237