MetaADEDB 2.0 @ LMMD
Tadenan
(NOPFSRXAKWQILS-UHFFFAOYSA-N)
Structure
SMILES
CCCCCCCCCCCCCCCCCCCCCCO
Type(s)
Approved; Investigational
ATC code(s)
D06BB11
Molecular Formula:
C22H46O
Molecular Weight:
326.600
Log P:
7.8006
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
1
TPSA:
20.23
CAS Number(s):
661-19-8; 30303-65-2
Synonym(s)
1.
Tadenan
2.
V-1326
External Link(s)
MeSHC009375
PubChem Compound12620
ChEBI31000
CHEMBLCHEMBL1200453
DrugBankDB00632
DrugCentral940
KEGGdr:D03884
Therapeutic Target DatabaseD00AOJ
ZINC6920384
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 5609
Canada Vigilance: 164
Canada Vigilance
OFFSIDES
US FAERS
2Drug administration errorFAERS: 1739OFFSIDES
US FAERS
3Incorrect drug administration durationFAERS: 825US FAERS
4Product quality issueFAERS: 597
Canada Vigilance: 4
Canada Vigilance
US FAERS
5Inappropriate schedule of drug administrationFAERS: 503US FAERS
6Lip swellingFAERS: 435
Canada Vigilance: 4
Canada Vigilance
US FAERS
7Application site painFAERS: 412US FAERS
8Wrong technique in product usage processFAERS: 352
Canada Vigilance: 1
Canada Vigilance
US FAERS
9HypersensitivityFAERS: 259
Canada Vigilance: 1
Canada Vigilance
US FAERS
10Incorrect product administration durationFAERS: 237
Canada Vigilance: 1
Canada Vigilance
US FAERS
11Application site erythemaFAERS: 221US FAERS
12Application site irritationFAERS: 213OFFSIDES
US FAERS
13Application site swellingFAERS: 189
Canada Vigilance: 1
Canada Vigilance
US FAERS
14Inappropriate schedule of product administrationFAERS: 158
Canada Vigilance: 2
Canada Vigilance
US FAERS
15Application site scabFAERS: 153US FAERS
16Intentional drug misuseFAERS: 151OFFSIDES
US FAERS
17CheilitisFAERS: 129OFFSIDES
US FAERS
18Expired product administeredFAERS: 116US FAERS
19Application site reactionFAERS: 113OFFSIDES
SIDER
US FAERS
20Product complaintFAERS: 112
Canada Vigilance: 13
Canada Vigilance
US FAERS
21Application site scarFAERS: 94US FAERS
22Burning sensationFAERS: 81US FAERS
23Product use in unapproved indicationFAERS: 78US FAERS
24Product use issueFAERS: 78
Canada Vigilance: 5
Canada Vigilance
US FAERS
25Application site vesiclesFAERS: 77US FAERS
26Application site pruritusFAERS: 76US FAERS
27ScabFAERS: 73
Canada Vigilance: 1
Canada Vigilance
US FAERS
28PainFAERS: 67US FAERS
29ErythemaFAERS: 66
Canada Vigilance: 1
Canada Vigilance
US FAERS
30PruritusFAERS: 64
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
31Accidental exposure to productFAERS: 59
Canada Vigilance: 1
Canada Vigilance
US FAERS
32Application site drynessFAERS: 59OFFSIDES
US FAERS
33Lip exfoliationFAERS: 43US FAERS
34Application site burnFAERS: 36US FAERS
35Drug effective for unapproved indicationFAERS: 34US FAERS
36Drug administered at inappropriate siteFAERS: 33US FAERS
37Application site exfoliationFAERS: 32US FAERS
38Drug effect delayedFAERS: 32US FAERS
39Application site infectionFAERS: 31US FAERS
40HeadacheFAERS: 31SIDER
US FAERS
41Product administered at inappropriate siteFAERS: 30US FAERS
42Oral painFAERS: 29
Canada Vigilance: 2
Canada Vigilance
US FAERS
43Adverse eventFAERS: 28US FAERS
44Drug ineffective for unapproved indicationFAERS: 28US FAERS
45Nonspecific reactionFAERS: 27US FAERS
46SwellingFAERS: 26US FAERS
47UrticariaFAERS: 26US FAERS
48Therapeutic response unexpectedFAERS: 25US FAERS
49Drug effect incompleteFAERS: 24US FAERS
50Application site rashFAERS: 23US FAERS
51Pharmaceutical product complaintFAERS: 23US FAERS
52Application site dischargeFAERS: 19US FAERS
53DizzinessFAERS: 19US FAERS
54Expired drug administeredFAERS: 19US FAERS
55Skin lacerationFAERS: 19US FAERS
56Facial PainFAERS: 18US FAERS
57Lip pruritusFAERS: 17
Canada Vigilance: 1
Canada Vigilance
US FAERS
58Product package associated injuryFAERS: 17US FAERS
59InfectionFAERS: 16US FAERS
60Application site discomfortFAERS: 15US FAERS
61Application site inflammationFAERS: 14US FAERS
62Lip erythemaFAERS: 14
Canada Vigilance: 1
Canada Vigilance
US FAERS
63MalaiseFAERS: 14US FAERS
64Skin irritationFAERS: 14US FAERS
65StomatitisFAERS: 14US FAERS
66LacerationFAERS: 13US FAERS
67AcneFAERS: 12SIDER
US FAERS
68Application site papulesFAERS: 12US FAERS
69Drug administered to patient of inappropriate ageFAERS: 12US FAERS
70Dry skinFAERS: 12SIDER
US FAERS
71Eye painFAERS: 12US FAERS
72Inadequate aseptic technique in use of productFAERS: 12US FAERS
73Mouth swellingFAERS: 12US FAERS
74Feeling abnormalFAERS: 11US FAERS
75Intentional product use issueFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
76LymphadenopathyFAERS: 11US FAERS
77Medication ErrorFAERS: 11US FAERS
78Application site erosionFAERS: 10US FAERS
79Application site warmthFAERS: 10US FAERS
80Incorrect dose administeredFAERS: 10US FAERS
81Lip InfectionFAERS: 10US FAERS
82NauseaFAERS: 10
Canada Vigilance: 1
Canada Vigilance
US FAERS
83PallorFAERS: 10OFFSIDES
US FAERS
84Eye irritationFAERS: 9US FAERS
85Incorrect route of drug administrationFAERS: 9US FAERS
86Skin UlcerFAERS: 9US FAERS
87Thermal burnFAERS: 9US FAERS
88Application site ulcerFAERS: 8US FAERS
89DiscomfortFAERS: 8US FAERS
90Drug exposure during pregnancyFAERS: 8US FAERS
91DysgeusiaFAERS: 8US FAERS
92Product physical consistency issueFAERS: 8US FAERS
93Intentional misuseFAERS: 7OFFSIDES
US FAERS
94Intentional product misuseFAERS: 7
Canada Vigilance: 1
Canada Vigilance
US FAERS
95Pigmentation lipFAERS: 7US FAERS
96Circumstance or information capable of leading to medication errorFAERS: 6US FAERS
97Emergency care examinationFAERS: 6US FAERS
98Hypoaesthesia facialFAERS: 6US FAERS
99Product storage errorFAERS: 6US FAERS
100AphasiaFAERS: 5US FAERS
101Blood blisterFAERS: 5US FAERS
102FatigueFAERS: 5US FAERS
103Purulent dischargeFAERS: 5US FAERS
104Rash erythematousFAERS: 5US FAERS
105TensionFAERS: 5US FAERS
106Application site indurationFAERS: 4US FAERS
107Application site pustulesFAERS: 4US FAERS
108Drug effect variableFAERS: 4US FAERS
109Extra dose administeredFAERS: 4US FAERS
110InflammationFAERS: 4US FAERS
111NasopharyngitisFAERS: 4US FAERS
112Oropharyngeal painFAERS: 4US FAERS
113OverdoseFAERS: 4US FAERS
114Product packaging quantity issueFAERS: 4US FAERS
115Accidental exposure to product by childFAERS: 3US FAERS
116AnxietyFAERS: 3US FAERS
117Blister ruptureFAERS: 3US FAERS
118Breast FeedingFAERS: 3US FAERS
119Concomitant disease aggravatedFAERS: 3US FAERS
120DermatitisFAERS: 3SIDER
US FAERS
121Disease recurrenceFAERS: 3US FAERS
122GlossitisFAERS: 3US FAERS
123Intercepted medication errorFAERS: 3US FAERS
124Medication residue presentFAERS: 3US FAERS
125Muscle tightnessFAERS: 3US FAERS
126Pharyngolaryngeal PainFAERS: 3US FAERS
127Poor quality sleepFAERS: 3US FAERS
128Product packaging issueFAERS: 3US FAERS
129Product use complaintFAERS: 3US FAERS
130SunburnFAERS: 3US FAERS
131Therapeutic product effect delayedFAERS: 3US FAERS
132ToothacheFAERS: 3US FAERS
133VIIth nerve paralysisFAERS: 3OFFSIDES
US FAERS
134VomitingFAERS: 3US FAERS
135Weight decreasedFAERS: 3US FAERS
136Abdominal discomfortFAERS: 2US FAERS
137Accidental exposureFAERS: 2US FAERS
138Aphthous StomatitisFAERS: 2US FAERS
139Application site injuryFAERS: 2US FAERS
140Application site lacerationFAERS: 2US FAERS
141Application site urticariaFAERS: 2US FAERS
142Application site woundFAERS: 2US FAERS
143ArthralgiaFAERS: 2US FAERS
144Auricular swellingFAERS: 2US FAERS
145Blunted affectFAERS: 2US FAERS
146Cerebrovascular accidentFAERS: 2US FAERS
147DysphoniaFAERS: 2US FAERS
148Exposure during breast feedingFAERS: 2US FAERS
149Feeling ColdFAERS: 2US FAERS
150GingivitisFAERS: 2US FAERS
151IndurationFAERS: 2US FAERS
152Live BirthFAERS: 2US FAERS
153Nasal discomfortFAERS: 2US FAERS
154Nasal pruritusFAERS: 2US FAERS
155Neck PainFAERS: 2US FAERS
156NeuralgiaFAERS: 2US FAERS
157Oral infectionFAERS: 2US FAERS
158Oral pruritusFAERS: 2US FAERS
159OsteitisFAERS: 2US FAERS
160Pain of skinFAERS: 2US FAERS
161Penile burning sensationFAERS: 2US FAERS
162Peripheral swellingFAERS: 2US FAERS
163Product administered to patient of inappropriate ageFAERS: 2US FAERS
164Product container issueFAERS: 2US FAERS
165Product dispensing errorFAERS: 2US FAERS
166Product expiration date issueFAERS: 2US FAERS
167Product outer packaging issueFAERS: 2US FAERS
168Skin IndurationFAERS: 2US FAERS
169Skin tightnessFAERS: 2US FAERS
170Squamous cell carcinomaFAERS: 2US FAERS
171Therapeutic product effect incompleteFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
172Tongue discomfortFAERS: 2US FAERS
173Tongue erythemaFAERS: 2US FAERS
174Tongue pruritusFAERS: 2US FAERS
175Upper respiratory tract congestionFAERS: 2US FAERS
176furuncleFAERS: 2US FAERS
177Abdominal PainFAERS: 1US FAERS
178AbscessFAERS: 1US FAERS
179AgeusiaFAERS: 1US FAERS
180AgitationFAERS: 1US FAERS
181Alcohol test false positiveFAERS: 1US FAERS
182AlopeciaFAERS: 1US FAERS
183AmblyopiaFAERS: 1US FAERS
184Anaphylactic shockFAERS: 1US FAERS
185Angular cheilitisFAERS: 1US FAERS
186Anorectal discomfortFAERS: 1US FAERS
187Application site excoriationFAERS: 1US FAERS
188AsthmaFAERS: 1US FAERS
189BiopsyFAERS: 1US FAERS
190Blood glucose decreasedFAERS: 1US FAERS
191Bone painFAERS: 1US FAERS
192Buccal mucosal rougheningFAERS: 1US FAERS
193CellulitisFAERS: 1US FAERS
194Chemical injuryFAERS: 1US FAERS
195Chest PainFAERS: 1US FAERS
196CystitisFAERS: 1US FAERS
197DeformityFAERS: 1US FAERS
198DehydrationFAERS: 1US FAERS
199Device operational issueFAERS: 1US FAERS
200Device use errorFAERS: 1US FAERS
201DisabilityFAERS: 1US FAERS
202Drug DependenceFAERS: 1US FAERS
203Drug abuseFAERS: 1US FAERS
204Drug dose omissionFAERS: 1US FAERS
205DysarthriaFAERS: 1US FAERS
206Ear discomfortFAERS: 1US FAERS
207Emergency CareFAERS: 1US FAERS
208Enlarged uvulaFAERS: 1US FAERS
209EpistaxisFAERS: 1US FAERS
210Essential HypertensionFAERS: 1US FAERS
211ExcoriationFAERS: 1US FAERS
212Eye InfectionFAERS: 1US FAERS
213Eye inflammationFAERS: 1US FAERS
214Eyelid Function DisorderFAERS: 1US FAERS
215Eyelids pruritusFAERS: 1US FAERS
216Feeling jitteryFAERS: 1US FAERS
217Foreign body sensation in eyesFAERS: 1US FAERS
218Genital burning sensationFAERS: 1US FAERS
219Genital painFAERS: 1US FAERS
220Genital rashFAERS: 1US FAERS
221Gingival AtrophyFAERS: 1US FAERS
222Gingival erythemaFAERS: 1US FAERS
223Head discomfortFAERS: 1US FAERS
224Impaired work abilityFAERS: 1US FAERS
225ImpetigoFAERS: 1US FAERS
226Initial insomniaFAERS: 1US FAERS
227KeratitisFAERS: 1US FAERS
228LethargyFAERS: 1US FAERS
229Limb injuryFAERS: 1US FAERS
230LymphadenitisFAERS: 1US FAERS
231Medication residueFAERS: 1US FAERS
232Mole excisionFAERS: 1US FAERS
233Musculoskeletal stiffnessFAERS: 1US FAERS
234NervousnessFAERS: 1US FAERS
235No adverse eventFAERS: 1US FAERS
236OnychoclasisFAERS: 1US FAERS
237Open woundFAERS: 1US FAERS
238Oral dischargeFAERS: 1US FAERS
239Oral fungal infectionFAERS: 1US FAERS
240Oral mucosal eruptionFAERS: 1US FAERS
241Oral mucosal erythemaFAERS: 1US FAERS
242Oral mucosal exfoliationFAERS: 1US FAERS
243Oropharyngeal discomfortFAERS: 1US FAERS
244OsteomyelitisFAERS: 1US FAERS
245Pharyngolaryngeal discomfortFAERS: 1US FAERS
246Physical assaultFAERS: 1US FAERS
247PiloerectionFAERS: 1US FAERS
248Product dispensing issueFAERS: 1US FAERS
249Product lot number issueFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
250Product packaging difficult to openFAERS: 1US FAERS
251Product physical issueFAERS: 1US FAERS
252Product residue presentFAERS: 1US FAERS
253Product tamperingFAERS: 1US FAERS
254Productive CoughFAERS: 1US FAERS
255Pulmonary congestionFAERS: 1US FAERS
256Saliva alteredFAERS: 1US FAERS
257Sensation of blood flowFAERS: 1US FAERS
258Skin hypertrophyFAERS: 1US FAERS
259Skin lesionFAERS: 1US FAERS
260Soft Tissue InfectionFAERS: 1US FAERS
261SomnolenceFAERS: 1US FAERS
262Submandibular massFAERS: 1US FAERS
263Swelling of eyelidFAERS: 1US FAERS
264Symptom recurrenceFAERS: 1US FAERS
265Therapy non-responderFAERS: 1US FAERS
266Throat irritationFAERS: 1US FAERS
267TinnitusFAERS: 1US FAERS
268Tongue blisteringFAERS: 1US FAERS
269TremorFAERS: 1US FAERS
270UlcerFAERS: 1US FAERS
271Unevaluable eventFAERS: 1US FAERS
272WheezingFAERS: 1US FAERS
273Wrong technique in device usage processFAERS: 1US FAERS
274ApneaOFFSIDES
275Bacterial sepsisOFFSIDES
276BronchomalaciaOFFSIDES
277Congenital heart diseaseOFFSIDES
278Congenital tracheomalaciaOFFSIDES
279Conjunctival depositOFFSIDES
280Erythema MultiformeOFFSIDES
281Facial paralysisCanada Vigilance: 1Canada Vigilance
282LaryngomalaciaOFFSIDES
283Mechanical ventilationOFFSIDES
284Mucosal erosionOFFSIDES
285PROTHROMBIN TIMEOFFSIDES
286Product administration errorCanada Vigilance: 3Canada Vigilance
287Renal tubular disorderOFFSIDES
288Renal tubular necrosisOFFSIDES
289Respiratory FailureOFFSIDES
290Right Ventricular HypertrophyOFFSIDES
291Testicular massOFFSIDES
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