MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Arthritis, Reactive

(UMLS:C0085435)

Definition:: An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.
UMLS ID:: C0085435
MeSH ID:: D016918

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.539.100.500

Classification 2:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.900.853.625.800.637|C05.550.114.099.500|C05.550.114.865.800.637

Synonym(s)

Arthritis, Reactive

Arthritis occurring after infection

Arthritis reactive

Post-bacterial arthropathy

Post-infective arthritis

Post-infective arthropathy

Reactive Arthritis

Reactive arthritis

infectious; arthritis, postinfective reaction (etiology)

10.

infectious; arthritis, postinfective reaction (manifestation)

11.

reactive arthritis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Methotrexate		5150075	CTD
2	Penicillamine		3396226	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Arthritis, Psoriatic	46.9%
2	Ankylosing spondylitis	43.4%
3	Osteoarthritis, Spine	39.2%
4	Periarthritis	32.3%
5	Osteoarthropathy, Secondary Hypertrophic	30.5%
6	Rheumatic Fever	27%
7	Gout	26.7%
8	Sacroiliitis	26.4%
9	Contracture	25.8%
10	Arthrogryposis	25.3%
11	Rheumatoid Arthritis	22.7%
12	Juvenile arthritis	22.7%
13	Bone Diseases, Infectious	22.3%
14	Arthritis, Experimental	22.1%
15	Metatarsalgia	22%
16	Bursitis	21.5%
17	Joint Instability	21.5%
18	Synovitis	21.5%
19	Joint laxity	21.5%
20	Frozen shoulder	21.5%
21	Patellofemoral Pain Syndrome	21.5%
22	Osteoarthritis, Knee	18.1%
23	Hemarthrosis	18%
24	Discitis	17.7%
25	Fasciitis	17.4%
26	Foot Deformities	17.4%
27	Osteochondritis	17.1%
28	Temporomandibular Joint Disorders	16.9%
29	Platybasia	16.8%
30	Tuberculosis, Spinal	16.3%
31	Arthritis, Gouty	16.2%
32	Spinal Neoplasms	15.6%
33	Rheumatoid Nodule	15.5%
34	Fasciitis, Plantar	15.3%
35	Jaw Diseases	14.9%
36	Pectus carinatum	14.7%
37	Bone Diseases, Developmental	14.6%
38	Hyperostosis	14.6%
39	Osteitis	14.6%
40	Osteitis Deformans	14.6%
41	Osteochondrosis	14.6%
42	Cartilage Diseases	14.6%
43	Foot Diseases	14.6%
44	Myopathy	14.6%
45	Rheumatism	14.6%
46	Chondromalacia	14.6%
47	Hip Contracture	14.4%
48	Ischemic contracture	14%
49	Spondylitis	13.9%
50	Spinal Stenosis	13.8%
51	Spondylosis	13.8%
52	Intervertebral Disc Degeneration	13.8%
53	Nail-Patella Syndrome	13.6%
54	Felty Syndrome	13.6%
55	Arthralgia	13.4%
56	Polyarthralgia	13.4%
57	Osteomyelitis	13.2%
58	Periostitis	13.2%
59	Fibromyalgia	13.1%
60	Polymyalgia Rheumatica	13.1%
61	Bone Diseases, Endocrine	12.6%
62	Bone neoplasms	12.3%
63	Osteopenia	12.3%
64	Joint Tuberculosis	12.3%
65	Tuberculosis, Osteoarticular	12.3%
66	Bone Tuberculosis	12.3%
67	Pectus excavatum	12.2%
68	Bone Resorption	12.2%
69	Aseptic Necrosis of Bone	12.2%
70	Rheumatoid Vasculitis	12.1%
71	Pelvic Infection	11.8%
72	Wound Infection	11.8%
73	Soft Tissue Infection	11.8%
74	Community-Acquired Infections	11.8%
75	Bone Diseases	11.8%
76	Gigantism	11.4%
77	Temporomandibular Joint Dysfunction Syndrome	11.3%
78	Sicca Syndrome	10.9%
79	Sjogren's Syndrome	10.9%
80	Arthritis, Infectious	10.8%
81	Eye Infection	10.2%
82	Respiratory Tract Infections	10.2%
83	Arthritis, Reactive	10.1%
84	Pregnancy Complications, Infectious	10%
85	Skin Diseases, Infectious	10%
86	Suppuration	9.9%
87	Cellulitis	9.9%
88	Klippel-Feil Syndrome	9.8%
89	Synostosis	9.8%
90	Cross Infection	9.8%
91	Septicemia	9.8%
92	Sepsis	9.8%
93	Endotoxemia	9.7%
94	Ulcerative stomatitis	9.5%
95	Spondylarthropathies	9.5%
96	Pyomyositis	9.2%
97	Myofascial Pain Syndromes	9%
98	Rhabdomyolysis	9%
99	Hidradenitis Suppurativa	9%
100	Opportunistic Infections	9%
101	Hip Dislocation	8.9%
102	Shoulder Dislocation	8.9%
103	Hip Dysplasia	8.9%
104	Urinary tract infection	8.6%
105	Dermatomycoses	8.5%
106	Skin Diseases, Bacterial	8.5%
107	Bacteremia	8.4%
108	Mycetoma	8.4%
109	Eosinophilic Granuloma	8.1%
110	Ainhum	7.9%
111	Dysostoses	7.9%
112	Lordosis	7.9%
113	Spondylolysis	7.9%
114	kyphosis	7.9%
115	Sexually Transmitted Diseases	7.7%
116	Compartment syndromes	7.6%
117	Maxillary Diseases	7.6%
118	Tendinitis	7.6%
119	Tendinopathy	7.6%
120	Talipes	7.6%
121	Myositis	7.5%
122	Tietze's Syndrome	7.5%
123	Limb Deformities, Congenital	7.5%
124	Isaacs syndrome	7.5%
125	Craniofacial Abnormalities	7.5%
126	Myotonic Disorders	7.5%
127	Shoulder Pain	7.5%
128	Bacterial Endocarditis	7.5%
129	Mastoiditis	7.5%
130	Petrositis	7.5%
131	Fungemia	7.4%
132	Craniosynostosis	7.3%
133	Syndactyly	7.3%
134	Brachycephaly	7.3%
135	Congenital Hypothyroidism	7.1%
136	Pertussis	7%
137	Craniofacial Dysostosis	6.9%
138	Candidiasis, Chronic Mucocutaneous	6.9%
139	Cutaneous Candidiasis	6.9%
140	Bacterial Infections	6.7%
141	Mycoses	6.7%
142	Multiple Epiphyseal Dysplasia	6.7%
143	Osteochondrodysplasias	6.7%
144	Osteoporosis	6.6%
145	Bone Demineralization, Pathologic	6.6%
146	Post-Traumatic Osteoporosis	6.6%
147	Alveolar Bone Loss	6.6%
148	Femur Head Necrosis	6.6%
149	Osteolysis	6.6%
150	Endophthalmitis	6.6%
151	Peritonitis	6.6%
152	Medial Tibial Stress Syndrome	6.5%
153	Surgical Wound Infection	6.5%
154	Mitochondrial Myopathies	6.5%
155	Abscess	6.5%
156	Adnexitis	6.5%
157	Empyema	6.5%
158	Pelvic Inflammatory Disease	6.5%
159	Erysipelas	6.5%
160	Staphylococcal Skin Infections	6.5%
161	Muscle Cramp	6.4%
162	Eosinophilia-Myalgia Syndrome	6.4%
163	Gastroschisis	6.4%
164	Candidemia	6.4%
165	Muscle Rigidity	6.4%
166	Muscle Spasticity	6.4%
167	Cogwheel Rigidity	6.4%
168	Nuchal Rigidity	6.4%
169	Erythrasma	6.3%
170	Spinal Diseases	6.2%
171	Brain Abscess	6.2%
172	Panophthalmitis	6.1%
173	Syphilis	6.1%
174	Jaw Abnormalities	6.1%
175	Erythema Chronicum Migrans	6%
176	Chromoblastomycosis	6%
177	Dermatophytosis	6%
178	Sporotrichosis	6%
179	Tinea	6%
180	Tinea Versicolor	6%
181	Trichophytosis	6%
182	Hyalohyphomycosis	6%
183	Acrocephalosyndactylia	5.9%
184	Dwarfism	5.9%
185	Chronic Fatigue Syndrome	5.9%
186	Psoas Abscess	5.8%
187	Abdominal Abscess	5.8%
188	Ecthyma	5.8%
189	Subacute Bacterial Endocarditis	5.8%
190	Chlamydia Infections	5.7%
191	Gonorrhea	5.7%
192	Superinfection	5.7%
193	Central Nervous System Bacterial Infections	5.7%
194	Giant Cell Epulis	5.7%
195	Muscle Weakness	5.7%
196	Impetigo	5.7%
197	Central Nervous System Infection	5.7%
198	Acromegaly	5.7%
199	Corneal Ulcer	5.7%
200	Musculoskeletal Pain	5.7%
201	Familial Periodic Paralysis	5.6%
202	Puerperal Infection	5.6%
203	Appendicitis	5.6%
204	Bacteriuria	5.6%
205	Pyuria	5.6%
206	Arthropathy	5.6%
207	Blastomycosis	5.6%
208	Endotoxic shock	5.5%
209	Septic Shock	5.5%
210	Toxic Shock Syndrome	5.5%
211	Hordeolum	5.3%
212	Bacterial conjunctivitis	5.3%
213	Staphylococcal Scalded Skin Syndrome	5.2%
214	Laryngomalacia	5.1%
215	Prognathism	5.1%
216	Bunion	5%
217	Fibrodysplasia Ossificans Progressiva	5%
218	Myoglobinuria	5%
219	Myositis Ossificans	5%
220	Tenosynovitis	5%
221	Myalgia	5%
222	Rickets	5%
223	Spondylolisthesis	5%
224	Diverticulitis	4.8%
225	Fusariosis	4.8%
226	Congenital clubfoot	4.8%
227	Vertical Talus	4.8%
228	Furunculosis	4.7%
229	furuncle	4.7%
230	Rhinoscleroma	4.7%
231	Chondrodysplasia Punctata	4.7%
232	Enchondromatosis	4.7%
233	Osteosclerosis	4.7%
234	Kashin-Beck Disease	4.7%
235	Poland Syndrome	4.6%
236	Lymphogranuloma Venereum	4.6%
237	carbuncle	4.6%
238	Antley-Bixler Syndrome Phenotype	4.5%
239	Rubinstein-Taybi Syndrome	4.4%
240	Pseudohypoparathyroidism	4.4%
241	AIDS-Related Opportunistic Infections	4.4%
242	Borrelia Infections	4.3%
243	Leptospirosis	4.3%
244	Basal Cell Nevus Syndrome	4.3%
245	Lung Abscess	4.3%
246	Tinea Capitis	4.2%
247	Onychomycosis	4.2%
248	Ophthalmia Neonatorum	4.2%
249	Trachoma	4.2%
250	Anterior Compartment Syndrome	4.2%
251	Enthesopathy	4.2%
252	Abdominal Compartment Syndrome	4.2%
253	Diverticulum	4.2%
254	Diverticulosis	4.2%
255	Amelia	4.2%
256	Arachnodactyly	4.2%
257	Ectromelia	4.2%
258	Hemimelia	4.2%
259	Phocomelia	4.2%
260	Sirenomelia	4.2%
261	Polymyositis	4.2%
262	Polydactyly	4.2%
263	Brachydactyly	4.2%
264	Plagiocephaly	4.2%
265	Lower Extremity Deformities, Congenital	4.2%
266	Upper Extremity Deformities, Congenital	4.2%
267	Lyme Disease	4.1%
268	Relapsing Fever	4.1%
269	Lyme Neuroborreliosis	4.1%
270	Liver Abscess	4.1%
271	Palatal Neoplasms	4.1%
272	Aspergillosis	3.9%
273	Candidiasis	3.9%
274	Coccidioidomycosis	3.9%
275	Histoplasmosis	3.9%
276	Paracoccidioidomycosis	3.9%
277	Zygomycosis	3.9%
278	Gram-Negative Bacterial Infections	3.9%
279	Gram-Positive Bacterial Infections	3.9%
280	Phaeohyphomycosis	3.9%
281	Pneumocystis Infections	3.9%
282	Osteoporosis, Postmenopausal	3.9%
283	Mandibulofacial Dysostosis	3.8%
284	Tinea Pedis	3.7%
285	Neuroaspergillosis	3.7%
286	Erythema Induratum	3.7%
287	Myotonic Dystrophy	3.7%
288	Marfan Syndrome	3.7%
289	Retropharyngeal Abscess	3.7%
290	Epidural Abscess	3.7%
291	Muscular Dystrophy	3.6%
292	Orbital Myositis	3.6%
293	Neurosyphilis	3.6%
294	Peritonsillar Abscess	3.6%
295	Dupuytren Contracture	3.6%
296	Micrognathism	3.5%
297	Pierre Robin Syndrome	3.5%
298	Osteogenesis Imperfecta	3.4%
299	Toxoplasmosis, Cerebral	3.4%
300	Otomycosis	3.3%
301	Piedra	3.3%
302	Central Nervous System Fungal Infections	3.3%
303	Bacterial Vaginosis	3.3%
304	Invasive Pulmonary Aspergillosis	3.2%
305	Retrognathia	3.2%
306	Human Ehrlichiosis	3.2%
307	Maxillofacial Abnormalities	3.2%
308	Myotonia Congenita	3.2%
309	Bronchomalacia	3.1%
310	Tracheomalacia	3.1%
311	Microcephaly	3.1%
312	Macrocephaly	3.1%
313	Hypokalemic periodic paralysis	3.1%
314	Goldenhar Syndrome	3.1%
315	Melorheostosis	3%
316	Osteopetrosis	3%
317	Japanese Spotted Fever	2.9%
318	Osteomalacia	2.9%
319	Lung Diseases, Fungal	2.9%
320	Human anaplasmosis	2.9%
321	Pneumonia, Bacterial	2.8%
322	Meningitis, Cryptococcal	2.8%
323	Mitochondrial Encephalomyopathies	2.8%
324	Arthritis	2.8%
325	Polyarthritis	2.8%
326	Cleft Palate	2.7%
327	Actinomycetales Infections	2.6%
328	Bordetella Infections	2.6%
329	Brucellosis	2.6%
330	Campylobacter infection	2.6%
331	Clostridium Infections	2.6%
332	Enterobacteriaceae Infections	2.6%
333	Listeriosis	2.6%
334	Mucormycosis	2.6%
335	Pseudomonas Infections	2.6%
336	Q Fever	2.6%
337	Staphylococcal Infections	2.6%
338	Streptococcal Infections	2.6%
339	Vibrio Infections	2.6%
340	Helicobacter Infections	2.6%
341	Bacillaceae Infections	2.6%
342	Neisseriaceae Infections	2.6%
343	Burkholderia Infections	2.6%
344	Clostridium difficile infection	2.6%
345	Flavobacteriaceae Infections	2.6%
346	Moraxellaceae Infections	2.6%
347	Burkholderia cepacia Infection	2.6%
348	Noonan Syndrome	2.5%
349	Rocky Mountain Spotted Fever	2.5%
350	Liver Abscess, Amebic	2.5%
351	Meningitis, Listeria	2.4%
352	Cockayne Syndrome	2.4%
353	Syphilis, Congenital	2.3%
354	Holoprosencephaly	2.3%
355	Erysipelothrix infection	2.2%
356	Meningitis, Haemophilus	2.2%
357	Meningitis, Pneumococcal	2.2%
358	Nose Neoplasms	2.2%
359	Oral candidiasis	2.2%
360	Welander Distal Myopathy	2.2%
361	Pulmonary Aspergillosis	2.2%
362	Bronchopulmonary Aspergillosis	2.2%
363	Renal Osteodystrophy	2.1%
364	Renal rickets	2.1%
365	Dermatomyositis	2%
366	Acinetobacter Infections	1.9%
367	Actinomycosis	1.9%
368	Bacteroides Infections	1.9%
369	Cholera	1.9%
370	Corynebacterium Infections	1.9%
371	Escherichia coli Infections	1.9%
372	Gas Gangrene	1.9%
373	Haemophilus Infections	1.9%
374	Klebsiella Infections	1.9%
375	Meningococcal Infections	1.9%
376	Mycobacterium Infections	1.9%
377	Mycoplasma Infections	1.9%
378	Nocardia Infections	1.9%
379	Pasteurella Infections	1.9%
380	Pneumococcal Infections	1.9%
381	Proteus Infections	1.9%
382	Rickettsia Infections	1.9%
383	Salmonella infections	1.9%
384	Scarlet Fever	1.9%
385	Scrub Typhus	1.9%
386	Tetanus	1.9%
387	Serratia Infections	1.9%
388	Ureaplasma Infections	1.9%
389	Pulmonary Nocardiosis	1.9%
390	Muscular Dystrophy, Duchenne	1.9%
391	Porencephaly	1.9%
392	Meningitis, Bacterial	1.9%
393	Meningitis, Fungal	1.9%
394	Candidiasis, Vulvovaginal	1.8%
395	Tuberculosis, Meningeal	1.8%
396	Diphtheria	1.6%
397	Leprosy	1.6%
398	Mycobacterium Infections, Nontuberculous	1.6%
399	Psittacosis	1.6%
400	Paratyphoid Fever	1.6%
401	Plague	1.6%
402	Tuberculosis	1.6%
403	Typhoid Fever	1.6%
404	TYPHUS	1.6%
405	Yersinia pseudotuberculosis Infections	1.6%
406	Bubonic Plague	1.6%
407	Mycobacterium abscessus Infection	1.6%
408	Mycobacterium avium-intracellulare Infection	1.4%
409	Lymph Node Tuberculosis	1.4%
410	Tuberculosis, Miliary	1.4%
411	Tuberculosis, Multidrug-Resistant	1.4%
412	Leprosy, Multibacillary	1.4%
413	Latent Tuberculosis	1.4%
414	Salmonella Infections, Animal	1.4%
415	Enterocolitis, Pseudomembranous	1.4%
416	pseudomembranous colitis	1.4%
417	Dysentery, Bacillary	1.4%
418	Borderline leprosy	1.4%
419	Leprosy, Lepromatous	1.4%
420	Tuberculoid leprosy	1.4%
421	Extensively Drug-Resistant Tuberculosis	1.4%
422	Rheumatic Heart Disease	1.4%
423	Salmonella food poisoning	1.3%
424	Botulism	1.2%
425	Tuberculosis, Gastrointestinal	1.2%
426	Tuberculosis, Central Nervous System	1.2%
427	Waterhouse-Friderichsen Syndrome	1.2%
428	MELAS Syndrome	1.2%
429	Radicular Cyst	1.2%
430	Kearns-Sayre syndrome	1.1%
431	Aspergillosis, Allergic Bronchopulmonary	1.1%
432	Tuberculosis, Pulmonary	1.1%
433	Familial Hypophosphatemic Rickets	0.9%
434	Lemierre Syndrome	0.8%
435	Tuberculosis, Renal	0.8%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234