MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Severe Acute Respiratory Syndrome

(UMLS:C1175175)

Definition:: A viral disorder characterized by high FEVER, dry COUGH, shortness of breath (DYSPNEA) or breathing difficulties, and atypical PNEUMONIA. A virus in the genus CORONAVIRUS is the suspected agent.
UMLS ID:: C1175175
MeSH ID:: D045169

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.782.600.550.200.750

Classification 2:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.730.730

Synonym(s)

Severe Acute Respiratory Syndrome

Coronavirus Infections

SARS

SARS-CoV infection

SARS-associated coronavirus

Severe acute respiratory syndrome

coronavirus sars-associated

severe acute respiratory syndrome

severe acute respiratory syndrome (SARS)

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Oseltamivir	FAERS: 3		US FAERS
2	Lenalidomide	FAERS: 2		US FAERS
3	Abiraterone Acetate	FAERS: 1		US FAERS
4	Acetaminophen	FAERS: 1		US FAERS
5	Azacitidine	FAERS: 1		US FAERS
6	Doxycycline	FAERS: 1		US FAERS
7	Everolimus	FAERS: 1		US FAERS
8	Fenofibrate	FAERS: 1		US FAERS
9	Hydroxyurea	FAERS: 1		OFFSIDES US FAERS
10	Imatinib Mesylate	FAERS: 1		US FAERS
11	Penicillin V	FAERS: 1		US FAERS
12	Sitagliptin Phosphate	FAERS: 1		US FAERS
13	palbociclib	FAERS: 1		US FAERS
14	Atazanavir Sulfate			OFFSIDES
15	Cortisone			OFFSIDES
16	Cortisone			OFFSIDES
17	Dioctyl Sulfosuccinic Acid			OFFSIDES
18	Fludrocortisone			OFFSIDES
19	Methylprednisolone		15132791	CTD
20	Ribavirin		17381375	CTD
21	Ritonavir			OFFSIDES
22	abacavir			OFFSIDES
23	entacapone			OFFSIDES
24	posaconazole			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Pleurisy	27.7%
2	Pneumonia	27.7%
3	Lobar Pneumonia	27.7%
4	Tracheitis	27.7%
5	Pneumonitis	27.7%
6	Common Cold	26.8%
7	Influenza	26.8%
8	Catarrh	26.8%
9	Pleuropneumonia	26.7%
10	Bronchitis	26.1%
11	Gastroenteritis, Transmissible, of Swine	26.1%
12	Pneumonia, Viral	22.6%
13	Laryngitis	22.3%
14	Lung Diseases, Fungal	22.3%
15	Rhinitis	22.3%
16	Lung Abscess	21.8%
17	Tuberculosis, Pulmonary	21.7%
18	Bronchopneumonia	21.7%
19	Sinusitis	20.3%
20	Epiglottitis	20.1%
21	Aspiration Pneumonia	20.1%
22	Bronchiolitis	19.3%
23	Bronchitis, Chronic	18.7%
24	Pharyngitis	16.7%
25	Pneumonia, Lipid	16.5%
26	Pneumonia, Bacterial	16.3%
27	Pertussis	16.2%
28	Orthomyxoviridae Infections	15.4%
29	Picornaviridae Infections	15.4%
30	Reoviridae Infections	15.4%
31	Retroviridae Infections	15.4%
32	Aspergillosis, Allergic Bronchopulmonary	14.7%
33	Bronchial Diseases	14.4%
34	Lung diseases	14.4%
35	Pleural Diseases	14.4%
36	Respiration Disorders	14.4%
37	Thoracic Diseases	14.4%
38	Tracheal Diseases	14.4%
39	Respiratory Distress Syndrome, Adult	13.9%
40	Tracheobronchomegaly	13.8%
41	Hemorrhagic Fever, American	12.6%
42	Lassa Fever	12.6%
43	Asthma	12.5%
44	Hepatitis E	12.3%
45	Tonsillitis	12%
46	Rhinoscleroma	12%
47	Hemorrhagic Fever, Crimean	11.7%
48	Laryngeal Diseases	11.2%
49	Nose Diseases	11.2%
50	Vocal Cord Dysfunction	11.1%
51	Dengue Fever	11.1%
52	Yellow Fever	11.1%
53	Respiratory Distress Syndrome, Newborn	11%
54	Bronchial Fistula	10.9%
55	Lung Neoplasms	10.9%
56	Pleural Neoplasms	10.9%
57	Granuloma, Laryngeal	10.8%
58	Granuloma, Respiratory Tract	10.6%
59	Respiratory Hypersensitivity	10.6%
60	Respiratory Tract Fistula	10.6%
61	Phlebotomus Fever	10.2%
62	Arbovirus Infections	10.2%
63	Rift Valley Fever	10.1%
64	Retropharyngeal Abscess	10%
65	Hemorrhagic Fever with Renal Syndrome	10%
66	Pleural Effusion, Malignant	9.9%
67	Blastomycosis	9.9%
68	Bronchial Neoplasms	9.4%
69	Choanal Atresia	9.2%
70	Laryngocele	9.2%
71	Altitude Sickness	9.1%
72	Atelectasis	9.1%
73	Bronchospasm	9.1%
74	Bronchiectasis	9.1%
75	Chylothorax	9.1%
76	Hydropneumothorax	9.1%
77	Hydrothorax	9.1%
78	Pulmonary Hypertension	9.1%
79	Pneumothorax	9.1%
80	Pulmonary Alveolar Proteinosis	9.1%
81	Pulmonary Edema	9.1%
82	Pulmonary Fibrosis	9.1%
83	Respiratory Insufficiency	9.1%
84	Tracheal Stenosis	9.1%
85	Bronchial Hyperreactivity	9.1%
86	Hamman-Rich syndrome	9.1%
87	Lung Diseases, Interstitial	9.1%
88	Respiratory Depression	9.1%
89	Lung Diseases, Obstructive	9.1%
90	Respiratory Failure	9.1%
91	Idiopathic Pulmonary Fibrosis	9.1%
92	Tracheal Neoplasms	9.1%
93	Porcine Reproductive and Respiratory Syndrome	8.9%
94	Nasopharyngitis	8.6%
95	Enterovirus Infections	8.4%
96	Flavivirus Infections	8.4%
97	Paramyxoviridae Infections	8.4%
98	Cardiovirus Infections	8.4%
99	Rhabdoviridae Infections	8.4%
100	Pneumoconiosis	8.4%
101	Murine Acquired Immunodeficiency Syndrome	8.2%
102	Peritonsillar Abscess	8.2%
103	Hepatitis C	8.1%
104	Laryngospasm	8%
105	Hyaline Membrane Disease	8%
106	Asthma, Exercise-Induced	7.9%
107	Status Asthmaticus	7.9%
108	Multiple Pulmonary Nodules	7.9%
109	Laryngeal neoplasm	7.9%
110	Bronchiolitis Obliterans	7.8%
111	Zika Virus Infection	7.6%
112	Hepatitis, Viral, Human	7.5%
113	Viremia	7.4%
114	Primary Ciliary Dyskinesia	7.1%
115	Granuloma, Lethal Midline	6.9%
116	Laryngeal Edema	6.9%
117	Nose Deformities, Acquired	6.9%
118	Lung Injury	6.9%
119	Hepatopulmonary Syndrome	6.9%
120	Respiratory Aspiration	6.9%
121	Meconium Aspiration Syndrome	6.9%
122	Asthma, Occupational	6.9%
123	Scimitar Syndrome	6.8%
124	Apnea	6.8%
125	Cheyne-Stokes Respiration	6.8%
126	Dyspnea	6.8%
127	Hemothorax	6.8%
128	Hyperventilation	6.8%
129	Mouth Breathing	6.8%
130	Tachypnea	6.8%
131	Pulmonary Embolism	6.8%
132	Pulmonary Eosinophilia	6.7%
133	Radiation Pneumonitis	6.7%
134	Eosinophilic Pneumonia	6.7%
135	Radiation Fibrosis	6.7%
136	Laryngopharyngeal Reflux	6.7%
137	Airway Obstruction	6.7%
138	Choking	6.7%
139	Chronic Obstructive Airway Disease	6.7%
140	Mediastinitis	6.7%
141	Middle Lobe Syndrome	6.7%
142	Acute Lung Injury	6.7%
143	Asbestosis	6.7%
144	Berylliosis	6.7%
145	Silicosis	6.7%
146	Acute Chest Syndrome	6.7%
147	Paranasal Sinus Neoplasms	6.6%
148	Foot-and-Mouth Disease	6.6%
149	Warts	6.5%
150	Opportunistic Infections	6.3%
151	Farmer's Lung	6.1%
152	Simian Acquired Immunodeficiency Syndrome	6.1%
153	Nose Neoplasms	6%
154	West Nile Fever	6%
155	Hepatitis A	6%
156	Hay fever	6%
157	Rhinitis, Allergic, Perennial	6%
158	Hepatitis, Viral, Animal	6%
159	Epstein-Barr Virus Infections	6%
160	Hoarseness	5.9%
161	Asthma, Aspirin-Induced	5.7%
162	Pulmonary Emphysema	5.5%
163	Laryngostenosis	5.5%
164	Nasal Polyps	5.5%
165	Hemoptysis	5.4%
166	Maxillary Sinus Neoplasms	5.4%
167	Kartagener Syndrome	5.3%
168	Herpesviridae Infections	5.1%
169	Polyomavirus Infections	5.1%
170	Mediastinal Cyst	5.1%
171	Pericardial Cyst	5.1%
172	Persistent Fetal Circulation Syndrome	5.1%
173	Thymic Cyst	5.1%
174	Subacute Sclerosing Panencephalitis	5.1%
175	Croup	5%
176	Histiocytosis, Langerhans-Cell	5%
177	Mediastinal Emphysema	5%
178	Rhinitis, Vasomotor	5%
179	Pulmonary Aspergillosis	5%
180	Bronchopulmonary Aspergillosis	5%
181	Hypoventilation	5%
182	Chronic Fatigue Syndrome	5%
183	Sexually Transmitted Diseases	5%
184	Acquired Immunodeficiency Syndrome	5%
185	AIDS related complex	5%
186	Acidosis, Respiratory	5%
187	Alkalosis, Respiratory	5%
188	Sarcoidosis, Pulmonary	5%
189	Sleep Apnea Syndromes	5%
190	Coxsackievirus Infections	5%
191	Rubella	5%
192	Nipah Virus Infection	5%
193	Hydrophobia	5%
194	Pulmonary Infarction	5%
195	Herpangina	4.9%
196	Hepatitis B	4.7%
197	HIV Infections	4.7%
198	Molluscum Contagiosum	4.7%
199	Cystic Fibrosis	4.7%
200	Voice Disorders	4.6%
201	Voice Disturbance	4.6%
202	Epistaxis	4.6%
203	Leukoencephalopathy, Progressive Multifocal	4.3%
204	Condylomata Acuminata	4.2%
205	Bronchopulmonary Dysplasia	4.1%
206	Sleep Apnea, Obstructive	4.1%
207	Sleep Apnea, Central	4.1%
208	Pseudorabies	4.1%
209	Dyspnea, Paroxysmal	4%
210	Respiratory Paralysis	4%
211	Granulomatosis with polyangiitis	4%
212	Laryngomalacia	3.9%
213	Erythema Infectiosum	3.9%
214	Vocal Cord Paralysis	3.9%
215	Hepatitis C, Chronic	3.8%
216	HTLV-I Infections	3.7%
217	Herpes Zoster Ophthalmicus	3.7%
218	AIDS-Related Opportunistic Infections	3.6%
219	Epidermodysplasia Verruciformis	3.6%
220	Transfusion-Related Acute Lung Injury	3.4%
221	Keratitis, Herpetic	3.4%
222	Cytomegalovirus Retinitis	3.4%
223	Exanthema Subitum	3.3%
224	Aphonia	3.3%
225	Dysphonia	3.3%
226	Anti-Glomerular Basement Membrane Disease	3.3%
227	Bronchomalacia	3.3%
228	Tracheomalacia	3.3%
229	Invasive Pulmonary Aspergillosis	3.3%
230	Measles	3.3%
231	Pleurodynia, Epidemic	3.3%
232	Respiratory Syncytial Virus Infections	3.3%
233	Vesicular Stomatitis	3.1%
234	Superinfection	3.1%
235	HIV Seropositivity	3%
236	Cytomegalovirus Infections	2.8%
237	Smallpox	2.8%
238	Varicella Zoster Virus Infection	2.8%
239	Eczema Herpeticum	2.6%
240	Poliomyelitis	2.5%
241	Mumps	2.4%
242	Eosinophilic Granuloma	2.4%
243	Genital Herpes	2.2%
244	Herpes Labialis	2.2%
245	Hepatitis B, Chronic	2.2%
246	HIV Wasting Syndrome	2.1%
247	AIDS Dementia Complex	2.1%
248	AIDS-Associated Nephropathy	2.1%
249	Burkitt Lymphoma	1.9%
250	HIV-Associated Lipodystrophy Syndrome	1.8%
251	Chickenpox	1.7%
252	Bell Palsy	1.4%
253	Infectious Mononucleosis	0.8%
254	Herpes Zoster Oticus	0.6%

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