MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Temporomandibular Joint Disorders

(UMLS:C0039494)

Definition:: A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)
UMLS ID:: C0039494
MeSH ID:: D013705

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.500.607.221.897|C05.550.905|C05.651.243.897

Classification 2:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.320.610.291.897|C07.678

Synonym(s)

Temporomandibular Joint Disorders

TEMPORAL MANDIBULAR JOINT DISORDER

TEMPOROMANDIBULAR JOINT DISEASE

TEMPOROMANDIBULAR JOINT DISORDER

TMJ - Temporomandibular joint disorder

Temporomandibular Joint Diseases

Temporomandibular Joint Disorder

Temporomandibular disorders

Temporomandibular joint disorder

10.

Temporomandibular joint disorder, NOS

11.

Temporomandibular joint disorders

12.

Temporomandibular joint disorders, unspecified

13.

Temporomandibular joint--Diseases

14.

disease (or disorder); temporomandibular joint

15.

disease tmj

16.

disorder joint temporomandibular

17.

disorder temporomandibular

18.

disorders joint temporomandibular

19.

disorders temporomandibular

20.

disorders tmj

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	2057015	CTD
2	Capsaicin	17997062	CTD
3	Cocaine	11889649	CTD
4	Morphine	11731064	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Contracture	33%
2	Arthrogryposis	32.9%
3	Prognathism	30.7%
4	Maxillary Diseases	28%
5	Osteoarthropathy, Secondary Hypertrophic	27%
6	Giant Cell Epulis	25.7%
7	Ischemic contracture	25.4%
8	Retrognathia	24.6%
9	Periarthritis	24.5%
10	Jaw Abnormalities	24.4%
11	Gout	23.5%
12	Metatarsalgia	23.4%
13	Osteoarthritis, Spine	23%
14	Hip Contracture	22.5%
15	Fibromyalgia	21.7%
16	Polymyalgia Rheumatica	21.7%
17	Ankylosing spondylitis	21.2%
18	Arthritis	20.3%
19	Bursitis	20.3%
20	Joint Instability	20.3%
21	Synovitis	20.3%
22	Joint laxity	20.3%
23	Polyarthritis	20.3%
24	Frozen shoulder	20.3%
25	Patellofemoral Pain Syndrome	20.3%
26	Cleft Palate	19.8%
27	Jaw Diseases	19.8%
28	Fasciitis, Plantar	19%
29	Rheumatic Fever	18.9%
30	Arthritis, Psoriatic	18.7%
31	Bone Diseases	18.5%
32	Fasciitis	18.5%
33	Foot Deformities	18.5%
34	Radicular Cyst	18.2%
35	Palatal Neoplasms	18.1%
36	Myofascial Pain Syndromes	18%
37	Rhabdomyolysis	18%
38	Arthritis, Gouty	17.7%
39	Pectus carinatum	17.6%
40	Micrognathism	17.4%
41	Pierre Robin Syndrome	17.4%
42	Hemarthrosis	17.3%
43	Temporomandibular Joint Dysfunction Syndrome	17%
44	Rheumatoid Arthritis	16.9%
45	Juvenile arthritis	16.9%
46	Arthritis, Reactive	16.9%
47	Osteochondritis	16.5%
48	Osteoarthritis, Knee	16.1%
49	Temporomandibular Joint Disorders	16%
50	Cartilage Diseases	15.8%
51	Foot Diseases	15.8%
52	Rheumatism	15.8%
53	Chondromalacia	15.8%
54	Compartment syndromes	15.5%
55	Tendinitis	15.5%
56	Tendinopathy	15.5%
57	Myositis	15.3%
58	Isaacs syndrome	15.3%
59	Myotonic Disorders	15.3%
60	Mouth Diseases	14.9%
61	Tooth Diseases	14.9%
62	Tooth Loss	14.9%
63	Mouth Abnormalities	14.8%
64	Platybasia	14.7%
65	Sacroiliitis	14.4%
66	Rheumatoid Nodule	14%
67	Spondylarthropathies	13.8%
68	Pectus excavatum	13.8%
69	Medial Tibial Stress Syndrome	13.5%
70	Nail-Patella Syndrome	13.5%
71	Sicca Syndrome	13.5%
72	Sjogren's Syndrome	13.5%
73	Mitochondrial Myopathies	13.4%
74	Muscle Cramp	13.3%
75	Eosinophilia-Myalgia Syndrome	13.3%
76	Muscle Rigidity	13.2%
77	Muscle Spasticity	13.2%
78	Cogwheel Rigidity	13.2%
79	Nuchal Rigidity	13.2%
80	Arthralgia	13.2%
81	Polyarthralgia	13.2%
82	Pharyngeal Diseases	13%
83	Facial Hemiatrophy	12.9%
84	Melkersson-Rosenthal Syndrome	12.9%
85	Talipes	12.9%
86	Klippel-Feil Syndrome	12.4%
87	Synostosis	12.4%
88	Felty Syndrome	12.4%
89	Arthritis, Infectious	12.4%
90	Parotid Neoplasms	12.3%
91	Arthritis, Experimental	12.3%
92	Chronic Fatigue Syndrome	12.2%
93	Acrocephalosyndactylia	12.1%
94	Fibrodysplasia Ossificans Progressiva	12.1%
95	Myoglobinuria	12.1%
96	Myositis Ossificans	12.1%
97	Tenosynovitis	12.1%
98	Muscle Weakness	11.9%
99	Musculoskeletal Pain	11.8%
100	Familial Periodic Paralysis	11.7%
101	Alveolar Bone Loss	11.7%
102	Craniosynostosis	11.6%
103	Syndactyly	11.6%
104	Brachycephaly	11.6%
105	Bell Palsy	11.5%
106	Maxillofacial Abnormalities	11.4%
107	Arthropathy	11.3%
108	Gigantism	11.1%
109	Spinal Neoplasms	11.1%
110	Spondylitis	11.1%
111	Rheumatoid Vasculitis	11.1%
112	Dental Enamel Hypoplasia	11.1%
113	Hypodontia	11.1%
114	Macrostomia	11.1%
115	Microstomia	11.1%
116	Salivary Gland Fistula	11.1%
117	Salivary Gland Neoplasms	11.1%
118	Tongue Neoplasms	11.1%
119	Bone Diseases, Developmental	11%
120	Hyperostosis	11%
121	Osteitis	11%
122	Osteitis Deformans	11%
123	Osteochondrosis	11%
124	Spinal Diseases	11%
125	Hip Dislocation	10.9%
126	Shoulder Dislocation	10.9%
127	Hip Dysplasia	10.9%
128	Myopathy	10.7%
129	Gingival Recession	10.7%
130	Parotitis	10.7%
131	Gingival Atrophy	10.7%
132	Myalgia	10.5%
133	Myotonic Dystrophy	10.3%
134	Anterior Compartment Syndrome	10.3%
135	Enthesopathy	10.3%
136	Abdominal Compartment Syndrome	10.3%
137	Congenital clubfoot	10.3%
138	Vertical Talus	10.3%
139	Polymyositis	10.2%
140	Gingival Hemorrhage	10.2%
141	Basal Cell Nevus Syndrome	10%
142	Bruxism	9.9%
143	Burning Mouth Syndrome	9.9%
144	Dental Leakage	9.9%
145	Hypercementosis	9.9%
146	Lip Diseases	9.9%
147	Malocclusion	9.9%
148	Microglossia	9.9%
149	Oral Submucous Fibrosis	9.9%
150	Periodontal Diseases	9.9%
151	Salivary Gland Diseases	9.9%
152	Stomatitis	9.9%
153	Tongue Diseases	9.9%
154	Tooth Crowding	9.9%
155	Tooth Discoloration	9.9%
156	Tooth Demineralization	9.9%
157	Oral Ulcer	9.9%
158	Tooth Ankylosis	9.9%
159	Craniofacial Dysostosis	9.7%
160	Bone Diseases, Endocrine	9.7%
161	Bone Diseases, Infectious	9.5%
162	Bone neoplasms	9.5%
163	Osteopenia	9.5%
164	Bone Resorption	9.4%
165	Tietze's Syndrome	9.4%
166	Limb Deformities, Congenital	9.4%
167	Craniofacial Abnormalities	9.4%
168	Aseptic Necrosis of Bone	9.4%
169	Shoulder Pain	9.3%
170	Poland Syndrome	9.2%
171	Muscular Dystrophy	9%
172	Orbital Myositis	9%
173	Dupuytren Contracture	9%
174	Pyomyositis	8.9%
175	Nasopharyngitis	8.8%
176	Tooth Injuries	8.7%
177	Facial Nerve Diseases	8.5%
178	Tooth Resorption	8.5%
179	Granulomatosis, Orofacial	8.5%
180	Discitis	8.4%
181	Oral candidiasis	8.4%
182	Mouth Neoplasms	8.4%
183	Oral Fistula	8.4%
184	Toothache	8.4%
185	Lichen Planus, Oral	8.4%
186	Gastroschisis	8.2%
187	Nasopharyngeal Neoplasms	8%
188	Myotonia Congenita	7.9%
189	Congenital Hypothyroidism	7.8%
190	Hypokalemic periodic paralysis	7.8%
191	Ainhum	7.5%
192	Bunion	7.5%
193	Cheilitis	7.5%
194	Dental caries	7.5%
195	Dental Plaque	7.5%
196	Dental Pulp Calcification	7.5%
197	Drooling	7.5%
198	Dysostoses	7.5%
199	Gingival Diseases	7.5%
200	Glossitis	7.5%
201	Macroglossia	7.5%
202	Periodontitis	7.5%
203	Pulpitis	7.5%
204	Sialadenitis	7.5%
205	Sialometaplasia, Necrotizing	7.5%
206	Sialorrhea	7.5%
207	Spinal Stenosis	7.5%
208	Spondylosis	7.5%
209	Aphthous Stomatitis	7.5%
210	Tooth Erosion	7.5%
211	Xerostomia	7.5%
212	Intervertebral Disc Degeneration	7.5%
213	Glossoptosis	7.5%
214	Peri-Implantitis	7.5%
215	Pharyngitis	7.5%
216	Tuberculosis, Spinal	7.4%
217	Facial paralysis	7.3%
218	Facial Paresis	7.3%
219	Hemifacial Spasm	7.2%
220	Antley-Bixler Syndrome Phenotype	7.2%
221	Mitochondrial Encephalomyopathies	7.1%
222	Mandibulofacial Dysostosis	6.9%
223	Goldenhar Syndrome	6.8%
224	Welander Distal Myopathy	6.8%
225	Laryngomalacia	6.6%
226	Pharyngeal Neoplasms	6.6%
227	Rubinstein-Taybi Syndrome	6.4%
228	Eosinophilic Granuloma	6.4%
229	Multiple Epiphyseal Dysplasia	6.4%
230	Osteochondrodysplasias	6.4%
231	Tooth Avulsion	6.4%
232	Dental Pulp Necrosis	6.4%
233	Facial Neuralgia	6.4%
234	Osteomyelitis	6.4%
235	Osteoporosis	6.4%
236	Periostitis	6.4%
237	Bone Demineralization, Pathologic	6.4%
238	Post-Traumatic Osteoporosis	6.4%
239	Amelia	6.3%
240	Arachnodactyly	6.3%
241	Dental Fistula	6.3%
242	Ectromelia	6.3%
243	Femur Head Necrosis	6.3%
244	Hemimelia	6.3%
245	Oroantral Fistula	6.3%
246	Phocomelia	6.3%
247	Sirenomelia	6.3%
248	Polydactyly	6.3%
249	Brachydactyly	6.3%
250	Plagiocephaly	6.3%
251	Lower Extremity Deformities, Congenital	6.3%
252	Upper Extremity Deformities, Congenital	6.3%
253	Osteolysis	6.3%
254	Gingivitis	6.3%
255	Glossitis, Benign Migratory	6.3%
256	Pericoronitis	6.3%
257	Aggressive Periodontitis	6.3%
258	Gingival Overgrowth	6.3%
259	Dermatomyositis	6.1%
260	Nasopharyngeal carcinoma	6.1%
261	Muscular Dystrophy, Duchenne	6%
262	Dwarfism	5.8%
263	Chondrodysplasia Punctata	5.7%
264	Enchondromatosis	5.7%
265	Lordosis	5.7%
266	Osteosclerosis	5.7%
267	Spondylolysis	5.7%
268	kyphosis	5.7%
269	Kashin-Beck Disease	5.7%
270	Gingival Hyperplasia	5.7%
271	Gingival Hypertrophy	5.7%
272	Vesicular Stomatitis	5.7%
273	Tonsillitis	5.6%
274	Sleep Bruxism	5.6%
275	Acromegaly	5.5%
276	Joint Tuberculosis	5.5%
277	Tuberculosis, Osteoarticular	5.5%
278	Bone Tuberculosis	5.5%
279	Trigeminal Nerve Disorder	5.3%
280	Behcet Syndrome	5.2%
281	Lemierre Syndrome	5.2%
282	Mobius Syndrome	5%
283	Herpes Zoster Oticus	4.9%
284	Leukoplakia, Oral	4.9%
285	Retropharyngeal Abscess	4.9%
286	Hypopharyngeal Neoplasms	4.9%
287	Hypopharyngeal Cancer	4.9%
288	Rickets	4.9%
289	Bronchomalacia	4.9%
290	Tracheomalacia	4.9%
291	Herpes Labialis	4.9%
292	Microcephaly	4.9%
293	Macrocephaly	4.9%
294	Osteoporosis, Postmenopausal	4.9%
295	Melorheostosis	4.8%
296	Osteopetrosis	4.8%
297	Spondylolisthesis	4.8%
298	Mumps	4.8%
299	Trigeminal Neuralgia	4.8%
300	Pseudohypoparathyroidism	4.4%
301	Facial Nerve Injuries	4.4%
302	Osteogenesis Imperfecta	4.3%
303	Ulcerative stomatitis	4.3%
304	Mastoiditis	4.2%
305	Petrositis	4.2%
306	Peritonsillar Abscess	4.1%
307	Tonsillar Neoplasms	4.1%
308	Noonan Syndrome	4%
309	Toxic Epidermal Necrolysis	4%
310	Stevens-Johnson Syndrome	4%
311	MELAS Syndrome	3.8%
312	Osteomalacia	3.7%
313	Porencephaly	3.7%
314	Marfan Syndrome	3.7%
315	Holoprosencephaly	3.7%
316	Kearns-Sayre syndrome	3.5%
317	Cockayne Syndrome	3.1%
318	Nose Neoplasms	2.9%
319	Renal Osteodystrophy	2.8%
320	Renal rickets	2.8%
321	Familial Hypophosphatemic Rickets	1.6%

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