MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Joint Instability

(UMLS:C0022410)

Definition:: Lack of stability of a joint or joint prosthesis.
UMLS ID:: C0022410
MeSH ID:: D007593

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.521

Synonym(s)

Joint Instability

Decreased stability of joint

Instability of joint

JOINT INSTABILITY

Joint gives way

Joint instability

Joint unstable

Joint unsteady

Unstable joint

10.

instability; joint

11.

joint instability

12.

joint; instability

13.

unstable joint

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Teriparatide	FAERS: 14	US FAERS
2	Ciprofloxacin	FAERS: 13	US FAERS
3	Simvastatin	FAERS: 10	US FAERS
4	Fingolimod Hydrochloride	FAERS: 9	US FAERS
5	Valproic Acid	FAERS: 9	US FAERS
6	tofacitinib	FAERS: 7	US FAERS
7	4-Aminopyridine	FAERS: 4	US FAERS
8	Alendronate	FAERS: 4	US FAERS
9	Dimethyl Fumarate	FAERS: 4 Canada Vigilance: 1	Canada Vigilance US FAERS
10	Lenalidomide	FAERS: 4	US FAERS
11	teriflunomide	FAERS: 4	US FAERS
12	Ezetimibe, Simvastatin Drug Combination	FAERS: 3	US FAERS
13	Fulvestrant	FAERS: 3	US FAERS
14	Moxifloxacin	FAERS: 3	US FAERS
15	Omeprazole	FAERS: 3	OFFSIDES US FAERS
16	Rosuvastatin Calcium	FAERS: 3	US FAERS
17	Triamcinolone	FAERS: 3	US FAERS
18	17 alpha-Hydroxyprogesterone Caproate	FAERS: 2	US FAERS
19	Anastrozole	FAERS: 2	US FAERS
20	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 2	US FAERS
21	Ciprofloxacin	FAERS: 2	US FAERS
22	Glatiramer Acetate	FAERS: 2	US FAERS
23	Methylprednisolone Acetate	FAERS: 2	US FAERS
24	Norgestrel	FAERS: 2	US FAERS
25	NuvaRing	FAERS: 2	US FAERS
26	Pregabalin	FAERS: 2	US FAERS
27	Tamsulosin	FAERS: 2	US FAERS
28	Valproic Acid	FAERS: 2	US FAERS
29	Zoledronic Acid	FAERS: 2	US FAERS
30	ambrisentan	FAERS: 2	US FAERS
31	niraparib	FAERS: 2	US FAERS
32	suvorexant	FAERS: 2	US FAERS
33	telmisartan, hydrochlorothiazide drug combination	FAERS: 2	US FAERS
34	venetoclax	FAERS: 2	US FAERS
35	4-hydroxybutyric acid	FAERS: 1	US FAERS
36	Alprazolam	FAERS: 1	US FAERS
37	Cinacalcet	FAERS: 1	US FAERS
38	Citalopram	FAERS: 1	US FAERS
39	Clozapine	FAERS: 1	US FAERS
40	Copper	FAERS: 1	US FAERS
41	Crizotinib	FAERS: 1	US FAERS
42	Diovan Hct	FAERS: 1	US FAERS
43	Droxidopa	FAERS: 1	US FAERS
44	Duloxetine Hydrochloride	FAERS: 1	US FAERS
45	Finasteride	FAERS: 1	US FAERS
46	Fosamax plus D	FAERS: 1	US FAERS
47	Ibandronic Acid	FAERS: 1	US FAERS
48	Ibandronic Acid	FAERS: 1	US FAERS
49	Imatinib Mesylate	FAERS: 1	US FAERS
50	Letrozole	FAERS: 1	US FAERS
51	MDV 3100	FAERS: 1	US FAERS
52	Metoprolol	FAERS: 1	US FAERS
53	Prednisone	FAERS: 1	US FAERS
54	Sulfasalazine	FAERS: 1	US FAERS
55	Sunitinib	FAERS: 1	US FAERS
56	Thyroxine	FAERS: 1	OFFSIDES US FAERS
57	Topiramate	FAERS: 1	OFFSIDES US FAERS
58	Valproic Acid	FAERS: 1	US FAERS
59	acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide	FAERS: 1	US FAERS
60	apremilast	FAERS: 1	US FAERS
61	fesoterodine	FAERS: 1	US FAERS
62	hydrochlorothiazide, lisinopril drug combination	FAERS: 1	US FAERS
63	ivacaftor	FAERS: 1	US FAERS
64	mirabegron	FAERS: 1	US FAERS
65	pimavanserin	FAERS: 1	US FAERS
66	rofecoxib	FAERS: 1	US FAERS
67	valbenazine	FAERS: 1	US FAERS
68	zolmitriptan	FAERS: 1	US FAERS
69	1 alpha-hydroxyergocalciferol		OFFSIDES
70	Albuterol		OFFSIDES
71	Amlodipine		OFFSIDES
72	Amlodipine		OFFSIDES
73	Aspirin		OFFSIDES
74	Baclofen		OFFSIDES
75	Bortezomib		OFFSIDES
76	Bupivacaine		OFFSIDES
77	Butylscopolammonium Bromide		OFFSIDES
78	Calcium Chloride		OFFSIDES
79	Calcium Citrate		OFFSIDES
80	Calcium Compounds		OFFSIDES
81	Chondroitin Sulfates		OFFSIDES
82	Citalopram		OFFSIDES
83	Dapsone		OFFSIDES
84	Dexamethasone		SIDER
85	Doxepin		OFFSIDES
86	Enalapril	Canada Vigilance: 1	Canada Vigilance
87	Estradiol		OFFSIDES
88	Estrogens, Conjugated (USP)		OFFSIDES
89	Fenofibrate		OFFSIDES
90	Fluconazole		OFFSIDES
91	Ipratropium		OFFSIDES
92	Isosorbide Dinitrate		OFFSIDES
93	Leflunomide		OFFSIDES
94	Losartan		OFFSIDES
95	Magnesium		OFFSIDES
96	Methotrexate		OFFSIDES
97	Mycophenolic Acid		OFFSIDES
98	Pantoprazole		OFFSIDES
99	Prochlorperazine		OFFSIDES
100	Ramipril		OFFSIDES
101	Risedronic Acid		OFFSIDES
102	Sevelamer		OFFSIDES
103	Sevelamer		OFFSIDES
104	Sodium ferric gluconate complex		OFFSIDES
105	Tacrolimus		OFFSIDES
106	Tamsulosin		OFFSIDES
107	Terazosin		OFFSIDES
108	Terbutaline		OFFSIDES
109	Testosterone		OFFSIDES
110	Tetrabenazine		OFFSIDES
111	Triiodothyronine		OFFSIDES
112	Valacyclovir		OFFSIDES
113	Venlafaxine Hydrochloride		OFFSIDES
114	Warfarin		OFFSIDES
115	calcium acetate		OFFSIDES
116	carbidopa, levodopa drug combination		OFFSIDES
117	gadodiamide		OFFSIDES
118	oxybutynin		OFFSIDES
119	rizatriptan		OFFSIDES
120	rizatriptan		OFFSIDES
121	tegaserod		OFFSIDES
122	tegaserod		OFFSIDES
123	zafirlukast		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Arthritis	42.9%
2	Bursitis	42.9%
3	Synovitis	42.9%
4	Polyarthritis	42.9%
5	Frozen shoulder	42.9%
6	Patellofemoral Pain Syndrome	42.9%
7	Periarthritis	40.9%
8	Contracture	38.1%
9	Osteoarthropathy, Secondary Hypertrophic	38.1%
10	Sacroiliitis	31%
11	Ankylosing spondylitis	29.5%
12	Arthrogryposis	28.2%
13	Hemarthrosis	27.9%
14	Metatarsalgia	27.8%
15	Hip Contracture	27.3%
16	Osteoarthritis, Spine	26.7%
17	Gout	24.7%
18	Osteoarthritis, Knee	23.6%
19	Arthritis, Psoriatic	23.5%
20	Bone Diseases	23.1%
21	Fasciitis	23.1%
22	Foot Deformities	23.1%
23	Rheumatic Fever	22.2%
24	Spondylarthropathies	21.5%
25	Arthritis, Reactive	21.5%
26	Arthritis, Infectious	20.9%
27	Arthritis, Experimental	20.5%
28	Temporomandibular Joint Disorders	20.3%
29	Ischemic contracture	20.3%
30	Arthritis, Gouty	19.7%
31	Fasciitis, Plantar	19%
32	Rheumatoid Arthritis	18.1%
33	Juvenile arthritis	18.1%
34	Rheumatoid Nodule	17.5%
35	Nail-Patella Syndrome	16.7%
36	Arthralgia	16.1%
37	Polyarthralgia	16.1%
38	Temporomandibular Joint Dysfunction Syndrome	16%
39	Hip Dislocation	15.8%
40	Jaw Diseases	15.8%
41	Shoulder Dislocation	15.8%
42	Hip Dysplasia	15.8%
43	Cartilage Diseases	15%
44	Foot Diseases	15%
45	Myopathy	15%
46	Rheumatism	15%
47	Chondromalacia	15%
48	Bone Diseases, Developmental	14.3%
49	Hyperostosis	14.3%
50	Myofascial Pain Syndromes	14.3%
51	Osteitis	14.3%
52	Osteitis Deformans	14.3%
53	Osteochondrosis	14.3%
54	Rhabdomyolysis	14.3%
55	Spinal Diseases	14.3%
56	Fibromyalgia	14%
57	Osteochondritis	14%
58	Polymyalgia Rheumatica	14%
59	Felty Syndrome	14%
60	Pectus carinatum	12.6%
61	Platybasia	12.1%
62	Pectus excavatum	12.1%
63	Shoulder Pain	11.8%
64	Rheumatoid Vasculitis	11.6%
65	Klippel-Feil Syndrome	11.1%
66	Synostosis	11.1%
67	Talipes	10.9%
68	Ainhum	10.3%
69	Bunion	10.3%
70	Dysostoses	10.3%
71	Fibrodysplasia Ossificans Progressiva	10.3%
72	Myoglobinuria	10.3%
73	Myositis Ossificans	10.3%
74	Spinal Stenosis	10.3%
75	Spondylosis	10.3%
76	Tenosynovitis	10.3%
77	Intervertebral Disc Degeneration	10.3%
78	Gigantism	10.2%
79	Spinal Neoplasms	10.2%
80	Spondylitis	10.2%
81	Bone Diseases, Endocrine	10%
82	Sicca Syndrome	10%
83	Sjogren's Syndrome	10%
84	Bone Diseases, Infectious	9.5%
85	Bone neoplasms	9.5%
86	Compartment syndromes	9.5%
87	Maxillary Diseases	9.5%
88	Osteopenia	9.5%
89	Tendinitis	9.5%
90	Tendinopathy	9.5%
91	Bone Resorption	9.3%
92	Myositis	9.3%
93	Tietze's Syndrome	9.3%
94	Limb Deformities, Congenital	9.3%
95	Isaacs syndrome	9.3%
96	Craniofacial Abnormalities	9.3%
97	Aseptic Necrosis of Bone	9.3%
98	Myotonic Disorders	9.3%
99	Congenital clubfoot	9.3%
100	Vertical Talus	9.3%
101	Craniofacial Dysostosis	9.2%
102	Craniosynostosis	9.1%
103	Syndactyly	9.1%
104	Brachycephaly	9.1%
105	Chondrodysplasia Punctata	8.5%
106	Enchondromatosis	8.5%
107	Lordosis	8.5%
108	Osteosclerosis	8.5%
109	Spondylolysis	8.5%
110	kyphosis	8.5%
111	Kashin-Beck Disease	8.5%
112	Acrocephalosyndactylia	8.3%
113	Discitis	8.3%
114	Poland Syndrome	7.7%
115	Melorheostosis	7.6%
116	Osteopetrosis	7.6%
117	Spondylolisthesis	7.6%
118	Goldenhar Syndrome	7.1%
119	Medial Tibial Stress Syndrome	7%
120	Multiple Epiphyseal Dysplasia	7%
121	Osteochondrodysplasias	7%
122	Mitochondrial Myopathies	6.9%
123	Muscle Cramp	6.8%
124	Eosinophilia-Myalgia Syndrome	6.8%
125	Gastroschisis	6.8%
126	Anterior Compartment Syndrome	6.8%
127	Osteomyelitis	6.8%
128	Osteoporosis	6.8%
129	Periostitis	6.8%
130	Enthesopathy	6.8%
131	Bone Demineralization, Pathologic	6.8%
132	Post-Traumatic Osteoporosis	6.8%
133	Abdominal Compartment Syndrome	6.8%
134	Muscle Rigidity	6.8%
135	Muscle Spasticity	6.8%
136	Cogwheel Rigidity	6.8%
137	Nuchal Rigidity	6.8%
138	Alveolar Bone Loss	6.7%
139	Amelia	6.7%
140	Arachnodactyly	6.7%
141	Ectromelia	6.7%
142	Femur Head Necrosis	6.7%
143	Hemimelia	6.7%
144	Phocomelia	6.7%
145	Sirenomelia	6.7%
146	Polymyositis	6.7%
147	Polydactyly	6.7%
148	Brachydactyly	6.7%
149	Plagiocephaly	6.7%
150	Lower Extremity Deformities, Congenital	6.7%
151	Upper Extremity Deformities, Congenital	6.7%
152	Osteolysis	6.7%
153	Tuberculosis, Spinal	6.5%
154	Jaw Abnormalities	6.3%
155	Mandibulofacial Dysostosis	6.2%
156	Congenital Hypothyroidism	6.2%
157	Prognathism	6%
158	Chronic Fatigue Syndrome	5.8%
159	Antley-Bixler Syndrome Phenotype	5.8%
160	Osteoporosis, Postmenopausal	5.6%
161	Giant Cell Epulis	5.5%
162	Muscle Weakness	5.5%
163	Dwarfism	5.5%
164	Musculoskeletal Pain	5.4%
165	Familial Periodic Paralysis	5.4%
166	Muscular Dystrophy	5.1%
167	Orbital Myositis	5.1%
168	Dupuytren Contracture	5.1%
169	Pyomyositis	5%
170	Acromegaly	5%
171	Joint Tuberculosis	5%
172	Tuberculosis, Osteoarticular	5%
173	Bone Tuberculosis	5%
174	Palatal Neoplasms	5%
175	Micrognathism	4.9%
176	Pierre Robin Syndrome	4.9%
177	Laryngomalacia	4.7%
178	Rubinstein-Taybi Syndrome	4.6%
179	Myotonic Dystrophy	4.6%
180	Eosinophilic Granuloma	4.5%
181	Myalgia	4.5%
182	Retrognathia	4.3%
183	Osteogenesis Imperfecta	4.3%
184	Welander Distal Myopathy	4.1%
185	Mastoiditis	4.1%
186	Petrositis	4.1%
187	Maxillofacial Abnormalities	4.1%
188	Myotonia Congenita	4%
189	Rickets	4%
190	Bronchomalacia	4%
191	Tracheomalacia	4%
192	Microcephaly	4%
193	Macrocephaly	4%
194	Hypokalemic periodic paralysis	3.9%
195	Basal Cell Nevus Syndrome	3.6%
196	Cleft Palate	3.4%
197	Dermatomyositis	3.4%
198	Pseudohypoparathyroidism	3.3%
199	Muscular Dystrophy, Duchenne	3.3%
200	Mitochondrial Encephalomyopathies	3.3%
201	Osteomalacia	3.3%
202	Porencephaly	3.3%
203	Noonan Syndrome	2.9%
204	Marfan Syndrome	2.6%
205	Holoprosencephaly	2.5%
206	Radicular Cyst	2.4%
207	Cockayne Syndrome	2.4%
208	Nose Neoplasms	2.1%
209	Renal Osteodystrophy	2%
210	Renal rickets	2%
211	MELAS Syndrome	1.6%
212	Kearns-Sayre syndrome	1.5%
213	Familial Hypophosphatemic Rickets	1.1%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237