MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Endolymphatic Hydrops

(UMLS:C0206586)

Definition:: An accumulation of ENDOLYMPH in the inner ear (LABYRINTH) leading to buildup of pressure and distortion of intralabyrinthine structures, such as COCHLEA and SEMICIRCULAR CANALS. It is characterized by SENSORINEURAL HEARING LOSS; TINNITUS; and sometimes VERTIGO.
UMLS ID:: C0206586
MeSH ID:: D018159

Classification:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.218.568.217

Synonym(s)

Endolymphatic Hydrops

Cochlear hydrops

Endolymphatic hydrops

Endolymphatic hydrops syndrome

HYDROPS, COCHLEAR

HYDROPS, ENDOLYMPHATIC

HYDROPS, LABYRINTHINE

Labyrinthine hydrops

cochlear hydrops

10.

endolymphatic hydrops

11.

endolymphatic; hydrops

12.

hydrops; endolymphatic

13.

labyrinthine hydrops

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Venlafaxine Hydrochloride	FAERS: 4		US FAERS
2	Tadalafil	FAERS: 2		US FAERS
3	Zoledronic Acid	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
4	Iloprost	FAERS: 1		US FAERS
5	Losartan	FAERS: 1		US FAERS
6	Methylphenidate	FAERS: 1		US FAERS
7	Norgestrel	FAERS: 1		OFFSIDES US FAERS
8	Thyroxine	FAERS: 1		US FAERS
9	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
10	rofecoxib	FAERS: 1		OFFSIDES US FAERS
11	Dimethyl Fumarate	Canada Vigilance: 1		Canada Vigilance
12	Dimethyl Sulfoxide		20641076	CTD
13	Mefloquine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cochlear Diseases	46.7%
2	Vestibular Diseases	46.7%
3	Labyrinthitis	44.4%
4	Otosclerosis	31%
5	Tympanosclerosis	31%
6	Tympanic Membrane Perforation	22%
7	Otomycosis	20.9%
8	Congenital Microtia	20.9%
9	Ear Neoplasms	20.5%
10	Otitis Externa	20%
11	Otitis Media	20%
12	Vertigo	17.6%
13	Dysacusis	15.1%
14	Otitis Media with Effusion	14.8%
15	Vestibulocochlear Nerve Diseases	13.6%
16	Laryngeal Diseases	12.8%
17	Nose Diseases	12.8%
18	Pharyngeal Diseases	12.8%
19	Herpes Zoster Oticus	12%
20	Vestibular Neuronitis	9.9%
21	Hyperacusis	9.8%
22	Tinnitus	9.8%
23	Phonophobia	9.8%
24	Hearing Loss	9.8%
25	Pharyngeal Neoplasms	8.3%
26	Mastoiditis	7.3%
27	Petrositis	7.3%
28	Deafness	7.2%
29	Hearing Loss, Sudden	7.2%
30	Hearing Loss, Bilateral	7.2%
31	Hearing Loss, High-Frequency	7.2%
32	Hearing Loss, Mixed Conductive-Sensorineural	7.2%
33	Hearing Loss, Unilateral	7.2%
34	Complete Hearing Loss	7.2%
35	Deaf Mutism	7.2%
36	Primary Ciliary Dyskinesia	7.2%
37	Granuloma, Lethal Midline	7%
38	Laryngeal Edema	7%
39	Nose Deformities, Acquired	7%
40	Laryngeal neoplasm	6.9%
41	Deglutition Disorders	6.8%
42	Nasopharyngeal Neoplasms	5.7%
43	Hypopharyngeal Neoplasms	5.3%
44	Hypopharyngeal Cancer	5.3%
45	Laryngitis	5.3%
46	Pharyngitis	5.3%
47	Rhinitis	5.3%
48	Vocal Cord Dysfunction	5.3%
49	Laryngostenosis	5.2%
50	Nasal Polyps	5.2%
51	Nose Neoplasms	5.1%
52	Paranasal Sinus Neoplasms	5%
53	Acoustic Neuroma	4.9%
54	Croup	4.4%
55	Nasopharyngitis	4.4%
56	Rhinitis, Vasomotor	4.4%
57	Auditory Perceptual Disorders	4.2%
58	Choanal Atresia	4.2%
59	Voice Disorders	4.2%
60	Voice Disturbance	4.2%
61	Laryngocele	4.2%
62	Epistaxis	4.1%
63	Tonsillar Neoplasms	3.9%
64	Maxillary Sinus Neoplasms	3.6%
65	Nasopharyngeal carcinoma	3.6%
66	Laryngomalacia	3.4%
67	Granuloma, Laryngeal	3.4%
68	Sinusitis	3.4%
69	Vocal Cord Paralysis	3.4%
70	Laryngospasm	3.3%
71	Tonsillitis	3.3%
72	Lemierre Syndrome	2.8%
73	Aphonia	2.6%
74	Retropharyngeal Abscess	2.6%
75	Dysphonia	2.6%
76	Rhinoscleroma	2.5%
77	Hay fever	2%
78	Rhinitis, Allergic, Perennial	2%
79	Peritonsillar Abscess	1.9%
80	Hoarseness	1.9%
81	Kartagener Syndrome	1.5%

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