MetaADEDB 2.0 @ LMMD
Imiquimod
(DOUYETYNHWVLEO-UHFFFAOYSA-N)
Structure
SMILES
CC(Cn1cnc2c1c1ccccc1nc2N)C
Type(s)
Approved; Investigational
ATC code(s)
D06BB10
Molecular Formula:
C14H16N4
Molecular Weight:
240.304
Log P:
3.4039
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
1
TPSA:
56.73
CAS Number(s):
9050-31-1; 99011-02-6
Synonym(s)
1.
Imiquimod
2.
1-Isobutyl-1H-imidazo(4,5-c)quinolin-4-amine
3.
Aldara
4.
R 837
5.
R-837
6.
S 26308
7.
S-26308
8.
Zyclara
9.
R837
External Link(s)
MeSHD000077271
PubChem Compound57469
BindingDB50240849
ChEBI36704
CHEMBLCHEMBL1282
DrugBankDB00724
DrugCentral1429
IUPHAR/BPS Guide to PHARMACOLOGY5003
KEGGdr:D02500
Therapeutic Target DatabaseD06CTE
ZINC19632912
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1FatigueFAERS: 86
Canada Vigilance: 8
31111189CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
2Application site erythemaFAERS: 84
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
3ErythemaFAERS: 74
Canada Vigilance: 2
25965695
28003376
31111189
CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
4HeadacheFAERS: 62
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
5ScabFAERS: 53
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
6Application site painFAERS: 52
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
7PainFAERS: 50
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
8NauseaFAERS: 48
Canada Vigilance: 5
31111189CTD
SIDER
Canada Vigilance
US FAERS
9MalaiseFAERS: 38
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
10MyalgiaFAERS: 38
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
11Drug ineffectiveFAERS: 37
Canada Vigilance: 5
Canada Vigilance
US FAERS
12DizzinessFAERS: 36
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
13PruritusFAERS: 36
Canada Vigilance: 1
31111189CTD
SIDER
Canada Vigilance
US FAERS
14LymphadenopathyFAERS: 35
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
15AstheniaFAERS: 34
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
16Back PainFAERS: 33SIDER
US FAERS
17Product use in unapproved indicationFAERS: 33US FAERS
18Application site scabFAERS: 30OFFSIDES
SIDER
US FAERS
19Application site ulcerFAERS: 29
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
20InflammationFAERS: 2926149470CTD
SIDER
US FAERS
21Application site reactionFAERS: 27OFFSIDES
SIDER
US FAERS
22Application site irritationFAERS: 26OFFSIDES
SIDER
US FAERS
23ArthralgiaFAERS: 26
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
24Weight decreasedFAERS: 25
Canada Vigilance: 3
Canada Vigilance
US FAERS
25ChillsFAERS: 23
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
26Application site inflammationFAERS: 22
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
27Burning sensationFAERS: 19
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
28Inappropriate schedule of drug administrationFAERS: 18OFFSIDES
US FAERS
29Application site vesiclesFAERS: 16OFFSIDES
SIDER
US FAERS
30Erythema MultiformeFAERS: 16OFFSIDES
SIDER
US FAERS
31Lip swellingFAERS: 16US FAERS
32PalpitationsFAERS: 15
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
33Skin UlcerFAERS: 15SIDER
US FAERS
34SwellingFAERS: 15
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
35Application site swellingFAERS: 14
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
36Eye irritationFAERS: 14
Canada Vigilance: 1
Canada Vigilance
US FAERS
37Feeling abnormalFAERS: 14SIDER
US FAERS
38Skin irritationFAERS: 14US FAERS
39VomitingFAERS: 14
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
40Application site pruritusFAERS: 13
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
41Chest PainFAERS: 13
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
42Application site dischargeFAERS: 12OFFSIDES
SIDER
US FAERS
43Application site erosionFAERS: 12OFFSIDES
SIDER
US FAERS
44Drug ineffective for unapproved indicationFAERS: 12
Canada Vigilance: 1
Canada Vigilance
US FAERS
45Eye painFAERS: 12
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
46Oropharyngeal painFAERS: 12
Canada Vigilance: 1
Canada Vigilance
US FAERS
47PsoriasisFAERS: 1226149470CTD
OFFSIDES
SIDER
US FAERS
48Dry skinFAERS: 11US FAERS
49General physical health deteriorationFAERS: 11US FAERS
50Product use issueFAERS: 11US FAERS
51Skin lesionFAERS: 11
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
52UrticariaFAERS: 11SIDER
US FAERS
53AlopeciaFAERS: 10
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
54DehydrationFAERS: 10US FAERS
55Rash erythematousFAERS: 10SIDER
US FAERS
56Skin ErosionFAERS: 10US FAERS
57VitiligoFAERS: 10US FAERS
58Accidental exposure to productFAERS: 9US FAERS
59Application site scarFAERS: 9SIDER
US FAERS
60Dermoid CystFAERS: 9US FAERS
61Disease ProgressionFAERS: 9US FAERS
62DysuriaFAERS: 9OFFSIDES
SIDER
US FAERS
63Impaired work abilityFAERS: 9
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
64InfluenzaFAERS: 9SIDER
US FAERS
65LethargyFAERS: 9SIDER
US FAERS
66Myocardial InfarctionFAERS: 9SIDER
US FAERS
67TinnitusFAERS: 9OFFSIDES
SIDER
US FAERS
68AgitationFAERS: 8SIDER
US FAERS
69Basal cell carcinomaFAERS: 8OFFSIDES
SIDER
US FAERS
70DermatitisFAERS: 828003376CTD
SIDER
US FAERS
71EczemaFAERS: 8OFFSIDES
SIDER
US FAERS
72Lupus-like syndromeFAERS: 8US FAERS
73Oral painFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
74OverdoseFAERS: 8
Canada Vigilance: 1
Canada Vigilance
US FAERS
75Skin reactionFAERS: 8US FAERS
76Stevens-Johnson SyndromeFAERS: 8OFFSIDES
SIDER
US FAERS
77AcneFAERS: 7US FAERS
78Activities of daily living impairedFAERS: 7US FAERS
79AnxietyFAERS: 7
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
80Application site drynessFAERS: 7SIDER
US FAERS
81CellulitisFAERS: 7US FAERS
82Facial PainFAERS: 7US FAERS
83HypotensionFAERS: 731111189CTD
US FAERS
84LeukopeniaFAERS: 7US FAERS
85Musculoskeletal stiffnessFAERS: 7US FAERS
86NasopharyngitisFAERS: 7US FAERS
87SyncopeFAERS: 7SIDER
US FAERS
88TremorFAERS: 7
Canada Vigilance: 3
Canada Vigilance
US FAERS
89Wrong technique in drug usage processFAERS: 7OFFSIDES
US FAERS
90Abdominal PainFAERS: 6SIDER
US FAERS
91AnorexiaFAERS: 6SIDER
US FAERS
92Application site exfoliationFAERS: 6OFFSIDES
SIDER
US FAERS
93Atrial FibrillationFAERS: 6SIDER
US FAERS
94DeliriumFAERS: 6US FAERS
95DementiaFAERS: 6US FAERS
96Disease recurrenceFAERS: 6US FAERS
97Drug administered to patient of inappropriate ageFAERS: 6US FAERS
98Genital erythemaFAERS: 6OFFSIDES
US FAERS
99HypersensitivityFAERS: 6SIDER
US FAERS
100InfectionFAERS: 6SIDER
US FAERS
101No adverse eventFAERS: 6US FAERS
102PurulenceFAERS: 6US FAERS
103ThrombocytopeniaFAERS: 6US FAERS
104UlcerFAERS: 6SIDER
US FAERS
105Visual ImpairmentFAERS: 6
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
106AbasiaFAERS: 5US FAERS
107Application site infectionFAERS: 5OFFSIDES
US FAERS
108Blood glucose increasedFAERS: 5SIDER
US FAERS
109DiscomfortFAERS: 5SIDER
US FAERS
110Drug administration errorFAERS: 5US FAERS
111DysgeusiaFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
112Expired product administeredFAERS: 5US FAERS
113Incorrect dose administeredFAERS: 5US FAERS
114Lichen PlanusFAERS: 5OFFSIDES
US FAERS
115Medication ErrorFAERS: 5US FAERS
116Multiple SclerosisFAERS: 5OFFSIDES
SIDER
US FAERS
117Pain of skinFAERS: 5US FAERS
118PapuleFAERS: 5SIDER
US FAERS
119Peripheral swellingFAERS: 5US FAERS
120PneumoniaFAERS: 5US FAERS
121StomatitisFAERS: 5US FAERS
122Supraventricular tachycardiaFAERS: 5OFFSIDES
SIDER
US FAERS
123Thermal burnFAERS: 5US FAERS
124Unevaluable eventFAERS: 5US FAERS
125VertigoFAERS: 5US FAERS
126White blood cell count decreasedFAERS: 5SIDER
US FAERS
127Actinic keratosisFAERS: 4OFFSIDES
SIDER
US FAERS
128Aphthous StomatitisFAERS: 4US FAERS
129ArthritisFAERS: 4
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
130BlindnessFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
131CheilitisFAERS: 4SIDER
US FAERS
132Chest discomfortFAERS: 4US FAERS
133Chronic papillomatous dermatitisFAERS: 4US FAERS
134ColitisFAERS: 4US FAERS
135CryingFAERS: 4SIDER
US FAERS
136DiplopiaFAERS: 4US FAERS
137Drug effect incompleteFAERS: 4US FAERS
138Drug exposure during pregnancyFAERS: 4OFFSIDES
US FAERS
139Genital painFAERS: 4
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
140Incorrect drug administration durationFAERS: 4US FAERS
141LymphomaFAERS: 4OFFSIDES
SIDER
US FAERS
142Malignant neoplasm progressionFAERS: 4US FAERS
143Musculoskeletal PainFAERS: 4US FAERS
144Neck PainFAERS: 4US FAERS
145NecrosisFAERS: 4US FAERS
146Nerve injuryFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
147Open woundFAERS: 4US FAERS
148Optic NeuritisFAERS: 4OFFSIDES
US FAERS
149Pharyngolaryngeal PainFAERS: 4SIDER
US FAERS
150Product administered at inappropriate siteFAERS: 4US FAERS
151Product quality issueFAERS: 4US FAERS
152Pulmonary EmbolismFAERS: 4US FAERS
153Secretion dischargeFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
154Skin necrosisFAERS: 4US FAERS
155SomnolenceFAERS: 4SIDER
US FAERS
156Squamous cell carcinomaFAERS: 4SIDER
US FAERS
157Therapy non-responderFAERS: 4US FAERS
158ToothacheFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
159Accidental exposureFAERS: 3OFFSIDES
US FAERS
160Adverse eventFAERS: 3US FAERS
161AmnesiaFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
162Application site rashFAERS: 3SIDER
US FAERS
163Autoimmune thyroiditisFAERS: 3US FAERS
164Blood sodium decreasedFAERS: 3US FAERS
165Bone painFAERS: 3
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
166BronchitisFAERS: 3SIDER
US FAERS
167Drug administered at inappropriate siteFAERS: 3US FAERS
168Drug dose omissionFAERS: 3US FAERS
169Drug effective for unapproved indicationFAERS: 3US FAERS
170Duodenal perforationFAERS: 3OFFSIDES
US FAERS
171DysphoniaFAERS: 3OFFSIDES
US FAERS
172Erythrodermic psoriasisFAERS: 3US FAERS
173Exfoliative rashFAERS: 3OFFSIDES
US FAERS
174FlatulenceFAERS: 3US FAERS
175FlushingFAERS: 3SIDER
US FAERS
176Genital burning sensationFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
177HyperkeratosisFAERS: 3SIDER
US FAERS
178LeukocytosisFAERS: 3US FAERS
179Lip exfoliationFAERS: 3US FAERS
180Local reactionFAERS: 3OFFSIDES
SIDER
US FAERS
181Mycosis FungoidesFAERS: 3US FAERS
182Nasal discomfortFAERS: 3US FAERS
183Night sweatsFAERS: 3US FAERS
184PancreatitisFAERS: 3US FAERS
185PemphigusFAERS: 3OFFSIDES
US FAERS
186Pharmaceutical product complaintFAERS: 3US FAERS
187Product packaging quantity issueFAERS: 3US FAERS
188Product substitution issueFAERS: 3US FAERS
189Punctate keratitisFAERS: 3US FAERS
190SepsisFAERS: 3US FAERS
191SinusitisFAERS: 3OFFSIDES
SIDER
US FAERS
192TachycardiaFAERS: 3SIDER
US FAERS
193Therapeutic response unexpectedFAERS: 3OFFSIDES
US FAERS
194Toxic Epidermal NecrolysisFAERS: 3US FAERS
195Urinary RetentionFAERS: 3SIDER
US FAERS
196Wrong technique in product usage processFAERS: 3US FAERS
197treatment failureFAERS: 3US FAERS
198Abdominal discomfortFAERS: 2OFFSIDES
US FAERS
199AbscessFAERS: 2US FAERS
200Acute Coronary SyndromeFAERS: 2SIDER
US FAERS
201Acute kidney injuryFAERS: 2US FAERS
202Alanine Aminotransferase IncreasedFAERS: 2US FAERS
203Aortic valve calcificationFAERS: 2US FAERS
204Application site hypersensitivityFAERS: 2US FAERS
205Application site necrosisFAERS: 2OFFSIDES
US FAERS
206Application site papulesFAERS: 2SIDER
US FAERS
207Application site warmthFAERS: 2SIDER
US FAERS
208Aspartate Aminotransferase IncreasedFAERS: 2US FAERS
209Autoimmune hepatitisFAERS: 2US FAERS
210BedriddenFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
211Benign Prostatic HyperplasiaFAERS: 2US FAERS
212BlepharospasmFAERS: 2OFFSIDES
US FAERS
213Blood count abnormalFAERS: 2US FAERS
214Blood creatine phosphokinase increasedFAERS: 2US FAERS
215Blood immunoglobulin M increasedFAERS: 2US FAERS
216Blood urine presentFAERS: 2US FAERS
217BradycardiaFAERS: 2US FAERS
218CandidiasisFAERS: 2US FAERS
219Cerebrovascular accidentFAERS: 2SIDER
US FAERS
220Clostridium difficile colitisFAERS: 2US FAERS
221Completed SuicideFAERS: 2SIDER
US FAERS
222ConjunctivitisFAERS: 2SIDER
US FAERS
223ConstipationFAERS: 2US FAERS
224Corneal erosionFAERS: 2US FAERS
225CystitisFAERS: 2US FAERS
226DeafnessFAERS: 2US FAERS
227Depressed moodFAERS: 2US FAERS
228DisorientationFAERS: 2US FAERS
229Drug prescribing errorFAERS: 2OFFSIDES
US FAERS
230DysphemiaFAERS: 2US FAERS
231EctropionFAERS: 2US FAERS
232EpistaxisFAERS: 2US FAERS
233Eye InfectionFAERS: 2SIDER
US FAERS
234Eye inflammationFAERS: 2US FAERS
235Eye ulcerFAERS: 2US FAERS
236Gastrointestinal PainFAERS: 2SIDER
US FAERS
237HepatitisFAERS: 2US FAERS
238HypophagiaFAERS: 2US FAERS
239Inappropriate schedule of product administrationFAERS: 2US FAERS
240Incorrect route of drug administrationFAERS: 2US FAERS
241Incorrect route of product administrationFAERS: 2US FAERS
242Increased upper airway secretionFAERS: 2OFFSIDES
US FAERS
243Intentional product misuseFAERS: 2US FAERS
244Intercepted drug dispensing errorFAERS: 2US FAERS
245LacerationFAERS: 2US FAERS
246Limb discomfortFAERS: 2US FAERS
247Lip erosionFAERS: 2OFFSIDES
US FAERS
248Lip neoplasm malignant stage unspecifiedFAERS: 2US FAERS
249Localised skin reactionFAERS: 2OFFSIDES
US FAERS
250Malignant melanoma in situFAERS: 2US FAERS
251NeuropathyFAERS: 2US FAERS
252Neuropsychiatric syndromeFAERS: 2US FAERS
253PancytopeniaFAERS: 2SIDER
US FAERS
254ParesisFAERS: 2SIDER
US FAERS
255Penile erythemaFAERS: 2US FAERS
256PoisoningFAERS: 2US FAERS
257Polymyalgia RheumaticaFAERS: 2US FAERS
258Precancerous skin lesionFAERS: 2US FAERS
259Product physical consistency issueFAERS: 2US FAERS
260Renal painFAERS: 2US FAERS
261Retinal Vein OcclusionFAERS: 2US FAERS
262RetinitisFAERS: 2US FAERS
263RosaceaFAERS: 2US FAERS
264Sinus headacheFAERS: 2US FAERS
265Skin PapillomaFAERS: 2SIDER
US FAERS
266SplenomegalyFAERS: 226149470
28003376
CTD
US FAERS
267Squamous cell carcinoma of skinFAERS: 2US FAERS
268Sudden deathFAERS: 2US FAERS
269Temperature intoleranceFAERS: 2US FAERS
270Testis discomfortFAERS: 2OFFSIDES
US FAERS
271ThirstFAERS: 2US FAERS
272Thymus enlargementFAERS: 2US FAERS
273Tongue blisteringFAERS: 2US FAERS
274Trigeminal NeuralgiaFAERS: 2US FAERS
275Unresponsive to stimuliFAERS: 2US FAERS
276Vaginal DischargeFAERS: 2US FAERS
277Vaginal burning sensationFAERS: 2OFFSIDES
US FAERS
278Wound InfectionFAERS: 2US FAERS
279Wound dehiscenceFAERS: 2OFFSIDES
US FAERS
280furuncleFAERS: 2US FAERS
281muscle injuryFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
282nervous system disorderFAERS: 2SIDER
US FAERS
283AcantholysisFAERS: 1US FAERS
284AcanthosisFAERS: 1US FAERS
285Accidental overdoseFAERS: 1US FAERS
286Administration site necrosisFAERS: 1US FAERS
287Administration site swellingFAERS: 1US FAERS
288Administration site ulcerFAERS: 1US FAERS
289Administration site warmthFAERS: 1US FAERS
290AgeusiaFAERS: 1US FAERS
291Altered state of consciousnessFAERS: 1US FAERS
292Anal discomfortFAERS: 1US FAERS
293AngerFAERS: 1OFFSIDES
US FAERS
294AngioedemaFAERS: 1SIDER
US FAERS
295Anorectal discomfortFAERS: 1SIDER
US FAERS
296AnosmiaFAERS: 1US FAERS
297ApathyFAERS: 1OFFSIDES
US FAERS
298AphagiaFAERS: 1US FAERS
299AphasiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
300AphoniaFAERS: 1US FAERS
301Apparent deathFAERS: 1US FAERS
302Application site burnFAERS: 1
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
303Application site discomfortFAERS: 1US FAERS
304Application site excoriationFAERS: 1SIDER
US FAERS
305Application site indurationFAERS: 1US FAERS
306Application site lymphadenopathyFAERS: 1US FAERS
307Application site massFAERS: 1US FAERS
308Application site plaqueFAERS: 1US FAERS
309Application site woundFAERS: 1US FAERS
310ArteritisFAERS: 1US FAERS
311ArthropathyFAERS: 1US FAERS
312ArthroscopyFAERS: 1US FAERS
313Auricular swellingFAERS: 1US FAERS
314BalanitisFAERS: 1US FAERS
315Bladder painFAERS: 1US FAERS
316Blood glucagon increasedFAERS: 1OFFSIDES
US FAERS
317Blood immunoglobulin G increasedFAERS: 1US FAERS
318Blood potassium decreasedFAERS: 1US FAERS
319Blood thyroid stimulating hormone increasedFAERS: 1US FAERS
320Body temperature fluctuationFAERS: 1US FAERS
321Bowen's DiseaseFAERS: 111207687CTD
US FAERS
322Breech PresentationFAERS: 1US FAERS
323CD4 lymphocytes increasedFAERS: 1US FAERS
324CD4/CD8 ratio increasedFAERS: 1US FAERS
325Capillary Leak SyndromeFAERS: 1SIDER
US FAERS
326Carcinoma in situ of penisFAERS: 1US FAERS
327Carotid artery occlusionFAERS: 1US FAERS
328Carpal Tunnel SyndromeFAERS: 1US FAERS
329CataractFAERS: 1US FAERS
330Caustic injuryFAERS: 1US FAERS
331Central nervous system lesionFAERS: 1US FAERS
332Cerebral congestionFAERS: 1US FAERS
333Cervix carcinomaFAERS: 1US FAERS
334Chemical injuryFAERS: 1US FAERS
335Clostridium colitisFAERS: 1US FAERS
336Cold sweatFAERS: 1US FAERS
337Colon adenomaFAERS: 1US FAERS
338Corneal OpacityFAERS: 1US FAERS
339Deafness NeurosensoryFAERS: 1US FAERS
340Depressed Level of ConsciousnessFAERS: 1US FAERS
341DermatomyositisFAERS: 1OFFSIDES
US FAERS
342Device dislocationFAERS: 1US FAERS
343Diabetes mellitus inadequate controlFAERS: 1US FAERS
344Drain site complicationFAERS: 1US FAERS
345Drug dispensing errorFAERS: 1US FAERS
346Drug resistanceFAERS: 1US FAERS
347Drug toxicityFAERS: 1US FAERS
348DyspepsiaFAERS: 1
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
349Ejection Fraction DecreasedFAERS: 1US FAERS
350Electrocardiogram abnormalFAERS: 1US FAERS
351Emotional disorderFAERS: 1US FAERS
352Endometrial hypertrophyFAERS: 1US FAERS
353Enterococcal infectionFAERS: 1US FAERS
354EnterocolitisFAERS: 1US FAERS
355EpilepsyFAERS: 1US FAERS
356Erythema NodosumFAERS: 1US FAERS
357ExophthalmosFAERS: 1US FAERS
358Expired drug administeredFAERS: 1US FAERS
359Extra dose administeredFAERS: 1US FAERS
360Eye symptomFAERS: 1US FAERS
361Eyelash changesFAERS: 1US FAERS
362Facial ParesisFAERS: 1US FAERS
363False positive investigation resultFAERS: 1US FAERS
364Feeling ColdFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
365Feelings of worthlessnessFAERS: 1US FAERS
366Flank PainFAERS: 1US FAERS
367Food AllergyFAERS: 1US FAERS
368Food PoisoningFAERS: 1US FAERS
369Gait inabilityFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
370GammopathyFAERS: 1US FAERS
371Gastric pH decreasedFAERS: 1US FAERS
372Gastrointestinal inflammationFAERS: 1US FAERS
373General physical condition abnormalFAERS: 1US FAERS
374Genital erosionFAERS: 1US FAERS
375Genital swellingFAERS: 1US FAERS
376GlaucomaFAERS: 1US FAERS
377Grip strength decreasedFAERS: 1US FAERS
378Head discomfortFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
379Hearing disabilityFAERS: 1US FAERS
380HepatosplenomegalyFAERS: 1US FAERS
381HoarsenessFAERS: 1OFFSIDES
US FAERS
382HyperacusisFAERS: 1US FAERS
383HyperthyroidismFAERS: 1US FAERS
384Hypoaesthesia facialFAERS: 1OFFSIDES
US FAERS
385HypoventilationFAERS: 1US FAERS
386Immunoglobulins abnormalFAERS: 1US FAERS
387ImmunosuppressionFAERS: 1US FAERS
388Increased bronchial secretionFAERS: 1US FAERS
389Increased insulin requirementFAERS: 1US FAERS
390IndurationFAERS: 1SIDER
US FAERS
391Instillation site dischargeFAERS: 1US FAERS
392Instillation site erosionFAERS: 1US FAERS
393Instillation site scabFAERS: 1US FAERS
394Intestinal cystFAERS: 1US FAERS
395Intracranial AneurysmFAERS: 1US FAERS
396Iris exfoliationFAERS: 1US FAERS
397IritisFAERS: 1OFFSIDES
US FAERS
398Joint stiffnessFAERS: 1US FAERS
399Joint swellingFAERS: 1US FAERS
400KeratitisFAERS: 1US FAERS
401KetoacidosisFAERS: 1US FAERS
402Lip InfectionFAERS: 1US FAERS
403Lip erythemaFAERS: 1US FAERS
404Lower respiratory tract infectionFAERS: 1US FAERS
405LymphadenitisFAERS: 1US FAERS
406Lymphocytic infiltrationFAERS: 1US FAERS
407MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
408MalabsorptionFAERS: 1US FAERS
409Mantle cell lymphomaFAERS: 1US FAERS
410Memory impairmentFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
411Meniscus injuryFAERS: 1US FAERS
412Mental impairmentFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
413Mental status changesFAERS: 1US FAERS
414Middle insomniaFAERS: 1US FAERS
415Migraine with AuraFAERS: 1US FAERS
416Monocyte percentage increasedFAERS: 1US FAERS
417Multiple Chemical SensitivityFAERS: 1US FAERS
418Muscle enzyme increasedFAERS: 1US FAERS
419MydriasisFAERS: 1US FAERS
420Nasal mucosal disorderFAERS: 1US FAERS
421NephrolithiasisFAERS: 1US FAERS
422Neurological decompensationFAERS: 1US FAERS
423NeutropeniaFAERS: 1US FAERS
424Nodular melanomaFAERS: 1US FAERS
425Noninfective encephalitisFAERS: 1US FAERS
426Ocular discomfortFAERS: 1US FAERS
427ParakeratosisFAERS: 1US FAERS
428Pelvic PainFAERS: 1US FAERS
429Penile InfectionFAERS: 1US FAERS
430Penile curvatureFAERS: 1US FAERS
431Penile swellingFAERS: 1US FAERS
432PeriodontitisFAERS: 1US FAERS
433Periorbital disorderFAERS: 1US FAERS
434PeritonitisFAERS: 1US FAERS
435Perivascular dermatitisFAERS: 1US FAERS
436Pityriasis Rubra PilarisFAERS: 1US FAERS
437PleurisyFAERS: 1US FAERS
438PneumonitisFAERS: 1US FAERS
439PneumothoraxFAERS: 1OFFSIDES
US FAERS
440PolymyositisFAERS: 1US FAERS
441Poor quality sleepFAERS: 1US FAERS
442Post inflammatory pigmentation changeFAERS: 1US FAERS
443Post procedural complicationFAERS: 1US FAERS
444PregnancyFAERS: 1SIDER
US FAERS
445Prescription drug used without a prescriptionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
446PresyncopeFAERS: 1US FAERS
447Product expiration date issueFAERS: 1US FAERS
448Product identification number issueFAERS: 1US FAERS
449Product label confusionFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
450Product lot number issueFAERS: 1US FAERS
451Product physical issueFAERS: 1US FAERS
452Product prescribing errorFAERS: 1US FAERS
453Pruritus AniFAERS: 1US FAERS
454Pulmonary congestionFAERS: 1SIDER
US FAERS
455Pulmonary thrombosisFAERS: 1US FAERS
456PurpuraFAERS: 1SIDER
US FAERS
457Pustular psoriasisFAERS: 1US FAERS
458PyodermaFAERS: 1US FAERS
459Quality of life decreasedFAERS: 1US FAERS
460Renal ColicFAERS: 1US FAERS
461Renal cystFAERS: 1US FAERS
462Retinal DetachmentFAERS: 1US FAERS
463RhabdomyolysisFAERS: 1US FAERS
464Rheumatic disorderFAERS: 1US FAERS
465Rheumatoid ArthritisFAERS: 1US FAERS
466RhinalgiaFAERS: 1US FAERS
467SarcomaFAERS: 1US FAERS
468ScleritisFAERS: 1US FAERS
469Scrotal InfectionFAERS: 1US FAERS
470Scrotal erythemaFAERS: 1SIDER
US FAERS
471Septic ShockFAERS: 1US FAERS
472Sinus painFAERS: 1US FAERS
473Skin IndurationFAERS: 1US FAERS
474Skin WrinklingFAERS: 1US FAERS
475Skin hypertrophyFAERS: 1US FAERS
476Skin tightnessFAERS: 1US FAERS
477Soft tissue necrosisFAERS: 1US FAERS
478StillbirthFAERS: 1US FAERS
479SunburnFAERS: 1US FAERS
480SyphilisFAERS: 1US FAERS
481Therapeutic product ineffectiveFAERS: 1OFFSIDES
US FAERS
482Therapy cessationFAERS: 1US FAERS
483Throat irritationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
484ThrombosisFAERS: 1US FAERS
485ThyroiditisFAERS: 1SIDER
US FAERS
486Tongue eruptionFAERS: 1US FAERS
487Transcription medication errorFAERS: 1US FAERS
488Ultrasound Doppler abnormalFAERS: 1US FAERS
489Urge IncontinenceFAERS: 1US FAERS
490Vaginal cellulitisFAERS: 1US FAERS
491Vaginal mucosal blisteringFAERS: 1US FAERS
492VasculitisFAERS: 117052533CTD
US FAERS
493Venous ThrombosisFAERS: 1US FAERS
494Vitreous DetachmentFAERS: 1US FAERS
495Vitreous floatersFAERS: 1US FAERS
496VulvitisFAERS: 1OFFSIDES
SIDER
US FAERS
497Vulvovaginal discomfortFAERS: 1US FAERS
498Vulvovaginal pruritusFAERS: 1US FAERS
499Walking aid userFAERS: 1US FAERS
500WheezingFAERS: 1US FAERS
501Wound ComplicationFAERS: 1US FAERS
502Wrong product administeredFAERS: 1US FAERS
503keratoacanthomaFAERS: 1US FAERS
504prostatitisFAERS: 1US FAERS
505Absolute neutrophil count decreasedSIDER
506Acid refluxOFFSIDES
507Allergy aggravatedSIDER
508Allergy to animalOFFSIDES
509AnhidrosisOFFSIDES
510Animal biteOFFSIDES
511ApneaOFFSIDES
512Application site cellulitisSIDER
513Application site skin breakdownSIDER
514ArteriosclerosisOFFSIDES
515AtaxiaCanada Vigilance: 1Canada Vigilance
516Atrophic vulvovaginitisSIDER
517Bacterial sepsisOFFSIDES
518Biopsy site unspecified abnormalOFFSIDES
519BiopsyOFFSIDES
520Bipolar DisorderOFFSIDES
521Blood and lymphatic system disordersSIDER
522Blood glucose decreasedOFFSIDES
523Blood immunoglobulin MOFFSIDES
524Bone density decreasedOFFSIDES
525Bone lesionOFFSIDES
526BronchomalaciaOFFSIDES
527BruxismOFFSIDES
528Carcinoma, Basal Cell16302556
17052533
31111189
CTD
529Cardiac HypertrophyOFFSIDES
530Cardioactive drug levelOFFSIDES
531Central venous catheter removalOFFSIDES
532Chemotherapeutic drug level increasedOFFSIDES
533Chronic sinusitisOFFSIDES
534Circumstance or information capable of leading to medication errorOFFSIDES
535Common wartSIDER
536Condylomata Acuminata11362904
16302556
CTD
537Congenital heart diseaseOFFSIDES
538Congenital pyelocaliectasisOFFSIDES
539Congenital tracheomalaciaOFFSIDES
540Conjunctival depositOFFSIDES
541Conjunctival irritationSIDER
542Creatinine renal clearance decreasedOFFSIDES
543CystCanada Vigilance: 1Canada Vigilance
OFFSIDES
SIDER
544Cytokine abnormalCanada Vigilance: 1Canada Vigilance
545DebridementOFFSIDES
546Depressive disorder31111189CTD
547Diabetic NephropathyOFFSIDES
548Drug abuserOFFSIDES
549Drug addictOFFSIDES
550Drug withdrawal headacheOFFSIDES
551Dry gangreneOFFSIDES
552Dupuytren Contracture16368197CTD
553DysarthriaCanada Vigilance: 1Canada Vigilance
554DyspareuniaOFFSIDES
SIDER
555Dysthymic DisorderOFFSIDES
556Ear and labyrinth disordersSIDER
557Ear discomfortCanada Vigilance: 1Canada Vigilance
558Edema31111189CTD
559Emotional distressCanada Vigilance: 1Canada Vigilance
560Erectile dysfunctionSIDER
561ExcoriationOFFSIDES
SIDER
562ExencephalySIDER
563Fatty LiverOFFSIDES
564Fever31111189CTD
565FolliculitisSIDER
566Free prostate-specific antigen increasedOFFSIDES
567GoutSIDER
568Hemangioendothelioma14708627CTD
569Hemangioma16302556CTD
570Hepatic lymphomaSIDER
571HerniaSIDER
572Hilar lymphadenopathyOFFSIDES
573Hutchinson's Melanotic Freckle16302556CTD
574HypokinesiaCanada Vigilance: 1Canada Vigilance
575HypomaniaOFFSIDES
576ImmobileSIDER
577IncoherentCanada Vigilance: 1Canada Vigilance
OFFSIDES
578InfestationSIDER
579Inflicted injurySIDER
580Influenza-like symptomsSIDER
581Instillation site painSIDER
582Intervertebral disc disorderOFFSIDES
583Keratosis16302556CTD
584LaryngoceleOFFSIDES
585LaryngomalaciaOFFSIDES
586LeukodermaSIDER
587Loose toothOFFSIDES
588Loss of personal independence in daily activitiesCanada Vigilance: 3Canada Vigilance
589Low set earsSIDER
590MalnutritionSIDER
591Mass excisionOFFSIDES
592Mechanical ventilationOFFSIDES
593Metastatic painOFFSIDES
594Multiple MyelomaOFFSIDES
595Muscle WeaknessOFFSIDES
596Muscle necrosisOFFSIDES
597Muscle strainOFFSIDES
598Muscle tightnessOFFSIDES
599Musculoskeletal discomfortSIDER
600Neutrophil count decreasedSIDER
601NoduleCanada Vigilance: 1Canada Vigilance
602OnychalgiaOFFSIDES
603Otitis MediaSIDER
604Perirectal abscessOFFSIDES
605PharyngitisSIDER
606PhototoxicitySIDER
607Physical disabilityCanada Vigilance: 1Canada Vigilance
608PlasmacytomaOFFSIDES
609Portal HypertensionOFFSIDES
610Procedural site reactionSIDER
611Protein urine presentSIDER
612ProteinuriaSIDER
613Pseudomonal sepsisOFFSIDES
614Psoriasis flare-upSIDER
615Pulmonary InfarctionOFFSIDES
616Pyoderma GangrenosumOFFSIDES
617Rectal tenesmusSIDER
618Reflux laryngitisOFFSIDES
619Respiratory tract congestionOFFSIDES
SIDER
620RhinitisSIDER
621Right Ventricular HypertrophyOFFSIDES
622ShockSIDER
623Sjogren's SyndromeCanada Vigilance: 1Canada Vigilance
624Skin lacerationOFFSIDES
625SuicideSIDER
626Tinea crurisSIDER
627Tooth ExtractionOFFSIDES
628Trichostasis spinulosaOFFSIDES
629Tryptase increasedOFFSIDES
630Unexpected therapeutic drug effectOFFSIDES
631Urinary tract infectionSIDER
632Uterovaginal prolapseSIDER
633Vaginal painSIDER
634Viral pharyngitisOFFSIDES
635Vulvovaginal painSIDER
636Warts12852385
16368197
31111189
CTD
SIDER
637effusionOFFSIDES
638pustuleSIDER
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