MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sacroiliitis

(UMLS:C0574960)

Definition:: Inflammation of the SACROILIAC JOINT. It is characterized by lower back pain, especially upon walking, fever, UVEITIS; PSORIASIS; and decreased range of motion. Many factors are associated with and cause sacroiliitis including infection; injury to spine, lower back, and pelvis; DEGENERATIVE ARTHRITIS; and pregnancy.
UMLS ID:: C0574960
MeSH ID:: D058566

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.114.854

Synonym(s)

Sacroiliitis

Inflammation of sacroiliac joint

Inflammation of sacroiliac joint, NOS

SACROILEITIS

SACROILIITIS

Sacroiliac joint active

Sacroiliac joint arthritis

Sacroiliac joint inflamed

Sacroiliitis, NOS

10.

inflammation joint sacroiliac

11.

inflammation of sacroiliac joint

12.

inflammation sacroiliac

13.

inflammation; joint, sacroiliac

14.

joint; inflammation, sacroiliac

15.

sacroileitis

16.

sacroiliac inflammation

17.

sacroiliac joint inflammation

18.

sacroiliitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Isotretinoin	FAERS: 152	17725657 19533139	CTD US FAERS
2	Alendronate	FAERS: 8		OFFSIDES US FAERS
3	rofecoxib	FAERS: 7		OFFSIDES US FAERS
4	Buprenorphine	FAERS: 4		OFFSIDES US FAERS
5	Pregabalin	FAERS: 4		US FAERS
6	Finasteride	FAERS: 3		US FAERS
7	paricalcitol	FAERS: 3		US FAERS
8	Buprenorphine	FAERS: 2		US FAERS
9	Fingolimod Hydrochloride	FAERS: 2		US FAERS
10	NuvaRing	FAERS: 2		US FAERS
11	Zoledronic Acid	FAERS: 2		OFFSIDES US FAERS
12	haloperidol decanoate	FAERS: 2		OFFSIDES US FAERS
13	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
14	AN2728	FAERS: 1		US FAERS
15	Albuterol	FAERS: 1		US FAERS
16	Atorvastatin	FAERS: 1		US FAERS
17	Dasatinib	FAERS: 1		US FAERS
18	Dimethyl Fumarate	FAERS: 1		US FAERS
19	Emtricitabine, Rilpivirine, Tenofovir Drug Combination	FAERS: 1		US FAERS
20	Ibandronic Acid	FAERS: 1		US FAERS
21	Levofloxacin	FAERS: 1		US FAERS
22	Metoprolol	FAERS: 1		US FAERS
23	Norgestrel	FAERS: 1		US FAERS
24	Oseltamivir	FAERS: 1		US FAERS
25	Simvastatin	FAERS: 1		US FAERS
26	Thyroxine	FAERS: 1		US FAERS
27	adefovir dipivoxil	FAERS: 1		US FAERS
28	teriflunomide	FAERS: 1		US FAERS
29	Adapalene			OFFSIDES
30	Allopurinol			OFFSIDES
31	Amantadine			OFFSIDES
32	Atovaquone			OFFSIDES
33	Azathioprine			OFFSIDES
34	Beclomethasone			OFFSIDES
35	Beclomethasone			OFFSIDES
36	Benzoyl Peroxide			OFFSIDES
37	Bupropion			OFFSIDES
38	Calcium Carbonate			OFFSIDES
39	Cefoxitin			OFFSIDES
40	Ciprofloxacin			OFFSIDES
41	Citalopram			SIDER
42	Clindamycin			OFFSIDES
43	Cortisone			OFFSIDES
44	D-Galactosamine			OFFSIDES
45	Dapsone			OFFSIDES
46	Dexamethasone			OFFSIDES
47	Diazepam			OFFSIDES
48	Diclofenac			OFFSIDES
49	Diphenoxylate			OFFSIDES
50	Econazole			OFFSIDES
51	Ephedrine			OFFSIDES
52	Ertapenem			OFFSIDES
53	Erythromycin			OFFSIDES
54	Estrogens, Conjugated (USP)			OFFSIDES
55	Etodolac		19533139	CTD
56	Fosinopril			OFFSIDES
57	Hydralazine			OFFSIDES
58	Ibandronic Acid			OFFSIDES
59	Ibuprofen			OFFSIDES
60	Ketoprofen			OFFSIDES
61	Lenalidomide			OFFSIDES
62	Letrozole			OFFSIDES
63	Linezolid			OFFSIDES
64	Lisinopril			OFFSIDES
65	Loratadine			OFFSIDES
66	Memantine			OFFSIDES
67	Meperidine			OFFSIDES
68	Mesalamine			OFFSIDES
69	Methocarbamol			OFFSIDES
70	Methyltestosterone			OFFSIDES
71	Minocycline			OFFSIDES
72	Moxifloxacin			OFFSIDES
73	Naltrexone			OFFSIDES
74	Nitrous Oxide			OFFSIDES
75	Oxaprozin			OFFSIDES
76	Pamidronate			OFFSIDES
77	Paroxetine			OFFSIDES
78	Penicillin V			OFFSIDES
79	Pentoxifylline			OFFSIDES
80	Piroxicam			OFFSIDES
81	Raloxifene Hydrochloride			OFFSIDES
82	Scopolamine			OFFSIDES
83	Sumatriptan			OFFSIDES
84	Tetracycline			OFFSIDES
85	Tiagabine			OFFSIDES
86	Toremifene			OFFSIDES
87	Tretinoin			OFFSIDES
88	Trimethoprim, Sulfamethoxazole Drug Combination			OFFSIDES
89	Valacyclovir			OFFSIDES
90	anagrelide			OFFSIDES
91	cefuroxime axetil			OFFSIDES
92	magnesium citrate			OFFSIDES
93	olsalazine			OFFSIDES
94	ropinirole			SIDER
95	tegaserod			OFFSIDES
96	tegaserod			OFFSIDES
97	tizanidine			OFFSIDES
98	trimethobenzamide			OFFSIDES
99	trospium chloride			OFFSIDES
100	zaleplon			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Periarthritis	44.4%
2	Arthritis, Infectious	31.8%
3	Osteoarthritis, Spine	31.6%
4	Arthritis, Experimental	31.1%
5	Bursitis	31%
6	Joint Instability	31%
7	Synovitis	31%
8	Joint laxity	31%
9	Frozen shoulder	31%
10	Patellofemoral Pain Syndrome	31%
11	Arthritis, Psoriatic	31%
12	Rheumatic Fever	28.6%
13	Contracture	27.9%
14	Osteoarthropathy, Secondary Hypertrophic	27.9%
15	Osteoarthritis, Knee	27.5%
16	Arthritis, Reactive	26.4%
17	Ankylosing spondylitis	25.8%
18	Gout	25.6%
19	Spondylarthropathies	25.4%
20	Rheumatoid Arthritis	23.3%
21	Juvenile arthritis	23.3%
22	Arthrogryposis	20.8%
23	Metatarsalgia	20.5%
24	Rheumatoid Nodule	20.5%
25	Hemarthrosis	20.5%
26	Bone Diseases	18.5%
27	Fasciitis	18.5%
28	Foot Deformities	18.5%
29	Arthritis, Gouty	18.4%
30	Hip Contracture	17.8%
31	Felty Syndrome	16.4%
32	Temporomandibular Joint Disorders	14.4%
33	Fasciitis, Plantar	14%
34	Rheumatoid Vasculitis	13.7%
35	Ischemic contracture	13.3%
36	Jaw Diseases	12.8%
37	Nail-Patella Syndrome	12.3%
38	Cartilage Diseases	12.2%
39	Foot Diseases	12.2%
40	Myopathy	12.2%
41	Rheumatism	12.2%
42	Chondromalacia	12.2%
43	Arthralgia	11.9%
44	Polyarthralgia	11.9%
45	Sicca Syndrome	11.7%
46	Sjogren's Syndrome	11.7%
47	Bone Diseases, Developmental	10.3%
48	Fibromyalgia	10.3%
49	Hip Dislocation	10.3%
50	Hyperostosis	10.3%
51	Myofascial Pain Syndromes	10.3%
52	Osteitis	10.3%
53	Osteitis Deformans	10.3%
54	Osteochondritis	10.3%
55	Osteochondrosis	10.3%
56	Polymyalgia Rheumatica	10.3%
57	Rhabdomyolysis	10.3%
58	Shoulder Dislocation	10.3%
59	Spinal Diseases	10.3%
60	Hip Dysplasia	10.3%
61	Temporomandibular Joint Dysfunction Syndrome	10.1%
62	Pectus carinatum	9.1%
63	Pectus excavatum	8.5%
64	Platybasia	7.9%
65	Shoulder Pain	7.8%
66	Klippel-Feil Syndrome	7.6%
67	Synostosis	7.6%
68	Bone Diseases, Endocrine	7.3%
69	Bone Diseases, Infectious	7%
70	Bone neoplasms	7%
71	Compartment syndromes	7%
72	Maxillary Diseases	7%
73	Osteopenia	7%
74	Tendinitis	7%
75	Tendinopathy	7%
76	Talipes	6.9%
77	Bone Resorption	6.8%
78	Myositis	6.8%
79	Tietze's Syndrome	6.8%
80	Limb Deformities, Congenital	6.8%
81	Isaacs syndrome	6.8%
82	Craniofacial Abnormalities	6.8%
83	Aseptic Necrosis of Bone	6.8%
84	Myotonic Disorders	6.8%
85	Ainhum	6.7%
86	Bunion	6.7%
87	Dysostoses	6.7%
88	Fibrodysplasia Ossificans Progressiva	6.7%
89	Gigantism	6.7%
90	Myoglobinuria	6.7%
91	Myositis Ossificans	6.7%
92	Spinal Neoplasms	6.7%
93	Spinal Stenosis	6.7%
94	Spondylitis	6.7%
95	Spondylosis	6.7%
96	Tenosynovitis	6.7%
97	Intervertebral Disc Degeneration	6.7%
98	Craniofacial Dysostosis	5.7%
99	Craniosynostosis	5.7%
100	Syndactyly	5.7%
101	Brachycephaly	5.7%
102	Congenital clubfoot	5.3%
103	Vertical Talus	5.3%
104	Medial Tibial Stress Syndrome	5.2%
105	Mitochondrial Myopathies	5.1%
106	Muscle Cramp	5%
107	Eosinophilia-Myalgia Syndrome	5%
108	Gastroschisis	5%
109	Muscle Rigidity	5%
110	Muscle Spasticity	5%
111	Cogwheel Rigidity	5%
112	Nuchal Rigidity	5%
113	Chondrodysplasia Punctata	4.9%
114	Enchondromatosis	4.9%
115	Lordosis	4.9%
116	Osteosclerosis	4.9%
117	Spondylolysis	4.9%
118	kyphosis	4.9%
119	Kashin-Beck Disease	4.9%
120	Discitis	4.9%
121	Acrocephalosyndactylia	4.8%
122	Multiple Epiphyseal Dysplasia	4.5%
123	Osteochondrodysplasias	4.5%
124	Anterior Compartment Syndrome	4.4%
125	Osteomyelitis	4.4%
126	Osteoporosis	4.4%
127	Periostitis	4.4%
128	Enthesopathy	4.4%
129	Bone Demineralization, Pathologic	4.4%
130	Post-Traumatic Osteoporosis	4.4%
131	Abdominal Compartment Syndrome	4.4%
132	Poland Syndrome	4.4%
133	Alveolar Bone Loss	4.4%
134	Amelia	4.4%
135	Arachnodactyly	4.4%
136	Ectromelia	4.4%
137	Femur Head Necrosis	4.4%
138	Hemimelia	4.4%
139	Phocomelia	4.4%
140	Sirenomelia	4.4%
141	Polymyositis	4.4%
142	Polydactyly	4.4%
143	Brachydactyly	4.4%
144	Plagiocephaly	4.4%
145	Lower Extremity Deformities, Congenital	4.4%
146	Upper Extremity Deformities, Congenital	4.4%
147	Osteolysis	4.4%
148	Jaw Abnormalities	4.3%
149	Chronic Fatigue Syndrome	4.3%
150	Giant Cell Epulis	4.1%
151	Muscle Weakness	4.1%
152	Melorheostosis	4.1%
153	Osteopetrosis	4.1%
154	Spondylolisthesis	4.1%
155	Musculoskeletal Pain	4%
156	Familial Periodic Paralysis	4%
157	Congenital Hypothyroidism	3.9%
158	Tuberculosis, Spinal	3.9%
159	Prognathism	3.8%
160	Goldenhar Syndrome	3.8%
161	Dwarfism	3.6%
162	Mandibulofacial Dysostosis	3.6%
163	Antley-Bixler Syndrome Phenotype	3.5%
164	Laryngomalacia	3.4%
165	Muscular Dystrophy	3.4%
166	Orbital Myositis	3.4%
167	Dupuytren Contracture	3.3%
168	Eosinophilic Granuloma	3.3%
169	Myalgia	3.3%
170	Pyomyositis	3.3%
171	Acromegaly	3.3%
172	Joint Tuberculosis	3.3%
173	Tuberculosis, Osteoarticular	3.3%
174	Bone Tuberculosis	3.3%
175	Osteoporosis, Postmenopausal	3.3%
176	Palatal Neoplasms	3%
177	Micrognathism	3%
178	Pierre Robin Syndrome	3%
179	Rubinstein-Taybi Syndrome	2.9%
180	Myotonic Dystrophy	2.9%
181	Maxillofacial Abnormalities	2.7%
182	Myotonia Congenita	2.6%
183	Retrognathia	2.6%
184	Rickets	2.6%
185	Bronchomalacia	2.6%
186	Tracheomalacia	2.6%
187	Microcephaly	2.6%
188	Macrocephaly	2.6%
189	Hypokalemic periodic paralysis	2.6%
190	Osteogenesis Imperfecta	2.5%
191	Welander Distal Myopathy	2.4%
192	Mastoiditis	2.4%
193	Petrositis	2.4%
194	Basal Cell Nevus Syndrome	2.3%
195	Pseudohypoparathyroidism	2.2%
196	Mitochondrial Encephalomyopathies	2.2%
197	Cleft Palate	2.1%
198	Dermatomyositis	2%
199	Muscular Dystrophy, Duchenne	2%
200	Osteomalacia	1.9%
201	Porencephaly	1.9%
202	Noonan Syndrome	1.9%
203	Marfan Syndrome	1.7%
204	Holoprosencephaly	1.7%
205	Cockayne Syndrome	1.4%
206	Radicular Cyst	1.3%
207	Nose Neoplasms	1.3%
208	Renal Osteodystrophy	1.2%
209	Renal rickets	1.2%
210	MELAS Syndrome	1%
211	Kearns-Sayre syndrome	0.9%
212	Familial Hypophosphatemic Rickets	0.6%

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