MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hyperostosis

(UMLS:C0020492)

Definition:: Increase in the mass of bone per unit volume.
UMLS ID:: C0020492
MeSH ID:: D015576

Classification:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.540

Synonym(s)

Hyperostosis

Bone Hypertrophy

Bone hypertrophy

Bone overgrowth

Bony overgrowth

HYPEROSTOSIS

Hyperostosis, NOS

Hypertrophy of bone

Hypertrophy of bone, NOS

10.

Hypertrophy of bone, site unspecified

11.

Hypertrophy of bone, unspecified site

12.

bone hypertrophy

13.

bone; hypertrophy

14.

bony overgrowth

15.

hyperostosis

16.

hypertrophy of bone

17.

hypertrophy; bone

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acitretin		SIDER
2	Canagliflozin	25289773 28916336	CTD
3	Glucose	28916336	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Bone Diseases, Developmental	42.9%
2	Osteitis	42.9%
3	Osteitis Deformans	42.9%
4	Osteochondrosis	42.9%
5	Spinal Diseases	42.9%
6	Osteoarthropathy, Secondary Hypertrophic	38.1%
7	Ainhum	31%
8	Dysostoses	31%
9	Spinal Stenosis	31%
10	Spondylosis	31%
11	Intervertebral Disc Degeneration	31%
12	Gigantism	30.5%
13	Spinal Neoplasms	30.5%
14	Spondylitis	30.5%
15	Bone Diseases, Endocrine	30%
16	Bone Diseases, Infectious	28.6%
17	Bone neoplasms	28.6%
18	Osteopenia	28.6%
19	Platybasia	28.2%
20	Osteochondritis	28.1%
21	Bone Resorption	27.9%
22	Aseptic Necrosis of Bone	27.9%
23	Chondrodysplasia Punctata	25.4%
24	Enchondromatosis	25.4%
25	Lordosis	25.4%
26	Osteosclerosis	25.4%
27	Spondylolysis	25.4%
28	kyphosis	25.4%
29	Kashin-Beck Disease	25.4%
30	Discitis	24.8%
31	Fasciitis	23.1%
32	Foot Deformities	23.1%
33	Arthropathy	23.1%
34	Melorheostosis	22.7%
35	Osteopetrosis	22.7%
36	Spondylolisthesis	22.7%
37	Pectus excavatum	22.4%
38	Multiple Epiphyseal Dysplasia	20.9%
39	Osteochondrodysplasias	20.9%
40	Osteomyelitis	20.5%
41	Osteoporosis	20.5%
42	Periostitis	20.5%
43	Bone Demineralization, Pathologic	20.5%
44	Post-Traumatic Osteoporosis	20.5%
45	Spondylarthropathies	20.4%
46	Alveolar Bone Loss	20.2%
47	Femur Head Necrosis	20.2%
48	Osteolysis	20.2%
49	Klippel-Feil Syndrome	19.7%
50	Synostosis	19.7%
51	Tuberculosis, Spinal	19.6%
52	Pectus carinatum	19.5%
53	Osteoarthritis, Spine	19.5%
54	Ankylosing spondylitis	19.2%
55	Contracture	19%
56	Fasciitis, Plantar	19%
57	Congenital Hypothyroidism	18.6%
58	Craniofacial Dysostosis	17.5%
59	Arthrogryposis	16.9%
60	Osteoporosis, Postmenopausal	16.7%
61	Dwarfism	16.4%
62	Jaw Diseases	15.8%
63	Arthritis, Psoriatic	15.3%
64	Acromegaly	15%
65	Joint Tuberculosis	15%
66	Tuberculosis, Osteoarticular	15%
67	Bone Tuberculosis	15%
68	Cartilage Diseases	15%
69	Foot Diseases	15%
70	Myopathy	15%
71	Rheumatism	15%
72	Chondromalacia	15%
73	Arthritis, Reactive	14.6%
74	Arthritis	14.3%
75	Bursitis	14.3%
76	Joint Instability	14.3%
77	Myofascial Pain Syndromes	14.3%
78	Rhabdomyolysis	14.3%
79	Synovitis	14.3%
80	Joint laxity	14.3%
81	Polyarthritis	14.3%
82	Frozen shoulder	14.3%
83	Patellofemoral Pain Syndrome	14.3%
84	Craniosynostosis	14%
85	Syndactyly	14%
86	Brachycephaly	14%
87	Fibromyalgia	14%
88	Polymyalgia Rheumatica	14%
89	Goldenhar Syndrome	14%
90	Metatarsalgia	13.9%
91	Hip Contracture	13.6%
92	Periarthritis	13.6%
93	Eosinophilic Granuloma	13.4%
94	Acrocephalosyndactylia	13.3%
95	Osteogenesis Imperfecta	12.8%
96	Mastoiditis	12.4%
97	Petrositis	12.4%
98	Osteoarthritis, Knee	12.4%
99	Poland Syndrome	12.3%
100	Mandibulofacial Dysostosis	12.2%
101	Ischemic contracture	12.2%
102	Rickets	12%
103	Rheumatic Fever	12%
104	Gout	11.2%
105	Temporomandibular Joint Disorders	11%
106	Talipes	10.9%
107	Antley-Bixler Syndrome Phenotype	10.7%
108	Bunion	10.3%
109	Fibrodysplasia Ossificans Progressiva	10.3%
110	Myoglobinuria	10.3%
111	Myositis Ossificans	10.3%
112	Tenosynovitis	10.3%
113	Sacroiliitis	10.3%
114	Temporomandibular Joint Dysfunction Syndrome	10.2%
115	Pseudohypoparathyroidism	10%
116	Osteomalacia	9.8%
117	Rheumatoid Arthritis	9.7%
118	Juvenile arthritis	9.7%
119	Compartment syndromes	9.5%
120	Maxillary Diseases	9.5%
121	Tendinitis	9.5%
122	Tendinopathy	9.5%
123	Hemarthrosis	9.3%
124	Myositis	9.3%
125	Tietze's Syndrome	9.3%
126	Limb Deformities, Congenital	9.3%
127	Isaacs syndrome	9.3%
128	Craniofacial Abnormalities	9.3%
129	Myotonic Disorders	9.3%
130	Congenital clubfoot	9.3%
131	Vertical Talus	9.3%
132	Palatal Neoplasms	9.2%
133	Rheumatoid Nodule	9.2%
134	Arthritis, Gouty	8.7%
135	Rubinstein-Taybi Syndrome	8.7%
136	Marfan Syndrome	7.7%
137	Basal Cell Nevus Syndrome	7.6%
138	Felty Syndrome	7.3%
139	Cockayne Syndrome	7.2%
140	Medial Tibial Stress Syndrome	7%
141	Arthritis, Infectious	7%
142	Mitochondrial Myopathies	6.9%
143	Muscle Cramp	6.8%
144	Eosinophilia-Myalgia Syndrome	6.8%
145	Gastroschisis	6.8%
146	Anterior Compartment Syndrome	6.8%
147	Enthesopathy	6.8%
148	Arthritis, Experimental	6.8%
149	Abdominal Compartment Syndrome	6.8%
150	Muscle Rigidity	6.8%
151	Muscle Spasticity	6.8%
152	Cogwheel Rigidity	6.8%
153	Nuchal Rigidity	6.8%
154	Amelia	6.7%
155	Arachnodactyly	6.7%
156	Ectromelia	6.7%
157	Hemimelia	6.7%
158	Phocomelia	6.7%
159	Sirenomelia	6.7%
160	Polymyositis	6.7%
161	Polydactyly	6.7%
162	Brachydactyly	6.7%
163	Plagiocephaly	6.7%
164	Lower Extremity Deformities, Congenital	6.7%
165	Upper Extremity Deformities, Congenital	6.7%
166	Nose Neoplasms	6.4%
167	Jaw Abnormalities	6.3%
168	Renal Osteodystrophy	6.1%
169	Renal rickets	6.1%
170	Rheumatoid Vasculitis	6.1%
171	Prognathism	6%
172	Chronic Fatigue Syndrome	5.8%
173	Nail-Patella Syndrome	5.6%
174	Giant Cell Epulis	5.5%
175	Muscle Weakness	5.5%
176	Musculoskeletal Pain	5.4%
177	Familial Periodic Paralysis	5.4%
178	Arthralgia	5.4%
179	Polyarthralgia	5.4%
180	Hip Dislocation	5.3%
181	Shoulder Dislocation	5.3%
182	Hip Dysplasia	5.3%
183	Sicca Syndrome	5.2%
184	Sjogren's Syndrome	5.2%
185	Muscular Dystrophy	5.1%
186	Orbital Myositis	5.1%
187	Dupuytren Contracture	5.1%
188	Pyomyositis	5%
189	Micrognathism	4.9%
190	Pierre Robin Syndrome	4.9%
191	Laryngomalacia	4.7%
192	Myotonic Dystrophy	4.6%
193	Myalgia	4.5%
194	Retrognathia	4.3%
195	Welander Distal Myopathy	4.1%
196	Maxillofacial Abnormalities	4.1%
197	Myotonia Congenita	4%
198	Bronchomalacia	4%
199	Tracheomalacia	4%
200	Microcephaly	4%
201	Macrocephaly	4%
202	Hypokalemic periodic paralysis	3.9%
203	Shoulder Pain	3.9%
204	Cleft Palate	3.4%
205	Dermatomyositis	3.4%
206	Muscular Dystrophy, Duchenne	3.3%
207	Familial Hypophosphatemic Rickets	3.3%
208	Mitochondrial Encephalomyopathies	3.3%
209	Porencephaly	3.3%
210	Noonan Syndrome	2.9%
211	Holoprosencephaly	2.5%
212	Radicular Cyst	2.4%
213	MELAS Syndrome	1.6%
214	Kearns-Sayre syndrome	1.5%

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