MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Bone Resorption

(UMLS:C0005974)

Definition:: Bone loss due to osteoclastic activity.
UMLS ID:: C0005974
MeSH ID:: D001862

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.264

Classification 2:

Name:

Musculoskeletal and Neural Physiological Phenomena
MeSH Tree Number(s):: G11.427.213.150

Synonym(s)

Bone Resorption

Bone resorption

Bone resorption, NOS

Bone resorption, function

bone resorption

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3-(4-methoxy)phenyl-4-((4-(2-(1-piperidinyl)ethoxy)phenyl)methyl)-2H-1-benzopyran-7-ol	16294271	CTD
2	Alcohols	24872432	CTD
3	Alendronate	View details 9556058 11961144 19405951 29649498	CTD
4	Aluminum Chloride	30292833	CTD
5	Beclomethasone	2028429	CTD
6	Berberine	9881647	CTD
7	Cadmium Compounds	23954550	CTD
8	Clodronic Acid	8913344 11961144 19405951	CTD
9	Cocaine	16160570	CTD
10	Copper Sulfate	16847394	CTD
11	Hesperidin	21820093	CTD
12	Histamine	14751566	CTD
13	Leflunomide	26221077	CTD
14	Meprednisone	26851681	CTD
15	Modafinil	29649498	CTD
16	Niclosamide	26792726	CTD
17	Nicotinamide Mononucleotide	30292833	CTD
18	Pamidronate	8053405 8913344 15845617	CTD
19	Puromycin Aminonucleoside	9154658	CTD
20	Resveratrol	21715682	CTD
21	Rotenone	19900598	CTD
22	Sirolimus	26369790	CTD
23	Theophylline	26851681	CTD
24	Thymol	30048646	CTD
25	Trinitrobenzenesulfonic Acid	23747339	CTD
26	Uranium	29477364	CTD
27	Yohimbine	27028940	CTD
28	Zoledronic Acid	View details 8053405 11869084 15845617 16769263 18404659 18496637	CTD
29	betulinic acid	24463094	CTD
30	bisphenol A	11985600	CTD
31	fatostatin	26319416	CTD
32	limonin	9881647	CTD
33	mangiferin	9881647	CTD
34	mevastatin	9556058	CTD
35	naringin	21820093 21835177	CTD
36	norisoboldine	26221077	CTD
37	rhodioloside	24055767	CTD
38	syringin	9881647	CTD
39	tofacitinib	22899318	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Osteoarthropathy, Secondary Hypertrophic	28.1%
2	Bone Diseases, Developmental	27.9%
3	Hyperostosis	27.9%
4	Osteitis	27.9%
5	Osteitis Deformans	27.9%
6	Osteochondrosis	27.9%
7	Spinal Diseases	27.9%
8	Gigantism	24.3%
9	Spinal Neoplasms	24.3%
10	Spondylitis	24.3%
11	Platybasia	23.5%
12	Osteochondritis	22.2%
13	Bone Diseases, Endocrine	21.8%
14	Bone Diseases, Infectious	21.1%
15	Bone neoplasms	21.1%
16	Osteopenia	21.1%
17	Muscle Fatigue	20.9%
18	Muscle tightness	20.9%
19	Aseptic Necrosis of Bone	20.7%
20	Dysostoses	20.5%
21	Spinal Stenosis	20.5%
22	Spondylosis	20.5%
23	Intervertebral Disc Degeneration	20.5%
24	Discitis	19.9%
25	Pectus excavatum	17.8%
26	Chondrodysplasia Punctata	16.9%
27	Enchondromatosis	16.9%
28	Lordosis	16.9%
29	Osteosclerosis	16.9%
30	Spondylolysis	16.9%
31	kyphosis	16.9%
32	Kashin-Beck Disease	16.9%
33	Pectus carinatum	16.7%
34	Tuberculosis, Spinal	16.4%
35	Osteoarthritis, Spine	16.3%
36	Congenital Hypothyroidism	15.9%
37	Klippel-Feil Syndrome	15.6%
38	Synostosis	15.6%
39	Multiple Epiphyseal Dysplasia	15.5%
40	Osteochondrodysplasias	15.5%
41	Ankylosing spondylitis	15.4%
42	Spondylarthropathies	15.4%
43	Osteomyelitis	15.3%
44	Osteoporosis	15.3%
45	Periostitis	15.3%
46	Bone Demineralization, Pathologic	15.3%
47	Post-Traumatic Osteoporosis	15.3%
48	Femur Head Necrosis	15.1%
49	Melorheostosis	15.1%
50	Osteopetrosis	15.1%
51	Spondylolisthesis	15.1%
52	Fasciitis	14.6%
53	Foot Deformities	14.6%
54	Arthropathy	14.6%
55	Contracture	14%
56	Fasciitis, Plantar	14%
57	Craniofacial Dysostosis	14%
58	Arthrogryposis	14%
59	Prone Position	13.6%
60	Dwarfism	12.9%
61	Arthritis, Psoriatic	12.8%
62	Osteoporosis, Postmenopausal	12.5%
63	Acrocephalosyndactylia	12.2%
64	Arthritis, Reactive	12.2%
65	Craniosynostosis	12.1%
66	Syndactyly	12.1%
67	Brachycephaly	12.1%
68	Acromegaly	12%
69	Joint Tuberculosis	12%
70	Tuberculosis, Osteoarticular	12%
71	Bone Tuberculosis	12%
72	Eosinophilic Granuloma	11.5%
73	Jaw Diseases	11.3%
74	Goldenhar Syndrome	11.3%
75	Fibromyalgia	11.1%
76	Polymyalgia Rheumatica	11.1%
77	Metatarsalgia	11%
78	Cartilage Diseases	10.9%
79	Foot Diseases	10.9%
80	Myopathy	10.9%
81	Rheumatism	10.9%
82	Chondromalacia	10.9%
83	Poland Syndrome	10.6%
84	Osteogenesis Imperfecta	10.2%
85	Hip Contracture	10.2%
86	Periarthritis	10.2%
87	Mandibulofacial Dysostosis	10.2%
88	Ischemic contracture	10.1%
89	Rickets	10%
90	Mastoiditis	9.9%
91	Petrositis	9.9%
92	Gout	9.6%
93	Rheumatic Fever	9.5%
94	Temporomandibular Joint Disorders	9.4%
95	Arthritis	9.3%
96	Bursitis	9.3%
97	Joint Instability	9.3%
98	Myofascial Pain Syndromes	9.3%
99	Rhabdomyolysis	9.3%
100	Synovitis	9.3%
101	Joint laxity	9.3%
102	Polyarthritis	9.3%
103	Frozen shoulder	9.3%
104	Patellofemoral Pain Syndrome	9.3%
105	Osteoarthritis, Knee	9.2%
106	Antley-Bixler Syndrome Phenotype	9.2%
107	Talipes	9.1%
108	Temporomandibular Joint Dysfunction Syndrome	9%
109	Pseudohypoparathyroidism	8.6%
110	Osteomalacia	8.2%
111	Palatal Neoplasms	8.1%
112	Rheumatoid Arthritis	8%
113	Juvenile arthritis	8%
114	Congenital clubfoot	7.8%
115	Vertical Talus	7.8%
116	Rubinstein-Taybi Syndrome	7.7%
117	Arthritis, Gouty	7.5%
118	Rheumatoid Nodule	7.3%
119	Compartment syndromes	7%
120	Maxillary Diseases	7%
121	Tendinitis	7%
122	Tendinopathy	7%
123	Basal Cell Nevus Syndrome	6.9%
124	Hemarthrosis	6.9%
125	Myositis	6.9%
126	Tietze's Syndrome	6.9%
127	Limb Deformities, Congenital	6.9%
128	Isaacs syndrome	6.9%
129	Craniofacial Abnormalities	6.9%
130	Myotonic Disorders	6.9%
131	Bunion	6.8%
132	Fibrodysplasia Ossificans Progressiva	6.8%
133	Myoglobinuria	6.8%
134	Myositis Ossificans	6.8%
135	Tenosynovitis	6.8%
136	Sacroiliitis	6.8%
137	Marfan Syndrome	6.8%
138	Musculoskeletal Pain	6.8%
139	Cockayne Syndrome	6.3%
140	Arthralgia	6.1%
141	Polyarthralgia	6.1%
142	Felty Syndrome	6.1%
143	Nose Neoplasms	5.7%
144	Medial Tibial Stress Syndrome	5.6%
145	Mitochondrial Myopathies	5.5%
146	Jaw Abnormalities	5.5%
147	Renal Osteodystrophy	5.5%
148	Renal rickets	5.5%
149	Muscle Cramp	5.4%
150	Eosinophilia-Myalgia Syndrome	5.4%
151	Gastroschisis	5.4%
152	Prognathism	5.4%
153	Muscle Rigidity	5.4%
154	Muscle Spasticity	5.4%
155	Cogwheel Rigidity	5.4%
156	Nuchal Rigidity	5.4%
157	Myalgia	5.3%
158	Rheumatoid Vasculitis	5.2%
159	Arthritis, Infectious	5.2%
160	Anterior Compartment Syndrome	5.1%
161	Enthesopathy	5.1%
162	Arthritis, Experimental	5.1%
163	Abdominal Compartment Syndrome	5.1%
164	Amelia	5%
165	Arachnodactyly	5%
166	Ectromelia	5%
167	Hemimelia	5%
168	Phocomelia	5%
169	Sirenomelia	5%
170	Polymyositis	5%
171	Polydactyly	5%
172	Brachydactyly	5%
173	Plagiocephaly	5%
174	Lower Extremity Deformities, Congenital	5%
175	Upper Extremity Deformities, Congenital	5%
176	Chronic Fatigue Syndrome	4.8%
177	Shoulder Pain	4.7%
178	Nail-Patella Syndrome	4.6%
179	Giant Cell Epulis	4.6%
180	Muscle Weakness	4.6%
181	Sicca Syndrome	4.6%
182	Sjogren's Syndrome	4.6%
183	Familial Periodic Paralysis	4.5%
184	Micrognathism	4.3%
185	Pierre Robin Syndrome	4.3%
186	Hip Dislocation	4.2%
187	Shoulder Dislocation	4.2%
188	Hip Dysplasia	4.2%
189	Muscular Dystrophy	4.1%
190	Orbital Myositis	4.1%
191	Dupuytren Contracture	4.1%
192	Myotonic Dystrophy	4.1%
193	Pyomyositis	4%
194	Laryngomalacia	4%
195	Retrognathia	3.8%
196	Wakefulness	3.4%
197	Maxillofacial Abnormalities	3.4%
198	Myotonia Congenita	3.4%
199	Bronchomalacia	3.3%
200	Tracheomalacia	3.3%
201	Welander Distal Myopathy	3.3%
202	Microcephaly	3.3%
203	Macrocephaly	3.3%
204	Hypokalemic periodic paralysis	3.3%
205	Cleft Palate	3.1%
206	Familial Hypophosphatemic Rickets	3.1%
207	Mitochondrial Encephalomyopathies	2.8%
208	Dermatomyositis	2.8%
209	Muscular Dystrophy, Duchenne	2.8%
210	Piloerection	2.7%
211	Porencephaly	2.7%
212	Pain	2.7%
213	Ache	2.7%
214	Mastodynia	2.7%
215	Noonan Syndrome	2.5%
216	Somatosensory Evoked Potentials	2.5%
217	Gagging	2.3%
218	Holoprosencephaly	2.2%
219	Radicular Cyst	2.1%
220	Breakthrough Pain	2%
221	Reflex, Abnormal	1.9%
222	Hyporeflexia	1.9%
223	Hyperreflexia	1.9%
224	Renal Colic	1.7%
225	MELAS Syndrome	1.5%
226	Kearns-Sayre syndrome	1.4%

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