MetaADEDB 2.0 @ LMMD
Betamethasone
(UREBDLICKHMUKA-DVTGEIKXSA-N)
Structure
SMILES
OCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F
Type(s)
Approved; Vet_approved
ATC code(s)
A07EA04; C05AA05; D07AC01; D07BC01; D07CC01; D07XC01; H02AB01; R01AD06; R03BA04; S01BA06; S01BB04; S01CA05; S01CB04; S02BA07; S03BA03; S03CA06
Molecular Formula:
C22H29FO5
Molecular Weight:
392.461
Log P:
1.8957
Hydrogen Bond Acceptor:
5
Hydrogen Bond Donor:
3
TPSA:
94.83
CAS Number(s):
378-44-9
Synonym(s)
1.
Betamethasone
2.
Betadexamethasone
3.
Flubenisolone
4.
Celeston
5.
Celestona
6.
Celestone
7.
Cellestoderm
External Link(s)
MeSHD001623
PubChem Compound9782
BindingDB73823
ChEBI3077
CHEMBLCHEMBL632
DrugBankDB00443
DrugCentral348
IUPHAR/BPS Guide to PHARMACOLOGY7061
KEGGcpd:C06848
dr:D00244
Therapeutic Target DatabaseD0CW1P
D0Y4LP
D0J5MP
ZINC3876136
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Maternal exposure during pregnancyFAERS: 25
Canada Vigilance: 1		Canada Vigilance
US FAERS
2Low birth weight babyFAERS: 22US FAERS
3PainFAERS: 21
Canada Vigilance: 1		4407189
19863744		CTD
SIDER
Canada Vigilance
US FAERS
4Drug ineffectiveFAERS: 16
Canada Vigilance: 1		Canada Vigilance
US FAERS
5HeadacheFAERS: 16
Canada Vigilance: 1		Canada Vigilance
US FAERS
6ErythemaFAERS: 8
Canada Vigilance: 1		4241782CTD
SIDER
Canada Vigilance
US FAERS
7NauseaFAERS: 8US FAERS
8Neck PainFAERS: 7US FAERS
9AngioedemaFAERS: 6US FAERS
10AnxietyFAERS: 6US FAERS
11AstheniaFAERS: 6US FAERS
12HypersensitivityFAERS: 6SIDER
US FAERS
13Musculoskeletal PainFAERS: 6US FAERS
14AgitationFAERS: 5US FAERS
15DizzinessFAERS: 5US FAERS
16Drug exposure during pregnancyFAERS: 5US FAERS
17FatigueFAERS: 5US FAERS
18MalaiseFAERS: 5US FAERS
19Medication ErrorFAERS: 5US FAERS
20Optic AtrophyFAERS: 5US FAERS
21Pharmaceutical product complaintFAERS: 5US FAERS
22Sinusitis aspergillusFAERS: 5US FAERS
23VomitingFAERS: 5US FAERS
24AcneFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
25ArthralgiaFAERS: 4
Canada Vigilance: 1		Canada Vigilance
US FAERS
26CataractFAERS: 4US FAERS
27Dermatitis acneiformFAERS: 4SIDER
US FAERS
28Diabetes MellitusFAERS: 4US FAERS
29FlushingFAERS: 4US FAERS
30Incorrect dose administeredFAERS: 4US FAERS
31Incorrect route of drug administrationFAERS: 4US FAERS
32InfectionFAERS: 4SIDER
US FAERS
33Intentional product misuseFAERS: 4US FAERS
34Metabolic acidosisFAERS: 4US FAERS
35No adverse eventFAERS: 4US FAERS
36Product quality issueFAERS: 4US FAERS
37PruritusFAERS: 418058305CTD
SIDER
US FAERS
38UrticariaFAERS: 4SIDER
US FAERS
39Abdominal PainFAERS: 3US FAERS
40Adverse eventFAERS: 3US FAERS
41Back PainFAERS: 3US FAERS
42Blood glucose increasedFAERS: 3US FAERS
43CandidiasisFAERS: 3US FAERS
44CryingFAERS: 3US FAERS
45DeliriumFAERS: 3US FAERS
46Depressed Level of ConsciousnessFAERS: 3US FAERS
47HepatitisFAERS: 3US FAERS
48Hypertrophic CardiomyopathyFAERS: 3US FAERS
49Hypertrophic obstructive cardiomyopathyFAERS: 3US FAERS
50Hypothalamic pituitary adrenal axis suppressionFAERS: 3US FAERS
51Injection site necrosisFAERS: 3US FAERS
52Lipase increasedFAERS: 3US FAERS
53MyalgiaFAERS: 3US FAERS
54Nerve injuryFAERS: 3US FAERS
55PalpitationsFAERS: 3US FAERS
56Poor quality sleepFAERS: 3US FAERS
57Post procedural complicationFAERS: 3US FAERS
58Product use in unapproved indicationFAERS: 3US FAERS
59PurpuraFAERS: 3US FAERS
60Septic ShockFAERS: 3US FAERS
61Starvation ketoacidosisFAERS: 3US FAERS
62Vascular purpuraFAERS: 3US FAERS
63ArthritisFAERS: 2US FAERS
64AsthmaFAERS: 2US FAERS
65BlindnessFAERS: 25924702CTD
US FAERS
66Blood beta-D-glucan increasedFAERS: 2US FAERS
67Bone painFAERS: 2US FAERS
68Bullous lung diseaseFAERS: 2US FAERS
69Burning sensationFAERS: 2US FAERS
70Chest PainFAERS: 2US FAERS
71Chest discomfortFAERS: 2US FAERS
72Conversion disorderFAERS: 2US FAERS
73DisorientationFAERS: 2US FAERS
74Disseminated Intravascular CoagulationFAERS: 2US FAERS
75Drug DependenceFAERS: 2US FAERS
76DystoniaFAERS: 2US FAERS
77ExcitabilityFAERS: 2US FAERS
78Failure to ThriveFAERS: 2US FAERS
79Familial Mediterranean FeverFAERS: 2US FAERS
80General physical condition abnormalFAERS: 2US FAERS
81HemiplegiaFAERS: 2US FAERS
82HirsutismFAERS: 2US FAERS
83HypophagiaFAERS: 2US FAERS
84HypothyroidismFAERS: 2US FAERS
85Injection Site ReactionFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
86Injection site abscessFAERS: 2US FAERS
87Injection site painFAERS: 2US FAERS
88Joint Range of Motion DecreasedFAERS: 2US FAERS
89LymphopeniaFAERS: 2US FAERS
90MeningitisFAERS: 2US FAERS
91NasopharyngitisFAERS: 2US FAERS
92NeutropeniaFAERS: 2US FAERS
93OsteolysisFAERS: 2US FAERS
94OsteopeniaFAERS: 2US FAERS
95Pulmonary EmbolismFAERS: 27336895CTD
US FAERS
96Pulmonary HypertensionFAERS: 2US FAERS
97Respiratory distressFAERS: 2US FAERS
98RestlessnessFAERS: 2US FAERS
99SomnolenceFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
100StressFAERS: 2US FAERS
101SynovitisFAERS: 2US FAERS
102TorticollisFAERS: 2US FAERS
103nervous system disorderFAERS: 2US FAERS
104AbasiaFAERS: 1US FAERS
105Abdominal discomfortFAERS: 1US FAERS
106AbscessFAERS: 1US FAERS
107Accidental exposure to product by childFAERS: 1US FAERS
108Accidental overdoseFAERS: 1US FAERS
109Activities of daily living impairedFAERS: 1US FAERS
110Acute kidney injuryFAERS: 1US FAERS
111Allergic reaction to excipientFAERS: 1US FAERS
112Anaphylactic shockFAERS: 1US FAERS
113AnencephalyFAERS: 1US FAERS
114AnorexiaFAERS: 1US FAERS
115AnuriaFAERS: 1US FAERS
116ArachnoiditisFAERS: 1US FAERS
117ArthropathyFAERS: 1US FAERS
118AtelectasisFAERS: 1US FAERS
119Bacterial antigen positiveFAERS: 1US FAERS
120Bacterial test positiveFAERS: 1US FAERS
121Blast cell count increasedFAERS: 1US FAERS
122Blood cortisol abnormalFAERS: 1US FAERS
123Blood cortisol decreasedFAERS: 1US FAERS
124Blood potassium decreasedFAERS: 1US FAERS
125Blood urea nitrogen/creatinine ratio increasedFAERS: 1US FAERS
126Bone density decreasedFAERS: 1US FAERS
127Bronchopulmonary DysplasiaFAERS: 19097827
11745009		CTD
US FAERS
128BronchospasmFAERS: 1US FAERS
129CSF bacteria identifiedFAERS: 1US FAERS
130Cardiac ventricular thrombosisFAERS: 1US FAERS
131CellulitisFAERS: 1US FAERS
132Cerebral disorderFAERS: 1US FAERS
133Cerebrovascular accidentFAERS: 1US FAERS
134ChillsFAERS: 1US FAERS
135Congenital pneumoniaFAERS: 1US FAERS
136CraniectomyFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
137Culture urine positiveFAERS: 1US FAERS
138Cytomegalovirus enterocolitisFAERS: 1US FAERS
139Dark circles under eyesFAERS: 1US FAERS
140Diabetes mellitus inadequate controlFAERS: 1US FAERS
141Diabetic KetoacidosisFAERS: 1US FAERS
142Disease ProgressionFAERS: 1US FAERS
143Drug abuserFAERS: 1US FAERS
144Drug administration errorFAERS: 1US FAERS
145Drug effective for unapproved indicationFAERS: 1US FAERS
146Drug label confusionFAERS: 1US FAERS
147Drug prescribing errorFAERS: 1US FAERS
148Ear, nose and throat examination abnormalFAERS: 1US FAERS
149EczemaFAERS: 1US FAERS
150Enterococcal infectionFAERS: 1US FAERS
151EpididymitisFAERS: 1US FAERS
152EpistaxisFAERS: 1US FAERS
153Escherichia infectionFAERS: 1US FAERS
154Expired drug administeredFAERS: 1US FAERS
155Eye painFAERS: 1US FAERS
156Failure to suspend medicationFAERS: 1US FAERS
157Fat necrosisFAERS: 1US FAERS
158Feeding disorder of infancy OR early childhoodFAERS: 1US FAERS
159Feeling ColdFAERS: 1US FAERS
160Feeling abnormalFAERS: 1US FAERS
161Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
162Gastric fluid analysis abnormalFAERS: 1US FAERS
163Gastric ulcerFAERS: 1US FAERS
164GastroenteritisFAERS: 1US FAERS
165Gastrointestinal motility disorderFAERS: 1US FAERS
166General physical health deteriorationFAERS: 1US FAERS
167GlaucomaFAERS: 1US FAERS
168Growth retardationFAERS: 1US FAERS
169Hormone level abnormalFAERS: 1US FAERS
170HydropneumothoraxFAERS: 1US FAERS
171HypersomniaFAERS: 1US FAERS
172HyperventilationFAERS: 1US FAERS
173HypotensionFAERS: 1US FAERS
174HypoxiaFAERS: 1US FAERS
175Iatrogenic injuryFAERS: 1US FAERS
176ImmunosuppressionFAERS: 1US FAERS
177Impaired driving abilityFAERS: 1US FAERS
178Impaired work abilityFAERS: 1US FAERS
179ImpatienceFAERS: 1US FAERS
180Inappropriate schedule of drug administrationFAERS: 1US FAERS
181Incision site infectionFAERS: 1US FAERS
182IncontinenceFAERS: 1US FAERS
183Incorrect drug administration durationFAERS: 1US FAERS
184InfluenzaFAERS: 1US FAERS
185Injected limb mobility decreasedFAERS: 1US FAERS
186Injection site nerve damageFAERS: 1US FAERS
187Injection site noduleFAERS: 1US FAERS
188Injury associated with deviceFAERS: 1US FAERS
189Intermittent ClaudicationFAERS: 1US FAERS
190Intra-abdominal fluid collectionFAERS: 1US FAERS
191Irritable Bowel SyndromeFAERS: 1US FAERS
192Joint injuryFAERS: 1US FAERS
193KeratitisFAERS: 1US FAERS
194Laryngeal ObstructionFAERS: 1US FAERS
195LeukocytosisFAERS: 1US FAERS
196Live BirthFAERS: 1US FAERS
197LymphadenopathyFAERS: 1US FAERS
198Memory impairmentFAERS: 1US FAERS
199Mood swingsFAERS: 1US FAERS
200Musculoskeletal stiffnessFAERS: 1US FAERS
201MydriasisFAERS: 1US FAERS
202MyopathyFAERS: 1US FAERS
203Neonatal disorderFAERS: 1US FAERS
204Neonatal tachycardiaFAERS: 1US FAERS
205No reaction on previous exposure to drugFAERS: 1US FAERS
206Nuchal RigidityFAERS: 1US FAERS
207OligohydramniosFAERS: 1US FAERS
208OphthalmoplegiaFAERS: 1US FAERS
209Orbital apex syndromeFAERS: 1US FAERS
210OrchitisFAERS: 1US FAERS
211Oropharyngeal painFAERS: 1US FAERS
212OsteomyelitisFAERS: 1US FAERS
213OsteoporosisFAERS: 1US FAERS
214OverdoseFAERS: 1US FAERS
215PallorFAERS: 1US FAERS
216Pancreatic enlargementFAERS: 1US FAERS
217PancreatitisFAERS: 1US FAERS
218Patent ductus arteriosusFAERS: 1US FAERS
219PeritonitisFAERS: 1US FAERS
220Personality ChangeFAERS: 1US FAERS
221Pharyngolaryngeal PainFAERS: 1US FAERS
222Pharyngolaryngeal discomfortFAERS: 1US FAERS
223PhotophobiaFAERS: 1US FAERS
224PleurisyFAERS: 1US FAERS
225Pneumocystis jiroveci pneumoniaFAERS: 1US FAERS
226PneumoniaFAERS: 1US FAERS
227PneumothoraxFAERS: 1US FAERS
228PolyhydramniosFAERS: 1US FAERS
229Poor quality drug administeredFAERS: 1US FAERS
230Post procedural painFAERS: 1US FAERS
231Product container issueFAERS: 1US FAERS
232Product contamination microbialFAERS: 1US FAERS
233Product dosage form issueFAERS: 1US FAERS
234Product label confusionFAERS: 1US FAERS
235Product physical issueFAERS: 1US FAERS
236Product use complaintFAERS: 1US FAERS
237Pulmonary arterial pressure abnormalFAERS: 1US FAERS
238Pulmonary necrosisFAERS: 1US FAERS
239Quality of life decreasedFAERS: 1US FAERS
240RadiculopathyFAERS: 1US FAERS
241Rash erythematousFAERS: 1SIDER
US FAERS
242Refusal of treatment by relativeFAERS: 1US FAERS
243SepsisFAERS: 1US FAERS
244SinusitisFAERS: 1US FAERS
245Skin lacerationFAERS: 1US FAERS
246SpondylolysisFAERS: 1US FAERS
247Stevens-Johnson SyndromeFAERS: 1US FAERS
248StridorFAERS: 1US FAERS
249Subcutaneous noduleFAERS: 1US FAERS
250Sudden deathFAERS: 1US FAERS
251Suspected transmission of an infectious agent via productFAERS: 1US FAERS
252SyncopeFAERS: 1US FAERS
253TachycardiaFAERS: 1US FAERS
254TalipesFAERS: 1US FAERS
255Therapeutic response unexpectedFAERS: 1US FAERS
256ThirstFAERS: 1US FAERS
257TinnitusFAERS: 1US FAERS
258TracheitisFAERS: 1US FAERS
259Transaminases increasedFAERS: 1US FAERS
260TremorFAERS: 1US FAERS
261Tympanic Membrane PerforationFAERS: 1US FAERS
262Ultrasound Doppler abnormalFAERS: 1US FAERS
263VertigoFAERS: 1US FAERS
264Weight decreasedFAERS: 1US FAERS
265Wrong drug administeredFAERS: 1US FAERS
266Wrong technique in product usage processFAERS: 1US FAERS
267Acidosis4052188
19249894		CTD
268Acne Vulgaris4241782CTD
269Arthritis, Experimental21717043CTD
270Asthenozoospermia27132128CTD
271Birth Weight28887130CTD
272Dermatitis, Allergic Contact11692113CTD
273Dermatitis, Atopic11692113CTD
274Dermatitis8273557CTD
SIDER
275Drug Eruptions4241782
4278287		CTD
276Dry skinSIDER
277Duodenal UlcerCanada Vigilance: 1Canada Vigilance
278Dysarthria16830158CTD
279Dysphonia12235614CTD
280EcchymosisCanada Vigilance: 1Canada Vigilance
281Edema8273557CTD
282Eosinophilia8535097CTD
283Eyelid Neoplasms15107744CTD
284Fetal Growth Retardation14662159CTD
285FolliculitisSIDER
286Friedreich Ataxia23418481CTD
287GlycosuriaSIDER
288Heart failure6108879CTD
289Hemangioma15107744CTD
290Hyperemia16156157CTD
291Hyperglycemia19249894CTD
292HypertrichosisSIDER
293Hypokalemia19249894
21252779		CTD
294Hypokalemic periodic paralysis21252779CTD
295Hypophosphatemia16830158CTD
296Injection site inflammationCanada Vigilance: 1Canada Vigilance
297Insulin Resistance15924982CTD
298Joint stiffnessCanada Vigilance: 1Canada Vigilance
299LeukodermaSIDER
300Leukomalacia, Periventricular12369299CTD
301Loss of skin markingsSIDER
302Low Back Pain12235614CTD
303MiliariaSIDER
304Muscle Weakness16830158
21252779		CTD
305Myocardial Infarction8629796CTD
306Myoclonus10955182CTD
307Necrosis16156157CTD
308Ocular Hypertension9435188CTD
309Olfaction Disorders1932926CTD
310PapuleSIDER
311Paraplegia19863744CTD
312Peripheral Nervous System Diseases2636374CTD
313Pre-Eclampsia8193107CTD
314Pregnancy Complications21252779CTD
315Prenatal Exposure Delayed Effects

View details

10362077
15924982
19047579
27132128
28887130
29953847
 		CTD
316Pseudotumor Cerebri16391461CTD
317Psoriasis851765CTD
318Pulmonary Edema6108879
19249894		CTD
319Pustular psoriasisSIDER
320Quadriplegia2636374CTD
321Rash follicularSIDER
322Renal Insufficiency19249894CTD
323Respiration Disorders2636374CTD
324Respiratory Distress Syndrome, Newborn15924982CTD
325Respiratory Tract Infections19624990CTD
326RhinitisCanada Vigilance: 1Canada Vigilance
327Spinal Cord Diseases19863744CTD
328Tauopathies16930453CTD
329Telangiectasis3888708
4237682		CTD
330Tietze's Syndrome16830158CTD
331TuberculosisCanada Vigilance: 1Canada Vigilance
332Ventricular Outflow Obstruction9097827CTD
333anaphylaxis8629796CTD
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