Duloxetine Hydrochloride
(BFFSMCNJSOPUAY-LMOVPXPDSA-N)
Structure
- SMILES
- CNCC[C@@H](c1cccs1)Oc1cccc2c1cccc2.Cl
- Molecular Formula:
- C18H20ClNOS
- Molecular Weight:
- 333.876
- Log P:
- 5.8238
- Hydrogen Bond Acceptor:
- 3
- Hydrogen Bond Donor:
- 2
- TPSA:
- 49.5
- CAS Number(s):
- 136434-34-9
Synonym(s)
1.
Duloxetine Hydrochloride
2.
Cymbalta
3.
Duloxetine
4.
Duloxetine Ethanedioate (1:1), (+-)-isomer - T353987
5.
Duloxetine HCl
6.
Duloxetine, (+)-isomer
7.
LY 227942
8.
LY 248686
9.
LY-227942
10.
LY-248686
11.
LY227942
12.
N-methyl-3-(1-naphthalenyloxy)-2-thiophenepropanamine
13.
N-methyl-3-(1-naphthalenyloxy)-3-(2-thiophene)propanamide
14.
HCl, Duloxetine
15.
Hydrochloride, Duloxetine
16.
LY248686
External Link(s)
| MeSH | D000068736 |
| PubChem Compound | 11966296 60834 57515987 |
| ChEBI | 31526 |
| CHEMBL | CHEMBL1200328 |
| KEGG | dr:D01179 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug withdrawal syndrome | FAERS: 63 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 2 | Nausea | FAERS: 63 Canada Vigilance: 4 | 17288694 20199139 | CTD Canada Vigilance US FAERS |
| 3 | Dizziness | FAERS: 61 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 4 | Anxiety | FAERS: 57 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 5 | Headache | FAERS: 54 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 6 | Drug ineffective | FAERS: 50 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 7 | Product substitution issue | FAERS: 50 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 8 | Feeling abnormal | FAERS: 42 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 9 | Pain | FAERS: 39 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 10 | Tremor | FAERS: 31 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 11 | Vomiting | FAERS: 28 Canada Vigilance: 6 | 17288694 | CTD Canada Vigilance US FAERS |
| 12 | Crying | FAERS: 27 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 13 | Fatigue | FAERS: 27 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 14 | Alanine Aminotransferase Increased | FAERS: 23 | US FAERS | |
| 15 | Malaise | FAERS: 19 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Asthenia | FAERS: 17 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 17 | Somnolence | FAERS: 16 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 18 | Aspartate Aminotransferase Increased | FAERS: 15 | US FAERS | |
| 19 | Palpitations | FAERS: 15 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 20 | Mood swings | FAERS: 12 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Chills | FAERS: 11 | US FAERS | |
| 22 | Product quality issue | FAERS: 11 | US FAERS | |
| 23 | Pruritus | FAERS: 11 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 24 | Syncope | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 25 | Urinary Retention | FAERS: 11 Canada Vigilance: 1 | 21177420 | CTD Canada Vigilance US FAERS |
| 26 | Constipation | FAERS: 10 Canada Vigilance: 1 | 15589385 | CTD Canada Vigilance US FAERS |
| 27 | Drug dose omission | FAERS: 10 | US FAERS | |
| 28 | Intentional product misuse | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 29 | Memory impairment | FAERS: 10 | US FAERS | |
| 30 | Agitation | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 31 | Anger | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Maternal exposure during pregnancy | FAERS: 9 | US FAERS | |
| 33 | Nervousness | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 34 | Wrong technique in product usage process | FAERS: 9 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 35 | Depressed mood | FAERS: 8 | US FAERS | |
| 36 | Fibromyalgia | FAERS: 8 | 19835639 | CTD US FAERS |
| 37 | Gamma-Glutamyltransferase Increased | FAERS: 8 | US FAERS | |
| 38 | Hypersensitivity | FAERS: 8 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 39 | Toxicity to various agents | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 40 | Weight decreased | FAERS: 8 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 41 | Chest Pain | FAERS: 7 Canada Vigilance: 1 | 19193339 | CTD Canada Vigilance US FAERS |
| 42 | Head discomfort | FAERS: 7 | US FAERS | |
| 43 | Myalgia | FAERS: 7 | US FAERS | |
| 44 | Restlessness | FAERS: 7 | US FAERS | |
| 45 | Urinary tract infection | FAERS: 7 | US FAERS | |
| 46 | Vertigo | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 47 | Alopecia | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 48 | Disorientation | FAERS: 6 | US FAERS | |
| 49 | Emotional disorder | FAERS: 6 | US FAERS | |
| 50 | Impaired work ability | FAERS: 6 | US FAERS | |
| 51 | Maternal exposure during breast feeding | FAERS: 6 | US FAERS | |
| 52 | Serotonin Syndrome | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 53 | Trismus | FAERS: 6 | US FAERS | |
| 54 | Visual Impairment | FAERS: 6 | US FAERS | |
| 55 | Abdominal Pain | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 56 | Amnesia | FAERS: 5 | US FAERS | |
| 57 | Arthralgia | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 58 | Burning sensation | FAERS: 5 | US FAERS | |
| 59 | Cerebral Infarction | FAERS: 5 | US FAERS | |
| 60 | Chest discomfort | FAERS: 5 | US FAERS | |
| 61 | Feeling jittery | FAERS: 5 | US FAERS | |
| 62 | Hypertensive crisis | FAERS: 5 | US FAERS | |
| 63 | Lethargy | FAERS: 5 | US FAERS | |
| 64 | Overdose | FAERS: 5 | US FAERS | |
| 65 | Pulmonary Embolism | FAERS: 5 | US FAERS | |
| 66 | Suicide attempt | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 67 | Abdominal discomfort | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 68 | Apathy | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 69 | Cerebrovascular accident | FAERS: 4 | US FAERS | |
| 70 | Completed Suicide | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 71 | Conversion disorder | FAERS: 4 | US FAERS | |
| 72 | Discomfort | FAERS: 4 | US FAERS | |
| 73 | Drug dispensing error | FAERS: 4 | US FAERS | |
| 74 | Exposure via breast milk | FAERS: 4 | US FAERS | |
| 75 | Hepatotoxicity | FAERS: 4 | US FAERS | |
| 76 | Hypotension | FAERS: 4 | US FAERS | |
| 77 | Incorrect dose administered | FAERS: 4 | US FAERS | |
| 78 | Intentional drug misuse | FAERS: 4 | US FAERS | |
| 79 | Intentional self-injury | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 80 | Neuroleptic Malignant Syndrome | FAERS: 4 | US FAERS | |
| 81 | No adverse event | FAERS: 4 | US FAERS | |
| 82 | Pallor | FAERS: 4 | US FAERS | |
| 83 | Poisoning | FAERS: 4 | US FAERS | |
| 84 | Stress | FAERS: 4 | US FAERS | |
| 85 | Tachyphrenia | FAERS: 4 | US FAERS | |
| 86 | jaundice | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 87 | Activities of daily living impaired | FAERS: 3 | US FAERS | |
| 88 | Adverse event | FAERS: 3 | US FAERS | |
| 89 | Akathisia | FAERS: 3 | US FAERS | |
| 90 | Back Pain | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 91 | Blood creatine phosphokinase increased | FAERS: 3 | US FAERS | |
| 92 | Bradycardia | FAERS: 3 | US FAERS | |
| 93 | Cervix carcinoma | FAERS: 3 | US FAERS | |
| 94 | Cold sweat | FAERS: 3 | US FAERS | |
| 95 | Compression fracture | FAERS: 3 | US FAERS | |
| 96 | Creatinine renal clearance decreased | FAERS: 3 | US FAERS | |
| 97 | Drug abuse | FAERS: 3 | US FAERS | |
| 98 | Dyslexia | FAERS: 3 | US FAERS | |
| 99 | Dyspepsia | FAERS: 3 | US FAERS | |
| 100 | Dystonia | FAERS: 3 | US FAERS | |
| 101 | Epilepsy | FAERS: 3 | US FAERS | |
| 102 | Erythema | FAERS: 3 | US FAERS | |
| 103 | Exposure during breast feeding | FAERS: 3 | US FAERS | |
| 104 | Food craving | FAERS: 3 | US FAERS | |
| 105 | Hemiparesis | FAERS: 3 | US FAERS | |
| 106 | Hypertensive Encephalopathy | FAERS: 3 | US FAERS | |
| 107 | Intestinal Obstruction | FAERS: 3 | US FAERS | |
| 108 | Lower respiratory tract infection | FAERS: 3 | US FAERS | |
| 109 | Musculoskeletal stiffness | FAERS: 3 | US FAERS | |
| 110 | Myocardial Infarction | FAERS: 3 | US FAERS | |
| 111 | Panic Disorder | FAERS: 3 | 20663271 | CTD US FAERS |
| 112 | Paranoia | FAERS: 3 | US FAERS | |
| 113 | Pelvic mass | FAERS: 3 | US FAERS | |
| 114 | Pneumonia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 115 | Presyncope | FAERS: 3 | US FAERS | |
| 116 | Pulmonary Hypertension | FAERS: 3 | US FAERS | |
| 117 | Stevens-Johnson Syndrome | FAERS: 3 Canada Vigilance: 1 | 25811541 | CTD Canada Vigilance US FAERS |
| 118 | Tachycardia | FAERS: 3 | 18728105 | CTD US FAERS |
| 119 | Urticaria | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 120 | Wrong technique in drug usage process | FAERS: 3 | US FAERS | |
| 121 | Arthritis | FAERS: 2 | US FAERS | |
| 122 | Blood chloride decreased | FAERS: 2 | US FAERS | |
| 123 | Blood glucose increased | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 124 | Boredom | FAERS: 2 | US FAERS | |
| 125 | Bradyphrenia | FAERS: 2 | US FAERS | |
| 126 | Brain stem syndrome | FAERS: 2 | US FAERS | |
| 127 | Cataract | FAERS: 2 | US FAERS | |
| 128 | Cholelithiasis | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 129 | Congenital hydronephrosis | FAERS: 2 | US FAERS | |
| 130 | Cyclothymic Disorder | FAERS: 2 | US FAERS | |
| 131 | Cytolytic hepatitis | FAERS: 2 | US FAERS | |
| 132 | Dehydration | FAERS: 2 | US FAERS | |
| 133 | Diplopia | FAERS: 2 | US FAERS | |
| 134 | Dysarthria | FAERS: 2 | US FAERS | |
| 135 | Dysuria | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 136 | Emotional distress | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 137 | Eosinophilic Pneumonia | FAERS: 2 | US FAERS | |
| 138 | Euphoric mood | FAERS: 2 | US FAERS | |
| 139 | Extra dose administered | FAERS: 2 | US FAERS | |
| 140 | Feeling Cold | FAERS: 2 | US FAERS | |
| 141 | Gait inability | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 142 | Gestational Diabetes | FAERS: 2 | US FAERS | |
| 143 | Hepatitis | FAERS: 2 | US FAERS | |
| 144 | Hyperreflexia | FAERS: 2 | US FAERS | |
| 145 | Hypomania | FAERS: 2 | US FAERS | |
| 146 | Hypophagia | FAERS: 2 | US FAERS | |
| 147 | Initial insomnia | FAERS: 2 | US FAERS | |
| 148 | Keratitis | FAERS: 2 | US FAERS | |
| 149 | Locked-In Syndrome | FAERS: 2 | US FAERS | |
| 150 | Malignant neoplasm progression | FAERS: 2 | US FAERS | |
| 151 | Maternal exposure before pregnancy | FAERS: 2 | US FAERS | |
| 152 | Mental impairment | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 153 | Mental status changes | FAERS: 2 | US FAERS | |
| 154 | Nasopharyngitis | FAERS: 2 | US FAERS | |
| 155 | Poor personal hygiene | FAERS: 2 | US FAERS | |
| 156 | Poor sucking reflex | FAERS: 2 | US FAERS | |
| 157 | Product dispensing error | FAERS: 2 | US FAERS | |
| 158 | Product physical issue | FAERS: 2 | US FAERS | |
| 159 | Psychiatric symptom | FAERS: 2 | US FAERS | |
| 160 | Purpura | FAERS: 2 | US FAERS | |
| 161 | Septic Shock | FAERS: 2 | US FAERS | |
| 162 | Sinus Tachycardia | FAERS: 2 | US FAERS | |
| 163 | Starvation | FAERS: 2 | US FAERS | |
| 164 | Stomatitis | FAERS: 2 | US FAERS | |
| 165 | Talipes | FAERS: 2 | US FAERS | |
| 166 | Tardive Dyskinesia | FAERS: 2 | US FAERS | |
| 167 | Thirst | FAERS: 2 | US FAERS | |
| 168 | Unevaluable event | FAERS: 2 | US FAERS | |
| 169 | Urinary Incontinence | FAERS: 2 | US FAERS | |
| 170 | Wheezing | FAERS: 2 | US FAERS | |
| 171 | Wound infection staphylococcal | FAERS: 2 | US FAERS | |
| 172 | Abasia | FAERS: 1 | US FAERS | |
| 173 | Abnormal weight gain | FAERS: 1 | US FAERS | |
| 174 | Accidental overdose | FAERS: 1 | US FAERS | |
| 175 | Activation syndrome | FAERS: 1 | US FAERS | |
| 176 | Acute Coronary Syndrome | FAERS: 1 | US FAERS | |
| 177 | Acute hepatitis C | FAERS: 1 | US FAERS | |
| 178 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 179 | Agitated depression | FAERS: 1 | US FAERS | |
| 180 | Alanine aminotransferase abnormal | FAERS: 1 | US FAERS | |
| 181 | Alcohol Intolerance | FAERS: 1 | US FAERS | |
| 182 | Alcohol poisoning | FAERS: 1 | US FAERS | |
| 183 | Altered state of consciousness | FAERS: 1 | US FAERS | |
| 184 | Ammonia increased | FAERS: 1 | US FAERS | |
| 185 | Amyotrophic Lateral Sclerosis | FAERS: 1 | US FAERS | |
| 186 | Anhedonia | FAERS: 1 | US FAERS | |
| 187 | Aphasia | FAERS: 1 | US FAERS | |
| 188 | Asthma | FAERS: 1 | US FAERS | |
| 189 | Autonomic nervous system imbalance | FAERS: 1 | US FAERS | |
| 190 | Biliary Colic | FAERS: 1 | US FAERS | |
| 191 | Bilirubin conjugated increased | FAERS: 1 | US FAERS | |
| 192 | Bipolar Disorder | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 193 | Bipolar I disorder | FAERS: 1 | US FAERS | |
| 194 | Blindness | FAERS: 1 | US FAERS | |
| 195 | Blood albumin increased | FAERS: 1 | US FAERS | |
| 196 | Blood alkaline phosphatase increased | FAERS: 1 | US FAERS | |
| 197 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 198 | Blood electrolytes decreased | FAERS: 1 | US FAERS | |
| 199 | Blood fibrinogen abnormal | FAERS: 1 | US FAERS | |
| 200 | Blood glucose abnormal | FAERS: 1 | US FAERS | |
| 201 | Blood immunoglobulin M abnormal | FAERS: 1 | US FAERS | |
| 202 | Blood pressure fluctuation | FAERS: 1 | US FAERS | |
| 203 | Blood thyroid stimulating hormone increased | FAERS: 1 | US FAERS | |
| 204 | Blood triglycerides increased | FAERS: 1 | US FAERS | |
| 205 | Blood urea increased | FAERS: 1 | US FAERS | |
| 206 | Bone pain | FAERS: 1 | US FAERS | |
| 207 | Borderline Personality Disorder | FAERS: 1 | US FAERS | |
| 208 | Bronchopneumonia | FAERS: 1 | US FAERS | |
| 209 | Cardiac dysfunction | FAERS: 1 | US FAERS | |
| 210 | Cerebral disorder | FAERS: 1 | US FAERS | |
| 211 | Charles Bonnet Syndrome | FAERS: 1 | US FAERS | |
| 212 | Cheilitis | FAERS: 1 | US FAERS | |
| 213 | Cholangiocarcinoma | FAERS: 1 | US FAERS | |
| 214 | Chromaturia | FAERS: 1 | US FAERS | |
| 215 | Cycloplegia | FAERS: 1 | US FAERS | |
| 216 | Deafness | FAERS: 1 | US FAERS | |
| 217 | Delirium | FAERS: 1 | US FAERS | |
| 218 | Delusional perception | FAERS: 1 | US FAERS | |
| 219 | Dementia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 220 | Depression suicidal | FAERS: 1 | US FAERS | |
| 221 | Diet refusal | FAERS: 1 | US FAERS | |
| 222 | Disease recurrence | FAERS: 1 | US FAERS | |
| 223 | Dissociation | FAERS: 1 | US FAERS | |
| 224 | Drug level above therapeutic | FAERS: 1 | US FAERS | |
| 225 | Drug level increased | FAERS: 1 | US FAERS | |
| 226 | Drug toxicity | FAERS: 1 | US FAERS | |
| 227 | Drug withdrawal headache | FAERS: 1 | US FAERS | |
| 228 | Dry skin | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 229 | Economic problem | FAERS: 1 | US FAERS | |
| 230 | Electrocardiogram abnormal | FAERS: 1 | US FAERS | |
| 231 | Electrocardiogram change | FAERS: 1 | US FAERS | |
| 232 | Electrolyte imbalance | FAERS: 1 | US FAERS | |
| 233 | Emotional poverty | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 234 | Encephalitis | FAERS: 1 | US FAERS | |
| 235 | Epigastric discomfort | FAERS: 1 | US FAERS | |
| 236 | Epinephrine increased | FAERS: 1 | US FAERS | |
| 237 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 238 | Eye pain | FAERS: 1 | US FAERS | |
| 239 | Feelings of worthlessness | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 240 | Flat affect | FAERS: 1 | US FAERS | |
| 241 | Flatulence | FAERS: 1 | US FAERS | |
| 242 | Flushing | FAERS: 1 | US FAERS | |
| 243 | Fracture | FAERS: 1 | US FAERS | |
| 244 | General physical condition abnormal | FAERS: 1 | US FAERS | |
| 245 | Gingivitis | FAERS: 1 | US FAERS | |
| 246 | Glossitis | FAERS: 1 | US FAERS | |
| 247 | Guillain-Barre Syndrome | FAERS: 1 | US FAERS | |
| 248 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 249 | Hunger | FAERS: 1 | US FAERS | |
| 250 | Hyperthyroidism | FAERS: 1 | US FAERS | |
| 251 | Hyperventilation | FAERS: 1 | US FAERS | |
| 252 | Hypervigilance | FAERS: 1 | US FAERS | |
| 253 | Hypokinesia | FAERS: 1 | US FAERS | |
| 254 | Hypoplastic Left Heart Syndrome | FAERS: 1 | US FAERS | |
| 255 | Hypothyroidism | FAERS: 1 | US FAERS | |
| 256 | Idiosyncratic drug reaction | FAERS: 1 | US FAERS | |
| 257 | Impaired driving ability | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 258 | Impaired self-care | FAERS: 1 | US FAERS | |
| 259 | Impatience | FAERS: 1 | US FAERS | |
| 260 | Inappropriate schedule of drug administration | FAERS: 1 | US FAERS | |
| 261 | Incontinence | FAERS: 1 | US FAERS | |
| 262 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 263 | Incorrect route of product administration | FAERS: 1 | US FAERS | |
| 264 | Infection | FAERS: 1 | US FAERS | |
| 265 | Influenza | FAERS: 1 | US FAERS | |
| 266 | Intercepted product dispensing error | FAERS: 1 | US FAERS | |
| 267 | Intervertebral Disc Degeneration | FAERS: 1 | US FAERS | |
| 268 | Joint injury | FAERS: 1 | US FAERS | |
| 269 | Joint stiffness | FAERS: 1 | US FAERS | |
| 270 | Joint swelling | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 271 | Laceration | FAERS: 1 | US FAERS | |
| 272 | Leukopenia | FAERS: 1 | US FAERS | |
| 273 | Libido disorder | FAERS: 1 | US FAERS | |
| 274 | Limb discomfort | FAERS: 1 | US FAERS | |
| 275 | Lip and/or oral cavity cancer | FAERS: 1 | US FAERS | |
| 276 | Lip swelling | FAERS: 1 | US FAERS | |
| 277 | Meningitis | FAERS: 1 | US FAERS | |
| 278 | Morbid thoughts | FAERS: 1 | US FAERS | |
| 279 | Multiple drug overdose intentional | FAERS: 1 | US FAERS | |
| 280 | Muscle tightness | FAERS: 1 | US FAERS | |
| 281 | Musculoskeletal discomfort | FAERS: 1 | US FAERS | |
| 282 | Mydriasis | FAERS: 1 | US FAERS | |
| 283 | Nail picking | FAERS: 1 | US FAERS | |
| 284 | Neck Pain | FAERS: 1 | US FAERS | |
| 285 | Neonatal disorder | FAERS: 1 | US FAERS | |
| 286 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 287 | Nephrotic Syndrome | FAERS: 1 | US FAERS | |
| 288 | Neuralgia | FAERS: 1 | US FAERS | |
| 289 | Night sweats | FAERS: 1 | US FAERS | |
| 290 | Obsessive-Compulsive Disorder | FAERS: 1 | US FAERS | |
| 291 | Opiates positive | FAERS: 1 | US FAERS | |
| 292 | Optic Neuritis | FAERS: 1 | US FAERS | |
| 293 | Oral contusion | FAERS: 1 | US FAERS | |
| 294 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 295 | Osteomyelitis | FAERS: 1 | US FAERS | |
| 296 | Pancreatic enzymes increased | FAERS: 1 | US FAERS | |
| 297 | Pancreatitis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 298 | Paraplegia | FAERS: 1 | US FAERS | |
| 299 | Partner stress | FAERS: 1 | US FAERS | |
| 300 | Pericardial effusion | FAERS: 1 | US FAERS | |
| 301 | Periorbital disorder | FAERS: 1 | US FAERS | |
| 302 | Personality Change | FAERS: 1 | US FAERS | |
| 303 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 304 | Photophobia | FAERS: 1 | US FAERS | |
| 305 | Pilonidal Cyst | FAERS: 1 | US FAERS | |
| 306 | Plantar erythema | FAERS: 1 | US FAERS | |
| 307 | Polyuria | FAERS: 1 | US FAERS | |
| 308 | Poor peripheral circulation | FAERS: 1 | US FAERS | |
| 309 | Post lumbar puncture syndrome | FAERS: 1 | US FAERS | |
| 310 | Post procedural complication | FAERS: 1 | US FAERS | |
| 311 | Post-Traumatic Stress Disorder | FAERS: 1 | US FAERS | |
| 312 | Priapism | FAERS: 1 | US FAERS | |
| 313 | Product appearance confusion | FAERS: 1 | US FAERS | |
| 314 | Product dose omission | FAERS: 1 | US FAERS | |
| 315 | Product formulation issue | FAERS: 1 | US FAERS | |
| 316 | Product packaging issue | FAERS: 1 | US FAERS | |
| 317 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 318 | Rash erythematous | FAERS: 1 | US FAERS | |
| 319 | Respiratory distress | FAERS: 1 | US FAERS | |
| 320 | Restless Legs Syndrome | FAERS: 1 Canada Vigilance: 1 | 18468624 | CTD Canada Vigilance US FAERS |
| 321 | Screaming | FAERS: 1 | US FAERS | |
| 322 | Separation Anxiety Disorder | FAERS: 1 | US FAERS | |
| 323 | Sleep disorder due to general medical condition, insomnia type | FAERS: 1 | US FAERS | |
| 324 | Somnambulism | FAERS: 1 | US FAERS | |
| 325 | Sopor | FAERS: 1 | US FAERS | |
| 326 | Staphylococcal Scalded Skin Syndrome | FAERS: 1 | US FAERS | |
| 327 | Subileus | FAERS: 1 | US FAERS | |
| 328 | Sudden death | FAERS: 1 | US FAERS | |
| 329 | Sunburn | FAERS: 1 | US FAERS | |
| 330 | Suspected counterfeit product | FAERS: 1 | US FAERS | |
| 331 | Swelling | FAERS: 1 | US FAERS | |
| 332 | Temperature regulation disorder | FAERS: 1 | US FAERS | |
| 333 | Tension Headache | FAERS: 1 | US FAERS | |
| 334 | Therapeutic response changed | FAERS: 1 | US FAERS | |
| 335 | Therapeutic response unexpected with drug substitution | FAERS: 1 | US FAERS | |
| 336 | Therapy change | FAERS: 1 | US FAERS | |
| 337 | Tinnitus | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 338 | Tooth Loss | FAERS: 1 | US FAERS | |
| 339 | Transcription medication error | FAERS: 1 | US FAERS | |
| 340 | Unresponsive to stimuli | FAERS: 1 | US FAERS | |
| 341 | Urinary hesitation | FAERS: 1 | US FAERS | |
| 342 | Urine flow decreased | FAERS: 1 | US FAERS | |
| 343 | Vasculitis | FAERS: 1 | US FAERS | |
| 344 | Ventricular arrhythmia | FAERS: 1 | US FAERS | |
| 345 | Violence-related symptom | FAERS: 1 | US FAERS | |
| 346 | White blood cell count decreased | FAERS: 1 | US FAERS | |
| 347 | Yawning | FAERS: 1 | US FAERS | |
| 348 | nervous system disorder | FAERS: 1 | US FAERS | |
| 349 | prostatitis | FAERS: 1 | US FAERS | |
| 350 | Acne | Canada Vigilance: 1 | Canada Vigilance | |
| 351 | Benign neoplasm of adrenal gland | Canada Vigilance: 1 | Canada Vigilance | |
| 352 | Blood sodium decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 353 | Bruxism | Canada Vigilance: 1 | Canada Vigilance | |
| 354 | Depressive disorder | 17288694 19435583 | CTD | |
| 355 | Diarrhea | 15589385 | CTD | |
| 356 | Dyssomnias | 15589385 | CTD | |
| 357 | Dysthymic Disorder | 17606668 | CTD | |
| 358 | Enzyme level increased | Canada Vigilance: 1 | Canada Vigilance | |
| 359 | Erythema Multiforme | Canada Vigilance: 1 | Canada Vigilance | |
| 360 | Facial Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 361 | Feeling of body temperature change | Canada Vigilance: 1 | Canada Vigilance | |
| 362 | Female sexual arousal disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 363 | Galactorrhea-Hyperprolactinemia | 17606668 | CTD | |
| 364 | Genital discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 365 | Hyperalgesia | 18400411 20439438 | CTD | |
| 366 | Jaundice, Obstructive | 16797245 | CTD | |
| 367 | Liver Failure, Acute | 16797245 | CTD | |
| 368 | Lysosomal Storage Diseases | 28551711 | CTD | |
| 369 | Multiple Sclerosis | Canada Vigilance: 1 | Canada Vigilance | |
| 370 | Myoclonus | 19435583 | CTD | |
| 371 | Oral mucosal exfoliation | Canada Vigilance: 1 | Canada Vigilance | |
| 372 | Perforated ulcer | Canada Vigilance: 1 | Canada Vigilance | |
| 373 | Peripheral swelling | Canada Vigilance: 2 | Canada Vigilance | |
| 374 | Renal Insufficiency | 20199139 | CTD | |
| 375 | Seizures | 19435583 | CTD | |
| 376 | Sepsis | Canada Vigilance: 1 | Canada Vigilance | |
| 377 | Skin reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 378 | Sleep Initiation and Maintenance Disorders | 15232330 | CTD | |
| 379 | Temperature intolerance | Canada Vigilance: 1 | Canada Vigilance | |
| 380 | Therapeutic product effect decreased | Canada Vigilance: 1 | Canada Vigilance | |
| 381 | Xerostomia | 17288694 | CTD |
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