MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

gadodiamide

(HZHFFEYYPYZMNU-UHFFFAOYSA-K)

Structure

SMILES: CNC(=O)CN(CC(=O)[O-])CCN(CC(=O)[O-])CCN(CC(=O)NC)CC(=O)[O-].[Gd+3]
Type(s): Approved; Investigational
ATC code(s): V08CA03
Molecular Formula:: C16H26GdN5O8
Molecular Weight:: 573.656
Log P:: -6.5841
Hydrogen Bond Acceptor:: 13
Hydrogen Bond Donor:: 2
TPSA:: 188.31
CAS Number(s):: 131410-48-5

Synonym(s)

gadodiamide

Gd-DTPA bis-(methylamide)

Gd-DTPA-BMA

Omniscan

Omniscan Unique Softpack

External Link(s)

MeSH	C064925
PubChem Compound	153921 24847884 101673418
ChEBI	37333
DrugBank	DB00225
KEGG	dr:D04284
Therapeutic Target Database	D03EEH

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Fatigue	FAERS: 1		OFFSIDES SIDER US FAERS
2	Feeling abnormal	FAERS: 1		SIDER US FAERS
3	Nausea	FAERS: 1		SIDER US FAERS
4	Nephrogenic Systemic Fibrosis	FAERS: 1		SIDER US FAERS
5	Reaction to azo-dyes	FAERS: 1		US FAERS
6	Respiratory distress	FAERS: 1		US FAERS
7	Vomiting	FAERS: 1		SIDER US FAERS
8	Abasia			OFFSIDES
9	Abdominal Abscess			OFFSIDES
10	Abdominal Pain			SIDER
11	Abdominal discomfort			OFFSIDES
12	Abdominal wound dehiscence			OFFSIDES
13	Abnormal vision			SIDER
14	Acid reflux			OFFSIDES
15	Activities of daily living impaired			OFFSIDES
16	Acute Coronary Syndrome			SIDER
17	Acute kidney injury		11287523	CTD SIDER
18	Adenoma			OFFSIDES
19	Ageusia			SIDER
20	Agraphia			OFFSIDES
21	Alopecia		18397714	CTD OFFSIDES
22	Amputation			OFFSIDES
23	Anal Fissure			OFFSIDES
24	Anaphylactic shock			SIDER
25	Anaphylactoid Reaction			SIDER
26	Anhedonia			OFFSIDES
27	Anisocytosis			OFFSIDES
28	Antiphospholipid antibodies positive			OFFSIDES
29	Anxiety			OFFSIDES SIDER
30	Aortic embolus			OFFSIDES
31	Application site pain			SIDER
32	Arteriosclerosis			OFFSIDES
33	Arteriovenous fistula thrombosis			OFFSIDES
34	Arteriovenous fistula			OFFSIDES
35	Arteriovenous graft site abscess			OFFSIDES
36	Arthralgia			SIDER
37	Arthritis			OFFSIDES
38	Arthrofibrosis			OFFSIDES
39	Arthropathy			OFFSIDES
40	Asthenia			OFFSIDES SIDER
41	Ataxia			SIDER
42	Atelectasis			OFFSIDES
43	Autonomic neuropathy			SIDER
44	Avascular necrosis			OFFSIDES
45	Bedridden			OFFSIDES
46	Bereavement			OFFSIDES
47	Biopsy muscle abnormal			OFFSIDES
48	Blood creatinine increased			SIDER
49	Blood iron increased			OFFSIDES
50	Blood parathyroid hormone increased			OFFSIDES
51	Blood phosphorus increased			OFFSIDES
52	Bone Sarcoma			OFFSIDES
53	Bone density increased			OFFSIDES
54	Bone lesion			OFFSIDES
55	Bone pain			OFFSIDES
56	Bone scan abnormal			OFFSIDES
57	Bronchial secretion retention			OFFSIDES
58	Bronchopneumonia			OFFSIDES
59	Bronchospasm			SIDER
60	Burning sensation			OFFSIDES
61	Calcinosis			OFFSIDES
62	Calciphylaxis			OFFSIDES
63	Cardiac valve vegetation			OFFSIDES
64	Catheter related infection			OFFSIDES
65	Cellulitis			OFFSIDES
66	Cerebellar Diseases		9763378	CTD
67	Cerebral calcification			OFFSIDES
68	Cervicobrachial syndrome			OFFSIDES
69	Chest Pain			SIDER
70	Chills			SIDER
71	Clumsiness			OFFSIDES
72	Contracture			OFFSIDES
73	Contrast media allergy			OFFSIDES
74	Deaf Mutism			OFFSIDES
75	Demyelination			OFFSIDES
76	Dependence on enabling machine or device			OFFSIDES
77	Dermatitis			SIDER
78	Dermatomyositis			OFFSIDES
79	Device related infection			OFFSIDES
80	Diabetic ulcer			OFFSIDES
81	Diastolic dysfunction			OFFSIDES
82	Discomfort			SIDER
83	Disease Progression			OFFSIDES
84	Disease complication			OFFSIDES
85	Diverticulosis			OFFSIDES
86	Dizziness			SIDER
87	Drug prescribing error			OFFSIDES
88	Dry skin			OFFSIDES
89	Dysgeusia			SIDER
90	Dyspepsia			SIDER
91	Dystrophic calcification			OFFSIDES
92	Eczema			OFFSIDES
93	Emotional distress			OFFSIDES
94	Epidermal necrosis			OFFSIDES
95	Epidural Abscess			OFFSIDES
96	Eructation			SIDER
97	Erythema			OFFSIDES
98	Eschar			OFFSIDES
99	Eustachian tube disorder			OFFSIDES
100	Excoriation			OFFSIDES
101	Exfoliative rash			OFFSIDES
102	Exophthalmos			OFFSIDES
103	Extremity contracture			OFFSIDES
104	Eye excision			OFFSIDES
105	Femoral artery occlusion			OFFSIDES
106	Fibromyalgia			OFFSIDES
107	Fluid overload			OFFSIDES
108	Flushing			SIDER
109	Formication			OFFSIDES
110	Gangrene			OFFSIDES
111	Gastrointestinal Pain			SIDER
112	General physical health deterioration			OFFSIDES
113	Grip strength			OFFSIDES
114	Hay fever			OFFSIDES
115	Headache			SIDER
116	Hungry bone syndrome			OFFSIDES
117	Hyperkeratosis			OFFSIDES
118	Hyperparathyroidism			OFFSIDES
119	Hyperpigmentation			OFFSIDES
120	Hypersensitivity			SIDER
121	Hypertrophic Cardiomyopathy			OFFSIDES
122	Hypotension			SIDER
123	Immobile			OFFSIDES
124	Impaired self-care			OFFSIDES
125	Impaired work ability			OFFSIDES
126	Induration			OFFSIDES
127	Infusion site mobility decreased			OFFSIDES
128	Initial insomnia			OFFSIDES
129	Injection Site Reaction			SIDER
130	Injection site pain			SIDER
131	Instillation site pain			SIDER
132	Intervertebral Disc Degeneration			OFFSIDES
133	Intervertebral disc disorder			OFFSIDES
134	Intracranial Aneurysm			OFFSIDES
135	Joint Instability			OFFSIDES
136	Joint Range of Motion Decreased			OFFSIDES
137	Joint injury			OFFSIDES
138	Joint sprain			OFFSIDES
139	Joint stiffness			OFFSIDES
140	Keratopathy			OFFSIDES
141	Kidney Diseases		17884368	CTD
142	Left Ventricular Hypertrophy			OFFSIDES
143	Lichenification			OFFSIDES
144	Life expectancy shortened			OFFSIDES
145	Lightheadedness			SIDER
146	Limb discomfort			OFFSIDES
147	Listeriosis			OFFSIDES
148	Livedo Reticularis			OFFSIDES
149	Lupus encephalitis			OFFSIDES
150	Lymphedema			OFFSIDES
151	Malaise			SIDER
152	Malignant Hypertension			OFFSIDES
153	Mass excision			OFFSIDES
154	Metabolic acidosis			OFFSIDES
155	Metaplasia			OFFSIDES
156	Migraine aggravated			SIDER
157	Morphea			OFFSIDES
158	Multiple Sclerosis			SIDER
159	Muscle Fatigue			OFFSIDES
160	Muscle Weakness			OFFSIDES
161	Muscle fibrosis			OFFSIDES
162	Muscle tightness			OFFSIDES
163	Musculoskeletal Pain			OFFSIDES
164	Musculoskeletal chest pain			OFFSIDES
165	Musculoskeletal discomfort			OFFSIDES SIDER
166	Musculoskeletal stiffness			OFFSIDES
167	Myalgia			SIDER
168	Myocardial Infarction			SIDER
169	Myocardial fibrosis			OFFSIDES
170	Myoclonus		9763378	CTD
171	Myosclerosis			OFFSIDES
172	Nephroangiosclerosis			OFFSIDES
173	Nephrogenic Fibrosing Dermopathy		View details 17483196 17515358 17515359 18097279 18328659 18356456 18356457 18397714 18425843 19404939 20938346	CTD OFFSIDES
174	Neuralgia			OFFSIDES
175	Neurodermatitis			OFFSIDES
176	Nodule on extremity			OFFSIDES
177	Ocular icterus			OFFSIDES
178	Open wound			OFFSIDES
179	Osteomyelitis			OFFSIDES
180	Pain of skin			OFFSIDES
181	Pain		18397714	CTD OFFSIDES SIDER
182	Pancreatitis		11287523	CTD
183	Panniculitis			OFFSIDES
184	Paresis			SIDER
185	Pathogen resistance			OFFSIDES
186	Patient restraint			OFFSIDES
187	Peritoneal Dialysis			OFFSIDES
188	Peritonitis			OFFSIDES
189	Pharyngitis			SIDER
190	Physical disability			OFFSIDES
191	Pinguecula			OFFSIDES
192	Pleurisy			OFFSIDES
193	Poikilocytosis			OFFSIDES
194	Portal Hypertension			OFFSIDES
195	Portal Vein Thrombosis			OFFSIDES
196	Post inflammatory pigmentation change			OFFSIDES
197	Postoperative renal failure			OFFSIDES
198	Pruritus			SIDER
199	Psoas Abscess			OFFSIDES
200	Pulmonary Hypertension			OFFSIDES
201	Pulmonary arterial pressure increased			OFFSIDES
202	Pulmonary function test decreased			OFFSIDES
203	Pulmonary vascular disorder			OFFSIDES
204	Quality of life decreased			OFFSIDES
205	Rash erythematous			SIDER
206	Red blood cell spherocytes present			OFFSIDES
207	Red blood cell target cells present			OFFSIDES
208	Renal Artery Stenosis			OFFSIDES
209	Renal Osteodystrophy			OFFSIDES
210	Renal cyst			OFFSIDES
211	Respiratory Failure			OFFSIDES
212	Retroperitoneal fibrosis			OFFSIDES
213	Rhinitis			SIDER
214	Scab			OFFSIDES
215	Sclerema			OFFSIDES
216	Sclerodactylia			OFFSIDES
217	Scleroderma			OFFSIDES
218	Sebaceous hyperplasia			OFFSIDES
219	Sensation of warmth			SIDER
220	Shock			SIDER
221	Shunt occlusion			OFFSIDES
222	Skin Induration			OFFSIDES
223	Skin Wrinkling			OFFSIDES
224	Skin hypertrophy			OFFSIDES
225	Skin lesion			OFFSIDES
226	Skin necrosis			OFFSIDES
227	Skin tightness			OFFSIDES
228	Sleep Initiation and Maintenance Disorders		18397714	CTD
229	Somnolence			SIDER
230	Spinal column stenosis			OFFSIDES
231	Spondylitis			OFFSIDES
232	Stasis dermatitis			OFFSIDES
233	Stress			OFFSIDES
234	Subcutaneous nodule			OFFSIDES
235	Sudden Cardiac Death			OFFSIDES
236	Superior Vena Cava Syndrome			OFFSIDES
237	Suture rupture			OFFSIDES
238	Syncope			SIDER
239	Tachycardia			SIDER
240	Talipes			OFFSIDES
241	Thalamic Diseases		9763378	CTD
242	Therapeutic product ineffective			OFFSIDES
243	Throat irritation			SIDER
244	Tinnitus			SIDER
245	Transferrin saturation increased			OFFSIDES
246	Trembling			SIDER
247	Tremor			SIDER
248	Trigeminal palsy			OFFSIDES
249	Ulcer			OFFSIDES
250	Urticaria			SIDER
251	Vascular graft complication			OFFSIDES
252	Vascular stenosis			OFFSIDES
253	Vasculitic rash			OFFSIDES
254	Vasodilation procedure			SIDER
255	Vasodilation			SIDER
256	Venous Insufficiency			OFFSIDES
257	Venous stenosis			OFFSIDES
258	Visual Impairment			SIDER
259	Visual disturbance			SIDER
260	Walking aid user			OFFSIDES
261	Wheelchair user			OFFSIDES
262	Xerosis			OFFSIDES
263	effusion			OFFSIDES
264	nervous system disorder			SIDER
265	treatment failure			OFFSIDES

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