MetaADEDB 2.0 @ LMMD
Pyridostigmine Bromide
(RVOLLAQWKVFTGE-UHFFFAOYSA-N)
Structure
SMILES
C[n+]1cccc(c1)OC(=O)N(C)C
Type(s)
Approved; Investigational
ATC code(s)
N07AA02
Molecular Formula:
C9H13N2O2+
Molecular Weight:
181.212
Log P:
0.5715
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
0
TPSA:
33.42
CAS Number(s):
155-97-5
Synonym(s)
1.
Pyridostigmine Bromide
2.
Mestinon
3.
Pyridostigmine
4.
Bromide, Pyridostigmine
External Link(s)
MeSHD011729
PubChem Compound4991
BindingDB50367878
50313079
ChEBI8665
CHEMBLCHEMBL1115
DrugBankDB00545
DrugCentral2330
IUPHAR/BPS Guide to PHARMACOLOGY8994
KEGGcpd:C07410
Therapeutic Target DatabaseD0O2WB
ZINC2009
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 7OFFSIDES
US FAERS
2BradycardiaFAERS: 6OFFSIDES
SIDER
US FAERS
3AstheniaFAERS: 5OFFSIDES
SIDER
US FAERS
4Cardiac ArrestFAERS: 4SIDER
US FAERS
5Product substitution issueFAERS: 4OFFSIDES
US FAERS
6NauseaFAERS: 3SIDER
US FAERS
7Pharmaceutical product complaintFAERS: 3OFFSIDES
US FAERS
8Product quality issueFAERS: 3OFFSIDES
US FAERS
9Sinoatrial BlockFAERS: 3US FAERS
10VomitingFAERS: 3SIDER
US FAERS
11Abdominal PainFAERS: 2OFFSIDES
SIDER
US FAERS
12DroolingFAERS: 2US FAERS
13FatigueFAERS: 2OFFSIDES
US FAERS
14MalaiseFAERS: 2US FAERS
15Medication residue presentFAERS: 2US FAERS
16Myasthenia GravisFAERS: 2OFFSIDES
US FAERS
17Respiratory DepressionFAERS: 2US FAERS
18Toxicity to various agentsFAERS: 2US FAERS
19treatment failureFAERS: 2US FAERS
20Accidental exposure to productFAERS: 1US FAERS
21Accidental exposure to product by childFAERS: 1US FAERS
22Accidental overdoseFAERS: 1US FAERS
23Acute Coronary SyndromeFAERS: 1OFFSIDES
US FAERS
24AphasiaFAERS: 1US FAERS
25Blood magnesium decreasedFAERS: 1US FAERS
26Blood potassium decreasedFAERS: 1US FAERS
27Depressed Level of ConsciousnessFAERS: 1US FAERS
28Drug dose omissionFAERS: 1US FAERS
29Economic problemFAERS: 1US FAERS
30HypotensionFAERS: 1SIDER
US FAERS
31HypothyroidismFAERS: 1US FAERS
32HypoxiaFAERS: 1OFFSIDES
US FAERS
33Incorrect dose administeredFAERS: 1US FAERS
34Intentional self-injuryFAERS: 1US FAERS
35Large intestine perforationFAERS: 1US FAERS
36MalabsorptionFAERS: 1US FAERS
37Mental status changesFAERS: 1US FAERS
38Myasthenic SyndromeFAERS: 1OFFSIDES
US FAERS
39MyokymiaFAERS: 1US FAERS
40Neuromuscular toxicityFAERS: 1US FAERS
41ObesityFAERS: 1US FAERS
42Pancreatic carcinomaFAERS: 1US FAERS
43ParanoiaFAERS: 1US FAERS
44PoisoningFAERS: 1US FAERS
45Poor quality drug administeredFAERS: 1OFFSIDES
US FAERS
46Product physical issueFAERS: 1US FAERS
47Product storage errorFAERS: 1US FAERS
48SarcoidosisFAERS: 1US FAERS
49Suicide attemptFAERS: 1US FAERS
50TachycardiaFAERS: 1US FAERS
51Temperature regulation disorderFAERS: 1US FAERS
52Therapeutic response unexpected with drug substitutionFAERS: 1OFFSIDES
US FAERS
53Therapy non-responderFAERS: 1US FAERS
54Troponin increasedFAERS: 1US FAERS
55Urinary RetentionFAERS: 1US FAERS
56Visual ImpairmentFAERS: 1US FAERS
57Abdominal CrampsSIDER
58Abdominal bloatingSIDER
59AbscessOFFSIDES
60AcholiaOFFSIDES
61Acute bronchitisSIDER
62Acute myocardial infarctionOFFSIDES
63AdenitisOFFSIDES
64AdenocarcinomaOFFSIDES
65AgitationSIDER
66AlopeciaSIDER
67Altered visual depth perceptionOFFSIDES
68AlveolitisOFFSIDES
69AmblyopiaSIDER
70Amniotic fluid volumeOFFSIDES
71AngioedemaOFFSIDES
72AnosmiaOFFSIDES
73Anticholinergic SyndromeOFFSIDES
74AnxietyOFFSIDES
75Aortic valve sclerosisOFFSIDES
76Application site vesiclesOFFSIDES
77ArteriosclerosisOFFSIDES
78Aseptic MeningitisOFFSIDES
79AsthmaSIDER
80AthetosisOFFSIDES
81Atrial hypertrophyOFFSIDES
82Back disorderOFFSIDES
83Benign Prostatic HyperplasiaOFFSIDES
84Biliary dilatationOFFSIDES
85BlepharoptosisOFFSIDES
86BlepharospasmOFFSIDES
87Blood amylase increasedOFFSIDES
88Blood count abnormalOFFSIDES
89Blood iron abnormalOFFSIDES
90Blood parathyroid hormone increasedOFFSIDES
91Blood pressure fluctuationOFFSIDES
92Blood thyroid stimulating hormone abnormalOFFSIDES
93Blood triglycerides increasedOFFSIDES
94Bone painOFFSIDES
95Brain AbscessOFFSIDES
96Brain ConcussionOFFSIDES
97Breast CystOFFSIDES
98BronchiectasisOFFSIDES
99BronchitisSIDER
100Bulbar palsyOFFSIDES
101BursitisOFFSIDES
102CalciphylaxisOFFSIDES
103CellulitisOFFSIDES
104Cerebral ArteriosclerosisOFFSIDES
105Cervical myelopathyOFFSIDES
106Cervicobrachial syndromeOFFSIDES
107CheilitisOFFSIDES
108Chest discomfortSIDER
109Chest tightnessSIDER
110Chest wall painOFFSIDES
111Choking sensationOFFSIDES
112CholangiolitisOFFSIDES
113Cholinergic crisisSIDER
114Chronic respiratory failureOFFSIDES
115Chronic sinusitisOFFSIDES
116Circumstance or information capable of leading to medication errorOFFSIDES
117Cold sweatOFFSIDES
118Complications of maternal exposure to therapeutic drugsOFFSIDES
119Congenital anomaly of adrenal glandOFFSIDES
120Congenital tricuspid valve incompetenceOFFSIDES
121Contact DermatitisOFFSIDES
122CyanosisOFFSIDES
123DehydrationOFFSIDES
124Depressed moodSIDER
125DermatitisSIDER
126DiarrheaOFFSIDES
127Diffuse Large B-Cell LymphomaOFFSIDES
128DiplopiaOFFSIDES
129DiverticulosisOFFSIDES
130DrowsinessSIDER
131Drug exposure during pregnancyOFFSIDES
132Dry skinSIDER
133Duodenal UlcerOFFSIDES
134DuodenitisOFFSIDES
135DysphoniaOFFSIDES
136Dysthymic DisorderOFFSIDES
137Ejection Fraction DecreasedOFFSIDES
138Electrocardiogram ST-T changeOFFSIDES
139Endocarditis enterococcalOFFSIDES
140Endodontic procedureOFFSIDES
141Enterococcal infectionOFFSIDES
142EnterocolitisOFFSIDES
143EpistaxisOFFSIDES
SIDER
144Erectile dysfunctionOFFSIDES
145Esophageal PerforationOFFSIDES
146Essential TremorOFFSIDES
147Eye InfectionOFFSIDES
148Eye painSIDER
149Eyelid DiseasesOFFSIDES
150Feeling abnormalSIDER
151FlatulenceSIDER
152FolliculitisOFFSIDES
153Gastrointestinal PainSIDER
154Gastrointestinal sounds abnormalSIDER
155Gastrointestinal ulcerOFFSIDES
156GlossitisOFFSIDES
157Hallucinations, mixedOFFSIDES
158HeadacheSIDER
159HemiplegiaOFFSIDES
160Hepatitis AOFFSIDES
161Hepatitis B positiveOFFSIDES
162HyperreflexiaOFFSIDES
163HypersensitivitySIDER
164HypertransaminasaemiaOFFSIDES
165HyperventilationOFFSIDES
166HysterectomyOFFSIDES
167Increased bronchial secretionSIDER
168Joint stiffnessOFFSIDES
169LacrimationSIDER
170Left Ventricular HypertrophyOFFSIDES
171Left atrial dilatationOFFSIDES
172LethargySIDER
173LeukoaraiosisOFFSIDES
174LeukoplakiaOFFSIDES
175Lyme DiseaseOFFSIDES
176MacrocytosisOFFSIDES
177Mantle cell lymphomaOFFSIDES
178Mastication disorderOFFSIDES
179Muscle WeaknessOFFSIDES
180Muscular DystrophyOFFSIDES
181Musculoskeletal PainOFFSIDES
182Musculoskeletal discomfortSIDER
183Musculoskeletal stiffnessSIDER
184MyalgiaSIDER
185NasopharyngitisOFFSIDES
186Neck PainSIDER
187Nephrotic SyndromeOFFSIDES
188Nerve Root CompressionOFFSIDES
189Numbness of tongueSIDER
190OligohydramniosOFFSIDES
191Open woundOFFSIDES
192OphthalmoplegiaOFFSIDES
193OsteomyelitisOFFSIDES
194Pallor of skinSIDER
195PallorSIDER
196PancreatitisOFFSIDES
197Pelvic massOFFSIDES
198PertussisOFFSIDES
199PorokeratosisOFFSIDES
200Pulmonary pneumatoceleOFFSIDES
201QuadriparesisOFFSIDES
202Renal tubular atrophyOFFSIDES
203Respiratory FailureOFFSIDES
204Respiratory ParalysisSIDER
205Retroperitoneal fibrosisOFFSIDES
206RhonchiOFFSIDES
207Shoulder PainOFFSIDES
208SinusitisOFFSIDES
209Skin lacerationOFFSIDES
210Soft Tissue InfectionOFFSIDES
211Soft tissue necrosisOFFSIDES
212SomnolenceSIDER
213StiffnessSIDER
214Sudden Visual LossOFFSIDES
215SyndactylyOFFSIDES
216TalipesOFFSIDES
217Temperature intoleranceOFFSIDES
218ThrombophlebitisSIDER
219ThymomaOFFSIDES
220Tinea VersicolorOFFSIDES
221Tingling of extremitySIDER
222TracheobronchitisSIDER
223Tri-iodothyronine uptake decreasedOFFSIDES
224Tubal LigationOFFSIDES
225UlcerOFFSIDES
226Urinary IncontinenceSIDER
227UrticariaSIDER
228VIIth nerve paralysisOFFSIDES
229Ventricular hypokinesiaOFFSIDES
230VertebroplastyOFFSIDES
231VertigoSIDER
232Vitamin B 12 DeficiencyOFFSIDES
233effusionOFFSIDES
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