MetaADEDB 2.0 @ LMMD
Nitrous Oxide
(GQPLMRYTRLFLPF-UHFFFAOYSA-N)
Structure
SMILES
[N-]=[N+]=O
Type(s)
Approved; Vet_approved
ATC code(s)
N01AX13; N01AX63
Molecular Formula:
N2O
Molecular Weight:
44.013
Log P:
0.0637
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
0
TPSA:
54.46
CAS Number(s):
10024-97-2
Synonym(s)
1.
Nitrous Oxide
2.
Laughing Gas
3.
Nitrogen Protoxide
4.
Gas, Laughing
5.
Oxide, Nitrous
External Link(s)
MeSHD009609
PubChem Compound948
ChEBI17045
CHEMBLCHEMBL1234579
DrugBankDB06690
DrugCentral4238
KEGGcpd:C00887
dr:D00102
Therapeutic Target DatabaseD0O8DI
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug abuseFAERS: 40
Canada Vigilance: 1		Canada Vigilance
US FAERS
2Subacute combined cord degenerationFAERS: 25US FAERS
3AsphyxiaFAERS: 9US FAERS
4Blood homocysteine increasedFAERS: 7US FAERS
5AtaxiaFAERS: 6US FAERS
6Amino acid level increasedFAERS: 5US FAERS
7Toxicity to various agentsFAERS: 5US FAERS
8Euphoric moodFAERS: 4US FAERS
9HypoxiaFAERS: 415868998
19340552		CTD
OFFSIDES
US FAERS
10PolyneuropathyFAERS: 4US FAERS
11Acute polyneuropathyFAERS: 3US FAERS
12Cardiac ArrestFAERS: 3US FAERS
13DemyelinationFAERS: 3US FAERS
14Depressed Level of ConsciousnessFAERS: 3OFFSIDES
US FAERS
15Drug DependenceFAERS: 3US FAERS
16Intentional product misuseFAERS: 3US FAERS
17LeukopeniaFAERS: 3US FAERS
18Mood swingsFAERS: 3US FAERS
19Acute psychosisFAERS: 2US FAERS
20DizzinessFAERS: 215868998CTD
US FAERS
21Failure to ThriveFAERS: 2OFFSIDES
US FAERS
22HeadacheFAERS: 25354796CTD
US FAERS
23Impaired driving abilityFAERS: 2US FAERS
24Low birth weight babyFAERS: 2US FAERS
25MyelitisFAERS: 2US FAERS
26ParesisFAERS: 2US FAERS
27Personality ChangeFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
28SomnolenceFAERS: 2US FAERS
29Victim of sexual abuseFAERS: 2US FAERS
30VomitingFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
31Wheelchair userFAERS: 2US FAERS
32AgitationFAERS: 1US FAERS
33AllodyniaFAERS: 1US FAERS
34AmnesiaFAERS: 1US FAERS
35AnxietyFAERS: 1US FAERS
36AphasiaFAERS: 1US FAERS
37Bladder dysfunctionFAERS: 1US FAERS
38Blood folate decreasedFAERS: 1US FAERS
39Blood glucose fluctuationFAERS: 1US FAERS
40Burning sensationFAERS: 1US FAERS
41CardiomegalyFAERS: 1US FAERS
42Cerebral InfarctionFAERS: 1US FAERS
43Cerebral artery occlusionFAERS: 1US FAERS
44Cervical myelopathyFAERS: 1US FAERS
45ChokingFAERS: 1US FAERS
46CyanosisFAERS: 1US FAERS
47Deafness NeurosensoryFAERS: 1OFFSIDES
US FAERS
48Deep Vein ThrombosisFAERS: 1US FAERS
49DeliriumFAERS: 1US FAERS
50Depressed moodFAERS: 1US FAERS
51Device leakageFAERS: 1US FAERS
52Device use errorFAERS: 1US FAERS
53DisorientationFAERS: 1US FAERS
54EpistaxisFAERS: 1US FAERS
55Exposure via inhalationFAERS: 1US FAERS
56Feeling jitteryFAERS: 1US FAERS
57FrostbiteFAERS: 1US FAERS
58Gene MutationFAERS: 1US FAERS
59Guillain-Barre SyndromeFAERS: 1US FAERS
60HypersensitivityFAERS: 1US FAERS
61HypotensionFAERS: 1

View details

686426
1239221
4696443
6020977
 		CTD
US FAERS
62LaryngospasmFAERS: 1OFFSIDES
US FAERS
63MacrocytosisFAERS: 1US FAERS
64Maternal exposure during deliveryFAERS: 1US FAERS
65Memory impairmentFAERS: 1US FAERS
66Mental status changesFAERS: 1US FAERS
67MonoplegiaFAERS: 1US FAERS
68Neurological examination abnormalFAERS: 1OFFSIDES
US FAERS
69Neutrophil hypersegmented morphology presentFAERS: 1US FAERS
70OsteomyelitisFAERS: 1US FAERS
71PO2 decreasedFAERS: 1US FAERS
72PainFAERS: 1

View details

7969624
10568848
10910869
12033094
12477679
15892409
18458035
 		CTD
US FAERS
73PancytopeniaFAERS: 1US FAERS
74ParaparesisFAERS: 1US FAERS
75PetechiaeFAERS: 1US FAERS
76PneumoniaFAERS: 1US FAERS
77PneumothoraxFAERS: 1US FAERS
78Post stroke epilepsyFAERS: 1US FAERS
79Pulmonary EmbolismFAERS: 1US FAERS
80RadiculopathyFAERS: 1US FAERS
81RhabdomyolysisFAERS: 1OFFSIDES
US FAERS
82Romberg test positiveFAERS: 1US FAERS
83Seasonal Affective DisorderFAERS: 1US FAERS
84Subcutaneous EmphysemaFAERS: 1US FAERS
85Substance DependenceFAERS: 1US FAERS
86Sudden Cardiac DeathFAERS: 1US FAERS
87SyncopeFAERS: 1US FAERS
88Thermal burnFAERS: 1US FAERS
89ThrombocytopeniaFAERS: 1US FAERS
90TinnitusFAERS: 1US FAERS
91nervous system disorderFAERS: 1US FAERS
92Abdominal discomfortCanada Vigilance: 1Canada Vigilance
93AbuseOFFSIDES
94Accidental overdoseCanada Vigilance: 1Canada Vigilance
95AcidosisOFFSIDES
96AlkalosisOFFSIDES
97AlveolitisOFFSIDES
98AnisocoriaOFFSIDES
99Apnea2311153CTD
OFFSIDES
100Atrial tachycardiaOFFSIDES
101Atrioventricular BlockOFFSIDES
102Autoimmune thyroiditisOFFSIDES
103Bladder prolapseOFFSIDES
104Blood corticotrophin increasedOFFSIDES
105Blood potassium increasedOFFSIDES
106Body TemperatureOFFSIDES
107Bone erosionOFFSIDES
108Bone painOFFSIDES
109Bradycardia1239221
1867419		CTD
OFFSIDES
110Brain Diseases12574416CTD
111Brain Injuries10928976CTD
112Breast necrosisOFFSIDES
113Bulbar palsyOFFSIDES
114Bundle-Branch Block563196CTD
115Cardiomyopathies3414990CTD
116Cardiovascular insufficiencyOFFSIDES
117Catheter related complicationOFFSIDES
118Chest PainOFFSIDES
119ChromaturiaOFFSIDES
120Cocaine-Related Disorders16861150CTD
121ConfabulationOFFSIDES
122Conversion disorderOFFSIDES
123CystoceleOFFSIDES
124Dacryostenosis acquiredOFFSIDES
125Demyelinating Diseases9088497CTD
126Dental abscessOFFSIDES
127Dental cariesOFFSIDES
128Device FailureOFFSIDES
129Device malfunctionOFFSIDES
130Drug exposure during pregnancyOFFSIDES
131Drug ineffectiveCanada Vigilance: 1Canada Vigilance
132Drug toxicityOFFSIDES
133Dystonia15960645CTD
134Electrocardiogram ST segment abnormalOFFSIDES
135Electrocardiogram ST-T segment depressionOFFSIDES
136Emotional distressOFFSIDES
137Endotracheal intubation complicationOFFSIDES
138Enzyme abnormalityOFFSIDES
139Erythema MultiformeOFFSIDES
140ExcoriationOFFSIDES
141Food cravingOFFSIDES
142Gaze palsyOFFSIDES
143General physical health deteriorationOFFSIDES
144GlossoptosisOFFSIDES
145Head deformityOFFSIDES
146Heart Block10497454CTD
147Heart sounds abnormalOFFSIDES
148Heart valve stenosisOFFSIDES
149HemiparesisOFFSIDES
150HemiplegiaOFFSIDES
151HepatotoxicityOFFSIDES
152HidradenitisOFFSIDES
153HydronephrosisOFFSIDES
154Hyperalgesia10910869
16192778		CTD
155Hypercapnia4696443CTD
OFFSIDES
156Hyperemia8214724CTD
157Hypokinesia3713966CTD
158HypophagiaOFFSIDES
159HypospadiasOFFSIDES
160HysterectomyOFFSIDES
161Increased bronchial secretionOFFSIDES
162Infantile apnoeic attackOFFSIDES
163InfectionOFFSIDES
164Inhibitory drug interactionOFFSIDES
165Intestinal ObstructionOFFSIDES
166Intestinal infarctionOFFSIDES
167LacerationOFFSIDES
168Long QT SyndromeOFFSIDES
169Loose toothOFFSIDES
170Lymphocytic infiltrationOFFSIDES
171Mastication disorderOFFSIDES
172Mechanical ventilationOFFSIDES
173Memory Disorders12574416CTD
174Mental impairmentOFFSIDES
175Mental status changes postoperativeOFFSIDES
176Metabolic acidosisOFFSIDES
177Migraine with AuraOFFSIDES
178Movement Disorders3713967CTD
179Mucosal erosionOFFSIDES
180Muscle Rigidity2575721
4350546
5165426		CTD
181Muscle necrosisOFFSIDES
182Musculoskeletal PainOFFSIDES
183Nausea15868998CTD
184Nerve Degeneration18499598CTD
185NystagmusOFFSIDES
186Oculogyric crisisOFFSIDES
187OliguriaOFFSIDES
188Opioid-Related Disorders16192778CTD
189PCO2 decreasedOFFSIDES
190PallorOFFSIDES
191Peritoneal DialysisOFFSIDES
192PhlebitisOFFSIDES
193Post procedural complicationOFFSIDES
194Post procedural painOFFSIDES
195Postoperative Complications2311153CTD
196Postoperative Nausea and Vomiting10220941CTD
197Postoperative respiratory distressOFFSIDES
198Prenatal Exposure Delayed Effects3713966
3713967		CTD
199Procedural complicationOFFSIDES
200Procedural nauseaOFFSIDES
201Procedural vomitingOFFSIDES
202Product substitution issueCanada Vigilance: 1Canada Vigilance
203Psychotic symptomCanada Vigilance: 1Canada Vigilance
204Pulmonary congestionOFFSIDES
205Pustular psoriasisOFFSIDES
206RalesOFFSIDES
207RectoceleOFFSIDES
208Respiratory FailureOFFSIDES
209Respiratory Insufficiency2311153CTD
210Risus sardonicusOFFSIDES
211SacroiliitisOFFSIDES
212Seizures

View details

279595
3276852
6486511
9754883
9768802
 		CTD
213Skin neoplasm excisionOFFSIDES
214Somatoform DisorderOFFSIDES
215Sputum retentionOFFSIDES
216SubileusOFFSIDES
217Substance Withdrawal Syndrome572191
6517256
9754883		CTD
218Substance-Related Disorders9088497CTD
219TalipesOFFSIDES
220Tooth LossOFFSIDES
221Torsades de Pointes10402818CTD
222Trismus15096252CTD
223Troponin I increasedOFFSIDES
224Troponin increasedOFFSIDES
225Unresponsive to stimuliOFFSIDES
226Ventricular Fibrillation1239221CTD
OFFSIDES
227Ventricular hypokinesiaOFFSIDES
228Vitamin B 12 Deficiency6164371CTD
Powered by :

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120330

Copyright © 2019-2020 Laboratory of Molecular Modeling and Design, Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology. All rights reserved.