MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Beclomethasone

(NBMKJKDGKREAPL-DVTGEIKXSA-N)

Structure

SMILES: OCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)Cl
Molecular Formula:: C22H29ClO5
Molecular Weight:: 408.916
Log P:: 2.1650
Hydrogen Bond Acceptor:: 5
Hydrogen Bond Donor:: 3
TPSA:: 94.83
CAS Number(s):: 4419-39-0

Synonym(s)

Beclomethasone

Beclomethasone Dipropionate

AeroBec Forte

Aerobec

Aldecin

Apo-Beclomethasone

Ascocortonyl

Asmabec Clickhaler

Beclamet

10.

Beclazone

11.

Beclazone Easy Breathe

12.

Beclo AZU

13.

Beclo Asma

14.

Beclocort

15.

Becloforte

16.

Beclomet

17.

Beclometasone

18.

Beclorhinol

19.

Becloturmant

20.

Beclovent

21.

Becodisk

22.

Becodisks

23.

Beconase

24.

Beconase AQ

25.

Becotide

26.

Bemedrex Easyhaler

27.

Bronchocort

28.

Ecobec

29.

Filair

30.

Filair Forte

31.

Junik

32.

Nasobec Aqueous

33.

Prolair

34.

Propaderm

35.

Qvar

36.

Respocort

37.

Sanasthmax

38.

Sanasthmyl

39.

Vancenase

40.

Vanceril

41.

Ventolair

42.

Viarin

43.

Dipropionate, Beclomethasone

External Link(s)

MeSH	D001507
PubChem Compound	20469
BindingDB	53488
ChEBI	3001
CHEMBL	CHEMBL1586
IUPHAR/BPS Guide to PHARMACOLOGY	7059
KEGG	cpd:C06842 dr:D07495
ZINC	4097285

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Chest Pain	FAERS: 2		US FAERS
2	Maternal exposure during pregnancy	FAERS: 2		US FAERS
3	Angioedema	FAERS: 1		OFFSIDES SIDER US FAERS
4	Lymphadenopathy	FAERS: 1		US FAERS
5	Abdominal Pain			OFFSIDES
6	Abdominal discomfort			OFFSIDES
7	Abnormal vision			OFFSIDES
8	Abscess			OFFSIDES
9	Acid reflux			OFFSIDES
10	Acidosis			OFFSIDES
11	Acne			OFFSIDES
12	Actinic keratosis			OFFSIDES
13	Actinomycosis			OFFSIDES
14	Acute Coronary Syndrome			OFFSIDES
15	Acute glomerulonephritis			OFFSIDES
16	Acute myocardial infarction			OFFSIDES
17	Acute pulmonary histoplasmosis			OFFSIDES
18	Adenoidal disorder			OFFSIDES
19	Adjustment disorder with depressed mood			OFFSIDES
20	Adrenal insufficiency neonatal			OFFSIDES
21	Ageusia			OFFSIDES SIDER
22	Agitation			SIDER
23	Agoraphobia			OFFSIDES
24	Airway Obstruction		View details 11568990 15144908 15841673 18430318	CTD
25	Allergy to arthropod bite			OFFSIDES
26	Alopecia			OFFSIDES
27	Alveoloplasty			OFFSIDES
28	Amniotic cavity disorder			OFFSIDES
29	Amyloidosis			OFFSIDES
30	Anaphylactic shock			SIDER
31	Anhedonia			OFFSIDES
32	Ankylosing spondylitis			OFFSIDES
33	Anosmia			OFFSIDES
34	Antiphospholipid Syndrome			OFFSIDES
35	Anuria			OFFSIDES
36	Aortic bypass			OFFSIDES
37	Apathy			OFFSIDES
38	Aphonia			OFFSIDES
39	Application site burn			OFFSIDES
40	Arterial Injury			OFFSIDES
41	Arthritis			OFFSIDES
42	Asterixis			OFFSIDES
43	Asthma		View details 81404 1443864 2844548 6958474 7148765 7312482 7437783 7540862 8111605 8534483 8694041 8762487 8874658 9203805 9385125 9657561 9700034 10075616 10322818 10347961 10513351 10588598 10639760 10764315 10813552 10983617 11379808 11379810 11393418 11422148 11449530 11527250 11555383 11559968 11758890 11980116 12114351 12153692 12166584 12360108 12449158 12449667 12464949 12489251 12587966 15025036 16270722 16509916 16973987 17564282 17872493 18430318 21762500 22221427 22357130 23512537	CTD OFFSIDES SIDER
44	Atrioventricular Block			OFFSIDES
45	Back Pain			SIDER
46	Bacteria sputum identified			OFFSIDES
47	Bacterial disease carrier			OFFSIDES
48	Bacterial sepsis			OFFSIDES
49	Benign neoplasm of thyroid gland			OFFSIDES
50	Biopsy bone abnormal			OFFSIDES
51	Bipolar Disorder		2750983	CTD
52	Blood corticotrophin			OFFSIDES
53	Blood cortisol abnormal			OFFSIDES
54	Blood cortisol decreased			OFFSIDES
55	Blood cortisol increased			OFFSIDES
56	Blood electrolytes increased			OFFSIDES
57	Blood folate increased			OFFSIDES
58	Blood gases abnormal			OFFSIDES
59	Blood thyroid stimulating hormone			OFFSIDES
60	Bone Demineralization, Pathologic		9232087	CTD
61	Bone Resorption		2028429	CTD
62	Bone density decreased			OFFSIDES
63	Bone erosion			OFFSIDES
64	Bone fragmentation			OFFSIDES
65	Bone lesion			OFFSIDES
66	Brain Concussion			OFFSIDES
67	Breast cancer stage III			OFFSIDES
68	Bronchial Hyperreactivity		17336541 18391481 18577381	CTD
69	Bronchial irritation			OFFSIDES
70	Bronchiectasis			OFFSIDES
71	Bronchiolitis			OFFSIDES
72	Bronchitis, Chronic		1489129	CTD
73	Bronchitis			OFFSIDES
74	Bronchopneumonia			OFFSIDES
75	Bronchospasm			SIDER
76	Bulbar palsy			OFFSIDES
77	Bunion			OFFSIDES
78	Candidiasis		2844548	CTD
79	Cardiac monitoring			OFFSIDES
80	Cardioactive drug level below therapeutic			OFFSIDES
81	Cardiovascular insufficiency			OFFSIDES
82	Cataract			OFFSIDES SIDER
83	Catheter placement			OFFSIDES
84	Cellulitis			OFFSIDES
85	Cerebellar Ataxia			OFFSIDES
86	Cerebral Arteriosclerosis			OFFSIDES
87	Choking sensation			OFFSIDES
88	Cholangiolitis			OFFSIDES
89	Chronic Obstructive Airway Disease			OFFSIDES
90	Chronic left ventricular failure			OFFSIDES
91	Chronic sinusitis			OFFSIDES
92	Circumstance or information capable of leading to medication error			OFFSIDES
93	Clostridium difficile colitis			OFFSIDES
94	Cluster Headache			OFFSIDES
95	Coagulation factor VIII level decreased			OFFSIDES
96	Complications of maternal exposure to therapeutic drugs			OFFSIDES
97	Congenital Hydrocephalus			OFFSIDES
98	Congenital absence of cranial vault			OFFSIDES
99	Congenital cystic kidney disease			OFFSIDES
100	Congenital heart valve disorder			OFFSIDES
101	Congenital osteodystrophy			OFFSIDES
102	Contracture			OFFSIDES
103	Cor pulmonale			OFFSIDES
104	Cubital Tunnel Syndrome			OFFSIDES
105	Cyanosis			OFFSIDES
106	Cystic Fibrosis			OFFSIDES
107	Dental Fistula			OFFSIDES
108	Depressed mood			OFFSIDES
109	Dermatitis			SIDER
110	Diaphragmatic Hernia			OFFSIDES
111	Diarrhea			OFFSIDES
112	Diplopia			OFFSIDES
113	Diverticulum			OFFSIDES
114	Dizziness			SIDER
115	Double ureter			OFFSIDES
116	Drug exposure during pregnancy			OFFSIDES
117	Dry skin			OFFSIDES
118	Dysphonia		6648863 7351447 7664859	CTD OFFSIDES SIDER
119	Dyspnea		2844548 22069361	CTD
120	Dyspnoea exacerbated			OFFSIDES
121	Dysuria			OFFSIDES
122	Ear congestion			OFFSIDES
123	Ear discomfort			OFFSIDES
124	Eczema			OFFSIDES
125	Electrocardiogram ST-T change			OFFSIDES
126	Emotional distress			OFFSIDES
127	End-tidal CO2 decreased			OFFSIDES
128	Endodontic procedure			OFFSIDES
129	Endometrial sarcoma			OFFSIDES
130	Enthesopathy			OFFSIDES
131	Eosinophil percentage increased			OFFSIDES
132	Eosinophilia		View details 1527319 8535097 10351924 12944497	CTD
133	Eosinophilic Pneumonia			OFFSIDES
134	Epistaxis			OFFSIDES SIDER
135	Erysipelas			OFFSIDES
136	Erythema Nodosum			OFFSIDES
137	Erythema	Canada Vigilance: 1		Canada Vigilance
138	Escherichia infection			OFFSIDES
139	Escherichia sepsis			OFFSIDES
140	Esophageal Stenosis			OFFSIDES
141	Essential Hypertension		8567040	CTD
142	Exposure to contaminated device			OFFSIDES
143	Eye Infection			OFFSIDES
144	Factor II deficiency			OFFSIDES
145	Factor V deficiency			OFFSIDES
146	Factor VII Deficiency			OFFSIDES
147	Fasciitis			OFFSIDES
148	Fasciotomy			OFFSIDES
149	Floppy iris syndrome			OFFSIDES
150	Fluid overload			OFFSIDES
151	Gambling			OFFSIDES
152	Gamma-Glutamyltransferase Increased			OFFSIDES
153	Gastrointestinal ulcer perforation			OFFSIDES
154	Gingival graft			OFFSIDES
155	Glaucoma			SIDER
156	Granuloma			OFFSIDES
157	Growth Disorders		9385125 16509916	CTD
158	Growth retardation			SIDER
159	Headache		10400480	CTD SIDER
160	Helicobacter pylori identification test positive			OFFSIDES
161	Hemisensory Neglect			OFFSIDES
162	Hepatosplenic candidiasis			OFFSIDES
163	Hip surgery			OFFSIDES
164	Histamine level increased			OFFSIDES
165	Histoplasmosis			OFFSIDES
166	Hoarseness		3475563	CTD OFFSIDES
167	Hypercapnia			OFFSIDES
168	Hypercapnic encephalopathy			OFFSIDES
169	Hyperkeratosis			OFFSIDES
170	Hyperpigmentation			OFFSIDES
171	Hypersensitivity			SIDER
172	Hypertrichosis			OFFSIDES SIDER
173	Hyperventilation			OFFSIDES
174	Hypervigilance			OFFSIDES
175	Hypokinesia			OFFSIDES
176	Hypophagia			OFFSIDES
177	Hypospadias			OFFSIDES
178	Hypoxia			OFFSIDES
179	Incontinence			OFFSIDES
180	Incorrect route of drug administration			OFFSIDES
181	Increased upper airway secretion			OFFSIDES
182	Induration			OFFSIDES
183	Infant, Premature, Diseases		11015126	CTD
184	Infection			OFFSIDES SIDER
185	Inflammation		12166584 29986831	CTD
186	Infusion site bruising			OFFSIDES
187	Infusion site mobility decreased			OFFSIDES
188	Infusion site pain			OFFSIDES
189	Infusion site rash			OFFSIDES
190	Injection site calcification			OFFSIDES
191	Injection site dermatitis			OFFSIDES
192	Injection site macule			OFFSIDES
193	Injection site urticaria			OFFSIDES
194	Intercostal neuralgia			OFFSIDES
195	Intervertebral Disc Degeneration			OFFSIDES
196	Intestinal Diseases		23516624	CTD
197	Joint Range of Motion Decreased			OFFSIDES
198	Laryngeal erythema			OFFSIDES
199	Left atrial dilatation			OFFSIDES
200	Lichen Planus			OFFSIDES
201	Life expectancy shortened			OFFSIDES
202	Ligament rupture			OFFSIDES
203	Lightheadedness			SIDER
204	Lip exfoliation			OFFSIDES
205	Lipodystrophy acquired			OFFSIDES
206	Live Birth			OFFSIDES
207	Livedo Reticularis			OFFSIDES
208	Local reaction			OFFSIDES
209	Loose tooth			OFFSIDES
210	Lung Diseases, Obstructive		9232087 16594601	CTD
211	Lung diseases		12944497	CTD
212	Lung infection pseudomonal			OFFSIDES
213	Lymphocyte count decreased			OFFSIDES
214	Lymphocyte percentage decreased			OFFSIDES
215	Malignant tumour excision			OFFSIDES
216	Mastoiditis	Canada Vigilance: 1		Canada Vigilance
217	Medication residue			OFFSIDES
218	Meniscus removal			OFFSIDES
219	Mesothelioma			OFFSIDES
220	Metastases to thorax			OFFSIDES
221	Multiple Myeloma			OFFSIDES
222	Musculoskeletal Pain			OFFSIDES
223	Mycotic allergy			OFFSIDES
224	Myeloma recurrence			OFFSIDES
225	Nasal discomfort			OFFSIDES SIDER
226	Nasopharyngitis			OFFSIDES SIDER
227	Nausea			SIDER
228	Neonatal anuria			OFFSIDES
229	Neonatal hypotension			OFFSIDES
230	Neoplasm Metastasis		22374800	CTD
231	Nephrogenic Diabetes Insipidus			OFFSIDES
232	Nephrotic Syndrome			OFFSIDES
233	Neutropenic sepsis			OFFSIDES
234	Neutrophil Chemotactic Response, Abnormal		22374800	CTD
235	Nodule on extremity			OFFSIDES
236	Nodule			OFFSIDES
237	Nystagmus			OFFSIDES
238	Ocular Hypertension		7862403	CTD
239	Olfaction Disorders		1932926 8560170	CTD
240	Open reduction of fracture			OFFSIDES
241	Optic Disc Edema			OFFSIDES
242	Oral Cavity Fistula			OFFSIDES
243	Oral mucosa atrophy			OFFSIDES
244	Oral mucosal exfoliation			OFFSIDES
245	Oropharyngeal candidiasis			OFFSIDES SIDER
246	Oropharyngeal pain			OFFSIDES
247	Orthopnea			OFFSIDES
248	Osteoporosis			OFFSIDES
249	Pain			OFFSIDES SIDER
250	Peripheral occlusive disease			OFFSIDES
251	Pharmaceutical product complaint			OFFSIDES
252	Pharyngitis			SIDER
253	Pharyngolaryngeal Pain			OFFSIDES
254	Plasmacytosis			OFFSIDES
255	Plasmapheresis			OFFSIDES
256	Pleuropericarditis			OFFSIDES
257	Pneumatosis Cystoides Intestinalis			OFFSIDES
258	Pneumobilia			OFFSIDES
259	Pneumoconiosis			OFFSIDES
260	Polymenorrhea			OFFSIDES
261	Polyomavirus-associated nephropathy			OFFSIDES
262	Polyuria			OFFSIDES
263	Poor quality sleep			OFFSIDES
264	Postmenopausal bleeding			OFFSIDES
265	Postoperative Complications		15925911	CTD
266	Pre-Eclampsia			OFFSIDES
267	Primary sequestrum			OFFSIDES
268	Procedural hypertension			OFFSIDES
269	Productive Cough			OFFSIDES
270	Pulmonary Edema		17336541	CTD
271	Pulmonary Eosinophilia		10850854	CTD
272	Pulmonary congestion			OFFSIDES
273	Purulent discharge			OFFSIDES
274	Pyogenic granuloma			OFFSIDES
275	Radiotherapy to brain			OFFSIDES
276	Recall phenomenon			OFFSIDES
277	Red blood cell schistocytes present			OFFSIDES
278	Renal cyst			OFFSIDES
279	Renal tubular necrosis			OFFSIDES
280	Respiratory Failure			OFFSIDES
281	Respiratory Hypersensitivity		1527319	CTD
282	Rhinalgia			OFFSIDES
283	Rhinitis perennial			SIDER
284	Rhinitis, Allergic, Perennial		2861220 18422164 19233485	CTD
285	Rhinitis		7116616 10351924	CTD OFFSIDES SIDER
286	Rhinorrhea			OFFSIDES
287	Rosacea		10192164	CTD
288	Rubella			OFFSIDES
289	Sacroiliitis			OFFSIDES
290	Seizures		7148765	CTD
291	Sequestrectomy			OFFSIDES
292	Single functional kidney			OFFSIDES
293	Sinus headache			OFFSIDES
294	Sinusitis		7327846 8560170	CTD OFFSIDES SIDER
295	Skin hypertrophy			OFFSIDES
296	Skin lesion			OFFSIDES
297	Skin neoplasm excision			OFFSIDES
298	Small intestine carcinoma			OFFSIDES
299	Sneezing			SIDER
300	Snoring			OFFSIDES
301	Soft Tissue Injuries			OFFSIDES
302	Status Asthmaticus		114264	CTD
303	Stem cell transplant			OFFSIDES
304	Steroid withdrawal syndrome			OFFSIDES
305	Stress			OFFSIDES
306	Sudden death			OFFSIDES
307	Synovitis			OFFSIDES
308	T-Cell Lymphoma			OFFSIDES
309	Talipes			OFFSIDES
310	Tendinitis			OFFSIDES
311	Testicular mass			OFFSIDES
312	Tinea			OFFSIDES
313	Tooth Extraction			OFFSIDES
314	Tooth Infection			OFFSIDES
315	Tooth Loss			OFFSIDES
316	Troponin increased			OFFSIDES
317	Ulcer			SIDER
318	Urinary Tract Pain			OFFSIDES
319	Urinary bladder polyp			OFFSIDES
320	Urine flow decreased			OFFSIDES
321	Urticaria			SIDER
322	Uterine Perforation			OFFSIDES
323	VIIth nerve paralysis			OFFSIDES
324	Vascular anomaly			OFFSIDES
325	Vascular insufficiency			OFFSIDES
326	Venous Injury			OFFSIDES
327	Ventricular Fibrillation			OFFSIDES
328	Vitrectomy			OFFSIDES
329	Vulvovaginal dryness			OFFSIDES
330	Wheezing			SIDER
331	Wound Complication			OFFSIDES
332	Wound decomposition			OFFSIDES
333	Wound dehiscence			OFFSIDES
334	fibroma			OFFSIDES

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