MetaADEDB 2.0 @ LMMD
Amitriptyline
(KRMDCWKBEZIMAB-UHFFFAOYSA-N)
Structure
SMILES
CN(CCC=C1c2ccccc2CCc2c1cccc2)C
Type(s)
Approved
ATC code(s)
N06AA09; N06CA01
Molecular Formula:
C20H23N
Molecular Weight:
277.403
Log P:
4.1686
Hydrogen Bond Acceptor:
1
Hydrogen Bond Donor:
0
TPSA:
3.24
CAS Number(s):
50-48-6; 549-18-8
Synonym(s)
1.
Amitriptyline
2.
Amineurin
3.
Amitrip
4.
Amitriptylin Beta
5.
Amitriptylin Desitin
6.
Amitriptylin RPh
7.
Amitriptylin-Neuraxpharm
8.
Amitriptyline Hydrochloride
9.
Amitrol
10.
Anapsique
11.
Apo-Amitriptyline
12.
Damilen
13.
Domical
14.
Elavil
15.
Endep
16.
Laroxyl
17.
Lentizol
18.
Novoprotect
19.
Saroten
20.
Sarotex
21.
Syneudon
22.
Triptafen
23.
Tryptanol
24.
Tryptine
25.
Tryptizol
26.
Amitriptylin Neuraxpharm
27.
Apo Amitriptyline
28.
Desitin, Amitriptylin
29.
RPh, Amitriptylin
External Link(s)
MeSHD000639
PubChem Compound2160
BindingDB50020712
ChEBI2666
CHEMBLCHEMBL629
DrugBankDB00321
DrugCentral180
IUPHAR/BPS Guide to PHARMACOLOGY200
KEGGcpd:C06824
dr:D07448
Therapeutic Target DatabaseD0Y5UG
ZINC968257
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Toxicity to various agentsFAERS: 74
Canada Vigilance: 1
Canada Vigilance
US FAERS
2OverdoseFAERS: 53
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
3HypotensionFAERS: 30
Canada Vigilance: 7

View details

CTD
SIDER
Canada Vigilance
US FAERS
4Suicide attemptFAERS: 30
Canada Vigilance: 1
Canada Vigilance
US FAERS
5Completed SuicideFAERS: 29
Canada Vigilance: 23
Canada Vigilance
US FAERS
6Drug ineffectiveFAERS: 27
Canada Vigilance: 6
Canada Vigilance
OFFSIDES
US FAERS
7SomnolenceFAERS: 22
Canada Vigilance: 16
Canada Vigilance
SIDER
US FAERS
8TachycardiaFAERS: 22
Canada Vigilance: 10
6173521
9803478
16040888
CTD
SIDER
Canada Vigilance
US FAERS
9DizzinessFAERS: 17
Canada Vigilance: 19

View details

CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
10AgitationFAERS: 15
Canada Vigilance: 12
Canada Vigilance
SIDER
US FAERS
11NauseaFAERS: 15
Canada Vigilance: 9
Canada Vigilance
OFFSIDES
SIDER
US FAERS
12Respiratory DepressionFAERS: 15US FAERS
13Sinus TachycardiaFAERS: 13US FAERS
14Drug abuseFAERS: 12US FAERS
15HeadacheFAERS: 12
Canada Vigilance: 5
4169996
6401849
19080105
CTD
SIDER
Canada Vigilance
US FAERS
16MalaiseFAERS: 12SIDER
US FAERS
17DysarthriaFAERS: 11
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
18Feeling abnormalFAERS: 11
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
19MydriasisFAERS: 11
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
20PalpitationsFAERS: 11
Canada Vigilance: 4
Canada Vigilance
SIDER
US FAERS
21AnxietyFAERS: 10
Canada Vigilance: 7
Canada Vigilance
OFFSIDES
SIDER
US FAERS
22AstheniaFAERS: 10
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
SIDER
US FAERS
23Cardiac ArrestFAERS: 10US FAERS
24Mental status changesFAERS: 9SIDER
US FAERS
25PainFAERS: 9
Canada Vigilance: 1

View details

CTD
OFFSIDES
Canada Vigilance
US FAERS
26Respiratory FailureFAERS: 9OFFSIDES
US FAERS
27DisorientationFAERS: 8
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
28FatigueFAERS: 8
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
SIDER
US FAERS
29VomitingFAERS: 8
Canada Vigilance: 7
Canada Vigilance
SIDER
US FAERS
30ConstipationFAERS: 7
Canada Vigilance: 7
2858187CTD
SIDER
Canada Vigilance
US FAERS
31Depressed Level of ConsciousnessFAERS: 7
Canada Vigilance: 1
Canada Vigilance
US FAERS
32SyncopeFAERS: 7
Canada Vigilance: 3
11144697CTD
SIDER
Canada Vigilance
US FAERS
33TremorFAERS: 7
Canada Vigilance: 8

View details

CTD
SIDER
Canada Vigilance
US FAERS
34Drug dispensing errorFAERS: 6OFFSIDES
US FAERS
35HypersensitivityFAERS: 6
Canada Vigilance: 2
Canada Vigilance
US FAERS
36Medication ErrorFAERS: 6
Canada Vigilance: 3
Canada Vigilance
US FAERS
37Metabolic acidosisFAERS: 6US FAERS
38Renal painFAERS: 6US FAERS
39Ventricular FibrillationFAERS: 6SIDER
US FAERS
40Ventricular arrhythmiaFAERS: 6US FAERS
41Acute kidney injuryFAERS: 5
Canada Vigilance: 1
6842224CTD
Canada Vigilance
US FAERS
42Chest PainFAERS: 5
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
43Drug ineffective for unapproved indicationFAERS: 5US FAERS
44GlaucomaFAERS: 5
Canada Vigilance: 2
Canada Vigilance
US FAERS
45NervousnessFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
46Product substitution issueFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
47Status EpilepticusFAERS: 57001962CTD
US FAERS
48TinnitusFAERS: 5
Canada Vigilance: 2
18308819CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
49Abdominal Compartment SyndromeFAERS: 4US FAERS
50Atrioventricular BlockFAERS: 4882168
3963932
11089775
CTD
SIDER
US FAERS
51Burning sensationFAERS: 4OFFSIDES
US FAERS
52Drug withdrawal syndromeFAERS: 4SIDER
US FAERS
53Electrocardiogram abnormalFAERS: 4US FAERS
54EncephalitisFAERS: 4OFFSIDES
US FAERS
55HypomaniaFAERS: 4SIDER
US FAERS
56Initial insomniaFAERS: 4US FAERS
57Intestinal ObstructionFAERS: 4US FAERS
58LethargyFAERS: 4OFFSIDES
US FAERS
59Myocardial InfarctionFAERS: 4SIDER
US FAERS
60Product use in unapproved indicationFAERS: 4US FAERS
61RestlessnessFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
62StrabismusFAERS: 4US FAERS
63Unresponsive to stimuliFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
64Urinary RetentionFAERS: 4
Canada Vigilance: 4
4668901CTD
SIDER
Canada Vigilance
US FAERS
65Accidental exposure to product by childFAERS: 3US FAERS
66AlopeciaFAERS: 3
Canada Vigilance: 6
Canada Vigilance
SIDER
US FAERS
67AmnesiaFAERS: 3
Canada Vigilance: 4
7229637CTD
OFFSIDES
Canada Vigilance
US FAERS
68AngerFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
69Anticholinergic SyndromeFAERS: 3OFFSIDES
US FAERS
70Chest discomfortFAERS: 3US FAERS
71Coma scale abnormalFAERS: 3US FAERS
72CyanosisFAERS: 3US FAERS
73DeliriumFAERS: 3
Canada Vigilance: 1

View details

CTD
Canada Vigilance
US FAERS
74Depressed moodFAERS: 3OFFSIDES
US FAERS
75Diabetic KetoacidosisFAERS: 3US FAERS
76DyspepsiaFAERS: 3
Canada Vigilance: 1
15943846CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
77EpilepsyFAERS: 35823053CTD
US FAERS
78Exposure during breast feedingFAERS: 3US FAERS
79HypersomniaFAERS: 3US FAERS
80HyperthyroidismFAERS: 3US FAERS
81Incorrect dose administeredFAERS: 3OFFSIDES
US FAERS
82Intentional self-injuryFAERS: 3OFFSIDES
US FAERS
83Long QT SyndromeFAERS: 3

View details

CTD
US FAERS
84NephrolithiasisFAERS: 3US FAERS
85Nerve injuryFAERS: 3US FAERS
86Oropharyngeal painFAERS: 3
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
US FAERS
87Prescription drug used without a prescriptionFAERS: 3US FAERS
88PruritusFAERS: 3
Canada Vigilance: 5
3335290
6057380
15106034
CTD
SIDER
Canada Vigilance
US FAERS
89Retrograde amnesiaFAERS: 3US FAERS
90Sleep ParalysisFAERS: 3US FAERS
91Therapeutic response unexpectedFAERS: 3US FAERS
92ThirstFAERS: 3US FAERS
93ThrombophlebitisFAERS: 3US FAERS
94Visual ImpairmentFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
95Accidental exposure to productFAERS: 2US FAERS
96Activities of daily living impairedFAERS: 2OFFSIDES
US FAERS
97Altered state of consciousnessFAERS: 2US FAERS
98Anaphylactic shockFAERS: 2US FAERS
99AphasiaFAERS: 2US FAERS
100AtaxiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
101Back PainFAERS: 27497563CTD
US FAERS
102Blood glucose increasedFAERS: 2US FAERS
103BradycardiaFAERS: 2
Canada Vigilance: 1

View details

CTD
Canada Vigilance
US FAERS
104Brain stem syndromeFAERS: 2US FAERS
105Cerebrovascular accidentFAERS: 2SIDER
US FAERS
106ChillsFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
107ChromaturiaFAERS: 2US FAERS
108Conversion disorderFAERS: 2US FAERS
109CryingFAERS: 2
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
110Drug administration errorFAERS: 2US FAERS
111Drug exposure during pregnancyFAERS: 2US FAERS
112Drug toxicityFAERS: 2US FAERS
113Electrocardiogram PQ interval prolongedFAERS: 2US FAERS
114Emotional povertyFAERS: 2US FAERS
115EpistaxisFAERS: 2OFFSIDES
US FAERS
116ErythemaFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
117FlushingFAERS: 2
Canada Vigilance: 2
Canada Vigilance
US FAERS
118Gastrointestinal PainFAERS: 2US FAERS
119IncoherentFAERS: 2US FAERS
120Loss of bladder sensationFAERS: 2US FAERS
121Migraine with AuraFAERS: 2US FAERS
122Musculoskeletal PainFAERS: 2OFFSIDES
US FAERS
123Night sweatsFAERS: 2US FAERS
124ParanoiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
125Pharmaceutical product complaintFAERS: 2US FAERS
126PneumoniaFAERS: 2US FAERS
127PoisoningFAERS: 2882168
17359955
CTD
US FAERS
128Poor feeding infantFAERS: 2US FAERS
129Pupillary light reflex tests abnormalFAERS: 2US FAERS
130Respiratory arrestFAERS: 2US FAERS
131Restless Legs SyndromeFAERS: 2US FAERS
132RhabdomyolysisFAERS: 26842224CTD
US FAERS
133Serotonin SyndromeFAERS: 28869767
9031998
CTD
SIDER
US FAERS
134ShockFAERS: 2SIDER
US FAERS
135Sinus bradycardiaFAERS: 2US FAERS
136SinusitisFAERS: 2OFFSIDES
US FAERS
137SyndactylyFAERS: 2US FAERS
138TrismusFAERS: 2US FAERS
139Troponin I increasedFAERS: 2US FAERS
140UrticariaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
141Weight decreasedFAERS: 2US FAERS
142Wrong drug administeredFAERS: 2US FAERS
143nervous system disorderFAERS: 2US FAERS
144AbasiaFAERS: 1US FAERS
145Accidental drug intake by childFAERS: 1US FAERS
146Acute Lung InjuryFAERS: 1US FAERS
147Adverse eventFAERS: 1OFFSIDES
US FAERS
148Alcohol interactionFAERS: 1US FAERS
149AnhedoniaFAERS: 1OFFSIDES
US FAERS
150AnhidrosisFAERS: 1US FAERS
151Anion gap abnormalFAERS: 1US FAERS
152AnorexiaFAERS: 1OFFSIDES
SIDER
US FAERS
153AnorgasmiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
154Aorticopulmonary Septal DefectFAERS: 1US FAERS
155ApathyFAERS: 1OFFSIDES
US FAERS
156AphagiaFAERS: 1US FAERS
157AphoniaFAERS: 1US FAERS
158ArthralgiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
159AsthmaFAERS: 1OFFSIDES
US FAERS
160AuraFAERS: 1OFFSIDES
US FAERS
161Blood antidiuretic hormone increasedFAERS: 1US FAERS
162Blood creatine phosphokinase MB increasedFAERS: 1US FAERS
163Blood creatine phosphokinase increasedFAERS: 1US FAERS
164Blood immunoglobulin M abnormalFAERS: 1US FAERS
165Blood pH decreasedFAERS: 1US FAERS
166Breathing-related sleep disorderFAERS: 1US FAERS
167Bronchial HyperreactivityFAERS: 1US FAERS
168BronchitisFAERS: 1US FAERS
169BronchopneumoniaFAERS: 1US FAERS
170BruxismFAERS: 1OFFSIDES
US FAERS
171Butterfly rashFAERS: 1US FAERS
172CardiotoxicityFAERS: 1US FAERS
173Cerebral atrophyFAERS: 1US FAERS
174ChoreaFAERS: 13949727CTD
US FAERS
175Critical illness myopathyFAERS: 1US FAERS
176DehydrationFAERS: 1OFFSIDES
US FAERS
177Diabetes InsipidusFAERS: 1US FAERS
178DiplopiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
179DroolingFAERS: 1US FAERS
180Drug DependenceFAERS: 1US FAERS
181Drug abuserFAERS: 1US FAERS
182Drug dose titration not performedFAERS: 1US FAERS
183Drug level changedFAERS: 1US FAERS
184Drug level increasedFAERS: 1
Canada Vigilance: 5
Canada Vigilance
US FAERS
185Drug prescribing errorFAERS: 1OFFSIDES
US FAERS
186Drug screen positiveFAERS: 1OFFSIDES
US FAERS
187Dry skinFAERS: 1US FAERS
188DysuriaFAERS: 1OFFSIDES
US FAERS
189Economic problemFAERS: 1US FAERS
190Electrocardiogram ST segment abnormalFAERS: 1US FAERS
191Electrocardiogram changeFAERS: 1US FAERS
192Emotional disorderFAERS: 1US FAERS
193Erectile dysfunctionFAERS: 1SIDER
US FAERS
194EructationFAERS: 1US FAERS
195Euphoric moodFAERS: 1US FAERS
196False positive investigation resultFAERS: 1US FAERS
197Feeling jitteryFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
198Feeling of body temperature changeFAERS: 1US FAERS
199FlatulenceFAERS: 1US FAERS
200Food cravingFAERS: 1US FAERS
201FrustrationFAERS: 1US FAERS
202Gastrointestinal obstructionFAERS: 1US FAERS
203Gene MutationFAERS: 1US FAERS
204Grip strength decreasedFAERS: 1US FAERS
205Hallucinations, mixedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
206Head discomfortFAERS: 1US FAERS
207HepatotoxicityFAERS: 1US FAERS
208HostilityFAERS: 1US FAERS
209HypokinesiaFAERS: 1US FAERS
210HypophagiaFAERS: 1US FAERS
211HypoventilationFAERS: 1US FAERS
212IleusFAERS: 1US FAERS
213Impaired driving abilityFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
214Impaired gastric emptyingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
215InfarctionFAERS: 1US FAERS
216Intercepted drug dispensing errorFAERS: 1US FAERS
217Intercepted drug prescribing errorFAERS: 1US FAERS
218Limb discomfortFAERS: 1OFFSIDES
US FAERS
219Lip swellingFAERS: 1US FAERS
220Lower respiratory tract infectionFAERS: 1US FAERS
221MastitisFAERS: 1US FAERS
222Maternal exposure during pregnancyFAERS: 1US FAERS
223Mechanical ileusFAERS: 1US FAERS
224MegacolonFAERS: 1US FAERS
225Memory impairmentFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
226Metabolic alkalosisFAERS: 1US FAERS
227Mood swingsFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
228Musculoskeletal stiffnessFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
229MyalgiaFAERS: 1US FAERS
230Myasthenia GravisFAERS: 1US FAERS
231MyocarditisFAERS: 112638679
16040888
CTD
US FAERS
232NarcolepsyFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
233Neonatal disorderFAERS: 1US FAERS
234Neuroleptic Malignant SyndromeFAERS: 1SIDER
US FAERS
235Nipple painFAERS: 1US FAERS
236No adverse eventFAERS: 1US FAERS
237Obsessive-Compulsive DisorderFAERS: 1US FAERS
238Oral administration complicationFAERS: 1US FAERS
239PallorFAERS: 1
Canada Vigilance: 2
Canada Vigilance
US FAERS
240Paranasal sinus discomfortFAERS: 1US FAERS
241Patent ductus arteriosusFAERS: 1US FAERS
242Patient restraintFAERS: 1US FAERS
243PericarditisFAERS: 1OFFSIDES
US FAERS
244PhotophobiaFAERS: 1US FAERS
245Physical assaultFAERS: 1US FAERS
246PlasmapheresisFAERS: 1US FAERS
247Poor quality drug administeredFAERS: 1US FAERS
248Product quality issueFAERS: 1US FAERS
249Product taste abnormalFAERS: 1US FAERS
250Pulmonary interstitial emphysema syndromeFAERS: 1US FAERS
251QRS axis abnormalFAERS: 1US FAERS
252RetchingFAERS: 1US FAERS
253SciaticaFAERS: 1US FAERS
254SepsisFAERS: 1US FAERS
255Small intestine carcinomaFAERS: 1US FAERS
256Somatic symptom disorder of pregnancyFAERS: 1US FAERS
257SomnambulismFAERS: 1
Canada Vigilance: 1
453369
11054994
CTD
Canada Vigilance
US FAERS
258SoporFAERS: 1US FAERS
259StressFAERS: 1US FAERS
260SubileusFAERS: 1US FAERS
261SunburnFAERS: 1US FAERS
262Supraventricular tachycardiaFAERS: 1US FAERS
263Systemic Inflammatory Response SyndromeFAERS: 1US FAERS
264TalipesFAERS: 1US FAERS
265Therapy cessationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
266Therapy changeFAERS: 1US FAERS
267Throat irritationFAERS: 1US FAERS
268Time perception alteredFAERS: 1US FAERS
269Tongue discomfortFAERS: 1US FAERS
270TorticollisFAERS: 1US FAERS
271Urinary tract obstructionFAERS: 1US FAERS
272VIIth nerve paralysisFAERS: 1OFFSIDES
US FAERS
273VasospasmFAERS: 1US FAERS
274Vulvovaginal painFAERS: 1US FAERS
275treatment failureFAERS: 1US FAERS
276Abdominal PainCanada Vigilance: 16057380CTD
OFFSIDES
Canada Vigilance
277Abdominal discomfortOFFSIDES
278Abdominal sepsisOFFSIDES
279Abnormalities, Drug-Induced6435276CTD
280AbscessOFFSIDES
281Accidental overdoseCanada Vigilance: 2Canada Vigilance
282Acid refluxOFFSIDES
283AcneOFFSIDES
284Actinic keratosisOFFSIDES
285ActinomycosisOFFSIDES
286Acute Coronary SyndromeSIDER
287Acute bronchitisOFFSIDES
288Acute myocardial infarctionOFFSIDES
289Adams-Stokes Syndrome2934037CTD
290AdenocarcinomaOFFSIDES
291AdnexitisOFFSIDES
292Affective Disorders, Psychotic6411158CTD
293AgeusiaOFFSIDES
SIDER
294AgranulocytosisSIDER
295Akathisia, Drug-Induced11075569CTD
296AkathisiaCanada Vigilance: 1Canada Vigilance
297AlveoloplastyOFFSIDES
298AmphetaminesOFFSIDES
299Amyotrophic Lateral Sclerosis2108779CTD
300AnalgesiaOFFSIDES
301Angina Pectoris9591892CTD
302Antidepressant drug level above therapeuticCanada Vigilance: 1Canada Vigilance
303Antiphospholipid antibodies positiveOFFSIDES
304Anxiety Disorders

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CTD
305Aortic AneurysmOFFSIDES
306Aortic aneurysm repairOFFSIDES
307Application site rashOFFSIDES
308ArteriosclerosisOFFSIDES
309ArthritisOFFSIDES
SIDER
310ArthropathyOFFSIDES
311Arthropod biteOFFSIDES
312Ascites6500194CTD
313Atrial FlutterOFFSIDES
314Atrial tachycardiaOFFSIDES
315Atrial thrombosisOFFSIDES
316Back disorderOFFSIDES
317Bacteria urine identifiedOFFSIDES
318Basal Ganglia Diseases11075569CTD
319Basal cell carcinomaOFFSIDES
320BedriddenOFFSIDES
321Biopsy bone abnormalOFFSIDES
322Bipolar Disorder

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CTD
OFFSIDES
323Black hairy tongueSIDER
324Blepharoptosis2530142CTD
325Blood GlucoseOFFSIDES
326Blood cholesterolOFFSIDES
327Blood creatinine increasedOFFSIDES
328Blood gases abnormalCanada Vigilance: 1Canada Vigilance
329Blood glucose decreasedOFFSIDES
330Blood human chorionic gonadotropin abnormalOFFSIDES
331Blood osmolarity decreasedOFFSIDES
332Blood sodiumOFFSIDES
333Blood testosterone decreasedOFFSIDES
334Blood thyroid stimulating hormoneOFFSIDES
335Blood triglycerides decreasedOFFSIDES
336Blurred visionOFFSIDES
337Body TemperatureOFFSIDES
338Bone density decreasedOFFSIDES
339Bone marrow depressionOFFSIDES
SIDER
340Bone painOFFSIDES
341Bowel movement irregularityOFFSIDES
342Brain Diseases8748050CTD
343Brain natriuretic peptide increasedOFFSIDES
344Breast CystOFFSIDES
345Breast tendernessCanada Vigilance: 1Canada Vigilance
346Bundle-Branch Block2004CTD
347BunionOFFSIDES
348BursitisOFFSIDES
349CalcinosisOFFSIDES
350Capgras Syndrome7076160CTD
351Cardiac FlutterCanada Vigilance: 1Canada Vigilance
352Cardiac enzymes increasedOFFSIDES
353CardiomegalyCanada Vigilance: 116040888CTD
Canada Vigilance
354Cardiomyopathy, Dilated16040888
17100146
CTD
355Cardiovascular Diseases2939838CTD
356Cardiovascular insufficiencyOFFSIDES
357Catalepsy7193623
9567763
CTD
358Cataplexy6976152CTD
359CellulitisCanada Vigilance: 1Canada Vigilance
OFFSIDES
360Cerebellar Diseases6842224CTD
361Cerebral Hemorrhage7214246CTD
362Cerebral hypoperfusionOFFSIDES
363Chemical and Drug Induced Liver Injury

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CTD
364Chemical and Drug Induced Liver Injury, Chronic3335290CTD
365Chemical cystitisOFFSIDES
366Chemotherapeutic drug level increasedOFFSIDES
367Choking sensationOFFSIDES
368Cholestasis3335290
11092117
15106034
CTD
369ChondromalaciaOFFSIDES
370Chronic Obstructive Airway DiseaseOFFSIDES
371Chronic sinusitisOFFSIDES
372Cold sweatCanada Vigilance: 1Canada Vigilance
373ColitisOFFSIDES
374Colon adenomaOFFSIDES
375Colonic StenosisOFFSIDES
376ConfabulationOFFSIDES
377Cor pulmonaleOFFSIDES
378CystOFFSIDES
379Cytoreductive SurgeryOFFSIDES
380DemyelinationOFFSIDES
381Dental cariesCanada Vigilance: 1Canada Vigilance
382Depressive disorder

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CTD
383DermatitisSIDER
384Device related infectionOFFSIDES
385DiabetesOFFSIDES
386Diabetes mellitus inadequate controlOFFSIDES
387Diabetic Neuropathies8731607
28350251
CTD
388Diabetic RetinopathyOFFSIDES
389DiarrheaOFFSIDES
390DiscomfortSIDER
391Disease recurrenceOFFSIDES
392Disorders of Excessive Somnolence2858187
4580992
6342565
CTD
393Disruptive, Impulse Control, and Conduct Disorders6458665CTD
394Disturbance in sexual arousalSIDER
395DiverticulitisOFFSIDES
396DiverticulosisOFFSIDES
397DrowsinessOFFSIDES
SIDER
398Drug Overdose

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CTD
399Drug ToleranceOFFSIDES
400Drug withdrawal headacheOFFSIDES
401Duodenal UlcerOFFSIDES
402DysgeusiaCanada Vigilance: 2Canada Vigilance
SIDER
403Dyskinesia, Drug-Induced1276554
3702925
CTD
404DysphoniaCanada Vigilance: 3Canada Vigilance
405Dyspnea4188648CTD
406Dysthymic DisorderOFFSIDES
407DystoniaCanada Vigilance: 11602323
3358469
7114327
CTD
OFFSIDES
Canada Vigilance
408EcchymosisCanada Vigilance: 1Canada Vigilance
409Edema12798668CTD
410Ejection Fraction DecreasedOFFSIDES
411Electrocardiogram QRS complexSIDER
412Electroencephalogram abnormalCanada Vigilance: 1Canada Vigilance
413Electromechanical dissociationOFFSIDES
414Emotional distressOFFSIDES
415Endocarditis910638CTD
416Endometrial cancer stage IIOFFSIDES
417Enuresis5452657
16939528
20119596
CTD
OFFSIDES
418Eosinophilia690091CTD
SIDER
419Epigastric distressSIDER
420EpiscleritisOFFSIDES
421Erythema MultiformeCanada Vigilance: 1Canada Vigilance
422Extremity contractureOFFSIDES
423Facial NeuralgiaOFFSIDES
424Fever6500194
6842224
CTD
425FibromyalgiaOFFSIDES
426Fibrosis3335290
12638679
CTD
427Fluid overloadOFFSIDES
428FormicationOFFSIDES
429Gait inabilityCanada Vigilance: 1Canada Vigilance
430GamblingOFFSIDES
431GangreneOFFSIDES
432Gastrointestinal motility disorderOFFSIDES
433Gastrointestinal stoma complicationOFFSIDES
434General physical health deteriorationOFFSIDES
435Gestational DiabetesOFFSIDES
436GlycosuriaCanada Vigilance: 1Canada Vigilance
437GoutOFFSIDES
438GranulomaOFFSIDES
439Hallucinations3351009
7468295
8562668
CTD
440Headache Disorders, Primary19085181CTD
441Hearing Loss7107155CTD
442Heart Block6028741CTD
443Heart Diseases

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CTD
444Heart failure429744
2410706
3963932
CTD
445Hematuria6703117CTD
446Hepatic Encephalopathy6500194CTD
447Hepatitis COFFSIDES
448Hepatitis1937386
12638679
CTD
SIDER
449Hepatomegaly28108177CTD
450Hepatorenal Syndrome11092117CTD
451Hoarseness7369424CTD
452Hyperalgesia

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CTD
453HyperpyrexiaSIDER
454Hypoaesthesia facialOFFSIDES
455Hyponatremia2807860
6975430
20672238
CTD
456Hypotension, Orthostatic341941
6342565
CTD
457Hypoxia12212966CTD
OFFSIDES
458Idiosyncratic drug reactionOFFSIDES
459Ileal ulcerOFFSIDES
460ImmunosuppressionOFFSIDES
461Impaired work abilityOFFSIDES
462Inappropriate schedule of drug administrationOFFSIDES
463IncontinenceOFFSIDES
464Incorrect drug administration durationOFFSIDES
465Increased upper airway secretionOFFSIDES
466InfectionOFFSIDES
467Inflammation12798668CTD
468Infrequent bowel movementsOFFSIDES
469Infusion site bruisingOFFSIDES
470Infusion site mobility decreasedOFFSIDES
471Infusion site painOFFSIDES
472Infusion site rashOFFSIDES
473Injection site drynessOFFSIDES
474Injection site erythemaOFFSIDES
475Injection site warmthOFFSIDES
476Intention tremorOFFSIDES
477Intentional drug misuseOFFSIDES
478Intervertebral disc disorderOFFSIDES
479Jaundice, Obstructive6057380
11092117
CTD
480Joint injuryOFFSIDES
481Joint stiffnessCanada Vigilance: 1Canada Vigilance
482Kidney FailureOFFSIDES
483LeukoencephalopathyOFFSIDES
484LeukopeniaSIDER
485Life expectancy shortenedOFFSIDES
486Lupus-like syndromeSIDER
487Lyme DiseaseOFFSIDES
488Lymphangiosis carcinomatosaOFFSIDES
489LymphomaOFFSIDES
490Malignant tumour excisionOFFSIDES
491MastectomyOFFSIDES
492Memory Disorders717591
2060544
CTD
493Mental disorders16856516CTD
494Mental impairmentOFFSIDES
495Middle insomniaOFFSIDES
496Migraine Disorders

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CTD
497Mitral valve sclerosisOFFSIDES
498Mood Disorders

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CTD
499Movement Disorders1971459CTD
500Multiple SclerosisOFFSIDES
501Multiple sclerosis relapseOFFSIDES
502Muscle Cramp4429931CTD
503Muscle Hypertonia7775702CTD
504Muscle RigiditySIDER
505Muscle WeaknessOFFSIDES
506Muscle tightnessOFFSIDES
507Mycobacterium avium complex immune restoration diseaseOFFSIDES
508MyelitisOFFSIDES
509Myeloma recurrenceOFFSIDES
510Myocardial Ischemia9591892CTD
511Myoclonus831550
848598
3827519
CTD
512Necrosis35109CTD
513Nephrogenic Fibrosing DermopathyOFFSIDES
514Nervous tensionOFFSIDES
515Neural Tube Defects6435276CTD
516Neuralgia

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CTD
OFFSIDES
517Neurotoxicity Syndromes16978678CTD
518Neutropenic colitisOFFSIDES
519NocturiaOFFSIDES
520NumbnessSIDER
521NystagmusOFFSIDES
522Occult blood positiveOFFSIDES
523Ocular Motility Disorders14707989
21190451
CTD
524OligomenorrheaOFFSIDES
525OliguriaOFFSIDES
526Ophthalmoplegia

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CTD
527Oral Ulcer4599813CTD
528Oral mucosal exfoliationOFFSIDES
529OsteopeniaOFFSIDES
530Pain, Postoperative8740607CTD
531Pancreatic Enzymes DecreasedCanada Vigilance: 1Canada Vigilance
532PancytopeniaSIDER
533Panic DisorderCanada Vigilance: 17446764CTD
OFFSIDES
Canada Vigilance
534Paresthesia of limbsSIDER
535Paresthesia

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CTD
536Parkinsonian Disorders3702925
15613935
CTD
537Parotid swellingSIDER
538Performance status decreasedOFFSIDES
539Peripheral Nerve Injuries22341215CTD
540Peripheral Nervous System Diseases2833464CTD
541Personality Disorders575199
3538914
CTD
542Phantom painOFFSIDES
543PharyngitisCanada Vigilance: 1Canada Vigilance
544Pharyngolaryngeal PainOFFSIDES
545PolyneuropathyOFFSIDES
546Polyradiculoneuropathy2108779
3103821
CTD
547PolyuriaCanada Vigilance: 2Canada Vigilance
548Poor peripheral circulationOFFSIDES
549Poor quality sleepCanada Vigilance: 1Canada Vigilance
550Postmenopausal bleedingOFFSIDES
551Prenatal Injuries6435276CTD
552Progesterone receptor assayOFFSIDES
553Psychomotor Agitation3702925CTD
554Psychomotor Disorders3045113
6238829
6800270
CTD
555Psychoses, Substance-Induced11841141CTD
556Psychotic Disorders6186783CTD
557Pulmonary Edema12212966CTD
558Pulmonary HypertensionOFFSIDES
559Pulmonary congestionOFFSIDES
560PurpuraSIDER
561Purulent dischargeOFFSIDES
562Radiculopathy8731607CTD
563Rash erythematousCanada Vigilance: 5Canada Vigilance
564Respiratory Distress Syndrome, Adult910638CTD
565Respiratory Insufficiency12818949CTD
566RhinitisCanada Vigilance: 1Canada Vigilance
567SarcoidosisOFFSIDES
568Schizophrenia434259CTD
569Seizures

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CTD
570Septic ShockOFFSIDES
571SequestrectomyOFFSIDES
572Sialorrhea20119596CTD
573Sinus polypOFFSIDES
574Skin lesionOFFSIDES
575Skin tightnessOFFSIDES
576Sleep Initiation and Maintenance Disorders

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CTD
577Sleep Wake Disorders

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CTD
578Somatosensory Disorders4169996
15372388
CTD
579Speech Disorders717591CTD
580Spinal column stenosisOFFSIDES
581Splenic InfarctionOFFSIDES
582SpondylolisthesisOFFSIDES
583Stereotypic Movement Disorder7193623CTD
584Stevens-Johnson SyndromeCanada Vigilance: 1Canada Vigilance
585StomatitisCanada Vigilance: 2Canada Vigilance
SIDER
586Stool analysis abnormalOFFSIDES
587StuporCanada Vigilance: 26186783CTD
Canada Vigilance
588Substance Withdrawal Syndrome

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CTD
589Substance-Related Disorders8456167CTD
590Sweat Gland Diseases35109CTD
591SwellingCanada Vigilance: 1Canada Vigilance
592Synovial CystOFFSIDES
593Tachycardia, Ventricular

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CTD
594Tardive DyskinesiaOFFSIDES
SIDER
595Taste peculiarSIDER
596Temperature regulation disorderOFFSIDES
597Therapy non-responderOFFSIDES
598ThrombocytopeniaCanada Vigilance: 1910638CTD
SIDER
Canada Vigilance
599Thrombosis910638CTD
600ThyroidectomyOFFSIDES
601Tongue spasmOFFSIDES
602Tooth LossOFFSIDES
603Torsades de Pointes

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CTD
604Unevaluable eventOFFSIDES
605Unresponsive to pain stimuliOFFSIDES
606Urinary IncontinenceCanada Vigilance: 1Canada Vigilance
607Urogenital Abnormalities6435276CTD
608Uterine CancerOFFSIDES
609Uterine contractions during pregnancyCanada Vigilance: 1Canada Vigilance
610Vascular Diseases12212966CTD
611Vascular purpuraSIDER
612Venous Thromboembolism18225961CTD
613Ventricular Dysfunction, Left6173521
16040888
CTD
614Ventricular Dysfunction

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CTD
615Vertebrobasilar InsufficiencyOFFSIDES
616VertigoCanada Vigilance: 2Canada Vigilance
617Vibration test abnormalOFFSIDES
618Viral pharyngitisOFFSIDES
619Vision Disorders2066463
5580367
6386793
CTD
620Weight Gain3882679
4580992
4599813
CTD
OFFSIDES
621Wrong technique in drug usage processOFFSIDES
622Xerostomia

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CTD
623effusionOFFSIDES
624jaundiceCanada Vigilance: 2

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CTD
SIDER
Canada Vigilance
625muscle injuryOFFSIDES
626prostatitisOFFSIDES
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