Azelaic acid
(BDJRBEYXGGNYIS-UHFFFAOYSA-N)
Structure
- SMILES
- OC(=O)CCCCCCCC(=O)O
- Type(s)
- Approved
- ATC code(s)
- D10AX03
- Molecular Formula:
- C9H16O4
- Molecular Weight:
- 188.221
- Log P:
- 1.8863
- Hydrogen Bond Acceptor:
- 4
- Hydrogen Bond Donor:
- 2
- TPSA:
- 74.6
- CAS Number(s):
- 123-99-9; 26776-28-3; 27825-99-6
Synonym(s)
1.
Azelaic acid
2.
Hydron;nonanedioate
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 117 | US FAERS | |
| 2 | Erythema | FAERS: 117 | OFFSIDES SIDER US FAERS | |
| 3 | Burning sensation | FAERS: 108 | OFFSIDES US FAERS | |
| 4 | Pruritus | FAERS: 75 | SIDER US FAERS | |
| 5 | Rosacea | FAERS: 53 | CTD US FAERS | |
| 6 | Acne | FAERS: 51 | OFFSIDES SIDER US FAERS | |
| 7 | Skin irritation | FAERS: 42 | US FAERS | |
| 8 | Application site pain | FAERS: 41 | OFFSIDES US FAERS | |
| 9 | Dry skin | FAERS: 40 | OFFSIDES SIDER US FAERS | |
| 10 | Product use issue | FAERS: 26 | US FAERS | |
| 11 | Pain | FAERS: 25 | OFFSIDES SIDER US FAERS | |
| 12 | Product quality issue | FAERS: 23 | US FAERS | |
| 13 | Application site erythema | FAERS: 20 | US FAERS | |
| 14 | Facial Pain | FAERS: 19 | US FAERS | |
| 15 | Hypersensitivity | FAERS: 18 | SIDER US FAERS | |
| 16 | Drug dose omission | FAERS: 17 | US FAERS | |
| 17 | Application site irritation | FAERS: 14 | OFFSIDES US FAERS | |
| 18 | Product container issue | FAERS: 14 | US FAERS | |
| 19 | Adverse event | FAERS: 12 | OFFSIDES US FAERS | |
| 20 | Application site dryness | FAERS: 12 | OFFSIDES US FAERS | |
| 21 | Application site pruritus | FAERS: 12 | US FAERS | |
| 22 | Pain of skin | FAERS: 12 | US FAERS | |
| 23 | Product physical consistency issue | FAERS: 12 | US FAERS | |
| 24 | Product use in unapproved indication | FAERS: 12 | US FAERS | |
| 25 | No adverse event | FAERS: 9 | US FAERS | |
| 26 | Urticaria | FAERS: 9 | US FAERS | |
| 27 | Eye irritation | FAERS: 7 | US FAERS | |
| 28 | Maternal exposure during pregnancy | FAERS: 7 | US FAERS | |
| 29 | Therapeutic response unexpected | FAERS: 7 | US FAERS | |
| 30 | Headache | FAERS: 6 | US FAERS | |
| 31 | Poor quality drug administered | FAERS: 6 | US FAERS | |
| 32 | Product physical issue | FAERS: 6 | US FAERS | |
| 33 | Rash erythematous | FAERS: 6 | US FAERS | |
| 34 | Application site burn | FAERS: 5 | US FAERS | |
| 35 | Application site rash | FAERS: 5 | OFFSIDES US FAERS | |
| 36 | Drug effect incomplete | FAERS: 5 | US FAERS | |
| 37 | Expired product administered | FAERS: 5 | US FAERS | |
| 38 | Hypertrichosis | FAERS: 5 | SIDER US FAERS | |
| 39 | Inflammation | FAERS: 5 | 18803456 20545756 | CTD US FAERS |
| 40 | Patient dissatisfaction with treatment | FAERS: 5 | US FAERS | |
| 41 | Product packaging issue | FAERS: 5 | US FAERS | |
| 42 | Thermal burn | FAERS: 5 | US FAERS | |
| 43 | Dermatitis | FAERS: 4 | SIDER US FAERS | |
| 44 | Device malfunction | FAERS: 4 | US FAERS | |
| 45 | Fatigue | FAERS: 4 | OFFSIDES US FAERS | |
| 46 | Flushing | FAERS: 4 | US FAERS | |
| 47 | Incorrect drug administration duration | FAERS: 4 | US FAERS | |
| 48 | Malaise | FAERS: 4 | US FAERS | |
| 49 | Sunburn | FAERS: 4 | US FAERS | |
| 50 | Unevaluable event | FAERS: 4 | US FAERS | |
| 51 | Wrong technique in product usage process | FAERS: 4 | US FAERS | |
| 52 | Asthma | FAERS: 3 | SIDER US FAERS | |
| 53 | Chemical burn of skin | FAERS: 3 | US FAERS | |
| 54 | Discomfort | FAERS: 3 | US FAERS | |
| 55 | Drug dispensing error | FAERS: 3 | US FAERS | |
| 56 | Dysgeusia | FAERS: 3 | US FAERS | |
| 57 | Expired drug administered | FAERS: 3 | US FAERS | |
| 58 | Eye pain | FAERS: 3 | OFFSIDES US FAERS | |
| 59 | Feeling abnormal | FAERS: 3 | US FAERS | |
| 60 | Hirsutism | FAERS: 3 | US FAERS | |
| 61 | Incorrect dose administered | FAERS: 3 | US FAERS | |
| 62 | Nausea | FAERS: 3 | OFFSIDES US FAERS | |
| 63 | Precancerous skin lesion | FAERS: 3 | US FAERS | |
| 64 | Product leakage | FAERS: 3 | US FAERS | |
| 65 | Skin tightness | FAERS: 3 | US FAERS | |
| 66 | Swelling | FAERS: 3 | US FAERS | |
| 67 | Actinic keratosis | FAERS: 2 | US FAERS | |
| 68 | Ankle Fracture | FAERS: 2 | US FAERS | |
| 69 | Application site discharge | FAERS: 2 | OFFSIDES US FAERS | |
| 70 | Application site reaction | FAERS: 2 | SIDER US FAERS | |
| 71 | Depressed mood | FAERS: 2 | US FAERS | |
| 72 | Drug effect variable | FAERS: 2 | US FAERS | |
| 73 | Drug use for unknown indication | FAERS: 2 | OFFSIDES US FAERS | |
| 74 | Economic problem | FAERS: 2 | OFFSIDES US FAERS | |
| 75 | Exfoliative rash | FAERS: 2 | US FAERS | |
| 76 | Exposure during breast feeding | FAERS: 2 | US FAERS | |
| 77 | Eye inflammation | FAERS: 2 | US FAERS | |
| 78 | Food Allergy | FAERS: 2 | US FAERS | |
| 79 | Inappropriate schedule of drug administration | FAERS: 2 | US FAERS | |
| 80 | Incorrect product administration duration | FAERS: 2 | US FAERS | |
| 81 | Intentional product misuse | FAERS: 2 | US FAERS | |
| 82 | Maternal exposure during breast feeding | FAERS: 2 | US FAERS | |
| 83 | Medication residue | FAERS: 2 | US FAERS | |
| 84 | Palpitations | FAERS: 2 | US FAERS | |
| 85 | Photodermatosis | FAERS: 2 | US FAERS | |
| 86 | Product packaging quantity issue | FAERS: 2 | US FAERS | |
| 87 | Product prescribing issue | FAERS: 2 | US FAERS | |
| 88 | Skin Wrinkling | FAERS: 2 | US FAERS | |
| 89 | Skin discomfort | FAERS: 2 | US FAERS | |
| 90 | Skin reaction | FAERS: 2 | US FAERS | |
| 91 | Stress | FAERS: 2 | OFFSIDES US FAERS | |
| 92 | Therapeutic product ineffective | FAERS: 2 | US FAERS | |
| 93 | Visual Impairment | FAERS: 2 | US FAERS | |
| 94 | Wheezing | FAERS: 2 | US FAERS | |
| 95 | Accidental exposure to product | FAERS: 1 | US FAERS | |
| 96 | Agitation | FAERS: 1 | US FAERS | |
| 97 | Application site discomfort | FAERS: 1 | US FAERS | |
| 98 | Application site exfoliation | FAERS: 1 | US FAERS | |
| 99 | Application site inflammation | FAERS: 1 | US FAERS | |
| 100 | Application site scab | FAERS: 1 | US FAERS | |
| 101 | Application site swelling | FAERS: 1 | US FAERS | |
| 102 | Application site ulcer | FAERS: 1 | US FAERS | |
| 103 | Application site vesicles | FAERS: 1 | US FAERS | |
| 104 | Arthropod sting | FAERS: 1 | US FAERS | |
| 105 | Asthenia | FAERS: 1 | OFFSIDES US FAERS | |
| 106 | Basal cell carcinoma | FAERS: 1 | US FAERS | |
| 107 | Blood bilirubin abnormal | FAERS: 1 | US FAERS | |
| 108 | Bowen's Disease | FAERS: 1 | US FAERS | |
| 109 | Cataract operation | FAERS: 1 | US FAERS | |
| 110 | Chest discomfort | FAERS: 1 | US FAERS | |
| 111 | Constipation | FAERS: 1 | US FAERS | |
| 112 | Contraindicated drug prescribed | FAERS: 1 | US FAERS | |
| 113 | Crying | FAERS: 1 | US FAERS | |
| 114 | Cystitis | FAERS: 1 | US FAERS | |
| 115 | Cyst | FAERS: 1 | US FAERS | |
| 116 | Disease recurrence | FAERS: 1 | US FAERS | |
| 117 | Dizziness | FAERS: 1 | US FAERS | |
| 118 | Drug administered at inappropriate site | FAERS: 1 | US FAERS | |
| 119 | Drug effective for unapproved indication | FAERS: 1 | US FAERS | |
| 120 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 121 | Dysphonia | FAERS: 1 | US FAERS | |
| 122 | Dysplasia | FAERS: 1 | US FAERS | |
| 123 | Eczema | FAERS: 1 | US FAERS | |
| 124 | Erythematotelangiectatic Rosacea | FAERS: 1 | US FAERS | |
| 125 | Excoriation | FAERS: 1 | US FAERS | |
| 126 | Extra dose administered | FAERS: 1 | US FAERS | |
| 127 | Eyelid Function Disorder | FAERS: 1 | US FAERS | |
| 128 | Fibromyalgia | FAERS: 1 | OFFSIDES US FAERS | |
| 129 | Flatulence | FAERS: 1 | US FAERS | |
| 130 | Formication | FAERS: 1 | OFFSIDES US FAERS | |
| 131 | Hidradenitis | FAERS: 1 | US FAERS | |
| 132 | Hordeolum | FAERS: 1 | US FAERS | |
| 133 | Incorrect product storage | FAERS: 1 | US FAERS | |
| 134 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 135 | Iodine allergy | FAERS: 1 | US FAERS | |
| 136 | Lethargy | FAERS: 1 | US FAERS | |
| 137 | Medication Error | FAERS: 1 | US FAERS | |
| 138 | Medication residue present | FAERS: 1 | US FAERS | |
| 139 | Miliaria | FAERS: 1 | US FAERS | |
| 140 | Muscle strain | FAERS: 1 | US FAERS | |
| 141 | Muscle tightness | FAERS: 1 | US FAERS | |
| 142 | Musculoskeletal stiffness | FAERS: 1 | US FAERS | |
| 143 | Nasopharyngitis | FAERS: 1 | US FAERS | |
| 144 | Neck Pain | FAERS: 1 | US FAERS | |
| 145 | Non-cardiac chest pain | FAERS: 1 | US FAERS | |
| 146 | Ocular Rosacea | FAERS: 1 | US FAERS | |
| 147 | Open wound | FAERS: 1 | US FAERS | |
| 148 | Oral mucosal eruption | FAERS: 1 | US FAERS | |
| 149 | Oral pruritus | FAERS: 1 | US FAERS | |
| 150 | Oropharyngeal pain | FAERS: 1 | US FAERS | |
| 151 | Oropharyngeal plaque | FAERS: 1 | US FAERS | |
| 152 | Pre-existing condition improved | FAERS: 1 | US FAERS | |
| 153 | Presyncope | FAERS: 1 | US FAERS | |
| 154 | Product availability issue | FAERS: 1 | US FAERS | |
| 155 | Product complaint | FAERS: 1 | US FAERS | |
| 156 | Product expiration date issue | FAERS: 1 | US FAERS | |
| 157 | Product formulation issue | FAERS: 1 | US FAERS | |
| 158 | Product outer packaging issue | FAERS: 1 | US FAERS | |
| 159 | Product substitution issue | FAERS: 1 | US FAERS | |
| 160 | Product use complaint | FAERS: 1 | US FAERS | |
| 161 | Psychological Trauma | FAERS: 1 | US FAERS | |
| 162 | Purulence | FAERS: 1 | US FAERS | |
| 163 | Rebound effect | FAERS: 1 | US FAERS | |
| 164 | Rhinalgia | FAERS: 1 | US FAERS | |
| 165 | Scab | FAERS: 1 | US FAERS | |
| 166 | Sebaceous hyperplasia | FAERS: 1 | US FAERS | |
| 167 | Skeletal dysplasia | FAERS: 1 | US FAERS | |
| 168 | Skin Ulcer | FAERS: 1 | US FAERS | |
| 169 | Skin neoplasm bleeding | FAERS: 1 | US FAERS | |
| 170 | Skin test positive | FAERS: 1 | US FAERS | |
| 171 | Squamous cell carcinoma of skin | FAERS: 1 | US FAERS | |
| 172 | Talipes | FAERS: 1 | US FAERS | |
| 173 | Tension | FAERS: 1 | US FAERS | |
| 174 | Throat irritation | FAERS: 1 | US FAERS | |
| 175 | Toothache | FAERS: 1 | US FAERS | |
| 176 | Transmission of drug via semen | FAERS: 1 | US FAERS | |
| 177 | Vitiligo | FAERS: 1 | SIDER US FAERS | |
| 178 | Wrong drug administered | FAERS: 1 | US FAERS | |
| 179 | jaundice | FAERS: 1 | US FAERS | |
| 180 | Abdominal Pain | OFFSIDES | ||
| 181 | Abdominal discomfort | OFFSIDES | ||
| 182 | Acne Vulgaris | CTD | ||
| 183 | Anorexia | OFFSIDES | ||
| 184 | Anxiety | OFFSIDES | ||
| 185 | Atherosclerosis | 19880116 | CTD | |
| 186 | Blepharoptosis | OFFSIDES | ||
| 187 | Blepharospasm | Canada Vigilance: 1 | Canada Vigilance | |
| 188 | Bruxism | OFFSIDES | ||
| 189 | Bursitis | OFFSIDES | ||
| 190 | Chromaturia | OFFSIDES | ||
| 191 | Compulsive shopping | OFFSIDES | ||
| 192 | Dermatitis, Atopic | 19804495 | CTD | |
| 193 | Diplopia | OFFSIDES | ||
| 194 | Drug withdrawal headache | OFFSIDES | ||
| 195 | Dysphasia | OFFSIDES | ||
| 196 | Feeling of body temperature change | OFFSIDES | ||
| 197 | Gambling | OFFSIDES | ||
| 198 | Gastroduodenitis | OFFSIDES | ||
| 199 | Hepatic necrosis | OFFSIDES | ||
| 200 | Hepatitis | OFFSIDES | ||
| 201 | Herpes Labialis | SIDER | ||
| 202 | Hutchinson's Melanotic Freckle | 8635147 | CTD | |
| 203 | Hyperpigmentation | 20804622 21637899 | CTD | |
| 204 | Iridocyclitis | SIDER | ||
| 205 | Keratosis pilaris | SIDER | ||
| 206 | Leukoderma | SIDER | ||
| 207 | Melanosis | 22151936 | CTD | |
| 208 | Middle insomnia | OFFSIDES | ||
| 209 | Muscle Weakness | OFFSIDES | ||
| 210 | Musculoskeletal discomfort | OFFSIDES | ||
| 211 | Nasal discomfort | OFFSIDES | ||
| 212 | Neuralgia | OFFSIDES | ||
| 213 | Oligodipsia | OFFSIDES | ||
| 214 | Phototoxicity | SIDER | ||
| 215 | Psoriasis | 20684146 | CTD | |
| 216 | Redness | SIDER | ||
| 217 | Sick Sinus Syndrome | OFFSIDES | ||
| 218 | Skeletal injury | OFFSIDES | ||
| 219 | Weight Gain | OFFSIDES | ||
| 220 | Xerosis | SIDER |
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