MetaADEDB 2.0 @ LMMD
Zanamivir
(ARAIBEBZBOPLMB-UFGQHTETSA-N)
Structure
SMILES
OC[C@H]([C@H]([C@@H]1OC(=C[C@@H]([C@H]1NC(=O)C)N=C(N)N)C(=O)O)O)O
Type(s)
Approved; Investigational
ATC code(s)
J05AH01
Molecular Formula:
C12H20N4O7
Molecular Weight:
332.310
Log P:
-1.9940
Hydrogen Bond Acceptor:
11
Hydrogen Bond Donor:
7
TPSA:
200.72
CAS Number(s):
139110-80-8
Synonym(s)
1.
Zanamivir
2.
2,3-Didehydro-2,4-Dideoxy-4-Guanidino-N-Acetyl-D-Neuraminic Acid
3.
2,3-Didehydro-2,4-Dideoxy-4-Guanidinyl-N-Acetylneuraminic Acid
4.
4-Guanidino-2,4-Dideoxy-2,3-Didehydro-N-Acetylneuraminic Acid
5.
4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic Acid
6.
4-Guanidino-Neu5Ac2en
7.
5-Acetylamino-2,6-Anhydro-4-Guanidino-3,4,5-Trideoxy-D-Galacto-Non-Enoic Acid
8.
GG 167
9.
GG-167
10.
GG167
11.
Relenza
12.
4 Guanidino 2 Deoxy 2,3 Didehydro N Acetylneuraminic Acid
13.
4 Guanidino Neu5Ac2en
14.
Acid, 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic
External Link(s)
MeSHD053243
PubChem Compound60855
BindingDB4934
50330326
ChEBI50663
CHEMBLCHEMBL222813
DrugBankDB00558
DrugCentral2859
KEGGdr:D00902
cpd:C08095
Therapeutic Target DatabaseD00NPP
D01VUZ
D04RPZ
ZINC3918138
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1OverdoseFAERS: 420OFFSIDES
US FAERS
2Drug exposure during pregnancyFAERS: 305OFFSIDES
US FAERS
3Drug exposure via breast milkFAERS: 132OFFSIDES
US FAERS
4No adverse eventFAERS: 112US FAERS
5DeliriumFAERS: 89SIDER
US FAERS
6Depressed Level of ConsciousnessFAERS: 46OFFSIDES
US FAERS
7Altered state of consciousnessFAERS: 45OFFSIDES
US FAERS
8VomitingFAERS: 34SIDER
US FAERS
9NauseaFAERS: 32SIDER
US FAERS
10AgitationFAERS: 26SIDER
US FAERS
11RestlessnessFAERS: 24US FAERS
12SyncopeFAERS: 23SIDER
US FAERS
13DizzinessFAERS: 22SIDER
US FAERS
14Abdominal PainFAERS: 20SIDER
US FAERS
15PallorFAERS: 20OFFSIDES
US FAERS
16Accidental overdoseFAERS: 19US FAERS
17Memory impairmentFAERS: 19US FAERS
18Product quality issueFAERS: 18OFFSIDES
US FAERS
19Feeling abnormalFAERS: 17OFFSIDES
SIDER
US FAERS
20Incorrect route of drug administrationFAERS: 17OFFSIDES
US FAERS
21MalaiseFAERS: 17SIDER
US FAERS
22Drug ineffectiveFAERS: 16
Canada Vigilance: 6
Canada Vigilance
US FAERS
23Anaphylactic shockFAERS: 15SIDER
US FAERS
24EpistaxisFAERS: 15OFFSIDES
US FAERS
25AmnesiaFAERS: 13OFFSIDES
US FAERS
26AsthmaFAERS: 13OFFSIDES
SIDER
US FAERS
27IncoherentFAERS: 13OFFSIDES
US FAERS
28SomnolenceFAERS: 13US FAERS
29Wrong technique in drug usage processFAERS: 13US FAERS
30CryingFAERS: 12OFFSIDES
US FAERS
31TremorFAERS: 12US FAERS
32PneumoniaFAERS: 11US FAERS
33ShockFAERS: 11SIDER
US FAERS
34Drug administration errorFAERS: 10US FAERS
35InfluenzaFAERS: 10SIDER
US FAERS
36UrticariaFAERS: 10SIDER
US FAERS
37Visual ImpairmentFAERS: 10US FAERS
38HeadacheFAERS: 9SIDER
US FAERS
39Musculoskeletal stiffnessFAERS: 9OFFSIDES
US FAERS
40Respiratory FailureFAERS: 9US FAERS
41AstheniaFAERS: 8SIDER
US FAERS
42DysgeusiaFAERS: 8OFFSIDES
US FAERS
43HypotensionFAERS: 8US FAERS
44ScreamingFAERS: 8OFFSIDES
US FAERS
45Cardiac ArrestFAERS: 7US FAERS
46EpilepsyFAERS: 7US FAERS
47Live BirthFAERS: 7OFFSIDES
US FAERS
48TinnitusFAERS: 7OFFSIDES
US FAERS
49Unresponsive to stimuliFAERS: 7US FAERS
50WheezingFAERS: 7US FAERS
51Alanine Aminotransferase IncreasedFAERS: 6US FAERS
52BronchospasmFAERS: 6
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
53EncephalitisFAERS: 6OFFSIDES
US FAERS
54Anaphylactoid ReactionFAERS: 5SIDER
US FAERS
55AnosmiaFAERS: 5OFFSIDES
US FAERS
56AnxietyFAERS: 5SIDER
US FAERS
57CyanosisFAERS: 5OFFSIDES
US FAERS
58DisorientationFAERS: 5US FAERS
59Euphoric moodFAERS: 5OFFSIDES
US FAERS
60FatigueFAERS: 5
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
61HyperventilationFAERS: 5OFFSIDES
US FAERS
62Medication ErrorFAERS: 5US FAERS
63Pharyngolaryngeal PainFAERS: 5US FAERS
64PresyncopeFAERS: 5US FAERS
65Sleep TalkingFAERS: 5OFFSIDES
US FAERS
66Stevens-Johnson SyndromeFAERS: 525811541CTD
SIDER
US FAERS
67nervous system disorderFAERS: 5US FAERS
68AngerFAERS: 4US FAERS
69AngioedemaFAERS: 4US FAERS
70AnorexiaFAERS: 4SIDER
US FAERS
71AphasiaFAERS: 4US FAERS
72ArthralgiaFAERS: 4SIDER
US FAERS
73Chest discomfortFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
74ChillsFAERS: 4SIDER
US FAERS
75Cold sweatFAERS: 4US FAERS
76DehydrationFAERS: 4SIDER
US FAERS
77Delirium febrileFAERS: 4OFFSIDES
US FAERS
78DiscomfortFAERS: 4SIDER
US FAERS
79DysphoniaFAERS: 4US FAERS
80ErythemaFAERS: 4US FAERS
81Inappropriate schedule of drug administrationFAERS: 4US FAERS
82Initial insomniaFAERS: 4OFFSIDES
US FAERS
83NystagmusFAERS: 4OFFSIDES
US FAERS
84PalpitationsFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
85Productive CoughFAERS: 4US FAERS
86PruritusFAERS: 4US FAERS
87Retrograde amnesiaFAERS: 4OFFSIDES
US FAERS
88RhabdomyolysisFAERS: 4US FAERS
89Septic ShockFAERS: 4US FAERS
90White blood cell count decreasedFAERS: 4US FAERS
91Acute kidney injuryFAERS: 3US FAERS
92Aspartate Aminotransferase IncreasedFAERS: 3US FAERS
93Chest PainFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
94DeafnessFAERS: 3US FAERS
95Dissociative disorderFAERS: 3OFFSIDES
US FAERS
96DysarthriaFAERS: 3US FAERS
97Ear discomfortFAERS: 3US FAERS
98Erythema MultiformeFAERS: 3OFFSIDES
SIDER
US FAERS
99Febrile NeutropeniaFAERS: 3US FAERS
100Incorrect dose administeredFAERS: 3US FAERS
101Mental impairmentFAERS: 3US FAERS
102Muscle RigidityFAERS: 3US FAERS
103Oculomucocutaneous syndromeFAERS: 3US FAERS
104Oropharyngeal painFAERS: 3US FAERS
105PainFAERS: 3SIDER
US FAERS
106Pericardial effusionFAERS: 3US FAERS
107Poor quality sleepFAERS: 3OFFSIDES
US FAERS
108Respiratory distressFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
109Restless Legs SyndromeFAERS: 3US FAERS
110SomnambulismFAERS: 3US FAERS
111Urinary IncontinenceFAERS: 3US FAERS
112Viral myocarditisFAERS: 3US FAERS
113Abdominal discomfortFAERS: 2US FAERS
114Accidental exposureFAERS: 2US FAERS
115AgeusiaFAERS: 2US FAERS
116Back PainFAERS: 2US FAERS
117Blood alkaline phosphatase increasedFAERS: 2US FAERS
118Blood creatine phosphokinase increasedFAERS: 2US FAERS
119Blood lactate dehydrogenase increasedFAERS: 2US FAERS
120Body TemperatureFAERS: 2OFFSIDES
US FAERS
121BradycardiaFAERS: 2US FAERS
122BronchitisFAERS: 2SIDER
US FAERS
123ChokingFAERS: 2US FAERS
124ConjunctivitisFAERS: 2US FAERS
125Cytolytic hepatitisFAERS: 2OFFSIDES
US FAERS
126Disseminated Intravascular CoagulationFAERS: 2US FAERS
127Drug label confusionFAERS: 2US FAERS
128Electrocardiogram abnormalFAERS: 2US FAERS
129Eye painFAERS: 2US FAERS
130Feeling ColdFAERS: 2US FAERS
131FlatulenceFAERS: 2US FAERS
132Foaming at mouthFAERS: 2US FAERS
133GastroenteritisFAERS: 2OFFSIDES
US FAERS
134General physical health deteriorationFAERS: 2US FAERS
135HypoxiaFAERS: 2US FAERS
136IncontinenceFAERS: 2OFFSIDES
US FAERS
137KetosisFAERS: 2US FAERS
138LaryngospasmFAERS: 2US FAERS
139LeukopeniaFAERS: 2US FAERS
140Low birth weight babyFAERS: 2US FAERS
141Medication residueFAERS: 2US FAERS
142Middle insomniaFAERS: 2OFFSIDES
US FAERS
143MonoplegiaFAERS: 2OFFSIDES
US FAERS
144Muscle strainFAERS: 2OFFSIDES
US FAERS
145MyalgiaFAERS: 2SIDER
US FAERS
146Nasal discomfortFAERS: 2US FAERS
147Neuromyelitis OpticaFAERS: 2US FAERS
148Oral painFAERS: 2US FAERS
149Pharyngeal lesionFAERS: 2US FAERS
150PneumothoraxFAERS: 2US FAERS
151Pulmonary FibrosisFAERS: 2US FAERS
152SepsisFAERS: 2US FAERS
153Sinus bradycardiaFAERS: 2OFFSIDES
US FAERS
154StaringFAERS: 2OFFSIDES
US FAERS
155StillbirthFAERS: 2US FAERS
156StuporFAERS: 2US FAERS
157Suicide attemptFAERS: 2US FAERS
158TachycardiaFAERS: 2US FAERS
159TrismusFAERS: 2US FAERS
160Unevaluable eventFAERS: 2US FAERS
161Vestibular NeuronitisFAERS: 2OFFSIDES
US FAERS
162Abnormal clotting factorFAERS: 1OFFSIDES
US FAERS
163Accidental underdoseFAERS: 1US FAERS
164Acute respiratory failureFAERS: 1US FAERS
165Angina PectorisFAERS: 1US FAERS
166ApathyFAERS: 1US FAERS
167AppendicitisFAERS: 1US FAERS
168ArthropathyFAERS: 1US FAERS
169AstigmatismFAERS: 1OFFSIDES
US FAERS
170Atrial FibrillationFAERS: 1US FAERS
171Bipolar DisorderFAERS: 1US FAERS
172BlepharospasmFAERS: 1US FAERS
173Blood creatinine increasedFAERS: 1US FAERS
174Body temperature fluctuationFAERS: 1OFFSIDES
US FAERS
175Brain ContusionFAERS: 1US FAERS
176Bronchopleural FistulaFAERS: 1US FAERS
177Bronchopulmonary AspergillosisFAERS: 1US FAERS
178BruxismFAERS: 1OFFSIDES
US FAERS
179Cardiac valve vegetationFAERS: 1US FAERS
180Central nervous system lesionFAERS: 1US FAERS
181Cerebral disorderFAERS: 1US FAERS
182Cerebral vasoconstrictionFAERS: 1US FAERS
183Cerebrovascular accidentFAERS: 1US FAERS
184CholecystitisFAERS: 1US FAERS
185ChorioamnionitisFAERS: 1US FAERS
186ColitisFAERS: 1US FAERS
187Completed SuicideFAERS: 1US FAERS
188Congenital hydronephrosisFAERS: 1US FAERS
189Conversion disorderFAERS: 1US FAERS
190Dark circles under eyesFAERS: 1US FAERS
191Depressed moodFAERS: 1US FAERS
192Device occlusionFAERS: 1US FAERS
193Diabetes MellitusFAERS: 1US FAERS
194DiplopiaFAERS: 1US FAERS
195Disease ProgressionFAERS: 1US FAERS
196DissociationFAERS: 1US FAERS
197Drug dispensing errorFAERS: 1US FAERS
198Drug dose omissionFAERS: 1US FAERS
199Dry skinFAERS: 1US FAERS
200EczemaFAERS: 1US FAERS
201Electroencephalogram abnormalFAERS: 1US FAERS
202EnuresisFAERS: 1US FAERS
203Expired drug administeredFAERS: 1US FAERS
204Expired product administeredFAERS: 1US FAERS
205Exposure during breast feedingFAERS: 1US FAERS
206Facial PainFAERS: 1US FAERS
207FlushingFAERS: 1US FAERS
208FractureFAERS: 1US FAERS
209Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
210Gaze palsyFAERS: 1US FAERS
211Granulocyte count decreasedFAERS: 1US FAERS
212Guillain-Barre SyndromeFAERS: 1US FAERS
213HaematotoxicityFAERS: 1US FAERS
214Hallucinations, mixedFAERS: 1US FAERS
215Head titubationFAERS: 1US FAERS
216HyperacusisFAERS: 1US FAERS
217HypersensitivityFAERS: 1SIDER
US FAERS
218HyperthyroidismFAERS: 1US FAERS
219Hypoaesthesia facialFAERS: 1OFFSIDES
US FAERS
220Hyporesponsive to stimuliFAERS: 1US FAERS
221Immune thrombocytopenic purpuraFAERS: 1US FAERS
222ImpetigoFAERS: 1US FAERS
223Inappropriate affectFAERS: 1US FAERS
224IndurationFAERS: 1US FAERS
225InfectionFAERS: 1SIDER
US FAERS
226InflammationFAERS: 1US FAERS
227Intercepted drug administration errorFAERS: 1US FAERS
228LacerationFAERS: 1OFFSIDES
US FAERS
229Leucine aminopeptidase increasedFAERS: 1OFFSIDES
US FAERS
230LeukodermaFAERS: 1US FAERS
231Mechanical ventilationFAERS: 1US FAERS
232MeningitisFAERS: 1US FAERS
233Mental status changesFAERS: 1US FAERS
234Metabolic acidosisFAERS: 1US FAERS
235Miller Fisher SyndromeFAERS: 1US FAERS
236MoaningFAERS: 1OFFSIDES
US FAERS
237Mood swingsFAERS: 1US FAERS
238Multiple PregnancyFAERS: 1US FAERS
239Multiple use of single-use productFAERS: 1US FAERS
240MyelitisFAERS: 1US FAERS
241MyopathyFAERS: 1US FAERS
242Neck PainFAERS: 1US FAERS
243Nerve injuryFAERS: 1US FAERS
244NeutropeniaFAERS: 1SIDER
US FAERS
245Neutrophil count decreasedFAERS: 1US FAERS
246Nipple painFAERS: 1US FAERS
247Nonspecific reactionFAERS: 1US FAERS
248Obsessive thoughtsFAERS: 1US FAERS
249Oropharyngeal discomfortFAERS: 1US FAERS
250PancytopeniaFAERS: 1US FAERS
251Personality ChangeFAERS: 1US FAERS
252Physical assaultFAERS: 1US FAERS
253PleurisyFAERS: 1US FAERS
254Pneumococcal sepsisFAERS: 1US FAERS
255PoriomaniaFAERS: 1OFFSIDES
US FAERS
256Protein urine presentFAERS: 1US FAERS
257Psychiatric symptomFAERS: 1OFFSIDES
US FAERS
258Pulmonary EmbolismFAERS: 1US FAERS
259Radioallergosorbent test positiveFAERS: 1US FAERS
260Rash erythematousFAERS: 1US FAERS
261Renal Cell CarcinomaFAERS: 1US FAERS
262Renal tubular necrosisFAERS: 1OFFSIDES
US FAERS
263SchizophreniaFAERS: 1US FAERS
264Septic embolusFAERS: 1US FAERS
265Single functional kidneyFAERS: 1US FAERS
266Sleep ParalysisFAERS: 1OFFSIDES
US FAERS
267Staphylococcus test positiveFAERS: 1US FAERS
268Status EpilepticusFAERS: 1US FAERS
269StomatitisFAERS: 1US FAERS
270SuperinfectionFAERS: 1US FAERS
271Supraventricular tachycardiaFAERS: 1US FAERS
272TalipesFAERS: 1US FAERS
273Therapeutic response unexpectedFAERS: 1US FAERS
274Therapy cessationFAERS: 1US FAERS
275Throat irritationFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
276ThrombocytopeniaFAERS: 1US FAERS
277ThrombocytosisFAERS: 1US FAERS
278Transaminases increasedFAERS: 1US FAERS
279Vascular painFAERS: 1US FAERS
280jaundiceFAERS: 1US FAERS
281Abnormal visionOFFSIDES
282Alcoholic IntoxicationOFFSIDES
283AscitesOFFSIDES
284AuraOFFSIDES
285Beta 2 microglobulin urine increasedOFFSIDES
286Blood fibrinogenOFFSIDES
287Blood lactate dehydrogenase abnormalOFFSIDES
288Blurred visionOFFSIDES
289Cell DeathOFFSIDES
290Coagulation test abnormalOFFSIDES
291Color blindnessOFFSIDES
292DermatitisSIDER
293Elevated moodOFFSIDES
294Gastric mucosal lesionOFFSIDES
295Gastrointestinal PainSIDER
296Hepatic vein occlusionOFFSIDES
297Herpes simplex hepatitisOFFSIDES
298HypervigilanceOFFSIDES
299HyporeflexiaOFFSIDES
300Influenza-like symptomsSIDER
301Lip exfoliationOFFSIDES
302LymphopeniaSIDER
303MetrorrhagiaCanada Vigilance: 1Canada Vigilance
304Musculoskeletal PainSIDER
305Musculoskeletal discomfortSIDER
306MutismOFFSIDES
307Nasal inflammationSIDER
308Neonatal respiratory failureOFFSIDES
309Oral mucosal erythemaOFFSIDES
310Oropharyngeal swellingSIDER
311Platelet count abnormalOFFSIDES
312Pulmonary InfarctionOFFSIDES
313Retrograde portal vein flowOFFSIDES
314Rheumatic disorderSIDER
315RheumatismSIDER
316Rhinovirus infectionOFFSIDES
317SinusitisSIDER
318Toxic Epidermal NecrolysisSIDER
319UlcerOFFSIDES
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