MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Nortriptyline

(PHVGLTMQBUFIQQ-UHFFFAOYSA-N)

Structure

SMILES: CNCCC=C1c2ccccc2CCc2c1cccc2
Type(s): Approved
ATC code(s): N06AA10
Molecular Formula:: C19H21N
Molecular Weight:: 263.377
Log P:: 4.2173
Hydrogen Bond Acceptor:: 1
Hydrogen Bond Donor:: 1
TPSA:: 12.03
CAS Number(s):: 72-69-5; 894-71-3

Synonym(s)

Nortriptyline

Desitriptyline

Desmethylamitriptylin

Allegron

Apo-Nortriptyline

Aventyl

Gen-Nortriptyline

Norfenazin

Nortrilen

10.

Nortriptyline Hydrochloride

11.

Novo-Nortriptyline

12.

Nu-Nortriptyline

13.

PMS-Nortriptyline

14.

Pamelor

15.

Paxtibi

16.

ratio-Nortriptyline

17.

Apo Nortriptyline

18.

Gen Nortriptyline

19.

Hydrochloride, Nortriptyline

20.

Novo Nortriptyline

21.

Nu Nortriptyline

22.

PMS Nortriptyline

23.

ratio Nortriptyline

External Link(s)

MeSH	D009661
PubChem Compound	4543
BindingDB	112777 50020710
ChEBI	7640
CHEMBL	CHEMBL445
DrugBank	DB00540
DrugCentral	1971
IUPHAR/BPS Guide to PHARMACOLOGY	2404
KEGG	cpd:C07274 dr:D08288
Therapeutic Target Database	D04WFD
ZINC	1530741

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Completed Suicide	FAERS: 27 Canada Vigilance: 2		Canada Vigilance OFFSIDES US FAERS
2	Toxicity to various agents	FAERS: 13		US FAERS
3	Drug ineffective	FAERS: 12 Canada Vigilance: 4		Canada Vigilance OFFSIDES US FAERS
4	Overdose	FAERS: 9		OFFSIDES US FAERS
5	Headache	FAERS: 8 Canada Vigilance: 4	7294224	CTD SIDER Canada Vigilance US FAERS
6	Anger	FAERS: 7 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
7	Dizziness	FAERS: 7 Canada Vigilance: 4	2008540 8444823 12098632	CTD OFFSIDES SIDER Canada Vigilance US FAERS
8	Hypersensitivity	FAERS: 7		SIDER US FAERS
9	Tachycardia	FAERS: 7	View details 375687 1810269 6759061 9699704 11673748	CTD SIDER US FAERS
10	Agitation	FAERS: 6 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
11	Anxiety	FAERS: 6 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
12	Cardiac Arrest	FAERS: 6		US FAERS
13	Feeling abnormal	FAERS: 6		OFFSIDES SIDER US FAERS
14	Hypotension	FAERS: 6 Canada Vigilance: 1	8031432	CTD SIDER Canada Vigilance US FAERS
15	Nausea	FAERS: 6 Canada Vigilance: 4		Canada Vigilance OFFSIDES SIDER US FAERS
16	Palpitations	FAERS: 6 Canada Vigilance: 3		Canada Vigilance SIDER US FAERS
17	Product use in unapproved indication	FAERS: 6		US FAERS
18	Abdominal discomfort	FAERS: 5 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
19	Pruritus	FAERS: 5 Canada Vigilance: 4		Canada Vigilance SIDER US FAERS
20	Somnolence	FAERS: 5 Canada Vigilance: 4		Canada Vigilance SIDER US FAERS
21	Tremor	FAERS: 5 Canada Vigilance: 5	10435776 11673748	CTD SIDER Canada Vigilance US FAERS
22	Burning sensation	FAERS: 4 Canada Vigilance: 2		Canada Vigilance US FAERS
23	Constipation	FAERS: 4 Canada Vigilance: 1	View details 3756264 6759061 12098632 19721108	CTD SIDER Canada Vigilance US FAERS
24	Lethargy	FAERS: 4		OFFSIDES US FAERS
25	Medication Error	FAERS: 4		US FAERS
26	Nervousness	FAERS: 4 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
27	Pain	FAERS: 4		OFFSIDES US FAERS
28	Pharmaceutical product complaint	FAERS: 4		OFFSIDES US FAERS
29	Product quality issue	FAERS: 4		OFFSIDES US FAERS
30	Product substitution issue	FAERS: 4 Canada Vigilance: 2		Canada Vigilance US FAERS
31	Syncope	FAERS: 4 Canada Vigilance: 2	5470429 15669899	CTD SIDER Canada Vigilance US FAERS
32	Therapeutic response unexpected	FAERS: 4 Canada Vigilance: 1		Canada Vigilance US FAERS
33	Ventricular Fibrillation	FAERS: 4		SIDER US FAERS
34	Abdominal Pain	FAERS: 3 Canada Vigilance: 3		Canada Vigilance OFFSIDES SIDER US FAERS
35	Amnesia	FAERS: 3		OFFSIDES US FAERS
36	Chest Pain	FAERS: 3		OFFSIDES US FAERS
37	Depressed mood	FAERS: 3		OFFSIDES US FAERS
38	Drug ineffective for unapproved indication	FAERS: 3		US FAERS
39	Drug level increased	FAERS: 3		US FAERS
40	Drug prescribing error	FAERS: 3		US FAERS
41	Dyspepsia	FAERS: 3 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
42	Fatigue	FAERS: 3 Canada Vigilance: 2	11673748	CTD OFFSIDES SIDER Canada Vigilance US FAERS
43	Paranoia	FAERS: 3		OFFSIDES US FAERS
44	Product taste abnormal	FAERS: 3		US FAERS
45	Product use issue	FAERS: 3		US FAERS
46	Respiratory arrest	FAERS: 3		US FAERS
47	Vomiting	FAERS: 3		SIDER US FAERS
48	Activities of daily living impaired	FAERS: 2		US FAERS
49	Adverse event	FAERS: 2		US FAERS
50	Alopecia	FAERS: 2 Canada Vigilance: 5		Canada Vigilance OFFSIDES SIDER US FAERS
51	Arthralgia	FAERS: 2		US FAERS
52	Asthenia	FAERS: 2		OFFSIDES SIDER US FAERS
53	Bipolar Disorder	FAERS: 2	7893862 10435776 11673748	CTD OFFSIDES US FAERS
54	Craniosynostosis	FAERS: 2		OFFSIDES US FAERS
55	Deafness Neurosensory	FAERS: 2		OFFSIDES US FAERS
56	Discomfort	FAERS: 2		SIDER US FAERS
57	Disorientation	FAERS: 2		SIDER US FAERS
58	Drug dispensing error	FAERS: 2		US FAERS
59	Drug exposure during pregnancy	FAERS: 2		OFFSIDES US FAERS
60	Dysarthria	FAERS: 2		US FAERS
61	Electrocardiogram abnormal	FAERS: 2		US FAERS
62	Emotional disorder	FAERS: 2		OFFSIDES US FAERS
63	Eye pain	FAERS: 2 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
64	Incorrect dose administered	FAERS: 2		US FAERS
65	Mental status changes	FAERS: 2		OFFSIDES US FAERS
66	Middle insomnia	FAERS: 2		OFFSIDES US FAERS
67	Product physical issue	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
68	Unmasking of previously unidentified disease	FAERS: 2		US FAERS
69	Weight decreased	FAERS: 2 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
70	Acute respiratory failure	FAERS: 1		US FAERS
71	Alcohol abuse	FAERS: 1		OFFSIDES US FAERS
72	Angioedema	FAERS: 1		US FAERS
73	Apparent death	FAERS: 1		OFFSIDES US FAERS
74	Asphyxia	FAERS: 1		OFFSIDES US FAERS
75	Ataxia	FAERS: 1		OFFSIDES SIDER US FAERS
76	Atrial Fibrillation	FAERS: 1		US FAERS
77	Atrioventricular Block	FAERS: 1		SIDER US FAERS
78	Blood creatinine increased	FAERS: 1		OFFSIDES US FAERS
79	Blood pressure fluctuation	FAERS: 1		US FAERS
80	Blood urea increased	FAERS: 1		US FAERS
81	Blood urine present	FAERS: 1		US FAERS
82	Cardiotoxicity	FAERS: 1		US FAERS
83	Crying	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
84	Cyanosis	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
85	Deafness	FAERS: 1		OFFSIDES US FAERS
86	Delirium	FAERS: 1		SIDER US FAERS
87	Depressed Level of Consciousness	FAERS: 1		US FAERS
88	Diplopia	FAERS: 1		OFFSIDES US FAERS
89	Disease Progression	FAERS: 1		OFFSIDES US FAERS
90	Disease recurrence	FAERS: 1		OFFSIDES US FAERS
91	Drug effect incomplete	FAERS: 1		US FAERS
92	Dry skin	FAERS: 1		US FAERS
93	Dysgeusia	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES SIDER US FAERS
94	Dysphonia	FAERS: 1		OFFSIDES US FAERS
95	Dysuria	FAERS: 1		OFFSIDES US FAERS
96	Eructation	FAERS: 1		US FAERS
97	Erythema	FAERS: 1		OFFSIDES US FAERS
98	Essential Tremor	FAERS: 1		US FAERS
99	Euphoric mood	FAERS: 1		OFFSIDES US FAERS
100	Exposure via ingestion	FAERS: 1		US FAERS
101	Eye irritation	FAERS: 1		US FAERS
102	Feeling jittery	FAERS: 1		US FAERS
103	Flushing	FAERS: 1		SIDER US FAERS
104	Gastrointestinal Pain	FAERS: 1		US FAERS
105	Gastrointestinal hypomotility	FAERS: 1		US FAERS
106	Gluten sensitivity	FAERS: 1		US FAERS
107	Hydrocephalus	FAERS: 1		US FAERS
108	Hypersomnia	FAERS: 1		US FAERS
109	Hyperventilation	FAERS: 1		US FAERS
110	Idiopathic angioedema	FAERS: 1		US FAERS
111	Impaired driving ability	FAERS: 1		OFFSIDES US FAERS
112	Impaired gastric emptying	FAERS: 1		OFFSIDES US FAERS
113	Influenza	FAERS: 1		US FAERS
114	Intentional drug misuse	FAERS: 1		OFFSIDES US FAERS
115	Intentional product misuse	FAERS: 1		US FAERS
116	Lack of spontaneous speech	FAERS: 1		US FAERS
117	Malaise	FAERS: 1		SIDER US FAERS
118	Memory impairment	FAERS: 1		US FAERS
119	Mood swings	FAERS: 1		US FAERS
120	Myalgia	FAERS: 1		US FAERS
121	Nasopharyngitis	FAERS: 1		US FAERS
122	Nerve injury	FAERS: 1		US FAERS
123	Neuralgia	FAERS: 1		OFFSIDES US FAERS
124	No reaction on previous exposure to drug	FAERS: 1		US FAERS
125	Ocular discomfort	FAERS: 1		US FAERS
126	Optic Neuritis	FAERS: 1		US FAERS
127	Papule	FAERS: 1		US FAERS
128	Parasomnia	FAERS: 1		US FAERS
129	Partner stress	FAERS: 1		US FAERS
130	Physical abuse	FAERS: 1		US FAERS
131	Physical product label issue	FAERS: 1		US FAERS
132	Pityriasis Rosea	FAERS: 1		US FAERS
133	Pneumonia	FAERS: 1		US FAERS
134	Poisoning	FAERS: 1		US FAERS
135	Porencephaly	FAERS: 1		US FAERS
136	Presyncope	FAERS: 1		US FAERS
137	Product dispensing error	FAERS: 1		US FAERS
138	QRS axis abnormal	FAERS: 1		OFFSIDES US FAERS
139	Reaction to drug excipients	FAERS: 1		US FAERS
140	Sepsis	FAERS: 1		US FAERS
141	Sexual Dysfunction	FAERS: 1		US FAERS
142	Sinus Tachycardia	FAERS: 1		US FAERS
143	Skin reaction	FAERS: 1		US FAERS
144	Sleep Talking	FAERS: 1		US FAERS
145	Sleep sex	FAERS: 1		US FAERS
146	Sleep-related eating disorder	FAERS: 1		US FAERS
147	Somnambulism	FAERS: 1		US FAERS
148	Status Epilepticus	FAERS: 1		US FAERS
149	Stupor	FAERS: 1		US FAERS
150	Sudden Cardiac Death	FAERS: 1		US FAERS
151	Suicide attempt	FAERS: 1		US FAERS
152	Systemic Inflammatory Response Syndrome	FAERS: 1		US FAERS
153	Tachyphrenia	FAERS: 1		US FAERS
154	Tetany	FAERS: 1		US FAERS
155	Therapeutic product effect delayed	FAERS: 1		US FAERS
156	Therapeutic response unexpected with drug substitution	FAERS: 1		OFFSIDES US FAERS
157	Throat irritation	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
158	Tinnitus	FAERS: 1 Canada Vigilance: 5		Canada Vigilance SIDER US FAERS
159	Unresponsive to stimuli	FAERS: 1		OFFSIDES US FAERS
160	Urinary hesitation	FAERS: 1		US FAERS
161	Visual Impairment	FAERS: 1 Canada Vigilance: 2		Canada Vigilance US FAERS
162	Vitreous Detachment	FAERS: 1		US FAERS
163	Vulvovaginal discomfort	FAERS: 1		US FAERS
164	Vulvovaginal mycotic infection	FAERS: 1		US FAERS
165	Walking aid user	FAERS: 1		OFFSIDES US FAERS
166	treatment failure	FAERS: 1		US FAERS
167	Abasia			OFFSIDES
168	Abdominal Abscess			OFFSIDES
169	Abdominal Cramps			SIDER
170	Abdominal adhesions			OFFSIDES
171	Abnormal cervical smear			OFFSIDES
172	Abnormal vision			OFFSIDES
173	Abuse			OFFSIDES
174	Accidental death			OFFSIDES
175	Accidental overdose	Canada Vigilance: 1		Canada Vigilance
176	Acid reflux			OFFSIDES
177	Acne	Canada Vigilance: 1		Canada Vigilance
178	Acquired Protein S Deficiency			OFFSIDES
179	Acromegaly			OFFSIDES
180	Actinomycosis			OFFSIDES
181	Activation syndrome			OFFSIDES
182	Acute Coronary Syndrome			OFFSIDES SIDER
183	Acute bronchitis			OFFSIDES
184	Acute myocardial infarction			OFFSIDES
185	Acute otitis media			OFFSIDES
186	Adams-Stokes Syndrome		6028741	CTD
187	Adenitis			SIDER
188	Adenoma			OFFSIDES
189	Adrenal mass			OFFSIDES
190	Affective Disorders, Psychotic		7893862	CTD
191	Agranulocytosis	Canada Vigilance: 1		Canada Vigilance SIDER
192	Agraphia			OFFSIDES
193	Alanine Aminotransferase Increased	Canada Vigilance: 1		Canada Vigilance
194	Alcohol consumption			OFFSIDES
195	Alcohol poisoning			OFFSIDES
196	Alcoholic Intoxication			OFFSIDES
197	Allergy to arthropod sting			OFFSIDES
198	Alpha 2 globulin increased			OFFSIDES
199	Alveolitis			OFFSIDES
200	Amblyopia			OFFSIDES
201	Amenorrhea			OFFSIDES
202	Amphetamines			OFFSIDES
203	Amyotrophic Lateral Sclerosis		17686041	CTD
204	Anal candidiasis			OFFSIDES
205	Analgesia			OFFSIDES
206	Androgens increased	Canada Vigilance: 1		Canada Vigilance
207	Aneurysm			OFFSIDES
208	Angle Closure Glaucoma			SIDER
209	Anhedonia			OFFSIDES
210	Anhidrosis			OFFSIDES
211	Anorexia			OFFSIDES SIDER
212	Anosmia			OFFSIDES
213	Anti-erythropoietin antibody positive			OFFSIDES
214	Antidepressant drug level above therapeutic			OFFSIDES
215	Antidepressant drug level increased			OFFSIDES
216	Aortic valve sclerosis			OFFSIDES
217	Apathy			OFFSIDES
218	Aphonia		507219	CTD OFFSIDES
219	Aphthous Stomatitis			OFFSIDES
220	Application site pain			OFFSIDES
221	Application site rash			OFFSIDES
222	Arteriosclerosis			OFFSIDES
223	Arteriovenous fistula			OFFSIDES
224	Arthritis			OFFSIDES
225	Aspiration Pneumonia			OFFSIDES
226	Asthma			OFFSIDES
227	Atelectasis			OFFSIDES
228	Atrial tachycardia			OFFSIDES
229	Aura			OFFSIDES
230	Autoimmune thyroiditis			OFFSIDES
231	Autologous bone marrow transplantation therapy			OFFSIDES
232	Back Pain		20306168	CTD
233	Back disorder			OFFSIDES
234	Bacterial Endocarditis			OFFSIDES
235	Basal Ganglia Diseases		2889 10435776	CTD
236	Basal cell carcinoma			OFFSIDES
237	Benign Prostatic Hyperplasia			OFFSIDES
238	Benign breast lump removal			OFFSIDES
239	Bereavement			OFFSIDES
240	Biopsy muscle abnormal			OFFSIDES
241	Biopsy			OFFSIDES
242	Bipolar I disorder			OFFSIDES
243	Black hairy tongue			SIDER
244	Bladder neck obstruction			OFFSIDES
245	Bladder prolapse			OFFSIDES
246	Blepharoptosis			OFFSIDES
247	Blepharospasm			OFFSIDES
248	Blood 1,25-dihydroxycholecalciferol decreased			OFFSIDES
249	Blood Glucose			OFFSIDES
250	Blood albumin decreased			OFFSIDES
251	Blood alkaline phosphatase increased	Canada Vigilance: 1		Canada Vigilance
252	Blood bilirubin unconjugated increased			OFFSIDES
253	Blood chloride decreased			OFFSIDES
254	Blood chloride increased			OFFSIDES
255	Blood creatine decreased			OFFSIDES
256	Blood creatinine decreased			OFFSIDES
257	Blood electrolytes abnormal			OFFSIDES
258	Blood glucose decreased			OFFSIDES
259	Blood glucose fluctuation			OFFSIDES
260	Blood immunoglobulin G increased			OFFSIDES
261	Blood immunoglobulin M			OFFSIDES
262	Blood magnesium increased			OFFSIDES
263	Blood pH increased			OFFSIDES
264	Blood parathyroid hormone increased			OFFSIDES
265	Blood potassium decreased	Canada Vigilance: 1		Canada Vigilance
266	Blood potassium increased			OFFSIDES
267	Blood pressure inadequately controlled			OFFSIDES
268	Blood sodium increased			OFFSIDES
269	Blood thyroid stimulating hormone	Canada Vigilance: 1		Canada Vigilance
270	Blurred vision			OFFSIDES
271	Bone abscess			OFFSIDES
272	Bone density decreased			OFFSIDES
273	Bone erosion			OFFSIDES
274	Bone marrow depression			SIDER
275	Bone pain			OFFSIDES
276	Bowel movement irregularity			OFFSIDES
277	Bradycardia		6028741	CTD
278	Brain Concussion			OFFSIDES
279	Brain Death			OFFSIDES
280	Brain natriuretic peptide increased			OFFSIDES
281	Brain scan abnormal			OFFSIDES
282	Breakthrough Pain			OFFSIDES
283	Breast Microcalcification			OFFSIDES
284	Breast hyperplasia			OFFSIDES
285	Breast tenderness			OFFSIDES
286	Bronchial secretion retention			OFFSIDES
287	Bronchial wall thickening			OFFSIDES
288	Bronchitis			OFFSIDES
289	Bruxism			OFFSIDES
290	Bulbar palsy			OFFSIDES
291	Bundle-Branch Block		2004 1918772 5470429	CTD
292	Bursitis			OFFSIDES
293	Cancer Pain			OFFSIDES
294	Cardiac Flutter			OFFSIDES
295	Cardiac Hypertrophy			OFFSIDES
296	Cardiac asthma			OFFSIDES
297	Cardiac stress test abnormal			OFFSIDES
298	Cardioactive drug level increased			OFFSIDES
299	Cardiovascular Diseases		9585718	CTD
300	Carotid artery occlusion			OFFSIDES
301	Catalepsy		9567763	CTD
302	Cataract			OFFSIDES
303	Catheter placement			OFFSIDES
304	Cerebellar infarction			OFFSIDES
305	Cerebral Arteriosclerosis			OFFSIDES
306	Cerebral artery occlusion			OFFSIDES
307	Cerebral atrophy			OFFSIDES
308	Cerebral cyst			OFFSIDES
309	Cerebral vasoconstriction			OFFSIDES
310	Cerebrovascular accident			SIDER
311	Ceruloplasmin decreased			OFFSIDES
312	Cervical dysplasia			OFFSIDES
313	Cervical polyp			OFFSIDES
314	Cervicobrachial syndrome			OFFSIDES
315	Cervix carcinoma recurrent			OFFSIDES
316	Chemical and Drug Induced Liver Injury		8848811 28437613	CTD
317	Chemotherapeutic drug level increased			OFFSIDES
318	Chills	Canada Vigilance: 1		Canada Vigilance
319	Choking sensation			OFFSIDES
320	Choking			OFFSIDES
321	Cholecystitis			OFFSIDES
322	Cholestasis			SIDER
323	Chondroplasty			OFFSIDES
324	Chromatopsia			OFFSIDES
325	Chronic Fatigue Syndrome			OFFSIDES
326	Chronic Obstructive Airway Disease			OFFSIDES
327	Cirrhosis			OFFSIDES
328	Citrobacter infection			OFFSIDES
329	Clostridium colitis			OFFSIDES
330	Clostridium difficile colitis			OFFSIDES
331	Clostridium difficile toxin test positive			OFFSIDES
332	Clumsiness			SIDER
333	Cluster Headache			OFFSIDES
334	Coagulation factor VIII level increased			OFFSIDES
335	Cognition Disorders		1390620 1734612	CTD
336	Colectomy			OFFSIDES
337	Colonic Stenosis			OFFSIDES
338	Compression fracture			OFFSIDES
339	Compulsive shopping			OFFSIDES
340	Concomitant disease aggravated			OFFSIDES
341	Confabulation			OFFSIDES
342	Congenital tricuspid valve incompetence			OFFSIDES
343	Corneal Ulcer			OFFSIDES
344	Coronary angioplasty			OFFSIDES
345	Culture positive			OFFSIDES
346	Cutaneous Candidiasis			OFFSIDES
347	Cutaneous hypersensitivity			SIDER
348	Cyst			OFFSIDES
349	Cytomegalovirus chorioretinitis			OFFSIDES
350	Death of relative			OFFSIDES
351	Debridement			OFFSIDES
352	Decreased Libido			OFFSIDES
353	Dehydration			OFFSIDES
354	Delusional disorder, unspecified type			OFFSIDES
355	Dementia		1390620	CTD
356	Demyelination			OFFSIDES
357	Denture wearer			OFFSIDES
358	Dependence			OFFSIDES
359	Depression suicidal			OFFSIDES
360	Depressive disorder		View details 1734612 2008540 2181694 2491140 2708559 3756264 5049831 5578096 6028741 6759061 7294224 7507712 8131152 8444823 8743774 12082591 12416604 17089931 19439248	CTD
361	Dermatitis			SIDER
362	Device malfunction			OFFSIDES
363	Device occlusion			OFFSIDES
364	Diabetes			OFFSIDES
365	Diabetic Foot			OFFSIDES
366	Diabetic Nephropathy			OFFSIDES
367	Diabetic Retinopathy			OFFSIDES
368	Diarrhea			OFFSIDES
369	Diastolic dysfunction			OFFSIDES
370	Disturbance in sexual arousal			SIDER
371	Diverticulum			OFFSIDES
372	Double Outlet Right Ventricle			OFFSIDES
373	Drowsiness			OFFSIDES SIDER
374	Drug Tolerance			OFFSIDES
375	Drug abuser			OFFSIDES
376	Drug addict			OFFSIDES
377	Drug administered at inappropriate site			OFFSIDES
378	Drug dose omission			OFFSIDES
379	Drug exposure before pregnancy			OFFSIDES
380	Drug level fluctuating			OFFSIDES
381	Drug screen positive			OFFSIDES
382	Drug toxicity			OFFSIDES
383	Drug withdrawal headache			OFFSIDES
384	Drug withdrawal syndrome			SIDER
385	Duodenal Obstruction			OFFSIDES
386	Duodenal Ulcer			OFFSIDES
387	Duodenitis			OFFSIDES
388	Dysmenorrhea			OFFSIDES
389	Dyspareunia			OFFSIDES
390	Dysphemia			OFFSIDES
391	Dysthymic Disorder			OFFSIDES
392	Dystonia			OFFSIDES
393	Ear congestion			OFFSIDES
394	Ear discharge			OFFSIDES
395	Ear discomfort	Canada Vigilance: 1		Canada Vigilance OFFSIDES
396	Early satiety			OFFSIDES
397	Economic problem			OFFSIDES
398	Eczema			OFFSIDES
399	Edema		375687 6759061	CTD
400	Electrocardiogram QRS complex			SIDER
401	Electrocardiogram ST-T change			OFFSIDES
402	Electromechanical dissociation			OFFSIDES
403	Emergency Care			OFFSIDES
404	Emotional distress			OFFSIDES
405	Encephalomalacia			OFFSIDES
406	Endodontic procedure			OFFSIDES
407	Endometrial disorder			OFFSIDES
408	Endometriosis			OFFSIDES
409	Enterococcal infection			OFFSIDES
410	Enuresis		5026029	CTD
411	Eosinophilia			SIDER
412	Epicondylitis			OFFSIDES
413	Epidural lipomatosis			OFFSIDES
414	Epigastric distress			SIDER
415	Erectile dysfunction			SIDER
416	Erosive gastritis			OFFSIDES
417	Erythema Infectiosum			OFFSIDES
418	Escherichia urinary tract infection			OFFSIDES
419	Excessive eye blinking			OFFSIDES
420	Eye inflammation			OFFSIDES
421	Facial Neuralgia			OFFSIDES
422	Fanconi Syndrome			OFFSIDES
423	Fat necrosis			OFFSIDES
424	Fatty Liver			OFFSIDES
425	Feeding tube complication			OFFSIDES
426	Feeling of body temperature change			OFFSIDES
427	Feelings of worthlessness			OFFSIDES
428	Fibromyalgia			OFFSIDES
429	Fistula repair			OFFSIDES
430	Flank Pain			OFFSIDES
431	Flat affect			OFFSIDES
432	Flatulence			OFFSIDES
433	Food craving			OFFSIDES
434	Foreign body trauma			OFFSIDES
435	Formication			OFFSIDES
436	Freezing phenomenon			OFFSIDES
437	Gastrectomy			OFFSIDES
438	Gastric Bypass			OFFSIDES
439	Gastric infection			OFFSIDES
440	Gastroduodenitis			OFFSIDES
441	Gastrointestinal sounds abnormal			OFFSIDES
442	Gastrointestinal tract adenoma			OFFSIDES
443	Gastrooesophageal reflux prophylaxis			OFFSIDES
444	General physical health deterioration			OFFSIDES
445	Genital swelling			OFFSIDES
446	Gestational Diabetes			OFFSIDES
447	Gingivitis			SIDER
448	Glasgow coma scale			OFFSIDES
449	Globulinuria			OFFSIDES
450	Glomerulonephritis			OFFSIDES
451	Glossitis	Canada Vigilance: 1		Canada Vigilance
452	Gout			OFFSIDES
453	Grip strength			OFFSIDES
454	Hallucinations		6707238	CTD
455	Hay fever			OFFSIDES
456	Head discomfort	Canada Vigilance: 1		Canada Vigilance
457	Hearing aid user			OFFSIDES
458	Heart Block		6028741	CTD
459	Heart sounds abnormal			OFFSIDES
460	Hemiparesis			OFFSIDES
461	Hepatic necrosis			SIDER
462	Hepatitis C			OFFSIDES
463	Hepatitis		8848811	CTD SIDER
464	Hepatosplenic T-cell lymphoma			OFFSIDES
465	Hepatotoxicity	Canada Vigilance: 1		Canada Vigilance
466	Hernia obstructive			OFFSIDES
467	Hidradenitis			OFFSIDES
468	High frequency ablation			OFFSIDES
469	Hoarseness		507219 7369424	CTD
470	Homicide			OFFSIDES
471	Huntington Disease		17686041	CTD
472	Hydronephrosis			OFFSIDES
473	Hyperacusis	Canada Vigilance: 2		Canada Vigilance
474	Hyperpigmentation			OFFSIDES
475	Hypertensive heart disease			OFFSIDES
476	Hypoaesthesia facial			OFFSIDES
477	Hypomania			SIDER
478	Hypophagia			OFFSIDES
479	Hypotension, Orthostatic		View details 2708559 2768204 3323263 6277997 7507712 7804386 8444823 11673748 12082591	CTD
480	Hypoxia			OFFSIDES
481	Hysterectomy			OFFSIDES
482	Hysteroscopy			OFFSIDES
483	Idiosyncratic drug reaction			OFFSIDES
484	Iliac artery occlusion			OFFSIDES
485	Impaired work ability			OFFSIDES
486	Implant site reaction			OFFSIDES
487	Incontinence			OFFSIDES
488	Increased bronchial secretion			OFFSIDES
489	Increased upper airway secretion			OFFSIDES
490	Infarction, Middle Cerebral Artery		18174477	CTD
491	Infectious Mononucleosis			OFFSIDES
492	Infusion site pain			OFFSIDES
493	Inhibitory drug interaction			OFFSIDES
494	Initial insomnia			OFFSIDES
495	Injection site dermatitis			OFFSIDES
496	Injection site erythema			OFFSIDES
497	Injection site inflammation			OFFSIDES
498	Injection site irritation			OFFSIDES
499	Injection site papule			OFFSIDES
500	Injection site pruritus			OFFSIDES
501	Injection site stinging			OFFSIDES
502	Injection site urticaria			OFFSIDES
503	Intention tremor			OFFSIDES
504	Intentional misuse			OFFSIDES
505	Intentional self-injury			OFFSIDES
506	Intermittent Claudication			OFFSIDES
507	Intervertebral Disc Degeneration			OFFSIDES
508	Intervertebral disc disorder			OFFSIDES
509	Intestinal Obstruction			OFFSIDES
510	Intracranial Hypotension			OFFSIDES
511	Joint injury			OFFSIDES
512	Joint stiffness			OFFSIDES
513	Labile hypertension			OFFSIDES
514	Laceration			OFFSIDES
515	Laryngospasm			OFFSIDES
516	Left atrial dilatation			OFFSIDES
517	Leukocytosis	Canada Vigilance: 1		Canada Vigilance
518	Leukopenia			SIDER
519	Life expectancy shortened			OFFSIDES
520	Limb discomfort			OFFSIDES
521	Limb injury			OFFSIDES
522	Livedo Reticularis			OFFSIDES
523	Liver Failure, Acute		7884180	CTD
524	Long QT Syndrome		1928479 10875054	CTD
525	Loose tooth			OFFSIDES
526	Lumbar radiculopathy			OFFSIDES
527	Lung consolidation			OFFSIDES
528	Lung hyperinflation			OFFSIDES
529	Lymphadenitis			SIDER
530	Lymphocyte count decreased			OFFSIDES
531	Macrocytosis			OFFSIDES
532	Malignant tumour excision			OFFSIDES
533	Mastoiditis			OFFSIDES
534	Meningioma			OFFSIDES
535	Menorrhagia	Canada Vigilance: 1		Canada Vigilance
536	Menstrual discomfort			OFFSIDES
537	Mental disorders		16856516	CTD
538	Mental impairment			OFFSIDES
539	Mesenteric vascular insufficiency			OFFSIDES
540	Micrographic skin surgery			OFFSIDES
541	Mitral valve sclerosis			OFFSIDES
542	Monoclonal immunoglobulin present			OFFSIDES
543	Monocyte count decreased	Canada Vigilance: 1		Canada Vigilance
544	Mononeuritis			OFFSIDES
545	Monoplegia			OFFSIDES
546	Mood Disorders		507219	CTD
547	Motor retardation			OFFSIDES
548	Multiple Myeloma			OFFSIDES
549	Multiple Sclerosis			OFFSIDES
550	Multiple drug overdose			OFFSIDES
551	Multiple drug overdose intentional			OFFSIDES
552	Multiple sclerosis relapse			OFFSIDES
553	Muscle Fatigue			OFFSIDES
554	Muscle Weakness			OFFSIDES
555	Muscle strain			OFFSIDES
556	Musculoskeletal Pain			OFFSIDES
557	Musculoskeletal discomfort	Canada Vigilance: 1		Canada Vigilance OFFSIDES
558	Musculoskeletal stiffness			OFFSIDES
559	Mydriasis			SIDER
560	Myeloma recurrence			OFFSIDES
561	Myocardial Infarction		429744	CTD SIDER
562	Myoclonus		1390620 2181694 3827519	CTD
563	Nasal sinus drainage			OFFSIDES
564	Nephrectomy			OFFSIDES
565	Nephrogenic Fibrosing Dermopathy			OFFSIDES
566	Nephrolithiasis			OFFSIDES
567	Nephrotic Syndrome			OFFSIDES
568	Nerve Block			OFFSIDES
569	Nerve Root Compression			OFFSIDES
570	Nervous tension			OFFSIDES
571	Neuropsychological test abnormal			OFFSIDES
572	Neutropenic sepsis			OFFSIDES
573	Nicotine Dependence			OFFSIDES
574	Nocturia			OFFSIDES SIDER
575	Numbness			SIDER
576	Obsessive-Compulsive Disorder		17089931	CTD
577	Obstruction			OFFSIDES
578	Onychalgia			OFFSIDES
579	Open wound			OFFSIDES
580	Opiates positive			OFFSIDES
581	Optic Disc Edema			OFFSIDES
582	Optic Neuropathy			OFFSIDES
583	Oral Cavity Fistula			OFFSIDES
584	Oral mucosal exfoliation			OFFSIDES
585	Oroantral Fistula			OFFSIDES
586	Oropharyngeal blistering			OFFSIDES
587	Oropharyngeal cancer stage unspecified			OFFSIDES
588	Oropharyngeal discomfort			SIDER
589	Oropharyngeal pain			OFFSIDES SIDER
590	Orthopnea			OFFSIDES
591	Orthostatic intolerance		3756264	CTD
592	Osteolysis			OFFSIDES
593	Osteomyelitis drainage			OFFSIDES
594	Osteomyelitis			OFFSIDES
595	Osteopenia			OFFSIDES
596	Osteosclerosis			OFFSIDES
597	Overweight			OFFSIDES
598	Oxygen supplementation			OFFSIDES
599	PCO2 decreased			OFFSIDES
600	Pallor			OFFSIDES
601	Pancreatitis			OFFSIDES
602	Pancytopenia	Canada Vigilance: 1		Canada Vigilance SIDER
603	Panic Disorder		2731426 14642980	CTD
604	Panic disorder with agoraphobia			OFFSIDES
605	Papilloma			OFFSIDES
606	Paranasal sinus hypersecretion			OFFSIDES
607	Paresthesia of limbs			SIDER
608	Parotid swelling			SIDER
609	Periodontal destruction			OFFSIDES
610	Periodontitis			OFFSIDES
611	Peripheral Nervous System Diseases		9283933	CTD
612	Personality Change			OFFSIDES
613	Personality change due to a general medical condition			OFFSIDES
614	Petechiae	Canada Vigilance: 2		Canada Vigilance SIDER
615	Pharyngolaryngeal Pain			OFFSIDES
616	Phlebosclerosis			OFFSIDES
617	Phonophobia			OFFSIDES
618	Photophobia	Canada Vigilance: 1		Canada Vigilance
619	Physical disability			OFFSIDES
620	Piloerection			OFFSIDES
621	Pituitary enlargement			OFFSIDES
622	Plasmacytosis			OFFSIDES
623	Pneumobilia			OFFSIDES
624	Pneumocephalus			OFFSIDES
625	Polyneuropathy			OFFSIDES
626	Polysubstance abuse			OFFSIDES
627	Polysubstance dependence			OFFSIDES
628	Poor quality sleep			OFFSIDES
629	Post procedural complication			OFFSIDES
630	Post procedural nausea			OFFSIDES
631	Post procedural pain			OFFSIDES
632	Post-traumatic pain			OFFSIDES
633	Postoperative adhesion			OFFSIDES
634	Postoperative renal failure			OFFSIDES
635	Pre-Eclampsia			OFFSIDES
636	Prenatal Exposure Delayed Effects		5049831	CTD
637	Primary sequestrum			OFFSIDES
638	Procedural site reaction			OFFSIDES
639	Proctitis			OFFSIDES
640	Progressive multiple sclerosis			OFFSIDES
641	Prostatism			OFFSIDES
642	Protein total increased			OFFSIDES
643	Psoriasis			OFFSIDES
644	Psychiatric symptom			OFFSIDES
645	Psychomotor skills impaired			OFFSIDES
646	Psychotic Disorders		6707238	CTD
647	Pulmonary Hypertension			OFFSIDES
648	Pulmonary Infarction			OFFSIDES
649	Pulmonary Valve Stenosis			OFFSIDES
650	Pulmonary congestion			OFFSIDES
651	Pulmonary radiation injury			OFFSIDES
652	Pulmonary thrombosis			OFFSIDES
653	Purpura	Canada Vigilance: 1		Canada Vigilance SIDER
654	Pyelonephritis			OFFSIDES
655	Quality of life decreased			OFFSIDES
656	Radicular pain			OFFSIDES
657	Rectal cramps			OFFSIDES
658	Rectal tenesmus			OFFSIDES
659	Reduced facial expression	Canada Vigilance: 2		Canada Vigilance
660	Reflux gastritis			OFFSIDES
661	Reflux laryngitis			OFFSIDES
662	Regurgitation			OFFSIDES
663	Renal Colic			OFFSIDES
664	Renal mass			OFFSIDES
665	Renal tubular necrosis			OFFSIDES
666	Respiratory Failure			OFFSIDES
667	Respiratory tract congestion			OFFSIDES
668	Retrocollis			OFFSIDES
669	Rhinalgia			OFFSIDES
670	Rhinitis			OFFSIDES
671	Rhinorrhea			OFFSIDES
672	Right ventricular systolic pressure increased			OFFSIDES
673	Scan lymph nodes			OFFSIDES
674	Schizoaffective Disorder			OFFSIDES
675	Seizures		18499931 20306168	CTD
676	Self Mutilation			OFFSIDES
677	Sensation of blood flow	Canada Vigilance: 1		Canada Vigilance
678	Sequestrectomy			OFFSIDES
679	Shock			SIDER
680	Shoulder Pain			OFFSIDES
681	Shunt malfunction			OFFSIDES
682	Sinus headache			OFFSIDES
683	Sinusitis	Canada Vigilance: 1		Canada Vigilance OFFSIDES
684	Skeletal injury			OFFSIDES
685	Skin hypertrophy			OFFSIDES
686	Skin lesion			OFFSIDES
687	Skin necrosis			OFFSIDES
688	Sleep Initiation and Maintenance Disorders		6759061	CTD
689	Sleep Wake Disorders		8204191	CTD
690	Snoring			OFFSIDES
691	Somatoform Disorder			OFFSIDES
692	Sopor			OFFSIDES
693	Spinal Fractures		20306168	CTD
694	Spinal column stenosis			OFFSIDES
695	Spinal fusion surgery			OFFSIDES
696	Spinal haemangioma			OFFSIDES
697	Spondylolisthesis			OFFSIDES
698	Spondylolysis			OFFSIDES
699	Spondylosis			OFFSIDES
700	Squamous cell carcinoma of skin			OFFSIDES
701	Staphylococcal abscess			OFFSIDES
702	Stasis dermatitis			OFFSIDES
703	Stem cell transplant			OFFSIDES
704	Stomatitis			SIDER
705	Stress at work			OFFSIDES
706	Stress			OFFSIDES
707	Submandibular mass			OFFSIDES
708	Substance Withdrawal Syndrome		6707238	CTD
709	Sudden death			OFFSIDES
710	Sweating			SIDER
711	Synovial Cyst			OFFSIDES
712	Synovial fluid analysis abnormal			OFFSIDES
713	Takotsubo Cardiomyopathy		18568805	CTD
714	Talipes			OFFSIDES
715	Tardive Dyskinesia			OFFSIDES
716	Tarsal Tunnel Syndrome			OFFSIDES
717	Taste Disorders			SIDER
718	Taste peculiar			SIDER
719	Tendinitis			OFFSIDES
720	Tension			SIDER
721	Therapy non-responder			OFFSIDES
722	Thrombocytopenia			SIDER
723	Tobacco Use Disorder		20469625 21658141	CTD
724	Tonsillitis			OFFSIDES
725	Tooth Erosion			OFFSIDES
726	Tooth Extraction			OFFSIDES
727	Tooth Infection			OFFSIDES
728	Tooth Loss			OFFSIDES
729	Tooth repair			OFFSIDES
730	Tracheobronchitis viral			OFFSIDES
731	Troponin increased			OFFSIDES
732	Unemployment			OFFSIDES
733	Unevaluable event			OFFSIDES
734	Upper airway obstruction			OFFSIDES
735	Urethral stricture			OFFSIDES
736	Urinary Retention	Canada Vigilance: 1	5049831	CTD SIDER Canada Vigilance
737	Urinary tract infection pseudomonal			OFFSIDES
738	Urination Disorders		19721108	CTD
739	Urine flow decreased			OFFSIDES
740	Urticaria	Canada Vigilance: 1		Canada Vigilance SIDER
741	Vagus Nerve Disorder	Canada Vigilance: 1		Canada Vigilance
742	Vascular calcification			OFFSIDES
743	Vascular purpura			SIDER
744	Vascular rupture			OFFSIDES
745	Vasculitic rash			OFFSIDES
746	Venoocclusive disease			OFFSIDES
747	Venous Insufficiency			OFFSIDES
748	Venous occlusion			OFFSIDES
749	Vertigo	Canada Vigilance: 5		Canada Vigilance
750	Vestibulocochlear Nerve Diseases		5026029	CTD
751	Viral pharyngitis			OFFSIDES
752	Vision Disorders		4566251	CTD
753	Visual disturbance			OFFSIDES
754	Vitamin A Deficiency			OFFSIDES
755	Vitamin B 12 Deficiency			OFFSIDES
756	Vocal cord polypectomy			OFFSIDES
757	Vulvovaginal dryness			OFFSIDES
758	Water Pollution			OFFSIDES
759	Weight Gain		12082591 19721108	CTD OFFSIDES
760	Wound dehiscence			OFFSIDES
761	Wrong technique in product usage process	Canada Vigilance: 1		Canada Vigilance
762	Xerostomia		View details 375687 3756264 6759061 7369424 9699704 10607968 11673748 12098632 19721108	CTD
763	Yawning			OFFSIDES
764	bone marrow fibrosis			OFFSIDES
765	furuncle			OFFSIDES
766	jaundice			SIDER
767	keratoacanthoma			OFFSIDES
768	kyphosis			OFFSIDES
769	muscle injury			OFFSIDES
770	prostatitis			OFFSIDES

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