MetaADEDB 2.0 @ LMMD
Oxymetazoline
(WYWIFABBXFUGLM-UHFFFAOYSA-N)
Structure
SMILES
Cc1cc(c(c(c1CC1=NCCN1)C)O)C(C)(C)C
Type(s)
Approved; Investigational
ATC code(s)
R01AA05; R01AB07; S01GA04
Molecular Formula:
C16H24N2O
Molecular Weight:
260.375
Log P:
2.6151
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
2
TPSA:
44.62
CAS Number(s):
1491-59-4
Synonym(s)
1.
Oxymetazoline
2.
Oxymetazoline Hydrochloride
3.
Hydrochloride, Oxymetazoline
External Link(s)
MeSHD010109
PubChem Compound4636
BindingDB30712
50027075
ChEBI7862
CHEMBLCHEMBL762
DrugBankDB00935
DrugCentral2032
IUPHAR/BPS Guide to PHARMACOLOGY124
KEGGcpd:C07363
dr:D08322
Therapeutic Target DatabaseD09EBS
ZINC57435
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 115US FAERS
2Nasal discomfortFAERS: 69OFFSIDES
US FAERS
3Drug DependenceFAERS: 61US FAERS
4Burning sensationFAERS: 44US FAERS
5Incorrect drug administration durationFAERS: 38OFFSIDES
US FAERS
6Accidental exposure to productFAERS: 30US FAERS
7AnosmiaFAERS: 28OFFSIDES
US FAERS
8DependenceFAERS: 28OFFSIDES
US FAERS
9Rebound effectFAERS: 26OFFSIDES
US FAERS
10SneezingFAERS: 25US FAERS
11HeadacheFAERS: 2415367461
16200605		CTD
US FAERS
12EpistaxisFAERS: 23OFFSIDES
US FAERS
13Inappropriate schedule of drug administrationFAERS: 21OFFSIDES
US FAERS
14AgeusiaFAERS: 20OFFSIDES
US FAERS
15OverdoseFAERS: 19US FAERS
16Product quality issueFAERS: 18US FAERS
17Oropharyngeal painFAERS: 17OFFSIDES
US FAERS
18Feeling abnormalFAERS: 16US FAERS
19PainFAERS: 15OFFSIDES
US FAERS
20Wrong technique in drug usage processFAERS: 14US FAERS
21Product container issueFAERS: 13US FAERS
22Throat irritationFAERS: 13US FAERS
23Expired product administeredFAERS: 11US FAERS
24Drug prescribing errorFAERS: 10US FAERS
25RhinalgiaFAERS: 10US FAERS
26Sinus headacheFAERS: 10OFFSIDES
US FAERS
27DizzinessFAERS: 9OFFSIDES
US FAERS
28DiscomfortFAERS: 7US FAERS
29Exposure via direct contactFAERS: 7US FAERS
30Medication ErrorFAERS: 7US FAERS
31Unevaluable eventFAERS: 7US FAERS
32BradycardiaFAERS: 66127404
6888446
8534470		CTD
OFFSIDES
US FAERS
33Drug effect delayedFAERS: 6US FAERS
34Drug ineffective for unapproved indicationFAERS: 6US FAERS
35DysgeusiaFAERS: 6OFFSIDES
US FAERS
36MalaiseFAERS: 6US FAERS
37Product use issueFAERS: 6US FAERS
38Drug administered at inappropriate siteFAERS: 5US FAERS
39Expired drug administeredFAERS: 5US FAERS
40Eye irritationFAERS: 5US FAERS
41Eye painFAERS: 5OFFSIDES
US FAERS
42HypersensitivityFAERS: 5US FAERS
43Intentional drug misuseFAERS: 5OFFSIDES
US FAERS
44NauseaFAERS: 5OFFSIDES
US FAERS
45PruritusFAERS: 5US FAERS
46Cerebral InfarctionFAERS: 4US FAERS
47Drug effect incompleteFAERS: 4US FAERS
48Drug screen positiveFAERS: 4US FAERS
49FatigueFAERS: 4OFFSIDES
US FAERS
50Meningeal disorderFAERS: 4US FAERS
51Nasal mucosal disorderFAERS: 4OFFSIDES
US FAERS
52PalpitationsFAERS: 4US FAERS
53Product label confusionFAERS: 4US FAERS
54Accidental exposureFAERS: 3US FAERS
55Adverse eventFAERS: 3US FAERS
56Angina PectorisFAERS: 3US FAERS
57AsthmaFAERS: 3US FAERS
58Drug exposure during pregnancyFAERS: 3OFFSIDES
US FAERS
59Eosinophilic granulomatosis with polyangiitisFAERS: 3US FAERS
60ErythemaFAERS: 3OFFSIDES
US FAERS
61Feeling jitteryFAERS: 3US FAERS
62HypogeusiaFAERS: 3OFFSIDES
US FAERS
63Incorrect dose administeredFAERS: 3US FAERS
64Product packaging issueFAERS: 3US FAERS
65SinusitisFAERS: 3OFFSIDES
US FAERS
66Upper-airway cough syndromeFAERS: 3US FAERS
67Wrong drug administeredFAERS: 3OFFSIDES
US FAERS
68Abdominal discomfortFAERS: 2OFFSIDES
US FAERS
69Amphetamines positiveFAERS: 2OFFSIDES
US FAERS
70AphoniaFAERS: 2OFFSIDES
US FAERS
71Apparent deathFAERS: 2US FAERS
72Application site painFAERS: 2US FAERS
73BronchospasmFAERS: 2US FAERS
74Circumstance or information capable of leading to medication errorFAERS: 2OFFSIDES
US FAERS
75Drug abuseFAERS: 2US FAERS
76Drug administered to patient of inappropriate ageFAERS: 2US FAERS
77Drug administration errorFAERS: 2US FAERS
78DysphoniaFAERS: 2OFFSIDES
US FAERS
79Feeling ColdFAERS: 2US FAERS
80Granulomatosis with polyangiitisFAERS: 2US FAERS
81HemiparesisFAERS: 2US FAERS
82Nasal inflammationFAERS: 2US FAERS
83Poor quality sleepFAERS: 2OFFSIDES
US FAERS
84Product label issueFAERS: 2US FAERS
85RetchingFAERS: 2US FAERS
86SomnolenceFAERS: 2US FAERS
87Supraventricular tachycardiaFAERS: 2OFFSIDES
US FAERS
88SwellingFAERS: 2US FAERS
89VasculitisFAERS: 2US FAERS
90VomitingFAERS: 2US FAERS
91AbasiaFAERS: 1US FAERS
92Accidental overdoseFAERS: 1US FAERS
93AmnesiaFAERS: 1OFFSIDES
US FAERS
94Anoxic EncephalopathyFAERS: 1US FAERS
95AnxietyFAERS: 1OFFSIDES
US FAERS
96AphagiaFAERS: 1US FAERS
97AphasiaFAERS: 1US FAERS
98AstheniaFAERS: 1OFFSIDES
US FAERS
99Atrial FibrillationFAERS: 1US FAERS
100Blood count abnormalFAERS: 1US FAERS
101Blood glucose increasedFAERS: 1US FAERS
102Blood potassium increasedFAERS: 1US FAERS
103Bone painFAERS: 1US FAERS
104Cerebrovascular accidentFAERS: 1US FAERS
105Chest PainFAERS: 1OFFSIDES
US FAERS
106Chest discomfortFAERS: 1US FAERS
107Choking sensationFAERS: 1OFFSIDES
US FAERS
108ChokingFAERS: 1US FAERS
109CyanopsiaFAERS: 1US FAERS
110DisorientationFAERS: 1US FAERS
111DroolingFAERS: 1US FAERS
112Drug abuserFAERS: 1US FAERS
113Drug screen false positiveFAERS: 1US FAERS
114DysuriaFAERS: 1US FAERS
115Economic problemFAERS: 1US FAERS
116Electroencephalogram abnormalFAERS: 1US FAERS
117Emotional distressFAERS: 1OFFSIDES
US FAERS
118Epigastric discomfortFAERS: 1US FAERS
119Erectile dysfunctionFAERS: 1US FAERS
120Euphoric moodFAERS: 1US FAERS
121Exposure during breast feedingFAERS: 1US FAERS
122Exposure via ingestionFAERS: 1US FAERS
123Facial ParesisFAERS: 1US FAERS
124Food AllergyFAERS: 1US FAERS
125FormicationFAERS: 1OFFSIDES
US FAERS
126HyperreflexiaFAERS: 1US FAERS
127HypophagiaFAERS: 1OFFSIDES
US FAERS
128HypotensionFAERS: 16888446CTD
US FAERS
129Incorrect product storageFAERS: 1US FAERS
130Incorrect route of drug administrationFAERS: 1US FAERS
131Increased upper airway secretionFAERS: 1US FAERS
132InflammationFAERS: 1US FAERS
133Initial insomniaFAERS: 1US FAERS
134Instillation site painFAERS: 1US FAERS
135Liquid product physical issueFAERS: 1US FAERS
136Mental status changesFAERS: 1US FAERS
137Multiple allergiesFAERS: 1US FAERS
138MydriasisFAERS: 1US FAERS
139Nasal PolypsFAERS: 1US FAERS
140NasopharyngitisFAERS: 1US FAERS
141NervousnessFAERS: 1US FAERS
142Paranasal sinus discomfortFAERS: 1US FAERS
143Pharmaceutical product complaintFAERS: 1US FAERS
144PregnancyFAERS: 1US FAERS
145PresyncopeFAERS: 1US FAERS
146Procedural complicationFAERS: 1US FAERS
147Product closure issueFAERS: 1US FAERS
148Product closure removal difficultFAERS: 1US FAERS
149Product packaging confusionFAERS: 1US FAERS
150Product substitution issueFAERS: 1US FAERS
151Respiratory DepressionFAERS: 1US FAERS
152Respiratory tract congestionFAERS: 1US FAERS
153RhinitisFAERS: 1OFFSIDES
US FAERS
154ScabFAERS: 1US FAERS
155Sinus operationFAERS: 1OFFSIDES
US FAERS
156Skin texture abnormalFAERS: 1US FAERS
157StomatitisFAERS: 1US FAERS
158StressFAERS: 1OFFSIDES
US FAERS
159StridorFAERS: 1US FAERS
160Therapeutic product ineffectiveFAERS: 1US FAERS
161Therapeutic product ineffective for unapproved indicationFAERS: 1US FAERS
162Therapeutic response changedFAERS: 1US FAERS
163Therapeutic response unexpectedFAERS: 1US FAERS
164ToothacheFAERS: 1US FAERS
165UrticariaFAERS: 1US FAERS
166Abdominal PainOFFSIDES
167AbscessOFFSIDES
168Acute sinusitisOFFSIDES
169AlveoloplastyOFFSIDES
170AngerOFFSIDES
171AnhidrosisOFFSIDES
172Ankle reconstructionOFFSIDES
173AnorexiaOFFSIDES
174Anti-platelet antibody positiveOFFSIDES
175Anticoagulation drug level below therapeuticOFFSIDES
176AppendectomyOFFSIDES
177ArteriosclerosisOFFSIDES
178ArthritisOFFSIDES
179AtherosclerosisOFFSIDES
180Bacterial Infections12669766CTD
181Basal cell carcinomaOFFSIDES
182Blood GlucoseOFFSIDES
183Blood iron decreasedOFFSIDES
184Blood pressure fluctuationOFFSIDES
185Blood triglycerides increasedOFFSIDES
186Blurred visionOFFSIDES
187Bone density decreasedOFFSIDES
188Bone fragmentationOFFSIDES
189Bone lesionOFFSIDES
190Bone scan abnormalOFFSIDES
191Bone trimmingOFFSIDES
192Brain ConcussionOFFSIDES
193Breast cancer recurrentOFFSIDES
194BronchitisOFFSIDES
195BruxismOFFSIDES
196Chronic Obstructive Airway DiseaseOFFSIDES
197Common Cold20030735CTD
198ConfabulationOFFSIDES
199Congenital heart diseaseOFFSIDES
200Congenital tricuspid valve incompetenceOFFSIDES
201Conjunctival depositOFFSIDES
202CyanosisOFFSIDES
203CystOFFSIDES
204DeafnessOFFSIDES
205DebridementOFFSIDES
206DehydrationOFFSIDES
207DemyelinationOFFSIDES
208Dental abscessOFFSIDES
209Dental cariesOFFSIDES
210Depressed Level of ConsciousnessOFFSIDES
211Device related infectionOFFSIDES
212DiabetesOFFSIDES
213Diabetic RetinopathyOFFSIDES
214DiarrheaOFFSIDES
215Diverticular herniaOFFSIDES
216DiverticulumOFFSIDES
217Drug Overdose3340705CTD
218Drug addictOFFSIDES
219Drug withdrawal headacheOFFSIDES
220DyscheziaOFFSIDES
221DyspepsiaOFFSIDES
222Ear congestionOFFSIDES
223EczemaOFFSIDES
224Endometrial disorderOFFSIDES
225EndophthalmitisOFFSIDES
226Enterococcal infectionOFFSIDES
227Ethmoid sinus surgeryOFFSIDES
228Eye InfectionOFFSIDES
229Fatty LiverOFFSIDES
230FlatulenceOFFSIDES
231GastroduodenitisOFFSIDES
232Genital HerpesOFFSIDES
233Hepatitis BOFFSIDES
234Hepatitis COFFSIDES
235HydronephrosisOFFSIDES
236Impaired driving abilityOFFSIDES
237InfectionOFFSIDES
238Infusion site mobility decreasedOFFSIDES
239Injection site dermatitisOFFSIDES
240Intervertebral Disc DegenerationOFFSIDES
241Jaw lesion excisionOFFSIDES
242Joint sprainOFFSIDES
243Kidney FailureOFFSIDES
244Left Ventricular HypertrophyOFFSIDES
245LethargyOFFSIDES
246LymphedemaOFFSIDES
247Malignant melanoma in situOFFSIDES
248Malignant neoplasm progressionOFFSIDES
249Maxillofacial operationOFFSIDES
250Megakaryocytes increasedOFFSIDES
251Mental impairmentOFFSIDES
252Metastatic NeoplasmOFFSIDES
253Mouth cystOFFSIDES
254Mucosal atrophyOFFSIDES
255Muscle necrosisOFFSIDES
256MyopiaOFFSIDES
257Nerve Root CompressionOFFSIDES
258NoduleOFFSIDES
259Open woundOFFSIDES
260Optic Neuropathy, Ischemic9933016CTD
261Oroantral FistulaOFFSIDES
262OsteomyelitisOFFSIDES
263Patellofemoral Pain SyndromeOFFSIDES
264Pericardial effusionOFFSIDES
265PericarditisOFFSIDES
266Physical assaultOFFSIDES
267PneumothoraxOFFSIDES
268Primary sequestrumOFFSIDES
269Productive CoughOFFSIDES
270Protein total decreasedOFFSIDES
271Psychomotor Agitation3340705CTD
272Psychoses, Substance-Induced8293377CTD
273PurulenceOFFSIDES
274Purulent dischargeOFFSIDES
275Rectal fissureOFFSIDES
276Renal cystOFFSIDES
277RhinorrheaOFFSIDES
278Seizures6104728CTD
279SequestrectomyOFFSIDES
280Sinus Arrest, Cardiac8534470CTD
281Sinus antrostomyOFFSIDES
282Sinus polypOFFSIDES
283Skeletal injuryOFFSIDES
284Skin IndurationOFFSIDES
285Skin lacerationOFFSIDES
286Skin neoplasm excisionOFFSIDES
287Sleep Initiation and Maintenance Disorders3340705CTD
288Spinal column stenosisOFFSIDES
289SpondylolisthesisOFFSIDES
290Subarachnoid Hemorrhage12791938CTD
291Subcutaneous AbscessOFFSIDES
292Substance Withdrawal Syndrome3597333CTD
293Syncope19775485CTD
294TalipesOFFSIDES
295Therapy non-responderOFFSIDES
296Tooth ExtractionOFFSIDES
297Troponin increasedOFFSIDES
298Vasospasm, Intracranial16200605CTD
299Vertebrobasilar InsufficiencyOFFSIDES
300Vision Disorders9933016CTD
301Vitreous DetachmentOFFSIDES
302Walking aid userOFFSIDES
303Wound dehiscenceOFFSIDES
304effusionOFFSIDES
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