MetaADEDB: Drug

MetaADEDB 2.0 @ LMMD

Acetazolamide

(BZKPWHYZMXOIDC-UHFFFAOYSA-N)

Structure

SMILES: CC(=O)Nc1nnc(s1)S(=O)(=O)N
Type(s): Approved; Vet_approved
ATC code(s): G01AE10; S01EC01
Molecular Formula:: C4H6N4O3S2
Molecular Weight:: 222.245
Log P:: 0.9980
Hydrogen Bond Acceptor:: 8
Hydrogen Bond Donor:: 2
TPSA:: 151.66
CAS Number(s):: 59-66-5

Synonym(s)

Acetazolamide

Acetadiazol

Acetazolam

Acetazolamide Sodium, (Sterile)

Acetazolamide, Monosodium Salt

Ak-Zol

Apo-Acetazolamide

Diacarb

Diamox

10.

Diuramide

11.

Défiltran

12.

Edemox

13.

Glauconox

14.

Glaupax

15.

Huma-Zolamide

16.

Ak Zol

17.

AkZol

18.

Apo Acetazolamide

19.

ApoAcetazolamide

20.

Huma Zolamide

21.

HumaZolamide

External Link(s)

MeSH	D000086
PubChem Compound	1986
BindingDB	10880
ChEBI	27690
CHEMBL	CHEMBL20
DrugBank	DB00819
DrugCentral	56
IUPHAR/BPS Guide to PHARMACOLOGY	6792
KEGG	cpd:C06805 dr:D00218
Therapeutic Target Database	D0E1SW
ZINC	3813042

Adverse Drug Event(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Headache	FAERS: 27	View details 15863216 18452541 19393521 19438913	CTD SIDER US FAERS
2	Drug ineffective	FAERS: 19 Canada Vigilance: 2		Canada Vigilance US FAERS
3	Metabolic acidosis	FAERS: 18 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
4	Nausea	FAERS: 15 Canada Vigilance: 3	2712085	CTD OFFSIDES SIDER Canada Vigilance US FAERS
5	Dizziness	FAERS: 14 Canada Vigilance: 3		Canada Vigilance SIDER US FAERS
6	Angle Closure Glaucoma	FAERS: 13		OFFSIDES US FAERS
7	Vomiting	FAERS: 13 Canada Vigilance: 1	12649241	CTD SIDER Canada Vigilance US FAERS
8	Dysgeusia	FAERS: 9	19689182	CTD OFFSIDES SIDER US FAERS
9	Fatigue	FAERS: 8 Canada Vigilance: 1	View details 2712085 3769383 8434677 11985388	CTD SIDER Canada Vigilance US FAERS
10	Product substitution issue	FAERS: 8		US FAERS
11	Acidosis	FAERS: 7	View details 848601 2016806 2109942 3769383 6065848 10221197 16772765 17536990	CTD OFFSIDES US FAERS
12	Somnolence	FAERS: 7 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
13	Asthenia	FAERS: 6 Canada Vigilance: 2		Canada Vigilance OFFSIDES SIDER US FAERS
14	Dehydration	FAERS: 6		OFFSIDES US FAERS
15	Hypersensitivity	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
16	Product use issue	FAERS: 6		US FAERS
17	Abdominal discomfort	FAERS: 5 Canada Vigilance: 1		Canada Vigilance US FAERS
18	Ataxia	FAERS: 5	10091644 17575025	CTD OFFSIDES SIDER US FAERS
19	Malaise	FAERS: 5		SIDER US FAERS
20	Nephrolithiasis	FAERS: 5	View details 2016806 4191454 5353483 15455790	CTD US FAERS
21	Urticaria	FAERS: 5	11792017	CTD SIDER US FAERS
22	Weight decreased	FAERS: 5 Canada Vigilance: 1		Canada Vigilance US FAERS
23	Anxiety	FAERS: 4		US FAERS
24	Arthralgia	FAERS: 4		US FAERS
25	Cholelithiasis	FAERS: 4		US FAERS
26	Disorientation	FAERS: 4		US FAERS
27	Hypotension	FAERS: 4 Canada Vigilance: 2		Canada Vigilance US FAERS
28	Product quality issue	FAERS: 4		US FAERS
29	Toxicity to various agents	FAERS: 4		US FAERS
30	Tremor	FAERS: 4 Canada Vigilance: 1	8041383	CTD Canada Vigilance US FAERS
31	Visual Impairment	FAERS: 4		US FAERS
32	Abdominal Pain	FAERS: 3	8434677	CTD US FAERS
33	Acute kidney injury	FAERS: 3	View details 634875 1124417 2655449 8447311 9154665 9780431	CTD US FAERS
34	Adverse event	FAERS: 3		US FAERS
35	Burning sensation	FAERS: 3		US FAERS
36	Cerebral Infarction	FAERS: 3 Canada Vigilance: 1		Canada Vigilance US FAERS
37	Chest Pain	FAERS: 3		US FAERS
38	Drug prescribing error	FAERS: 3		US FAERS
39	Eye pain	FAERS: 3		OFFSIDES US FAERS
40	Familial Periodic Paralysis	FAERS: 3		US FAERS
41	Feeling abnormal	FAERS: 3		SIDER US FAERS
42	Inappropriate schedule of drug administration	FAERS: 3		US FAERS
43	Lethargy	FAERS: 3 Canada Vigilance: 2	3769383	CTD Canada Vigilance US FAERS
44	Memory impairment	FAERS: 3		US FAERS
45	Respiratory Failure	FAERS: 3		OFFSIDES US FAERS
46	Respiratory distress	FAERS: 3		US FAERS
47	Acute respiratory failure	FAERS: 2		OFFSIDES US FAERS
48	Amnesia	FAERS: 2		US FAERS
49	Back Pain	FAERS: 2		US FAERS
50	Blood creatinine increased	FAERS: 2		US FAERS
51	Blood glucose increased	FAERS: 2		US FAERS
52	Blood pressure fluctuation	FAERS: 2		US FAERS
53	Blood urea increased	FAERS: 2		OFFSIDES US FAERS
54	Brain Death	FAERS: 2	17536990	CTD US FAERS
55	Cerebrovascular accident	FAERS: 2		US FAERS
56	Deafness	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
57	Delirium	FAERS: 2	848601	CTD US FAERS
58	Depressed Level of Consciousness	FAERS: 2		US FAERS
59	Drug exposure during pregnancy	FAERS: 2		OFFSIDES US FAERS
60	Dysarthria	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
61	Dysuria	FAERS: 2		US FAERS
62	Hypoxia	FAERS: 2	6816846	CTD OFFSIDES US FAERS
63	Intentional product use issue	FAERS: 2		US FAERS
64	Medication Error	FAERS: 2		US FAERS
65	Mental status changes	FAERS: 2		US FAERS
66	Muscle hypertrophy	FAERS: 2		US FAERS
67	Myalgia	FAERS: 2		US FAERS
68	Nystagmus	FAERS: 2		OFFSIDES US FAERS
69	Pain	FAERS: 2 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
70	Palpitations	FAERS: 2		US FAERS
71	Pharmaceutical product complaint	FAERS: 2		US FAERS
72	Product use in unapproved indication	FAERS: 2		US FAERS
73	Pruritus	FAERS: 2 Canada Vigilance: 2		Canada Vigilance US FAERS
74	Renal Colic	FAERS: 2	5071712	CTD US FAERS
75	Renal tubular acidosis	FAERS: 2		OFFSIDES US FAERS
76	Retching	FAERS: 2		US FAERS
77	Screaming	FAERS: 2		US FAERS
78	Stevens-Johnson Syndrome	FAERS: 2	25811541	CTD OFFSIDES SIDER US FAERS
79	Therapeutic response unexpected	FAERS: 2		US FAERS
80	Tinnitus	FAERS: 2 Canada Vigilance: 3		Canada Vigilance OFFSIDES SIDER US FAERS
81	Visual brightness	FAERS: 2		US FAERS
82	Acquired Immunodeficiency Syndrome	FAERS: 1		US FAERS
83	Acute myopia	FAERS: 1		US FAERS
84	Ageusia	FAERS: 1		US FAERS
85	Agitation	FAERS: 1		SIDER US FAERS
86	Alopecia	FAERS: 1		US FAERS
87	Ammonia increased	FAERS: 1		US FAERS
88	Anaphylactic shock	FAERS: 1		SIDER US FAERS
89	Anger	FAERS: 1		US FAERS
90	Anion Gap	FAERS: 1		US FAERS
91	Anosmia	FAERS: 1		US FAERS
92	Anuria	FAERS: 1	634875	CTD OFFSIDES US FAERS
93	Apparent death	FAERS: 1		US FAERS
94	Autophobia	FAERS: 1		US FAERS
95	Blindness	FAERS: 1		US FAERS
96	Blood creatine phosphokinase increased	FAERS: 1		OFFSIDES US FAERS
97	Blood electrolytes abnormal	FAERS: 1		US FAERS
98	Blood potassium decreased	FAERS: 1 Canada Vigilance: 1		Canada Vigilance OFFSIDES US FAERS
99	Blood pressure immeasurable	FAERS: 1		US FAERS
100	Blood sodium decreased	FAERS: 1		US FAERS
101	Blood urine present	FAERS: 1		US FAERS
102	Body height below normal	FAERS: 1		US FAERS
103	Bone pain	FAERS: 1		US FAERS
104	Bradycardia	FAERS: 1		OFFSIDES US FAERS
105	Calcinosis	FAERS: 1		US FAERS
106	Cerebellar Ataxia	FAERS: 1	10221197 11096749	CTD US FAERS
107	Chest discomfort	FAERS: 1		US FAERS
108	Chills	FAERS: 1 Canada Vigilance: 2		Canada Vigilance US FAERS
109	Chromaturia	FAERS: 1		US FAERS
110	Coma scale abnormal	FAERS: 1		US FAERS
111	Completed Suicide	FAERS: 1		US FAERS
112	Constipation	FAERS: 1		US FAERS
113	Crying	FAERS: 1		US FAERS
114	Cyanosis	FAERS: 1		US FAERS
115	Deep Vein Thrombosis	FAERS: 1		US FAERS
116	Dementia	FAERS: 1		US FAERS
117	Diabetes mellitus inadequate control	FAERS: 1		US FAERS
118	Disease Progression	FAERS: 1		US FAERS
119	Disease recurrence	FAERS: 1		US FAERS
120	Dissociation	FAERS: 1		US FAERS
121	Documented hypersensitivity to administered product	FAERS: 1		US FAERS
122	Drug administration error	FAERS: 1		US FAERS
123	Drug dose omission	FAERS: 1		US FAERS
124	Drug effect incomplete	FAERS: 1		US FAERS
125	Drug ineffective for unapproved indication	FAERS: 1		US FAERS
126	Drug-disease interaction	FAERS: 1		US FAERS
127	Dyspepsia	FAERS: 1		SIDER US FAERS
128	Dysphonia	FAERS: 1		US FAERS
129	Ear congestion	FAERS: 1		US FAERS
130	Economic problem	FAERS: 1		OFFSIDES US FAERS
131	Epigastric discomfort	FAERS: 1		US FAERS
132	Expired product administered	FAERS: 1		US FAERS
133	Flatulence	FAERS: 1		US FAERS
134	Food Allergy	FAERS: 1		US FAERS
135	Food aversion	FAERS: 1		US FAERS
136	Gastric ulcer	FAERS: 1		US FAERS
137	Gastrointestinal motility disorder	FAERS: 1		US FAERS
138	General physical health deterioration	FAERS: 1		OFFSIDES US FAERS
139	Growth retardation	FAERS: 1		SIDER US FAERS
140	Head discomfort	FAERS: 1		US FAERS
141	Hemiparesis	FAERS: 1		US FAERS
142	Hepatic Encephalopathy	FAERS: 1		US FAERS
143	Hypercapnia	FAERS: 1		OFFSIDES US FAERS
144	Hypersomnia	FAERS: 1		US FAERS
145	Hypokinesia	FAERS: 1		OFFSIDES US FAERS
146	Hypophagia	FAERS: 1		US FAERS
147	Illogical thinking	FAERS: 1		US FAERS
148	Incorrect dose administered	FAERS: 1		US FAERS
149	Increased tendency to bruise	FAERS: 1		US FAERS
150	Increased upper airway secretion	FAERS: 1		US FAERS
151	Inhibitory drug interaction	FAERS: 1		US FAERS
152	Joint swelling	FAERS: 1		US FAERS
153	Live Birth	FAERS: 1		US FAERS
154	Lymphadenopathy	FAERS: 1		US FAERS
155	Monoplegia	FAERS: 1		US FAERS
156	Musculoskeletal stiffness	FAERS: 1		US FAERS
157	Myopia	FAERS: 1		SIDER US FAERS
158	Neck Pain	FAERS: 1		US FAERS
159	Necrosis	FAERS: 1		US FAERS
160	Neutrophil count decreased	FAERS: 1		OFFSIDES US FAERS
161	Ocular discomfort	FAERS: 1		US FAERS
162	Oral pain	FAERS: 1		US FAERS
163	Oropharyngeal pain	FAERS: 1		US FAERS
164	Pallor	FAERS: 1		OFFSIDES US FAERS
165	Pancreatitis	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
166	Paranoia	FAERS: 1		US FAERS
167	Peripheral swelling	FAERS: 1		US FAERS
168	Personality Change	FAERS: 1		US FAERS
169	Pneumonia	FAERS: 1		US FAERS
170	Polydipsia	FAERS: 1		SIDER US FAERS
171	Polyuria	FAERS: 1		OFFSIDES SIDER US FAERS
172	Post procedural complication	FAERS: 1		US FAERS
173	Pregnancy	FAERS: 1		US FAERS
174	Prescribed overdose	FAERS: 1		OFFSIDES US FAERS
175	Product physical issue	FAERS: 1		US FAERS
176	Pulmonary Embolism	FAERS: 1		US FAERS
177	Renal tubular necrosis	FAERS: 1		OFFSIDES US FAERS
178	Respiratory Depression	FAERS: 1		US FAERS
179	Rheumatoid Arthritis	FAERS: 1		US FAERS
180	Shock	FAERS: 1 Canada Vigilance: 1		Canada Vigilance SIDER US FAERS
181	Snoring	FAERS: 1		US FAERS
182	Strabismus	FAERS: 1		US FAERS
183	Syncope	FAERS: 1		US FAERS
184	Therapy non-responder	FAERS: 1		US FAERS
185	Unevaluable event	FAERS: 1		US FAERS
186	Urinary tract infection	FAERS: 1		US FAERS
187	Vertigo	FAERS: 1		US FAERS
188	Visual disturbance	FAERS: 1		OFFSIDES US FAERS
189	Vitreous Detachment	FAERS: 1		US FAERS
190	Vitreous floaters	FAERS: 1		US FAERS
191	Vitritis	FAERS: 1		US FAERS
192	Abasia			OFFSIDES
193	Abdominal sepsis			OFFSIDES
194	Abnormalities, Drug-Induced		16298872	CTD
195	Accidental death			OFFSIDES
196	Acid reflux			OFFSIDES
197	Acute bronchitis			OFFSIDES
198	Acute tonsillitis			OFFSIDES
199	Adenitis			OFFSIDES
200	Agranulocytosis			SIDER
201	Alkalosis		6410668 6816846	CTD
202	Altered state of consciousness			OFFSIDES
203	Altitude Sickness		1978045 2712085 6349608	CTD
204	Alveolitis			OFFSIDES
205	Amphetamines			OFFSIDES
206	Anaphylactoid Reaction			SIDER
207	Anorexia		6391074	CTD
208	Anticonvulsant drug level increased			OFFSIDES
209	Antiphospholipid Syndrome			OFFSIDES
210	Apallic syndrome			OFFSIDES
211	Apnea		2712085	CTD OFFSIDES
212	Arthropathy			OFFSIDES
213	Asthma			OFFSIDES
214	Astigmatism			OFFSIDES
215	Atherosclerosis			OFFSIDES
216	Atrial Flutter			OFFSIDES
217	Avascular necrosis			OFFSIDES
218	Bedridden			OFFSIDES
219	Blood beta-D-glucan increased			OFFSIDES
220	Blood calcitonin increased			OFFSIDES
221	Blood chloride increased			OFFSIDES
222	Blood glucose abnormal			OFFSIDES
223	Blood glucose decreased			OFFSIDES
224	Blood magnesium increased			OFFSIDES
225	Blood parathyroid hormone increased			OFFSIDES
226	Blood sodium			OFFSIDES
227	Blurred vision			OFFSIDES
228	Body Temperature			OFFSIDES
229	Brain Edema		10742073 17536990	CTD
230	Bronchial secretion retention			OFFSIDES
231	Bronchopneumonia			OFFSIDES
232	Cardiac Arrest	Canada Vigilance: 2		Canada Vigilance
233	Cardiac Tamponade			OFFSIDES
234	Cataract operation			OFFSIDES
235	Cataract			OFFSIDES
236	Cerebral Hemorrhage		1622512	CTD
237	Cerebral atrophy			OFFSIDES
238	Chemotherapeutic drug level increased			OFFSIDES
239	Choking sensation			OFFSIDES
240	Choroidal Detachment			OFFSIDES
241	Chronic Obstructive Airway Disease			OFFSIDES
242	Chronic respiratory failure			OFFSIDES
243	Circumstance or information capable of leading to medication error			OFFSIDES
244	Cleft Palate			OFFSIDES
245	Cognition Disorders		19689182	CTD
246	Confabulation			OFFSIDES
247	Confusion		3769383 10221197	CTD
248	Congenital heart disease			OFFSIDES
249	Congenital tricuspid valve incompetence			OFFSIDES
250	Conjunctival deposit			OFFSIDES
251	Corneal Ulcer			OFFSIDES
252	Corneal exfoliation			OFFSIDES
253	Corneal graft rejection			OFFSIDES
254	Corneal touch			OFFSIDES
255	Craniocerebral Trauma		17536990	CTD
256	Cyst			OFFSIDES
257	Deafness Neurosensory			OFFSIDES
258	Demyelination			OFFSIDES
259	Depression suicidal			OFFSIDES
260	Diabetes Insipidus			OFFSIDES
261	Diabetic Nephropathy			OFFSIDES
262	Diarrhea		8434677	CTD OFFSIDES
263	Diplopia	Canada Vigilance: 2		Canada Vigilance
264	Discomfort			SIDER
265	Disseminated Intravascular Coagulation			OFFSIDES
266	Diverticular perforation			OFFSIDES
267	Diverticulum		6542938	CTD
268	Drowsiness			OFFSIDES SIDER
269	Drug Eruptions		11792017	CTD
270	Drug abuser			OFFSIDES
271	Drug toxicity			OFFSIDES
272	Drug withdrawal headache			OFFSIDES
273	Dry skin			OFFSIDES
274	Duodenal Ulcer			OFFSIDES
275	Duodenitis			OFFSIDES
276	Dysthymic Disorder			OFFSIDES
277	Dystonia		15455790	CTD
278	Electrolyte imbalance	Canada Vigilance: 1		Canada Vigilance SIDER
279	Embolic cerebral infarction			OFFSIDES
280	Emotional distress			OFFSIDES
281	Endophthalmitis			OFFSIDES
282	Epidermolysis			OFFSIDES
283	Epilepsy		1246508 10474731 11934510	CTD OFFSIDES
284	Epistaxis			OFFSIDES
285	Erectile dysfunction		3566023	CTD
286	Erythema Multiforme			SIDER
287	Escherichia sepsis			OFFSIDES
288	Exophthalmos			OFFSIDES
289	Exposure to toxic agent			OFFSIDES
290	Eye Injuries		3812474	CTD
291	Eye inflammation			OFFSIDES
292	Facial Neuralgia			OFFSIDES
293	Fatty Liver			OFFSIDES
294	Feeding and Eating Disorders		2712085	CTD
295	Fibromyalgia	Canada Vigilance: 1		Canada Vigilance
296	Flail Chest			OFFSIDES
297	Fluid overload			OFFSIDES
298	Flushing			SIDER
299	Formication			OFFSIDES
300	Gambling			OFFSIDES
301	Gangrene			OFFSIDES
302	Gastroduodenitis			OFFSIDES
303	Gerstmann Syndrome		10692744	CTD
304	Glaucoma		View details 1124417 4706085 5395427 9307648	CTD OFFSIDES
305	Glycosuria			SIDER
306	Goiter			OFFSIDES
307	Hamartoma			OFFSIDES
308	Headache Disorders, Primary		14581696	CTD
309	Hematuria		6658117	CTD
310	Hepatic Insufficiency			SIDER
311	Hepatic necrosis			SIDER
312	Hepatosplenomegaly			OFFSIDES
313	Hydrocephalus		1622512 10207925	CTD OFFSIDES
314	Hyperalgesia		15743922	CTD
315	Hyperammonemia		17575025	CTD
316	Hypercalciuria		1622512	CTD
317	Hyperemia		15296063	CTD
318	Hyperplasia		6520738 6542938	CTD
319	Hypertensive heart disease			OFFSIDES
320	Hypertrophy		721694	CTD
321	Hyperventilation		2109942	CTD OFFSIDES
322	Hypocapnia		17536990	CTD
323	Hypokalemia		7031501	CTD
324	Hypokalemic periodic paralysis		7031501 14766795	CTD
325	Hysterectomy			OFFSIDES
326	Idiopathic intracranial hypertension with papilledema		18070060	CTD
327	Immune reconstitution syndrome			OFFSIDES
328	Immunosuppressant drug level			OFFSIDES
329	Incontinence			OFFSIDES
330	Infant, Premature, Diseases		1622512	CTD
331	Infectious Mononucleosis			OFFSIDES
332	Inflammation		6520738	CTD
333	Injection site pain			SIDER
334	Intention tremor			OFFSIDES
335	Intracranial Hypertension		2320196 12649241 15184329	CTD
336	Intraocular inflammation			OFFSIDES
337	Iridocyclitis			OFFSIDES
338	Iritis			OFFSIDES
339	Kidney Calculi		View details 1235390 1622512 2122276 3433023 8170551 10474731	CTD
340	Kidney Failure			OFFSIDES
341	Left Ventricular Hypertrophy			OFFSIDES
342	Legionella serology positive			OFFSIDES
343	Leukoencephalopathy			OFFSIDES
344	Leukopenia			SIDER
345	Macrocytosis			OFFSIDES
346	Malignant neoplasm progression			OFFSIDES
347	Memory Disorders		11985388	CTD
348	Meningioma			OFFSIDES
349	Migraine Disorders		15613201 19438913	CTD
350	Mitral valve sclerosis			OFFSIDES
351	Monoparesis			OFFSIDES
352	Multiple Sclerosis			OFFSIDES
353	Multiple drug overdose			OFFSIDES
354	Muscle Weakness		12322805	CTD
355	Muscle tightness			OFFSIDES
356	Musculoskeletal chest pain			OFFSIDES
357	Myocardial Ischemia		9529283	CTD
358	Myoclonic Epilepsy			OFFSIDES
359	Myopia transient			SIDER
360	Myotonia Congenita		11985388	CTD
361	Myotonia		8170551	CTD
362	Myotonic Disorders		835937	CTD
363	Nephrocalcinosis		View details 1622512 5353483 7950830 10207925 11096312	CTD
364	Neurologic Manifestations		1462998 15772552	CTD
365	Numbness			SIDER
366	Ocular Hypertension		32733	CTD
367	Onycholysis			OFFSIDES
368	Ophthalmic fluid drainage			OFFSIDES
369	Optic Disc Edema			OFFSIDES
370	Osteomalacia			SIDER
371	Pain, Postoperative		14508327	CTD
372	Pancytopenia	Canada Vigilance: 2	5395427	CTD Canada Vigilance
373	Papilledema		View details 7760885 12471353 12649241 18452541	CTD
374	Paracentesis			OFFSIDES
375	Paresthesia		View details 1978045 6349608 6391074 10915127 11985388	CTD
376	Parophthalmia			OFFSIDES
377	Partner stress			OFFSIDES
378	Pericardial effusion			OFFSIDES
379	Pericarditis			OFFSIDES
380	Peritonsillar Abscess			OFFSIDES
381	Pre-Eclampsia			OFFSIDES
382	Prolonged expiration			OFFSIDES
383	Prostate examination abnormal			OFFSIDES
384	Pseudotumor Cerebri		View details 6844972 7760885 8447311 10369621 11824142 15818308 15863216 19018859	CTD
385	Psychomotor Agitation		576479	CTD
386	Pulmonary Hypertension			OFFSIDES
387	Pulmonary arterial hypertension			OFFSIDES
388	Pulmonary thrombosis			OFFSIDES
389	Quadriplegia		835937	CTD
390	Rales			OFFSIDES
391	Rash erythematous	Canada Vigilance: 1		Canada Vigilance
392	Reaction gastrointestinal			SIDER
393	Respiratory Insufficiency		2712085	CTD
394	Retinal Artery Occlusion		6112544	CTD OFFSIDES
395	Retinogram abnormal			OFFSIDES
396	Rosacea		8251374	CTD
397	Sagittal Sinus Thrombosis		6844972	CTD
398	Scotoma			OFFSIDES
399	Seizures		3607518 7554689 11879338	CTD
400	Septic Shock			OFFSIDES
401	Serratia sepsis			OFFSIDES
402	Shunt malfunction			OFFSIDES
403	Skeletal injury			OFFSIDES
404	Sleep Apnea, Central		9696283	CTD
405	Sleep Wake Disorders		2712085 8434677	CTD
406	Status Epilepticus			OFFSIDES
407	Talipes			OFFSIDES
408	Taste Disorders		1978045 6391074	CTD
409	Tenosynovitis			OFFSIDES
410	Therapeutic response unexpected with drug substitution			OFFSIDES
411	Thirst			SIDER
412	Thrombocytopenia			SIDER
413	Thrombocytopenic purpura			SIDER
414	Tingling of extremity			SIDER
415	Toxic Epidermal Necrolysis			SIDER
416	Trabeculectomy			OFFSIDES
417	Traumatic fracture			OFFSIDES
418	Troponin increased			OFFSIDES
419	Ureteral Calculi		6542938	CTD
420	Ureteral obstruction		634875 5071712	CTD
421	Urinary Calculi		4706085	CTD
422	Urinary Incontinence		3769383	CTD
423	Urine output increased			SIDER
424	Urolithiasis		713211 5071712 6520738	CTD
425	Urologic Diseases		6520738	CTD
426	Vertebrobasilar Insufficiency		9367331	CTD
427	Vitamin A Deficiency			OFFSIDES

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