MetaADEDB 2.0 @ LMMD
acetaminophen, dextropropoxyphene, drug combination
(OZKVMNTVUAGULY-VGHSCWAPSA-N)
Structure
SMILES
CC(=O)Nc1ccc(cc1)O.CCC(=O)O[C@](c1ccccc1)([C@@H](CN(C)C)C)Cc1ccccc1.Cl
Molecular Formula:
C30H39ClN2O4
Molecular Weight:
527.095
Log P:
6.5011
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
3
TPSA:
78.87
CAS Number(s):
39400-85-6
Synonym(s)
1.
acetaminophen, dextropropoxyphene, drug combination
2.
Co-proxamol
3.
Coproxamol
4.
Darvocet-N
5.
Di-antalvic
6.
Diantalvic
7.
Distalgesic
8.
acetaminophen - dextropropoxyphene
9.
acetaminophen - propoxyphene
10.
acetaminophen - propoxyphene hydrochloride
11.
acetaminophen, propoxyphene hydrochloride drug combination
12.
acetaminophen-propoxyphene hydrochloride
External Link(s)
MeSHC011800
PubChem Compound123857
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 50US FAERS
2BradycardiaFAERS: 1OFFSIDES
US FAERS
3DisabilityFAERS: 1US FAERS
4DizzinessFAERS: 1US FAERS
5MalaiseFAERS: 1US FAERS
6PresyncopeFAERS: 1US FAERS
7Ventricular arrhythmiaFAERS: 1US FAERS
8AcidosisOFFSIDES
9AdenocarcinomaOFFSIDES
10AgraphiaOFFSIDES
11Alanine Aminotransferase IncreasedOFFSIDES
12Altered state of consciousnessOFFSIDES
13Ammonia increasedOFFSIDES
14AmnesiaOFFSIDES
15Anal FistulaOFFSIDES
16AngerOFFSIDES
17AnisocoriaOFFSIDES
18Anticonvulsant drug level above therapeuticOFFSIDES
19Anticonvulsant drug level increasedOFFSIDES
20Antidepressant drug clearance decreasedOFFSIDES
21Antiviral drug level above therapeuticOFFSIDES
22Aspiration PneumoniaOFFSIDES
23AsterixisOFFSIDES
24Ataxia7831181CTD
25AtopyOFFSIDES
26AuraOFFSIDES
27Autoimmune thyroiditisOFFSIDES
28Basal cell carcinomaOFFSIDES
29BicytopeniaOFFSIDES
30Bilirubin conjugated increasedOFFSIDES
31Blood alkaline phosphatase increasedOFFSIDES
32Blood count abnormalOFFSIDES
33Blood creatine phosphokinase increasedOFFSIDES
34Blood creatinine increasedOFFSIDES
35Blood glucose false positiveOFFSIDES
36Blood potassium increasedOFFSIDES
37Blood sodiumOFFSIDES
38Blood urea increasedOFFSIDES
39Body TemperatureOFFSIDES
40BronchiectasisOFFSIDES
41BronchopneumoniaOFFSIDES
42Cell DeathOFFSIDES
43Cerebellar Diseases7831181CTD
44Cerebral ArteriosclerosisOFFSIDES
45CholangiolitisOFFSIDES
46ConfabulationOFFSIDES
47Creatinine renal clearance decreasedOFFSIDES
48Creutzfeldt-Jakob diseaseOFFSIDES
49Culture positiveOFFSIDES
50Cytolytic hepatitisOFFSIDES
51DehydrationOFFSIDES
52Delayed deliveryOFFSIDES
53Depressed Level of ConsciousnessOFFSIDES
54Depressed moodOFFSIDES
55DiplopiaOFFSIDES
56DiverticulumOFFSIDES
57DrowsinessOFFSIDES
58Drug abuserOFFSIDES
59Duodenal ulcer perforationOFFSIDES
60EczemaOFFSIDES
61EnteritisOFFSIDES
62Enterococcal infectionOFFSIDES
63Enterovesical FistulaOFFSIDES
64EpiduritisOFFSIDES
65EpilepsyOFFSIDES
66Escherichia infectionOFFSIDES
67Escherichia urinary tract infectionOFFSIDES
68Fatty LiverOFFSIDES
69Febrile bone marrow aplasiaOFFSIDES
70Gamma-Glutamyltransferase IncreasedOFFSIDES
71Gastric StenosisOFFSIDES
72General physical health deteriorationOFFSIDES
73GranulocytosisOFFSIDES
74Hematuria1247776
1252799		CTD
75HepatitisOFFSIDES
76Hypoventilation6476315CTD
77Injection site dermatitisOFFSIDES
78Injection site infectionOFFSIDES
79Injury asphyxiationOFFSIDES
80Intervertebral disc disorderOFFSIDES
81JC virus infectionOFFSIDES
82Kidney FailureOFFSIDES
83Lymphocytic infiltrationOFFSIDES
84Mechanical complication of implantOFFSIDES
85Metabolic acidosisOFFSIDES
86Metastatic NeoplasmOFFSIDES
87Metastatic Renal Cell CarcinomaOFFSIDES
88Metastatic bronchial carcinomaOFFSIDES
89Multiple drug overdoseOFFSIDES
90Multiple drug overdose intentionalOFFSIDES
91Muscle necrosisOFFSIDES
92Myeloid maturation arrestOFFSIDES
93Neutropenic sepsisOFFSIDES
94Ocular ToxicityOFFSIDES
95OliguriaOFFSIDES
96Optic Disc EdemaOFFSIDES
97OverdoseOFFSIDES
98Pancreatic enlargementOFFSIDES
99ParakeratosisOFFSIDES
100Personality ChangeOFFSIDES
101Pneumococcal sepsisOFFSIDES
102Porphyromonas infectionOFFSIDES
103Post procedural painOFFSIDES
104Prostatic AdenomaOFFSIDES
105PsoriasisOFFSIDES
106Pulmonary arterial hypertensionOFFSIDES
107RalesOFFSIDES
108Reperfusion arrhythmiaOFFSIDES
109Retinal vascular thrombosisOFFSIDES
110Rheumatoid VasculitisOFFSIDES
111Septic ShockOFFSIDES
112Single umbilical arteryOFFSIDES
113Sinusitis aspergillusOFFSIDES
114Speech Disorders7831181CTD
115SpondylosisOFFSIDES
116Sputum culture positiveOFFSIDES
117Stevens-Johnson SyndromeOFFSIDES
118Stress at workOFFSIDES
119SubileusOFFSIDES
120TonsillitisOFFSIDES
121Tooth ResorptionOFFSIDES
122Transaminases increasedOFFSIDES
123Tremor7831181CTD
124Urine ketone body presentOFFSIDES
125Veillonella infectionOFFSIDES
126Ventricular hypokinesiaOFFSIDES
127Wound InfectionOFFSIDES
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