Glyxambi
(POMOOZUJAXCEKG-QPVQWCQSSA-N)
Structure
- SMILES
- CO[C@H]1O[C@@H](c2ccc(c(c2)Cc2ccc(cc2)O[C@@H]2COCC2)Cl)[C@@H]([C@H]([C@@H]1O)O)O.CC#CCn1c(nc2c1c(=O)n(Cc1nc(C)c3c(n1)cccc3)c(=O)n2C)N1CCC[C@H](C1)N
- Molecular Formula:
- C48H55ClN8O9
- Molecular Weight:
- 923.452
- Log P:
- 4.1377
- Hydrogen Bond Acceptor:
- 17
- Hydrogen Bond Donor:
- 4
- TPSA:
- 214.47
- CAS Number(s):
- N/A
Synonym(s)
1.
Glyxambi
External Link(s)
| PubChem Compound | 85364159 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Diabetic Ketoacidosis | FAERS: 37 | US FAERS | |
| 2 | Weight decreased | FAERS: 21 | US FAERS | |
| 3 | Blood glucose increased | FAERS: 20 | US FAERS | |
| 4 | Dehydration | FAERS: 18 | US FAERS | |
| 5 | Nausea | FAERS: 17 | US FAERS | |
| 6 | Urinary tract infection | FAERS: 15 | US FAERS | |
| 7 | Pancreatitis | FAERS: 14 | US FAERS | |
| 8 | Dizziness | FAERS: 13 | US FAERS | |
| 9 | Pruritus | FAERS: 10 | US FAERS | |
| 10 | Vomiting | FAERS: 10 | US FAERS | |
| 11 | Headache | FAERS: 9 | US FAERS | |
| 12 | Drug ineffective | FAERS: 8 | US FAERS | |
| 13 | Abdominal Pain | FAERS: 7 | US FAERS | |
| 14 | Constipation | FAERS: 7 | US FAERS | |
| 15 | Myalgia | FAERS: 7 | US FAERS | |
| 16 | Vulvovaginal mycotic infection | FAERS: 7 | US FAERS | |
| 17 | Ketoacidosis | FAERS: 6 | US FAERS | |
| 18 | Unevaluable event | FAERS: 6 | US FAERS | |
| 19 | Alopecia | FAERS: 5 | US FAERS | |
| 20 | Blood glucose abnormal | FAERS: 5 | US FAERS | |
| 21 | Cerebrovascular accident | FAERS: 5 | US FAERS | |
| 22 | Fatigue | FAERS: 5 | US FAERS | |
| 23 | Genital infection fungal | FAERS: 5 | US FAERS | |
| 24 | Malaise | FAERS: 5 | US FAERS | |
| 25 | Myocardial Infarction | FAERS: 5 | US FAERS | |
| 26 | Urticaria | FAERS: 5 | US FAERS | |
| 27 | Amnesia | FAERS: 4 | US FAERS | |
| 28 | Asthenia | FAERS: 4 | US FAERS | |
| 29 | Dysuria | FAERS: 4 | US FAERS | |
| 30 | Euglycaemic diabetic ketoacidosis | FAERS: 4 | US FAERS | |
| 31 | Pain | FAERS: 4 | US FAERS | |
| 32 | Pneumonia | FAERS: 4 | US FAERS | |
| 33 | Acidosis | FAERS: 3 | US FAERS | |
| 34 | Blood creatinine increased | FAERS: 3 | US FAERS | |
| 35 | Blood glucose decreased | FAERS: 3 | US FAERS | |
| 36 | Blood glucose fluctuation | FAERS: 3 | US FAERS | |
| 37 | Blood urine present | FAERS: 3 | US FAERS | |
| 38 | Diabetes mellitus inadequate control | FAERS: 3 | US FAERS | |
| 39 | Feeling abnormal | FAERS: 3 | US FAERS | |
| 40 | Hypersensitivity | FAERS: 3 | US FAERS | |
| 41 | Influenza | FAERS: 3 | US FAERS | |
| 42 | Medication Error | FAERS: 3 | US FAERS | |
| 43 | Metabolic acidosis | FAERS: 3 | US FAERS | |
| 44 | Musculoskeletal Pain | FAERS: 3 | US FAERS | |
| 45 | No adverse event | FAERS: 3 | US FAERS | |
| 46 | Oropharyngeal pain | FAERS: 3 | US FAERS | |
| 47 | Palpitations | FAERS: 3 | US FAERS | |
| 48 | Somnolence | FAERS: 3 | US FAERS | |
| 49 | Swelling | FAERS: 3 | US FAERS | |
| 50 | Accidental overdose | FAERS: 2 | US FAERS | |
| 51 | Back Pain | FAERS: 2 | US FAERS | |
| 52 | Balanoposthitis | FAERS: 2 | US FAERS | |
| 53 | Bowel movement irregularity | FAERS: 2 | US FAERS | |
| 54 | Burning sensation | FAERS: 2 | US FAERS | |
| 55 | Chills | FAERS: 2 | US FAERS | |
| 56 | Cholelithiasis | FAERS: 2 | US FAERS | |
| 57 | Dysphonia | FAERS: 2 | US FAERS | |
| 58 | Epistaxis | FAERS: 2 | US FAERS | |
| 59 | Erectile dysfunction | FAERS: 2 | US FAERS | |
| 60 | Food craving | FAERS: 2 | US FAERS | |
| 61 | Genital infection | FAERS: 2 | US FAERS | |
| 62 | Hypophagia | FAERS: 2 | US FAERS | |
| 63 | Intestinal Obstruction | FAERS: 2 | US FAERS | |
| 64 | Lip swelling | FAERS: 2 | US FAERS | |
| 65 | Nasopharyngitis | FAERS: 2 | US FAERS | |
| 66 | Nephrolithiasis | FAERS: 2 | US FAERS | |
| 67 | Therapeutic response unexpected | FAERS: 2 | US FAERS | |
| 68 | Thirst | FAERS: 2 | US FAERS | |
| 69 | Urinary tract infection fungal | FAERS: 2 | US FAERS | |
| 70 | Acute kidney injury | FAERS: 1 | US FAERS | |
| 71 | Acute psychosis | FAERS: 1 | US FAERS | |
| 72 | Adverse event | FAERS: 1 | US FAERS | |
| 73 | Alanine Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 74 | Angioedema | FAERS: 1 | US FAERS | |
| 75 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 76 | Atrial Fibrillation | FAERS: 1 | US FAERS | |
| 77 | Blindness | FAERS: 1 | US FAERS | |
| 78 | Blood Glucose | FAERS: 1 | US FAERS | |
| 79 | Blood creatinine abnormal | FAERS: 1 | US FAERS | |
| 80 | Blood insulin decreased | FAERS: 1 | US FAERS | |
| 81 | Blood ketone body increased | FAERS: 1 | US FAERS | |
| 82 | Blood potassium increased | FAERS: 1 | US FAERS | |
| 83 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 84 | Blood thyroid stimulating hormone increased | FAERS: 1 | US FAERS | |
| 85 | Blood triglycerides increased | FAERS: 1 | US FAERS | |
| 86 | Blood urea increased | FAERS: 1 | US FAERS | |
| 87 | Bone abscess | FAERS: 1 | US FAERS | |
| 88 | Bronchitis | FAERS: 1 | US FAERS | |
| 89 | Cachexia | FAERS: 1 | US FAERS | |
| 90 | Cardiac Death | FAERS: 1 | US FAERS | |
| 91 | Cataract | FAERS: 1 | US FAERS | |
| 92 | Cell marker increased | FAERS: 1 | US FAERS | |
| 93 | Chest Pain | FAERS: 1 | US FAERS | |
| 94 | Cholecystitis | FAERS: 1 | US FAERS | |
| 95 | Colitis | FAERS: 1 | US FAERS | |
| 96 | Cystitis | FAERS: 1 | US FAERS | |
| 97 | Diplopia | FAERS: 1 | US FAERS | |
| 98 | Disorientation | FAERS: 1 | US FAERS | |
| 99 | Diverticulum | FAERS: 1 | US FAERS | |
| 100 | Drug prescribing error | FAERS: 1 | US FAERS | |
| 101 | Dyspepsia | FAERS: 1 | US FAERS | |
| 102 | Eczema | FAERS: 1 | US FAERS | |
| 103 | Electrolyte imbalance | FAERS: 1 | US FAERS | |
| 104 | Eructation | FAERS: 1 | US FAERS | |
| 105 | Erythema | FAERS: 1 | US FAERS | |
| 106 | Eye pain | FAERS: 1 | US FAERS | |
| 107 | Flank Pain | FAERS: 1 | US FAERS | |
| 108 | Flatulence | FAERS: 1 | US FAERS | |
| 109 | Food Poisoning | FAERS: 1 | US FAERS | |
| 110 | Frustration tolerance decreased | FAERS: 1 | US FAERS | |
| 111 | Gastrointestinal infection | FAERS: 1 | US FAERS | |
| 112 | Genital rash | FAERS: 1 | US FAERS | |
| 113 | Gout | FAERS: 1 | US FAERS | |
| 114 | Hypotension | FAERS: 1 | US FAERS | |
| 115 | Incorrect dose administered | FAERS: 1 | US FAERS | |
| 116 | Infection | FAERS: 1 | US FAERS | |
| 117 | Joint injury | FAERS: 1 | US FAERS | |
| 118 | Limb crushing injury | FAERS: 1 | US FAERS | |
| 119 | Limb injury | FAERS: 1 | US FAERS | |
| 120 | Liver Abscess | FAERS: 1 | US FAERS | |
| 121 | Lymphadenopathy | FAERS: 1 | US FAERS | |
| 122 | Measles | FAERS: 1 | US FAERS | |
| 123 | Memory impairment | FAERS: 1 | US FAERS | |
| 124 | Mouth swelling | FAERS: 1 | US FAERS | |
| 125 | Multiple Sclerosis | FAERS: 1 | US FAERS | |
| 126 | Night sweats | FAERS: 1 | US FAERS | |
| 127 | Oral candidiasis | FAERS: 1 | US FAERS | |
| 128 | Paranoia | FAERS: 1 | US FAERS | |
| 129 | Penile Infection | FAERS: 1 | US FAERS | |
| 130 | Peripheral swelling | FAERS: 1 | US FAERS | |
| 131 | Polyuria | FAERS: 1 | US FAERS | |
| 132 | Renal Cell Carcinoma | FAERS: 1 | US FAERS | |
| 133 | Sciatica | FAERS: 1 | US FAERS | |
| 134 | Skin Wrinkling | FAERS: 1 | US FAERS | |
| 135 | Skin tightness | FAERS: 1 | US FAERS | |
| 136 | Syncope | FAERS: 1 | US FAERS | |
| 137 | Tachycardia | FAERS: 1 | US FAERS | |
| 138 | Therapy non-responder | FAERS: 1 | US FAERS | |
| 139 | Tremor | FAERS: 1 | US FAERS | |
| 140 | Urine alcohol test positive | FAERS: 1 | US FAERS | |
| 141 | Vitiligo | FAERS: 1 | US FAERS | |
| 142 | Vulvovaginal pruritus | FAERS: 1 | US FAERS | |
| 143 | Vulvovaginitis | FAERS: 1 | US FAERS |
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