MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Secondary hypothyroidism

(UMLS:C3665349)

UMLS ID:: C3665349
MeSH ID:: D007037

Classification:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.874.482

Synonym(s)

Secondary hypothyroidism

Hypothyrotropic hypothyroidism

Low thyroid gland function due to abnormal pituitary gland

PITUITARY HYPOTHYROIDISM

Pituitary Hypothyroidism

Pituitary hypothyroidism

Pituitary myxedema

TSH - Thyroid stimulating hormone deficiency

TSH deficiency

10.

TSH deficient hypothyroidism

11.

Thyroid stimulating hormone deficiency

12.

Thyrotropin deficiency

13.

hypothyroidism pituitary

14.

hypothyroidism secondary

Associated Drug(s)

	Name	Number of Reports	Data Source
1	rofecoxib	FAERS: 8	OFFSIDES US FAERS
2	Sunitinib	FAERS: 5	US FAERS
3	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 3	US FAERS
4	Amiodarone	FAERS: 1	US FAERS
5	Amiodarone	FAERS: 1	US FAERS
6	Bexarotene	FAERS: 1	US FAERS
7	Cabergoline	FAERS: 1	US FAERS
8	Gefitinib	FAERS: 1	US FAERS
9	Methimazole	FAERS: 1	US FAERS
10	Sertraline	FAERS: 1	US FAERS
11	Sodium iodide I 131	FAERS: 1	US FAERS
12	Vancomycin	FAERS: 1	US FAERS
13	pazopanib	FAERS: 1	US FAERS
14	Beclomethasone		OFFSIDES
15	Gliclazide		OFFSIDES
16	Glipizide		OFFSIDES
17	Methotrimeprazine		OFFSIDES
18	Octreotide		OFFSIDES
19	Sulpiride		OFFSIDES
20	Vardenafil Dihydrochloride		OFFSIDES
21	etizolam		OFFSIDES
22	xylometazoline		OFFSIDES
23	zolmitriptan		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Euthyroid Sick Syndromes	42.9%
2	Goiter	42.9%
3	Hyperthyroidism	42.9%
4	Hyperthyroxinemia	42.9%
5	Thyroiditis	42.9%
6	Primary Hyperthyroidism	42.9%
7	Thyrotoxicosis	31%
8	Thyroid Hormone Resistance Syndrome	31%
9	Hashimoto Disease	25.4%
10	Graves Disease	24.7%
11	Adrenal Gland Diseases	23.1%
12	Gonadal Disorders	23.1%
13	Parathyroid Diseases	23.1%
14	Thyroid Neoplasm	22.2%
15	Thyroid carcinoma	22.2%
16	Autoimmune thyroiditis	20.9%
17	Thyroid Nodule	16%
18	Bone Diseases, Endocrine	15%
19	Endocrine Gland Neoplasms	15%
20	Diabetes Mellitus	14.6%
21	Pituitary Diseases	14.5%
22	Adrenal Cortex Diseases	14.3%
23	Hyperparathyroidism	14.3%
24	Hypogonadism	14.3%
25	Hypoparathyroidism	14.3%
26	Delayed Puberty	14.3%
27	Precocious Puberty	14.3%
28	Hypogonadotropic hypogonadism	14.3%
29	Testotoxicosis	14.3%
30	Adrenal Gland Neoplasms	14%
31	Parathyroid Neoplasms	11.1%
32	Dwarfism	10.9%
33	Cushing Syndrome	10.3%
34	Hyperaldosteronism	10.3%
35	Hyperparathyroidism, Secondary	10.3%
36	Hypoaldosteronism	10.3%
37	Hyperparathyroidism, Primary	10.3%
38	Testicular Diseases	9.5%
39	Ovarian Diseases	9.2%
40	Empty Sella Syndrome	9.1%
41	Hyperpituitarism	9.1%
42	Hypopituitarism	9.1%
43	Hypophysitis	9.1%
44	Hyperglycemic Hyperosmolar Nonketotic Coma	8.5%
45	Adrenocortical carcinoma	8.2%
46	ovarian neoplasm	7.8%
47	Addison Disease	7%
48	Diabetic Angiopathies	7%
49	Primary Adrenal Insufficiency	7%
50	Gestational Diabetes	7%
51	Latent Autoimmune Diabetes in Adults	7%
52	Diabetes Insipidus	6.8%
53	Diabetes Mellitus, Experimental	6.8%
54	Diabetic Neuropathies	6.8%
55	Orchitis	6.8%
56	Diabetic Amyotrophy	6.8%
57	Diabetic Autonomic Neuropathy	6.8%
58	Diabetic Cardiomyopathies	6.8%
59	Testicular Neoplasms	6.8%
60	Ovarian Hyperstimulation Syndrome	6.7%
61	Hyperprolactinemia	6.7%
62	Prolactinoma	6.6%
63	Growth Hormone-Secreting Pituitary Adenoma	6.6%
64	Diabetic Foot	6.6%
65	Nelson Syndrome	6.5%
66	Pituitary Adenoma	5.9%
67	Pituitary Neoplasms	5.9%
68	Hermaphroditism	5.6%
69	Disorders of Sex Development	5.6%
70	Pituitary Apoplexy	5.3%
71	Kallmann Syndrome	5.2%
72	granulosa cell tumor	5.1%
73	Carcinoma, Ovarian Epithelial	5.1%
74	Corpus Luteum Cyst	5.1%
75	Ovarian Cysts	5.1%
76	Gigantism	5.1%
77	Diabetic Nephropathy	5%
78	Acromegaly	5%
79	Anovulation	5%
80	Diabetic Ketoacidosis	5%
81	Oophoritis	5%
82	Multiple Endocrine Neoplasia	4.7%
83	Pancreatic Neoplasm	4.7%
84	Congenital Hypothyroidism	4.5%
85	Klinefelter Syndrome	4.5%
86	Diabetic Retinopathy	4.3%
87	Polycystic Ovary Syndrome	4.1%
88	Cryptorchidism	4.1%
89	Gonadal Dysgenesis	4%
90	Adrenogenital Syndrome	4%
91	Ovotesticular Disorders of Sex Development	4%
92	Leydig Cell Tumor	3.8%
93	Hyperandrogenism	3.6%
94	Multiple Endocrine Neoplasia Type 1	3.3%
95	Carcinoma, Pancreatic Ductal	2.5%
96	insulinoma	2.3%
97	Gastrinoma	2.3%
98	Glucagonoma	2.3%
99	Turner Syndrome	2.3%
100	Carcinoma, Endometrioid	2.3%
101	Renal Osteodystrophy	2%
102	Renal rickets	2%
103	Vipoma	2%
104	Waterhouse-Friderichsen Syndrome	2%
105	Denys-Drash Syndrome	1.2%
106	Adrenoleukodystrophy	1.1%

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