MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hyperparathyroidism, Secondary

(UMLS:C0020503)

Definition:: Abnormally elevated PARATHYROID HORMONE secretion as a response to HYPOCALCEMIA. It is caused by chronic KIDNEY FAILURE or other abnormalities in the controls of bone and mineral metabolism, leading to various BONE DISEASES, such as RENAL OSTEODYSTROPHY.
UMLS ID:: C0020503
MeSH ID:: D006962

Classification:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.642.355.480

Synonym(s)

Hyperparathyroidism, Secondary

HYPERPARATHYROIDISM SECONDARY

Hyperparathyroidism secondary

Hyperparathyroidism, secondary

Secondary Hyperparathyroidism

Secondary hyperparathyroidism

Secondary hyperparathyroidism, NOS

hyperparathyroidism secondary

hyperparathyroidism; secondary

10.

secondary hyperparathyroidism

11.

secondary; hyperparathyroidism

Associated Drug(s)

	Name	Reference(s)	Data Source
1	25-hydroxyvitamin D	23084309	CTD
2	Calcitriol	View details 1453499 2051637 7847357 8261678 8455354 8840326 15354979 16189633 17444814 17984431 21350317	CTD
3	Calcium Compounds	9011580 22373954	CTD
4	Cinacalcet	17472827 18721002 22118402	CTD
5	Furosemide	6637931 15086907	CTD
6	Phenytoin	20683115	CTD
7	Phosphates	15354979 22373954	CTD
8	Vitamin D	11675047 22118402	CTD
9	alfacalcidol	8840326	CTD
10	maxacalcitol	8840326 10027919 16189633	CTD
11	paricalcitol	12618899	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hyperparathyroidism, Primary	46.7%
2	Hypoparathyroidism	31%
3	Adrenal Gland Diseases	18.5%
4	Gonadal Disorders	18.5%
5	Thyroid Diseases	18.5%
6	Parathyroid Neoplasms	16.4%
7	Bone Diseases, Endocrine	12.2%
8	Endocrine Gland Neoplasms	12.2%
9	Diabetes Mellitus	11.9%
10	Pituitary Diseases	11.8%
11	Adrenal Cortex Diseases	10.3%
12	Adrenal Gland Neoplasms	10.3%
13	Euthyroid Sick Syndromes	10.3%
14	Goiter	10.3%
15	Hyperthyroidism	10.3%
16	Hyperthyroxinemia	10.3%
17	Hypogonadism	10.3%
18	Hypothyroidism	10.3%
19	Delayed Puberty	10.3%
20	Precocious Puberty	10.3%
21	Thyroiditis	10.3%
22	Hypogonadotropic hypogonadism	10.3%
23	Testotoxicosis	10.3%
24	Secondary hypothyroidism	10.3%
25	Primary Hyperthyroidism	10.3%
26	Primary Hypothyroidism	10.3%
27	Dwarfism	8.9%
28	Thyroid Neoplasm	8.2%
29	Thyroid carcinoma	8.2%
30	Testicular Diseases	7%
31	Ovarian Diseases	6.7%
32	Empty Sella Syndrome	6.7%
33	Hyperpituitarism	6.7%
34	Hypopituitarism	6.7%
35	Hypophysitis	6.7%
36	Cushing Syndrome	6.7%
37	Hyperaldosteronism	6.7%
38	Hypoaldosteronism	6.7%
39	Thyrotoxicosis	6.7%
40	Thyroid Hormone Resistance Syndrome	6.7%
41	Congenital Hypothyroidism	5.6%
42	ovarian neoplasm	5.5%
43	Graves Disease	5.4%
44	Thyroid Nodule	5.3%
45	Gestational Diabetes	5.1%
46	Latent Autoimmune Diabetes in Adults	5.1%
47	Diabetes Insipidus	5%
48	Diabetes Mellitus, Experimental	5%
49	Hyperglycemic Hyperosmolar Nonketotic Coma	4.9%
50	Hashimoto Disease	4.9%
51	Adrenocortical carcinoma	4.8%
52	Testicular Neoplasms	4.8%
53	Addison Disease	4.5%
54	Diabetic Angiopathies	4.5%
55	Autoimmune thyroiditis	4.5%
56	Primary Adrenal Insufficiency	4.5%
57	Diabetic Neuropathies	4.4%
58	Myxedema	4.4%
59	Orchitis	4.4%
60	Diabetic Amyotrophy	4.4%
61	Diabetic Autonomic Neuropathy	4.4%
62	Diabetic Cardiomyopathies	4.4%
63	Pituitary Adenoma	4.4%
64	Pituitary Neoplasms	4.4%
65	Ovarian Hyperstimulation Syndrome	4.4%
66	Hyperprolactinemia	4.4%
67	Prolactinoma	4.4%
68	Growth Hormone-Secreting Pituitary Adenoma	4.4%
69	Hermaphroditism	4.1%
70	Disorders of Sex Development	4.1%
71	Pituitary Apoplexy	3.9%
72	Diabetic Foot	3.9%
73	Nelson Syndrome	3.9%
74	Multiple Endocrine Neoplasia	3.4%
75	Pancreatic Neoplasm	3.4%
76	Corpus Luteum Cyst	3.3%
77	Ovarian Cysts	3.3%
78	Gigantism	3.3%
79	Diabetic Nephropathy	3.3%
80	Kallmann Syndrome	3.3%
81	Acromegaly	3.3%
82	Anovulation	3.3%
83	Diabetic Ketoacidosis	3.3%
84	Oophoritis	3.3%
85	granulosa cell tumor	3.2%
86	Carcinoma, Ovarian Epithelial	3.2%
87	Klinefelter Syndrome	2.8%
88	Cryptorchidism	2.7%
89	Gonadal Dysgenesis	2.6%
90	Adrenogenital Syndrome	2.6%
91	Ovotesticular Disorders of Sex Development	2.6%
92	Diabetic Retinopathy	2.5%
93	Polycystic Ovary Syndrome	2.4%
94	Leydig Cell Tumor	2.2%
95	Multiple Endocrine Neoplasia Type 1	2.2%
96	Hyperandrogenism	2.1%
97	Carcinoma, Pancreatic Ductal	1.6%
98	Turner Syndrome	1.4%
99	insulinoma	1.4%
100	Gastrinoma	1.4%
101	Glucagonoma	1.4%
102	Carcinoma, Endometrioid	1.4%
103	Waterhouse-Friderichsen Syndrome	1.3%
104	Vipoma	1.2%
105	Adrenoleukodystrophy	0.8%
106	Denys-Drash Syndrome	0.7%

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