Desipramine
(XAEWZDYWZHIUCT-UHFFFAOYSA-N)
Structure
- SMILES
- CNCCCN1c2ccccc2CCc2c1cccc2.Cl
- Molecular Formula:
- C18H23ClN2
- Molecular Weight:
- 302.842
- Log P:
- 4.7907
- Hydrogen Bond Acceptor:
- 1
- Hydrogen Bond Donor:
- 2
- TPSA:
- 15.27
- CAS Number(s):
- 58-28-6
Synonym(s)
1.
Desipramine
2.
Desmethylimipramine
3.
Apo-Desipramine
4.
Demethylimipramine
5.
Desipramine Hydrochloride
6.
Norpramin
7.
Novo-Desipramine
8.
Nu-Desipramine
9.
PMS-Desipramine
10.
Pertofran
11.
Pertofrane
12.
Pertrofran
13.
Petylyl
14.
Ratio-Desipramine
15.
Apo Desipramine
16.
Hydrochloride, Desipramine
17.
Novo Desipramine
18.
Nu Desipramine
19.
PMS Desipramine
20.
Ratio Desipramine
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Drug ineffective | FAERS: 6 | US FAERS | |
| 2 | Anxiety | FAERS: 3 | US FAERS | |
| 3 | Dizziness | FAERS: 3 Canada Vigilance: 8 | Canada Vigilance US FAERS | |
| 4 | Tachycardia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Tremor | FAERS: 3 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 6 | Abdominal discomfort | FAERS: 2 | US FAERS | |
| 7 | Adverse event | FAERS: 2 | US FAERS | |
| 8 | Crying | FAERS: 2 | US FAERS | |
| 9 | Disorientation | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 10 | Palpitations | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 11 | Paranoia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Therapeutic response unexpected with drug substitution | FAERS: 2 | US FAERS | |
| 13 | Throat irritation | FAERS: 2 | US FAERS | |
| 14 | Unevaluable event | FAERS: 2 | US FAERS | |
| 15 | Weight decreased | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | Abdominal Pain | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 17 | Agitation | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 18 | Anger | FAERS: 1 | US FAERS | |
| 19 | Aphasia | FAERS: 1 | US FAERS | |
| 20 | Blood pressure immeasurable | FAERS: 1 | US FAERS | |
| 21 | Burning sensation | FAERS: 1 | US FAERS | |
| 22 | Constipation | FAERS: 1 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 23 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 24 | Diabetic Ketoacidosis | FAERS: 1 | US FAERS | |
| 25 | Drug Dependence | FAERS: 1 | US FAERS | |
| 26 | Drug ineffective for unapproved indication | FAERS: 1 | US FAERS | |
| 27 | Drug level increased | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 28 | Dysgeusia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 29 | Emotional disorder | FAERS: 1 | US FAERS | |
| 30 | Erectile dysfunction | FAERS: 1 | US FAERS | |
| 31 | Flushing | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 32 | Foreign body in respiratory tract | FAERS: 1 | US FAERS | |
| 33 | Headache | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 34 | Hypersensitivity | FAERS: 1 | US FAERS | |
| 35 | Hypotension | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 36 | Impaired gastric emptying | FAERS: 1 | US FAERS | |
| 37 | Nausea | FAERS: 1 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 38 | Overdose | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 39 | Pharmaceutical product complaint | FAERS: 1 | US FAERS | |
| 40 | Product substitution issue | FAERS: 1 | US FAERS | |
| 41 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 42 | Pruritus | FAERS: 1 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 43 | Respiratory arrest | FAERS: 1 | US FAERS | |
| 44 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 45 | Somnolence | FAERS: 1 | US FAERS | |
| 46 | Status Epilepticus | FAERS: 1 | US FAERS | |
| 47 | Suicide attempt | FAERS: 1 | US FAERS | |
| 48 | Syncope | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 49 | Therapeutic response unexpected | FAERS: 1 | US FAERS | |
| 50 | Thirst | FAERS: 1 | US FAERS | |
| 51 | Tinnitus | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 52 | Toxicity to various agents | FAERS: 1 | US FAERS | |
| 53 | Vertigo | FAERS: 1 | US FAERS | |
| 54 | Vomiting | FAERS: 1 | US FAERS | |
| 55 | Wrong technique in drug usage process | FAERS: 1 | US FAERS | |
| 56 | Acne | Canada Vigilance: 2 | Canada Vigilance | |
| 57 | Agranulocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 58 | Asthenia | Canada Vigilance: 2 | Canada Vigilance | |
| 59 | Ataxia | Canada Vigilance: 1 | Canada Vigilance | |
| 60 | Bilirubinuria | Canada Vigilance: 1 | Canada Vigilance | |
| 61 | Cardiac Arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 62 | Chest Pain | Canada Vigilance: 1 | Canada Vigilance | |
| 63 | Chills | Canada Vigilance: 2 | Canada Vigilance | |
| 64 | Completed Suicide | Canada Vigilance: 4 | Canada Vigilance | |
| 65 | Diplopia | Canada Vigilance: 1 | Canada Vigilance | |
| 66 | Dysarthria | Canada Vigilance: 1 | Canada Vigilance | |
| 67 | Dyspareunia | Canada Vigilance: 1 | Canada Vigilance | |
| 68 | Eosinophilia | Canada Vigilance: 1 | Canada Vigilance | |
| 69 | Erythema | Canada Vigilance: 3 | Canada Vigilance | |
| 70 | Eye pain | Canada Vigilance: 1 | Canada Vigilance | |
| 71 | Fatigue | Canada Vigilance: 2 | Canada Vigilance | |
| 72 | Feeling Cold | Canada Vigilance: 2 | Canada Vigilance | |
| 73 | Head discomfort | Canada Vigilance: 2 | Canada Vigilance | |
| 74 | Hyperkinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 75 | Hypomania | Canada Vigilance: 2 | Canada Vigilance | |
| 76 | Leukocytosis | Canada Vigilance: 1 | Canada Vigilance | |
| 77 | Malaise | Canada Vigilance: 1 | Canada Vigilance | |
| 78 | Memory impairment | Canada Vigilance: 1 | Canada Vigilance | |
| 79 | Myocardial Infarction | Canada Vigilance: 2 | Canada Vigilance | |
| 80 | Pallor | Canada Vigilance: 1 | Canada Vigilance | |
| 81 | Petechiae | Canada Vigilance: 1 | Canada Vigilance | |
| 82 | Polyuria | Canada Vigilance: 1 | Canada Vigilance | |
| 83 | Sepsis | Canada Vigilance: 1 | Canada Vigilance | |
| 84 | Sexual Dysfunction | Canada Vigilance: 1 | Canada Vigilance | |
| 85 | Swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 86 | Thrombocytopenia | Canada Vigilance: 2 | Canada Vigilance | |
| 87 | Urinary Retention | Canada Vigilance: 2 | Canada Vigilance | |
| 88 | Urticaria | Canada Vigilance: 7 | Canada Vigilance |
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