Insulin degludec
(FYZPCMFQCNBYCY-WIWKJPBBSA-N)
Structure
- SMILES
- NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccccc1)N)CC(=O)N)CCC(=O)N)Cc1c[nH]cn1)CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(cc1)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)CO)CC(C)C)Cc1ccc(cc1)O)CCC(=O)N)CC(C)C)CCC(=O)O)CC(=O)N)Cc1ccc(cc1)O)C(=O)N[C@H](C(=O)O)CC(=O)N)C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)O)CCCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCC(=O)O)[C@H](O)C)Cc1ccc(cc1)O)Cc1ccccc1)Cc1ccccc1)CCCNC(=N)N)CCC(=O)O)C(C)C)[C@H](O)C)CO)[C@H](CC)C)CCC(=O)N)CCC(=O)O)C(C)C)[C@H](CC)C
- Molecular Formula:
- C274H411N65O81S6
- Molecular Weight:
- 6103.970
- Log P:
- 10.0859
- Hydrogen Bond Acceptor:
- 150
- Hydrogen Bond Donor:
- 79
- TPSA:
- 2508.32
- CAS Number(s):
- 844439-96-9
Synonym(s)
1.
Insulin degludec
External Link(s)
| PubChem Compound | 118984462 |
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Blood glucose increased | FAERS: 543 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 2 | Blood glucose decreased | FAERS: 183 | US FAERS | |
| 3 | Drug ineffective | FAERS: 87 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 4 | Product quality issue | FAERS: 59 | US FAERS | |
| 5 | Diabetes mellitus inadequate control | FAERS: 54 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 6 | Nausea | FAERS: 51 | US FAERS | |
| 7 | Headache | FAERS: 49 | US FAERS | |
| 8 | Injection site pain | FAERS: 49 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 9 | Peripheral swelling | FAERS: 49 | US FAERS | |
| 10 | Pruritus | FAERS: 42 | US FAERS | |
| 11 | Device malfunction | FAERS: 38 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Product use issue | FAERS: 33 | US FAERS | |
| 13 | Device Failure | FAERS: 30 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 14 | Diabetic Ketoacidosis | FAERS: 28 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 15 | Dizziness | FAERS: 28 | US FAERS | |
| 16 | Blood glucose fluctuation | FAERS: 25 | US FAERS | |
| 17 | Malaise | FAERS: 25 | US FAERS | |
| 18 | Urticaria | FAERS: 24 | US FAERS | |
| 19 | Hypersensitivity | FAERS: 23 | US FAERS | |
| 20 | Injection site bruising | FAERS: 23 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 21 | Drug dose omission | FAERS: 21 | US FAERS | |
| 22 | Fatigue | FAERS: 21 | US FAERS | |
| 23 | Wrong technique in product usage process | FAERS: 21 | US FAERS | |
| 24 | Drug prescribing error | FAERS: 20 | US FAERS | |
| 25 | Feeling abnormal | FAERS: 20 | US FAERS | |
| 26 | Blood glucose abnormal | FAERS: 19 | US FAERS | |
| 27 | Injection Site Reaction | FAERS: 17 | US FAERS | |
| 28 | Pain | FAERS: 16 | US FAERS | |
| 29 | Tremor | FAERS: 15 | US FAERS | |
| 30 | Abdominal discomfort | FAERS: 14 | US FAERS | |
| 31 | Myalgia | FAERS: 14 | US FAERS | |
| 32 | Vomiting | FAERS: 14 | US FAERS | |
| 33 | Weight decreased | FAERS: 14 | US FAERS | |
| 34 | Incorrect dose administered | FAERS: 13 | US FAERS | |
| 35 | Injection site mass | FAERS: 13 | US FAERS | |
| 36 | Anxiety | FAERS: 12 | US FAERS | |
| 37 | Asthenia | FAERS: 12 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 38 | Injection site pruritus | FAERS: 12 | US FAERS | |
| 39 | Palpitations | FAERS: 12 | US FAERS | |
| 40 | Visual Impairment | FAERS: 12 | US FAERS | |
| 41 | Abdominal Pain | FAERS: 11 | US FAERS | |
| 42 | Cerebrovascular accident | FAERS: 11 | US FAERS | |
| 43 | Injection site urticaria | FAERS: 11 | US FAERS | |
| 44 | Joint swelling | FAERS: 11 | US FAERS | |
| 45 | Wrong technique in device usage process | FAERS: 11 | US FAERS | |
| 46 | Chest Pain | FAERS: 10 | US FAERS | |
| 47 | Constipation | FAERS: 10 | US FAERS | |
| 48 | Incorrect dose administered by device | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 49 | Injection site extravasation | FAERS: 10 | US FAERS | |
| 50 | Product storage error | FAERS: 10 | US FAERS | |
| 51 | Dehydration | FAERS: 9 | US FAERS | |
| 52 | Device leakage | FAERS: 9 | US FAERS | |
| 53 | Extra dose administered | FAERS: 9 | US FAERS | |
| 54 | Hunger | FAERS: 9 | US FAERS | |
| 55 | Intentional product misuse | FAERS: 9 | US FAERS | |
| 56 | Swelling | FAERS: 9 | US FAERS | |
| 57 | Unevaluable event | FAERS: 9 | US FAERS | |
| 58 | Alopecia | FAERS: 8 | US FAERS | |
| 59 | Injection site erythema | FAERS: 8 | US FAERS | |
| 60 | Arthralgia | FAERS: 7 | US FAERS | |
| 61 | Lethargy | FAERS: 7 | US FAERS | |
| 62 | Nasopharyngitis | FAERS: 7 | US FAERS | |
| 63 | Overdose | FAERS: 7 | US FAERS | |
| 64 | Urinary tract infection | FAERS: 7 | US FAERS | |
| 65 | Arthritis | FAERS: 6 | US FAERS | |
| 66 | Circumstance or information capable of leading to medication error | FAERS: 6 | US FAERS | |
| 67 | Disability | FAERS: 6 | US FAERS | |
| 68 | Impaired gastric emptying | FAERS: 6 | US FAERS | |
| 69 | Incorrect product storage | FAERS: 6 | US FAERS | |
| 70 | Intentional product use issue | FAERS: 6 | US FAERS | |
| 71 | Pancreatitis | FAERS: 6 | US FAERS | |
| 72 | Product dose omission | FAERS: 6 | US FAERS | |
| 73 | Somnolence | FAERS: 6 | US FAERS | |
| 74 | Suicide attempt | FAERS: 6 | US FAERS | |
| 75 | Accidental overdose | FAERS: 5 | US FAERS | |
| 76 | Back Pain | FAERS: 5 | US FAERS | |
| 77 | Burning sensation | FAERS: 5 | US FAERS | |
| 78 | Device breakage | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 79 | Diabetic metabolic decompensation | FAERS: 5 | US FAERS | |
| 80 | Epistaxis | FAERS: 5 | US FAERS | |
| 81 | Flatulence | FAERS: 5 | US FAERS | |
| 82 | Flushing | FAERS: 5 | US FAERS | |
| 83 | Lip swelling | FAERS: 5 | US FAERS | |
| 84 | Myocardial Infarction | FAERS: 5 | US FAERS | |
| 85 | Pancreatic carcinoma | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 86 | Pneumonia | FAERS: 5 | US FAERS | |
| 87 | Thirst | FAERS: 5 | US FAERS | |
| 88 | Viral upper respiratory tract infection | FAERS: 5 | US FAERS | |
| 89 | Device use error | FAERS: 4 | US FAERS | |
| 90 | Dysgeusia | FAERS: 4 | US FAERS | |
| 91 | Dyspepsia | FAERS: 4 | US FAERS | |
| 92 | Expired product administered | FAERS: 4 | US FAERS | |
| 93 | Inappropriate schedule of drug administration | FAERS: 4 | US FAERS | |
| 94 | Influenza | FAERS: 4 | US FAERS | |
| 95 | Intentional dose omission | FAERS: 4 | US FAERS | |
| 96 | Lymphadenopathy | FAERS: 4 | US FAERS | |
| 97 | Macular degeneration | FAERS: 4 | US FAERS | |
| 98 | Musculoskeletal stiffness | FAERS: 4 | US FAERS | |
| 99 | Needle issue | FAERS: 4 | US FAERS | |
| 100 | Night sweats | FAERS: 4 | US FAERS | |
| 101 | Product prescribing error | FAERS: 4 | US FAERS | |
| 102 | Accidental underdose | FAERS: 3 | US FAERS | |
| 103 | Agitation | FAERS: 3 | US FAERS | |
| 104 | Atrial Fibrillation | FAERS: 3 | US FAERS | |
| 105 | Blindness | FAERS: 3 | US FAERS | |
| 106 | Blood potassium increased | FAERS: 3 | US FAERS | |
| 107 | Bone pain | FAERS: 3 | US FAERS | |
| 108 | Cataract | FAERS: 3 | US FAERS | |
| 109 | Chest discomfort | FAERS: 3 | US FAERS | |
| 110 | Cystitis | FAERS: 3 | US FAERS | |
| 111 | Dementia | FAERS: 3 | US FAERS | |
| 112 | Epilepsy | FAERS: 3 | US FAERS | |
| 113 | Erythema | FAERS: 3 | US FAERS | |
| 114 | Eye pain | FAERS: 3 | US FAERS | |
| 115 | Injection site nodule | FAERS: 3 | US FAERS | |
| 116 | Limb injury | FAERS: 3 | US FAERS | |
| 117 | Memory impairment | FAERS: 3 | US FAERS | |
| 118 | Muscle tightness | FAERS: 3 | US FAERS | |
| 119 | Musculoskeletal Pain | FAERS: 3 | US FAERS | |
| 120 | Sinusitis | FAERS: 3 | US FAERS | |
| 121 | Skin Ulcer | FAERS: 3 | US FAERS | |
| 122 | Skin reaction | FAERS: 3 | US FAERS | |
| 123 | Thrombosis | FAERS: 3 | US FAERS | |
| 124 | Tinnitus | FAERS: 3 | US FAERS | |
| 125 | Abasia | FAERS: 2 | US FAERS | |
| 126 | Acne | FAERS: 2 | US FAERS | |
| 127 | Acute kidney injury | FAERS: 2 | US FAERS | |
| 128 | Amnesia | FAERS: 2 | US FAERS | |
| 129 | Angioedema | FAERS: 2 | US FAERS | |
| 130 | Arthropathy | FAERS: 2 | US FAERS | |
| 131 | Cardiac Arrest | FAERS: 2 | US FAERS | |
| 132 | Cardiac Flutter | FAERS: 2 | US FAERS | |
| 133 | Carpal Tunnel Syndrome | FAERS: 2 | US FAERS | |
| 134 | Cataract operation | FAERS: 2 | US FAERS | |
| 135 | Depressed Level of Consciousness | FAERS: 2 | US FAERS | |
| 136 | Diabetes Mellitus | FAERS: 2 | US FAERS | |
| 137 | Diabetic Retinopathy | FAERS: 2 | US FAERS | |
| 138 | Drug administered at inappropriate site | FAERS: 2 | US FAERS | |
| 139 | Drug administered to patient of inappropriate age | FAERS: 2 | US FAERS | |
| 140 | Drug dispensing error | FAERS: 2 | US FAERS | |
| 141 | Eructation | FAERS: 2 | US FAERS | |
| 142 | Escherichia infection | FAERS: 2 | US FAERS | |
| 143 | Feeling Cold | FAERS: 2 | US FAERS | |
| 144 | Fluid overload | FAERS: 2 | US FAERS | |
| 145 | Gait inability | FAERS: 2 | US FAERS | |
| 146 | Head discomfort | FAERS: 2 | US FAERS | |
| 147 | Hemiplegia | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 148 | Infection | FAERS: 2 | US FAERS | |
| 149 | Injection site irritation | FAERS: 2 | US FAERS | |
| 150 | Injury associated with device | FAERS: 2 | US FAERS | |
| 151 | Intentional device misuse | FAERS: 2 | US FAERS | |
| 152 | Ketoacidosis | FAERS: 2 | US FAERS | |
| 153 | Neck Pain | FAERS: 2 | US FAERS | |
| 154 | Nervousness | FAERS: 2 | US FAERS | |
| 155 | Oropharyngeal pain | FAERS: 2 | US FAERS | |
| 156 | Prescription drug used without a prescription | FAERS: 2 | US FAERS | |
| 157 | Presyncope | FAERS: 2 | US FAERS | |
| 158 | Product contamination with body fluid | FAERS: 2 | US FAERS | |
| 159 | Product dispensing error | FAERS: 2 | US FAERS | |
| 160 | Rash erythematous | FAERS: 2 | US FAERS | |
| 161 | Restless Legs Syndrome | FAERS: 2 | US FAERS | |
| 162 | Sepsis | FAERS: 2 | US FAERS | |
| 163 | Sluggishness | FAERS: 2 | US FAERS | |
| 164 | Stevens-Johnson Syndrome | FAERS: 2 | US FAERS | |
| 165 | Stress | FAERS: 2 | US FAERS | |
| 166 | Syncope | FAERS: 2 | US FAERS | |
| 167 | Therapeutic response unexpected | FAERS: 2 | US FAERS | |
| 168 | Urinary Retention | FAERS: 2 | US FAERS | |
| 169 | Vertigo | FAERS: 2 | US FAERS | |
| 170 | Vulvovaginal pruritus | FAERS: 2 | US FAERS | |
| 171 | Wrong drug administered | FAERS: 2 | US FAERS | |
| 172 | Abdominal mass | FAERS: 1 | US FAERS | |
| 173 | Abdominal tenderness | FAERS: 1 | US FAERS | |
| 174 | Activities of daily living impaired | FAERS: 1 | US FAERS | |
| 175 | Adverse event | FAERS: 1 | US FAERS | |
| 176 | Ageusia | FAERS: 1 | US FAERS | |
| 177 | Akinesia | FAERS: 1 | US FAERS | |
| 178 | Amputation | FAERS: 1 | US FAERS | |
| 179 | Anaphylactic shock | FAERS: 1 | US FAERS | |
| 180 | Anembryonic gestation | FAERS: 1 | US FAERS | |
| 181 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 182 | Ankle Fracture | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 183 | Antipsychotic drug level increased | FAERS: 1 | US FAERS | |
| 184 | Aphonia | FAERS: 1 | US FAERS | |
| 185 | Apparent life threatening event | FAERS: 1 | US FAERS | |
| 186 | Aspartate Aminotransferase Increased | FAERS: 1 | US FAERS | |
| 187 | Asthma | FAERS: 1 | US FAERS | |
| 188 | Atypical pneumonia | FAERS: 1 | US FAERS | |
| 189 | Bed rest | FAERS: 1 | US FAERS | |
| 190 | Bedridden | FAERS: 1 | US FAERS | |
| 191 | Blood cholesterol increased | FAERS: 1 | US FAERS | |
| 192 | Blood creatinine increased | FAERS: 1 | US FAERS | |
| 193 | Blood iron abnormal | FAERS: 1 | US FAERS | |
| 194 | Blood ketone body present | FAERS: 1 | US FAERS | |
| 195 | Blood potassium abnormal | FAERS: 1 | US FAERS | |
| 196 | Blood potassium decreased | FAERS: 1 | US FAERS | |
| 197 | Blood sodium decreased | FAERS: 1 | US FAERS | |
| 198 | Brain Hypoxia | FAERS: 1 | US FAERS | |
| 199 | Breast procedural complication | FAERS: 1 | US FAERS | |
| 200 | Breast tenderness | FAERS: 1 | US FAERS | |
| 201 | Bronchitis | FAERS: 1 | US FAERS | |
| 202 | Carotid artery occlusion | FAERS: 1 | US FAERS | |
| 203 | Cellulitis | FAERS: 1 | US FAERS | |
| 204 | Chills | FAERS: 1 | US FAERS | |
| 205 | Choking | FAERS: 1 | US FAERS | |
| 206 | Chromatopsia | FAERS: 1 | US FAERS | |
| 207 | Chromaturia | FAERS: 1 | US FAERS | |
| 208 | Clostridium difficile infection | FAERS: 1 | US FAERS | |
| 209 | Cold sweat | FAERS: 1 | US FAERS | |
| 210 | Colitis | FAERS: 1 | US FAERS | |
| 211 | Completed Suicide | FAERS: 1 | US FAERS | |
| 212 | Complication associated with device | FAERS: 1 | US FAERS | |
| 213 | Congenital absence of cranial vault | FAERS: 1 | US FAERS | |
| 214 | Coronary Artery Disease | FAERS: 1 | US FAERS | |
| 215 | Dark circles under eyes | FAERS: 1 | US FAERS | |
| 216 | Dawn phenomenon | FAERS: 1 | US FAERS | |
| 217 | Deafness | FAERS: 1 | US FAERS | |
| 218 | Dermatitis acneiform | FAERS: 1 | US FAERS | |
| 219 | Dermatitis | FAERS: 1 | US FAERS | |
| 220 | Diabetes mellitus management | FAERS: 1 | US FAERS | |
| 221 | Diabetic Foot | FAERS: 1 | US FAERS | |
| 222 | Discomfort | FAERS: 1 | US FAERS | |
| 223 | Drug abuse | FAERS: 1 | US FAERS | |
| 224 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 225 | Drug effect variable | FAERS: 1 | US FAERS | |
| 226 | Dysarthria | FAERS: 1 | US FAERS | |
| 227 | Dysphonia | FAERS: 1 | US FAERS | |
| 228 | Ear discomfort | FAERS: 1 | US FAERS | |
| 229 | Eating disorder symptom | FAERS: 1 | US FAERS | |
| 230 | Ejection Fraction Decreased | FAERS: 1 | US FAERS | |
| 231 | Embolism | FAERS: 1 | US FAERS | |
| 232 | Enuresis | FAERS: 1 | US FAERS | |
| 233 | Eye irritation | FAERS: 1 | US FAERS | |
| 234 | Fat redistribution | FAERS: 1 | US FAERS | |
| 235 | Fibromyalgia | FAERS: 1 | US FAERS | |
| 236 | Gastritis | FAERS: 1 | US FAERS | |
| 237 | Gastroenteritis | FAERS: 1 | US FAERS | |
| 238 | Genital discomfort | FAERS: 1 | US FAERS | |
| 239 | Genital erosion | FAERS: 1 | US FAERS | |
| 240 | Genital pain | FAERS: 1 | US FAERS | |
| 241 | Genital swelling | FAERS: 1 | US FAERS | |
| 242 | Glaucoma | FAERS: 1 | US FAERS | |
| 243 | Grip strength decreased | FAERS: 1 | US FAERS | |
| 244 | Hepatomegaly | FAERS: 1 | US FAERS | |
| 245 | Hospice Care | FAERS: 1 | US FAERS | |
| 246 | Hyperkeratosis | FAERS: 1 | US FAERS | |
| 247 | Hyperphagia | FAERS: 1 | US FAERS | |
| 248 | Hypersomnia | FAERS: 1 | US FAERS | |
| 249 | Hypertensive crisis | FAERS: 1 | US FAERS | |
| 250 | Hyperthyroidism | FAERS: 1 | US FAERS | |
| 251 | Hypotension | FAERS: 1 | US FAERS | |
| 252 | Inappropriate schedule of product administration | FAERS: 1 | US FAERS | |
| 253 | Incoherent | FAERS: 1 | US FAERS | |
| 254 | Incorrect route of drug administration | FAERS: 1 | US FAERS | |
| 255 | Inflammation | FAERS: 1 | US FAERS | |
| 256 | Injected limb mobility decreased | FAERS: 1 | US FAERS | |
| 257 | Injection site cellulitis | FAERS: 1 | US FAERS | |
| 258 | Injection site granuloma | FAERS: 1 | US FAERS | |
| 259 | Injection site hypersensitivity | FAERS: 1 | US FAERS | |
| 260 | Injection site hypertrophy | FAERS: 1 | US FAERS | |
| 261 | Injection site pallor | FAERS: 1 | US FAERS | |
| 262 | Injection site scar | FAERS: 1 | US FAERS | |
| 263 | Injection site vesicles | FAERS: 1 | US FAERS | |
| 264 | Insulin Resistance | FAERS: 1 | US FAERS | |
| 265 | Intercepted drug prescribing error | FAERS: 1 | US FAERS | |
| 266 | Intercepted medication error | FAERS: 1 | US FAERS | |
| 267 | Ketosis | FAERS: 1 | US FAERS | |
| 268 | Leukocytosis | FAERS: 1 | US FAERS | |
| 269 | Limb crushing injury | FAERS: 1 | US FAERS | |
| 270 | Limb discomfort | FAERS: 1 | US FAERS | |
| 271 | Lip pruritus | FAERS: 1 | US FAERS | |
| 272 | Lipodystrophy acquired | FAERS: 1 | US FAERS | |
| 273 | Liquid product physical issue | FAERS: 1 | US FAERS | |
| 274 | Lower respiratory tract infection | FAERS: 1 | US FAERS | |
| 275 | Lymphoma | FAERS: 1 | US FAERS | |
| 276 | Malabsorption from administration site | FAERS: 1 | US FAERS | |
| 277 | Mental impairment | FAERS: 1 | US FAERS | |
| 278 | Mental status changes | FAERS: 1 | US FAERS | |
| 279 | Metastatic Neoplasm | FAERS: 1 | US FAERS | |
| 280 | Multiple Sclerosis | FAERS: 1 | US FAERS | |
| 281 | Muscle strain | FAERS: 1 | US FAERS | |
| 282 | Myasthenia Gravis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 283 | Nephrectomy | FAERS: 1 | US FAERS | |
| 284 | Nephrolithiasis | FAERS: 1 | US FAERS | |
| 285 | Nerve injury | FAERS: 1 | US FAERS | |
| 286 | Nodule | FAERS: 1 | US FAERS | |
| 287 | Onychoclasis | FAERS: 1 | US FAERS | |
| 288 | Optic Neuritis | FAERS: 1 | US FAERS | |
| 289 | Oral cavity cancer metastatic | FAERS: 1 | US FAERS | |
| 290 | Oral infection | FAERS: 1 | US FAERS | |
| 291 | Oral pain | FAERS: 1 | US FAERS | |
| 292 | Osteoporosis | FAERS: 1 | US FAERS | |
| 293 | Overweight | FAERS: 1 | US FAERS | |
| 294 | Pancreatectomy | FAERS: 1 | US FAERS | |
| 295 | Pancreatic Neoplasm | FAERS: 1 | US FAERS | |
| 296 | Paternal exposure during pregnancy | FAERS: 1 | US FAERS | |
| 297 | Pelvic Pain | FAERS: 1 | US FAERS | |
| 298 | Peritoneal Dialysis | FAERS: 1 | US FAERS | |
| 299 | Physical assault | FAERS: 1 | US FAERS | |
| 300 | Pityriasis Rosea | FAERS: 1 | US FAERS | |
| 301 | Poor quality sleep | FAERS: 1 | US FAERS | |
| 302 | Pre-Eclampsia | FAERS: 1 | US FAERS | |
| 303 | Pregnancy | FAERS: 1 | US FAERS | |
| 304 | Product administration error | FAERS: 1 | US FAERS | |
| 305 | Product complaint | FAERS: 1 | US FAERS | |
| 306 | Product container seal issue | FAERS: 1 | US FAERS | |
| 307 | Product label confusion | FAERS: 1 | US FAERS | |
| 308 | Product label issue | FAERS: 1 | US FAERS | |
| 309 | Product measured potency issue | FAERS: 1 | US FAERS | |
| 310 | Product physical issue | FAERS: 1 | US FAERS | |
| 311 | Product use in unapproved indication | FAERS: 1 | US FAERS | |
| 312 | Pulmonary Embolism | FAERS: 1 | US FAERS | |
| 313 | Pulmonary Fibrosis | FAERS: 1 | US FAERS | |
| 314 | Rehabilitation therapy | FAERS: 1 | US FAERS | |
| 315 | Renal pain | FAERS: 1 | US FAERS | |
| 316 | Retinal vascular occlusion | FAERS: 1 | US FAERS | |
| 317 | Rotator cuff syndrome | FAERS: 1 | US FAERS | |
| 318 | Sarcoidosis | FAERS: 1 | US FAERS | |
| 319 | Screaming | FAERS: 1 | US FAERS | |
| 320 | Septic Shock | FAERS: 1 | US FAERS | |
| 321 | Sinus headache | FAERS: 1 | US FAERS | |
| 322 | Skeletal dysplasia | FAERS: 1 | US FAERS | |
| 323 | Skin hypertrophy | FAERS: 1 | US FAERS | |
| 324 | Skin lesion | FAERS: 1 | US FAERS | |
| 325 | Sneezing | FAERS: 1 | US FAERS | |
| 326 | Spondylitis | FAERS: 1 | US FAERS | |
| 327 | Stomatitis | FAERS: 1 | US FAERS | |
| 328 | Sudden onset of sleep | FAERS: 1 | US FAERS | |
| 329 | Suicide threat | FAERS: 1 | US FAERS | |
| 330 | Sunburn | FAERS: 1 | US FAERS | |
| 331 | Supportive care | FAERS: 1 | US FAERS | |
| 332 | Suspected product contamination | FAERS: 1 | US FAERS | |
| 333 | Teeth brittle | FAERS: 1 | US FAERS | |
| 334 | Temporal Arteritis | FAERS: 1 | US FAERS | |
| 335 | Therapeutic response delayed | FAERS: 1 | US FAERS | |
| 336 | Therapy non-responder | FAERS: 1 | US FAERS | |
| 337 | Tooth Extraction | FAERS: 1 | US FAERS | |
| 338 | Toothache | FAERS: 1 | US FAERS | |
| 339 | Transaminases increased | FAERS: 1 | US FAERS | |
| 340 | Transcription medication error | FAERS: 1 | US FAERS | |
| 341 | Tympanic Membrane Perforation | FAERS: 1 | US FAERS | |
| 342 | Underweight | FAERS: 1 | US FAERS | |
| 343 | Upper-airway cough syndrome | FAERS: 1 | US FAERS | |
| 344 | Urinary Incontinence | FAERS: 1 | US FAERS | |
| 345 | Uterine contractions during pregnancy | FAERS: 1 | US FAERS | |
| 346 | Vitreous floaters | FAERS: 1 | US FAERS | |
| 347 | Wheezing | FAERS: 1 | US FAERS | |
| 348 | cancer surgery | FAERS: 1 | US FAERS | |
| 349 | furuncle | FAERS: 1 | US FAERS | |
| 350 | Angioplasty | Canada Vigilance: 1 | Canada Vigilance |
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